• The Journal of Internal Korean Medicine
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• v.27 no.4
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• pp.962-968
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• 2006

Background : Liver cirrhosis is a disease of the liver in which normal cells are replaced by scar tissue. This condition results in the failure of the liver to perform many of its usual functions. Liver cirrhosis includes ascites, jaundice, portal hypertension, varices etc. Objectives : This study was to see if there is a decrease in ascites of liver cirrhosis to under acupuncture and herbal treatment to test their validity. Methods : Measuring the response to treatment of ascites by giving pyengwie-san hap wieryungtang gamibang and treating the patient with acupuncture, these clinical symptoms were observed: weight, abdominal circumference, abdominal SONO, chest X-ray, and lab findings. Results : Over 18 days the daily average loss of weight and abdominal circumference 0.43kg and 0.56cm, respectively. Lab findings of liver functions showed improvement. Conclusions : This report shows a role for acupuncture and herbal treatment for treating ascites in liver cirrhosis.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.1
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• pp.306-309
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• 2004

Liver cirrhosis is caused by virus, alcohol, toxins, drugs and chronic hepatitis. Clinical symptoms of liver cirrhosis are severe fatigue, nausea, fever, dyspepsia, anorexia, RUQ pain, jaundice, ascites. We applied oriental medicines to patient who had chronic hepatitis and liver cirrhosis. Sodalgeonbitang-gamibang has been used to treat hepatitis and liver cirrhosis because of its beneficial effects. The patient symptoms began to improve after about one month of treatment. After medication we could find remarkable effect on clinical symptoms and blood test. So we hope that this clinical study is helpful in treat a patient with hepatic disease.

• The Journal of Internal Korean Medicine
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• v.41 no.3
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• pp.515-522
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• 2020

Objectives: This study aimed to describe whether Saenggangunbi-tang supports clinical management of a patient with decompensated liver cirrhosis without unfavorable side effects. Methods: A 78-year-old woman diagnosed with unspecified liver cirrhosis in 2014, who had undergone abdominal paracentesis twice until 2014 and variceal ligation twice until 2017, took Saenggangunbi-tang from July 25, 2019 to March 23, 2020. We observed clinical changes, such as fatigue, leg edema, and gingival bleeding, as well as laboratory findings. Results: After taking Saenggangunbi-tang for about eight months, the patient's symptoms and serum levels of liver enzymes were improved in comparison to her symptoms and serum levels at the first visit. Moreover, there was no occurrence of any complications, such as ascites and gastroesophageal variceal bleeding by portal hypertension. Conclusions: This study suggests that Saenggangunbi-tang might be effective in the treatment of decompensated liver cirrhosis.

• Tuberculosis and Respiratory Diseases
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• v.44 no.3
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• pp.639-648
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• 1997

Background : Arterial hypoxemia has been noted in patients with liver cirrhosis because of bronchial vessel dilatation. Cabenes et al. reported that bronchial hyperresponsiveness to the metacholine inhalation was observed in patients of left side heart failure, he suggested that one of the mechanism was bronchial vessel dilatation. We hypothesized that patients of liver cirrhosis might have bronchial hyperresponsiveness to metacholine inhalation due to portal hypertension. We evaluate the relationship between bronchial responsiveness and severity of liver cirrhosis, severity of portal hypertension. Methods : In the 22 patients of the liver cirrhosis with clinical portal hypertension, metacholine provocation test was done and determined $PC_{20}FEV1$. We classified liver cirrhosis according to Pugh-Child classification. Esophagogastroscopies were performed for the evaluation of the relationship between bronchial hyperresponsiveness and severity of esophageal varix. Results : In the 22 cases of the liver cirrhosis with clinical portal hypertension. The causes of liver cirrhosis, alcoholic hepatitis was 9 cases, hepatitis B virus was 12 cases, hepatitis C virus was 1 case, and 151 cases (68.18%) of total 22 cases were positive in metacholine provocation test. In positive cases. There was no significant relationship between $PC_{20}FEV1$ and severity of liver cirrhosis which were classified by Pugh-Child classification or severity of esophageal varix(p<0.05). Conclusion : we observed that bronchial responsiveness to metacholine increased in the patients of liver cirrhosis and there was no significant relationship between the severity of liver cirrhosis and the severity of esophageal varix.

