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Content-Based Image Retrieval of Chest CT with Convolutional Neural Network for Diffuse Interstitial Lung Disease: Performance Assessment in Three Major Idiopathic Interstitial Pneumonias

  • Hye Jeon Hwang;Joon Beom Seo;Sang Min Lee;Eun Young Kim;Beomhee Park;Hyun-Jin Bae;Namkug Kim
    • Korean Journal of Radiology
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    • v.22 no.2
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    • pp.281-290
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    • 2021
  • Objective: To assess the performance of content-based image retrieval (CBIR) of chest CT for diffuse interstitial lung disease (DILD). Materials and Methods: The database was comprised by 246 pairs of chest CTs (initial and follow-up CTs within two years) from 246 patients with usual interstitial pneumonia (UIP, n = 100), nonspecific interstitial pneumonia (NSIP, n = 101), and cryptogenic organic pneumonia (COP, n = 45). Sixty cases (30-UIP, 20-NSIP, and 10-COP) were selected as the queries. The CBIR retrieved five similar CTs as a query from the database by comparing six image patterns (honeycombing, reticular opacity, emphysema, ground-glass opacity, consolidation and normal lung) of DILD, which were automatically quantified and classified by a convolutional neural network. We assessed the rates of retrieving the same pairs of query CTs, and the number of CTs with the same disease class as query CTs in top 1-5 retrievals. Chest radiologists evaluated the similarity between retrieved CTs and queries using a 5-scale grading system (5-almost identical; 4-same disease; 3-likelihood of same disease is half; 2-likely different; and 1-different disease). Results: The rate of retrieving the same pairs of query CTs in top 1 retrieval was 61.7% (37/60) and in top 1-5 retrievals was 81.7% (49/60). The CBIR retrieved the same pairs of query CTs more in UIP compared to NSIP and COP (p = 0.008 and 0.002). On average, it retrieved 4.17 of five similar CTs from the same disease class. Radiologists rated 71.3% to 73.0% of the retrieved CTs with a similarity score of 4 or 5. Conclusion: The proposed CBIR system showed good performance for retrieving chest CTs showing similar patterns for DILD.

The Effect of Cooperative Small Group Discussion in Science Concept Learning (과학 개념 학습에서 협동적 소집단 토론의 효과)

  • Kang, Suk-Jin;Han, Su-Jin;Noh, Tae-Hee
    • Journal of The Korean Association For Science Education
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    • v.22 no.1
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    • pp.93-101
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    • 2002
  • This study investigated the effect of small group discussion for science concept learning in cooperative learning environments that encourage verbal interaction with peers upon students' understanding of the concepts at the particulate level, application abilities, perceptions of students' negotiation, and communication apprehension. Two classes of 7th grade at a coed middle school were assigned to the control and the treatment groups. They were taught about change of states and motion of molecules for 7 class periods. Two-way ANCOVA results revealed that the scores of a conceptions test for the treatment group were significantly higher than those for the control group, and that the low-achievers in the treatment group performed better than those in the control group. However, the scores of two groups did not differ significantly in an application test. The perceptions of students' negotiation for the treatment group were more positive, but the scores of the communication apprehension for two groups were not significantly different.

Estimating the Economic Value of the Songieong Beach Using A Count Data Model: - Off-season Estimating Value of the Beach - (가산자료모형을 이용한 송정 해수욕장의 경제적 가치추정: - 비수기 해수욕장의 가치추정 -)

