• 제목/요약/키워드: Circulation control

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Porcine epidemic diarrhea virus: an update overview of virus epidemiology, vaccines, and control strategies in South Korea

  • Guehwan Jang;Duri Lee;Sangjune Shin;Jeonggyo Lim;Hokeun Won;Youngjoon Eo;Cheol-Ho Kim;Changhee Lee
    • Journal of Veterinary Science
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    • v.24 no.4
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    • pp.58.1-58.25
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    • 2023
  • Porcine epidemic diarrhea virus (PEDV) has posed significant financial threats to the domestic pig industry over the last three decades in South Korea. PEDV infection will mostly result in endemic persistence in the affected farrow-to-finish (FTF) herds, leading to endemic porcine epidemic diarrhea (PED) followed by year-round recurrent outbreaks. This review aims to encourage collaboration among swine producers, veterinarians, and researchers to offer answers that strengthen our understanding of PEDV in efforts to prevent and control endemic PED and to prepare for the next epidemics or pandemics. We found that collaboratively implementing a PED risk assessment and customized four-pillar-based control measures is vital to interrupt the chain of endemic PED in affected herds: the former can identify on-farm risk factors while the latter aims to compensate for or improve weaknesses via herd immunity stabilization and virus elimination. Under endemic PED, long-term virus survival in slurry and asymptomatically infected gilts ("Trojan Pigs") that can transmit the virus to farrowing houses are key challenges for PEDV eradication in FTF farms and highlight the necessity for active monitoring and surveillance of the virus in herds and their environments. This paper underlines the current knowledge of molecular epidemiology and commercially available vaccines, as well as the risk assessment and customized strategies to control PEDV. The intervention measures for stabilizing herd immunity and eliminating virus circulation may be the cornerstone of establishing regional or national PED eradication programs.

Entelon150® (Vitis vinifera Seed Extract) Attenuates Degenerative Changes in Intravascular Valve Prostheses in Rabbits

  • Jue Seong Lee;JungHyeok Seo;Sokho Kim;Md. Mahbubur Rahman;Hong Ju Shin
    • Korean Circulation Journal
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    • v.54 no.1
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    • pp.43-56
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    • 2024
  • Background and Objectives: The therapeutic strategy for inflammation and degenerative calcification is of utmost importance for bioprosthetic heart valve (BHV) implanted patients. The purpose of this study was to compare the anti-inflammatory and anti-calcification effects of Entelon150® (grape seed extract), losartan, and rosuvastatin, in a rabbit model of intravascular BHV leaflet implantation in bovine pericardium. Methods: A total of 28 rabbits were implanted with BHV leaflet in the external jugular veins. The Entelon150® group was administered 7.7 mg/kg Entelon150® twice daily for 6 weeks after surgery. The losartan and rosuvastatin groups received 5.14 mg/kg and 1 mg/kg, respectively, once per day. The control group received 1 ml of saline once daily. And then, calcium concentration was measured in the implanted BHV, and histological and molecular analyses were performed on the surrounding tissues. Results: The calcium content of the implanted tissue in the Entelon150® group (0.013±0.004 mg/g) was lower than that in the control group (0.066±0.039 mg/g) (p=0.008). The losartan (0.024±0.016 mg/g, p=0.032) and rosuvastatin (0.022±0.011 mg/g, p=0.032) groups had lower calcium content than the control group, and higher tendency than the Entelon150® group. Immunohistochemistry revealed that the expressions of bone morphogenic protein 2 (BMP2), S-100, and angiotensin II type 1 receptor in the Entelon150® group showed lower tendency than those in the control group. The protein expression levels of BMP2 were reduced in the Entelon150® group compared with those in the control group. Conclusions: Entelon150® exhibited a significant effect, similar to other drugs, in reducing calcification and inflammation in the intravascular bovine pericardium.

Cooperative Surveillance and Boundary Tracking with Multiple Quadrotor UAVs (복수 쿼드로터 무인기를 이용한 협업 감시 및 경계선 추종)

  • Lee, Hyeon Beom;Moon, Sung Won;Kim, Woo Jin;Kim, Hyoun Jin
    • Journal of Institute of Control, Robotics and Systems
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    • v.19 no.5
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    • pp.423-428
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    • 2013
  • This paper investigates a boundary tracking problem using multiple quadrotor UAVs to detect and track the boundary of physical events. We set the boundary estimation problem as a classification problem of the region in which the physical events occur, and employ SVL (Support Vector Learning). We also demonstrate a velocity vector field which is globally attractive to a desired closed path with circulation at the desired speed and a virtual phase for stabilizing the collective configuration of the multiple quadrotors. Experimental results with multiple quadrotors show that this study provides good performance of the collective boundary tracking.