• Journal of KIISE:Software and Applications
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• v.32 no.6
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• pp.532-541
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• 2005

We examined the wave pattern of the spleen by using abdominal CT images of a patient with liver cirrhosis, and found that they are different from those of a person with a normal liver. In the abdominal CT image of the patient with liver cirrhosis, there is a deep wave part on the left side of the spleen. In the case of the normal liver, there are waves on the left side, but they aren't deep. Therefore, the total area of waving parts of the spleen with liver cirrhosis is found to be greater than that of the spleen with the normal liver. Moreover, when examining circularity by abstracting the waves of the spleen from the image with liver cirrhosis, we found they are more circular than those of the spleen accompanied by a normal liver. This paper suggests an automatic method to diagnose liver cirrhosis by using the wave pattern of the spleen in abdominal CT images on the basis of the two principles. It tells us that we can judge if the liver has liver cirrhosis automatically, without the manual test of the ratio of caudate lobe to right lobe, only with the spleen.

• The Korean Journal of Nuclear Medicine
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• v.5 no.2
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• pp.7-18
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• 1971

The liver function test was performed by means of two radioisotope tracer techniques in 20 normal subjects and in 63 patients with hepatobiliary diseases. The blood disappearance rates of $^{131}I$-rose bengal and of $^{198}Au$ colloid were determined by external counting method. The hepatocellular function and the hepatic blood flow were estimated from the observed data and the results were compared with those of the conventional liver function tests. The results obtained were as follows: 1. The mean blood disappearance half time of $^{131}I$-rose bengal was $6.6{\pm}0.63$ minutes in normal control, $17.7{\pm}6.93$ in cirrhosis of the liver, $16.6{\pm}4.80$ in acute hepatitis, and $14.7{\pm}3.46$ in obstructive jaundice. It was markedly prolonged in the hepatobiliary diseases as compared with the normal control, but there was no significant difference among the hepatobiliary diseases. 2. The mean blood disappearance half time of $^{198}Au$ colloid was $4.0{\pm}0.66$ minutes in normal control, $9.8{\pm}3.42$ in cirrhosis of the liver, $4.4{\pm}0.82$ in acute hepatitis, and $5.0{\pm}1.42$ in obstructive jaundice. The difference between cirrhosis of the liver and normal control Was statistically significant. However, there was no definite difference among acute hepatitis, obstructive jaundice, and normal control. The mean blood disappearance rate constant (K value) was $0.177{\pm}0.028/minute$ in normal control. In cirrhosis of the liver, it was markedly decreased which was suggestive of the reduced hepatic blood flow. 3. The ratio of $^{131}I$-rose bengal blood disappearance half time to $^{198}Au$ colloid disappearance half time was $1.68{\pm}0.20$ in normal control, $1.82{\pm}0.31$ in cirrhosis of the liver, $3.80{\pm}0.82$ in acute hepatitis, and $3.01{\pm}0.54$ in obstructive jaundice. The ratios in acute hepatitis and obstructive jaundice were remarkably higher than those in normal control and cirrhosis of the liver. 4. There was a significant correlation between the blood disappearance half time of $^{131}I$-rose bengal and that of $^{198}Au$ colloid in cirrhosis of the liver. 5. In cirrhosis of the liver, the blood disappearance half times of $^{131}I$-rose bengal and of $^{198}Au$ colloid were inversely correlated to the serum albumin level. In acute hepatitis, there was a good positive correlation between the blood disappearance half time of $^{131}I$-rose bengal and the serum transaminase activities. In obstructive jaundice, the blood disappearance half time of $^{131}I$-rose bengal was correlated to the serum bilirubin level.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.5
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• pp.111-120
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• 2020