  • Heo, Yun-Jeong;Lee, Seung-Lae
    • The Journal of Fisheries Business Administration
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    • v.38 no.2
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    • pp.79-101
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    • 2007
  • The purpose of this study is to estimate the economic value of the Songieong Beach in Off-season, using a Individual Travel Cost Model(ITCM). Songieong Beach is located in Busan but far away from city. These days, however, the increased rate of traffic inflow to the Songieong beach and the five-day working week are reflected in the trend analysis. Moreover, people have changed psychological value. For that reason, visitors are on the increase on the beach in off-season. The ITCM is applied to estimate non-market value or environmental Good like a Contingent Valuation Method and Hedonic Price Model etc. The ITCM was derived from the Count Data Model(i.e. Poisson and Negative Binomial model). So this paper compares Poisson and negative binomial count data models to measure the tourism demands. The data for the study were collected from the Songjeong Beach on visitors over the a week from November 1 through November 23, 2006. Interviewers were instructed to interview only individuals. So the sample was taken in 113. A dependent variable that is defined on the non-negative integers and subject to sampling truncation is the result of a truncated count data process. This paper analyzes the effects of determinants on visitors' demand for exhibition using a class of maximum-likelihood regression estimators for count data from truncated samples, The count data and truncated models are used primarily to explain non-negative integer and truncation properties of tourist trips as suggested by the economic valuation literature. The results suggest that the truncated negative binomial model is improved overdispersion problem and more preferred than the other models in the study. This paper is not the same as the others. One thing is that Estimating Value of the Beach in off-season. The other thing is this study emphasizes in particular 'travel cost' that is not only monetary cost but also including opportunity cost of 'travel time'. According to the truncated negative binomial model, estimates the Consumer Surplus(CS) values per trip of about 199,754 Korean won and the total economic value was estimated to be 1,288,680 Korean won.

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A Study on the Teaching and Learning of Discrete Mathematics in the 7th Mathematics Curriculum (제7차 교육과정의 이산수학 교수-학습에 관한 연구)

  • Kim Nam Hee
    • School Mathematics
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    • v.7 no.1
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    • pp.77-101
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    • 2005
  • This study is a discussion of the teaching and learning of discrete mathematics in school mathematics. In this study, we summarized the importance of discrete mathematics m school mathematics. And we examined instruction methods of discrete mathematics expressed in the 7th mathematics curriculum. On the basis of analysis for teaching cases in previous studies, we proposed four suggestions to organize discrete mathematics classroom. That is as follows. First, discrete mathematics needs to be introduced as a mathematical modeling of real-world problem. Second, algorithm learning in discrete mathematics have to be accomplished with computer experiments. Third, when we solve a problem with discrete data, we need to consider discrete property of given data. Forth, discrete mathematics class must be full of investigation and discussion among students. In each suggestion, we dealt with detailed examples including educational ideas in order to helping mathematics teacher orgainzing discrete mathematics classroom.

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Clinical Analysis of Cardiac Valve Surgery (심장판막증의 외과적 치료)

  • 김형묵
    • Journal of Chest Surgery
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    • v.18 no.3
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    • pp.446-455
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    • 1985
  • A total and consecutive 156 patients have undergone cardiac valve surgery including 13 closed mitral commissurotomy, 13 open mitral commissurotomy, one mitral annuloplasty, 75 mitral valve replacement, one aortic annuloplasty, 24 aortic valve replacement, 3 tricuspid valve replacement, 25 double valve replacement and one triple valve replacement. 155 prosthetic valves were replaced in a period between September 1976 and August 1985. There were 68 males and 88 females with age range from 8 to 69 yrs [mean 36.5 yr]. Out of replaced valves, 61 was tissue valve including 54 Carpentier-Edwards, and 4 was mechanical valves including 74 St. Jude Medical, and the position replaced was 101 valves for mitral, 46 for aortic and 8 for tricuspid. Single valve replacement in 102 cases, double valve replacement in 25 cases [17 for AVR+MVR, and 8 for MVR+TVR], and only one case was noted in the triple valve replacement. Early mortality within 30 days after operation was noted in 11 cases [7%]; 7 after MVR, 2 after DVR, and each one after open mitral commissurotomy and mitral annuloplasty. Cause of death was valve thrombus, cerebral air embolism, low output syndrome, uncontrollable arrhythmia, parapneumonic sepsis, acute cardiac tamponade and left atrial rupture. 7 late deaths were noted during the follow-up period from 1 to 104 months [average 48 month]; three due to valve and left atrial thrombus formation, two due to CVA from overdose of warfarin, and each one due to congestive heart failure and chronic constrictive pericarditis, Anticoagulants after prosthetic valve replacement were maintained with warfarin, dipyridamole and aspirin to the level of around 50% of normal prothrombin time in 79 cases, and Ticlopidine with aspirin in 47 cases to compare the result of each group. There were 11 major thromboembolic episodes including 3 deaths in the warfarin group. Two cases of CVA due to overdose of warfarin was noted in the warfarin group. In the ticlopidine group, there was only one left atrial thrombus confirmed at the time of autopsy. Among the survived 138 cases, nearly all cases[136 cases] were included in NYHA functional class I and II during the follow-up period. In conclusion, surgical treatment of the cardiac valve disease in 156 clinical cases revealed excellent result with acceptable operative risk and late mortality. Prevention of thrombus formation with anti-platelet aggregator Ticlopidine has better result than warfarin group presently with no specific side effect such as bleeding or gastrointestinal trouble.

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Software Development for the Performance Evaluation and Blade Design of a HACT by BEMT (블레이드요소 운동량 이론에 의한 수평축 조류발전용 터빈 블레이드 설계 및 성능평가 소프트웨어 개발)

  • Mo, Jang-Oh;Kim, Mann-Eung;Hyun, Beom-Soo;Kim, You-Taek;Oh, Cheol;Lee, Young-Ho
    • Journal of Advanced Marine Engineering and Technology
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    • v.35 no.1
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    • pp.96-101
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    • 2011
  • In this study, we have established the design techniques, with which we can design and evaluate performance of blades on a horizontal axis current turbine, by application of blade element momentum theory considering the blade tip's loss model, and finally developed the domestic software(MCT-blade V2.0). We have designed and evaluated performance of blades for the 2MW class by using of the software, and confirmed its calculation results from BEMT by comparing those results from commercial code of ANSYS FLUENT. In a state of rated velocity 2.5m/s, the mechanical power from BEMT is calculated as 2,121kW, which is considered to satisfy the electrical power, but the value from CFD is calculated as 1,901kW, which is considered a little deficient for the target output.

Effects of Short-Term Food Additive Nutrition Education Including Hands-on Activities on Food Label Use and Processed-Food Consumption Behaviors: among 5th Grade Elementary School Students (실험활동을 활용한 단기 식품첨가물 영양교육이 식품표시 이용 및 가공식품섭취 행동에 미치는 효과: 서울시 일부 초등학교 5학년생을 대상으로)

  • Kim, Ji-Hye;Lee, Seung-Min
    • Korean Journal of Community Nutrition
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    • v.16 no.5
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    • pp.539-547
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    • 2011
  • This study evaluated effects of food additive nutrition education on food additives-related knowledge, subjective awareness, and perception and dietary behaviors of food label use and processed-food intake. The study subjects were 5th grade students attending an elementary school in Seoul. A total of 101 subjects were assigned to either education (N = 50) or control (N = 51) group, and 3 food additive nutrition education classes were implemented to the education group. Self-administered questionnaires were collected from all the participants twice, a week before and after the nutrition education to compare the changes between two groups. The food additives-related knowledge and subjective awareness significantly improved in the education group compared to the control group. The changes in perceived harmfulness and perceived necessity for taste were also detected significantly different between the two groups, with more positive changes in the education group. Dietary behaviors of checking food labels and trying to purchase processed-foods with less food additives improved in the education group at a significant level in comparison with the control group. Additionally changes in intake frequency of several processed-food items were significantly different between the groups, again in a more positive direction in the education group. The study findings showed short-term food-additive nutrition education including hands-on activities could positively modify elementary school children's food additives-related knowledge, perception, and certain dietary behaviors, stressing better settlement of in-class nutrition education within an elementary school's education curriculum.