This study examined the factors affecting the readmission of patients with liver cirrhosis, and focused on self-care, social support, and drinking refusal self-efficacy. The subjects were 75 cirrhosis patients who were admitted to medium-sized hospitals at S-city for two months from May 2019 to June 2019. The data was analyzed with the SPSS (Version 25) program, and logistic regression analysis was performed on the factors affecting readmission. The results were self-care (27.49±0.53 out of 60), social support (52.80±16.44 out of 90), and drinking refusal self-efficacy (42.39±22.76 out of 80). The readmission method was classified into planned and unplanned admissions. Unplanned readmission was found to differ depending on the drinking experience (OR: 4.16) and the presence of complications (OR: 5.11) within a month of discharge rather than that of the planned readmissions, accounted for 19.7%. It will be very important to reduce the occurrence of complications by early management of patients with cirrhosis, and increase the drinking refusal self-efficacy, and so reduce unplanned readmission and prevent the progression and deterioration of cirrhosis. The drinking experience and the occurrence of complications can be reduced through interventions that increase self-care, social support, and drinking refusal self-efficacy. Nursing interventions are needed to prevent patients with cirrhosis from drinking and to manage the complications due to relapse into alcoholism.

• Journal of Sasang Constitutional Medicine
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• v.17 no.3
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• pp.135-141
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• 2005

1. Objectives The purpose of this case is to report that a soeumin patient diagnosed as liver cirrhosis with jaundice was treated with 'Sibimiguanjung-tang gamibang' and then his symptoms and Liver function improved. 2. Methods We dignosed the patient as Soeumin-Taeum syndrome. So we treated him with Sibimiguanjung-tang gamibang 3. Results After we treated the patient with Sibimiguanjung-tang gamibang, his symptom and liver function was improved. 4. Conclusions Sibimiguanjung-tang gamibang may have an effect on treatment of jaundice with liver cirrhosis of Soeumin.

• Journal of Yeungnam Medical Science
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• v.26 no.2
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• pp.125-129
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• 2009

Colchicine is an alkaloid that has been used for treating acute gouty arthritis, psoriasis, scleroderma and Behcet's syndrome. Colchicine decreased liver fibrosis in rats with carbon tetrachloride induced cirrhosis and in patients with many liver diseases. Therapeutic oral doses of colchicine may cause nausea, vomiting, abdominal pain and diarrhea. The adverse effect of colchicine associated with the dose is bone marrow suppression, and especially neutopenia. Neutropenia has often been reported in patients have taken an overdose of colchicine. We describe a 64-year-old female liver cirrhosis patient with neutropenia that was induced by a therapeutic dose of colchicine.

• Korean Journal of Adult Nursing
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• v.13 no.3
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• pp.476-485
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• 2001

The purpose of this study was to identify the effect of structured information provided on knowledge and self-care behavior. The subjects of this study were both hospitalized patients and outpatients in K university hospital. The instrument use for this study were the knowledge assessment tool and self-care behavior assessment tool by Eom Soon-Ja(1998) and they were modified for liver cirrhosis patients. The data were analyzed by t-test, Chi-square test, Pearson correlation coefficients using SAS program. The results of this study were as follows. The experimental group which had received structured information provided showed greater increased knowledge of liver cirrhosis(P=.001). The experimental group which had received the structured information provided indicated increased self-care performance rate, especially after information about diet(P=.001), activity and bed rest(P=.001), drug therapy and visiting the hospital(P=.001), prevention of a complication and observation(P=.001). In conclusion, structured information provided showed increased in the degree of knowledge and self-care behavior, so information showing is an effective nursing intervention. It is much needed to employ information showing for chronic patients.