Cloning and Molecular Characterization of ${\beta}$-1,3-Glucan Synthase from Sparassis crispa

  • Yang, Yun Hui;Kang, Hyeon-Woo;Ro, Hyeon-Su
    • Mycobiology
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    • v.42 no.2
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    • pp.167-173
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    • 2014
  • A ${\beta}$-glucan synthase gene was isolated from the genomic DNA of polypore mushroom Sparassis crispa, which reportedly produces unusually high amount of soluble ${\beta}$-1,3-glucan (${\beta}$-glucan). Sequencing and subsequent open reading frame analysis of the isolated gene revealed that the gene (5,502 bp) consisted of 10 exons separated by nine introns. The predicted mRNA encoded a ${\beta}$-glucan synthase protein, consisting of 1,576 amino acid residues. Comparison of the predicted protein sequence with multiple fungal ${\beta}$-glucan synthases estimated that the isolated gene contained a complete N-terminus but was lacking approximately 70 amino acid residues in the C-terminus. Fungal ${\beta}$-glucan synthases are integral membrane proteins, containing the two catalytic and two transmembrane domains. The lacking C-terminal part of S. crispa ${\beta}$-glucan synthase was estimated to include catalytically insignificant transmembrane ${\alpha}$-helices and loops. Sequence analysis of 101 fungal ${\beta}$-glucan synthases, obtained from public databases, revealed that the ${\beta}$-glucan synthases with various fungal origins were categorized into corresponding fungal groups in the classification system. Interestingly, mushrooms belonging to the class Agaricomycetes were found to contain two distinct types (Type I and II) of ${\beta}$-glucan synthases with the type-specific sequence signatures in the loop regions. S. crispa ${\beta}$-glucan synthase in this study belonged to Type II family, meaning Type I ${\beta}$-glucan synthase is expected to be discovered in S. crispa. The high productivity of soluble ${\beta}$-glucan was not explained but detailed biochemical studies on the catalytic loop domain in the S. crispa ${\beta}$-glucan synthase will provide better explanations.

Effect of HAZ Softening Zone on Creep Rupture Properties of 1.0Cr-1.0Mo-0.25V Turbine Steels -Part II : Carbide Morphology- (1.0Cr-1.0Mo-0.25V 터어빈 로터강의 열영향부 연화층이 크립 파단 특성에 미치는 영향 - Part II : 탄화물 형태 -)

  • ;Indacochea, J. E.
    • Journal of Welding and Joining
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    • v.15 no.1
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    • pp.101-108
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    • 1997
  • In repaired weldment of ASTM A-470 class 8 high pressure stream turbine rotor steel, creep rupture life was studied in relation with carbide morphology. Carbides were identified using carbide extraction replica method. A retired rotor has molybdenum rich carbide $M_2C$, lndacochea vanadium rich carbide $M_4C_3$, and chromium rich carbides $M_{23}C_6$and $M_7C_3$. Weldments ruptured at ICHAZ showed that some of carbides have been transformed into spherical types of coarsened carbides at ruptured area. Those carbides were revealed as molybdenum rich $M_6C$ carbide and they provided cavitation sites due to molybdenum depletion around $(M_6C)$ carbide. However coarsened $M_6C$ and $M_{23}C_6$ carbides were observed at ruptured area in case of ruptured at CGHAZ.

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Analysis the actual Conditions for the Effect Management on Livelihood Environment Forest Protected Areas (생활환경보호구역의 효율적 산림관리를 위한 실태 분석)

  • Park, Jae Hyeon;Lee, Sang Tae
    • Journal of Korean Society of Forest Science
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    • v.101 no.2
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    • pp.279-285
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    • 2012
  • This study was conducted to offer preliminary data for forest management from March and December 2011. Based on the number of standing trees by DBH classes, it is recommended to practice thinning and pruning to change the current young stand to mature stand. In Livelihood Environment Forest Protected Areas, young (0-10 years or 0-10 cm DBH) and detected trees need to be removed and selected healthy trees need to be heavily tended. Also, selected trees in age 20-30 (20-30 cm DBH class) need to receive concentrated tending. Since Livelihood Environment Forest Protected Areas had been vulnerable for erosion, the diversity of understory layer is low. In order to diversify deciduous trees, it is recommended to introduce new species and thin and prune existing trees. It is not proper to adapt clear cutting in a short time and should be partially regenerated using shelter-wood method or proper tending practices to the Pinus rigida dominanted forest. Tending existing under-story species including Quercus alina, Quercus variabilis, and Quercus serrata would be important.