A Study on the Automatic Sensing Device for Gas Leakage of Cooling Plate Using the Microprocessor System

  • Wang, Jee-Seok;Yoon, Hee-Jong;Kang, Ki-Seong;Kim, Jong-Do
    • Journal of Advanced Marine Engineering and Technology
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    • v.35 no.3
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    • pp.329-334
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    • 2011
  • The cooling water circulation plates had been used to drop the temperature of refractory outside shell of common cooling system by using cooling plate or stave type. When they are attacked by surrounding gas, they are corroded and the water flows in the refractory due to leakage of water. So, the life of refractory material is shortened and changed due to the worse conditions of cooling system. The automatic sensing device for water leakage of cooling plate is developed to check the position of trouble by using the microprocessor system when cooling water leak and gas are flowed into the cooling plate through the leakage position. The flowed gas is detected in the micro-process system which delivers the detected position of cooling plate or stave to main control room through the wireless-radio relay station. This system can be possible to detect the position of cooling plate or stave against the water leakage part immediately and then deliver the signal to main control room by using the microprocessor system and wireless-radio relay station. This system will be developed in changing the working condition from manual system to unmanned auto alarm system.

Operation modes and Protection of VS(Vertical Stabilization) Converter for International Thermonuclear Experimental Reactor (국제 핵융합실험로용 VS(Vertical Stabilization) 컨버터의 운전모드 및 보호동작)

  • Jo, Hyunsik;Jo, Jongmin;Oh, Jong-Seok;Suh, Jae-Hak;Cha, Hanju
    • The Transactions of the Korean Institute of Power Electronics
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    • v.20 no.2
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    • pp.130-136
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    • 2015
  • This study describes the structure and operation modes of vertical stabilization (VS) converter for international thermonuclear experimental reactor (ITER) and proposes a protection method. ITER VS converter supplies voltage (${\pm}1000V$)/current (${\pm}22.5kA$) to superconducting magnets for plasma current vertical stabilization. A four-quadrant operation must be achieved without zero-current discontinuous section. The operation mode of the VS converter is separated in 12-pulse mode, 6-pulse mode and circulation current mode according to the magnitude of the load current. Protection measures, such as bypass and discharge, are proposed for abnormal conditions, such as over current, over voltage, short circuit, and voltage sag. VS converter output voltage is controlled to satisfy voltage response time within 20 msec. Bypass operation is completed within 60 msec and discharge operation is performed successfully. The feasibility of the proposed control algorithm and protection measure is verified by assembling a real controller and implementing a power system including the VS converter in RTDS for a hardware-in-loop (HIL) facility.

A Study for Improvement of Lift Performance of a Horn-type Rudder with the Coanda Effect (콴다 효과를 이용한 혼-타의 양력성능 개선에 관한 연구)

  • Seo, Dae-Won;Oh, Jung-Keun;Lee, Seung-Hee
    • Journal of the Society of Naval Architects of Korea
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    • v.47 no.4
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    • pp.543-552
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    • 2010
  • The Coanda effect is noticeable when a jet stream is applied tangential to a curved surface since then the jet stream remains attached to the surface beyond the point where flow separates otherwise and results in augmentation of circulation and lift. Numerous experimental and numerical studies have been performed in various fields of aerodynamics to exploit the Coanda effect and many of them found to be useful. It can be speculated that the Coanda effect may have practical application to the field of marine hydrodynamics as well since various control surfaces are being used to control behaviors of ships and offshore structures. In the present study, the Coanda effect has been applied to a horn type rudder and a series of numerical computations and model experiments are performed to find the practical applicability. The results indicate that the Coanda jet increases the lift coefficient of the rudder as much as 52% at the momentum coefficient $C_j$ = 0.1 and the rudder angle ${\alpha}=10^{\circ}$.

Real-time Blood Pressure Monitoring in Porcine Tibial Artery Using LC Resonant Pressure Sensor (LC 공진형 압력 센서를 이용한 돼지 경골 동맥의 실시간 혈압 측정)

  • Choi, Won-Seok;Kim, Jin-Tae;Joung, Yeun-Ho
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.25 no.6
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    • pp.445-450
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    • 2012
  • We have developed an implantable wireless sensor for real time pressure monitoring of blood circulation system. MEMS (micro-electro-mechanical system) technology was adopted as a sensor development method. The sensor is composed of photolithographically patterned inductors and a distributed capacitor in gap between the inductors. A resulting LC resonant system produces its resonant frequency in range of 269 to 284 MHz at 740 mmHg. To read the resonant frequency changed by blood pressure variation, we developed a custom readout system based on a network analyzer functionality. The bench-top testing of the pressure sensors showed good mechanical and electrical functionality. A sensor was implanted into tibial artery of farm pig, and interrogated wirelessly with accurate readings of blood pressure. After 45 days, the sensor's electrical response and histopathology were studied with good frequency reading and biocompatibility.

The design and implementation of security kernel assured trusted path (신뢰경로가 보장되는 보안커널 설계 및 구현)

  • 이해균;김재명;조인준
    • Proceedings of the Korea Institutes of Information Security and Cryptology Conference
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    • 2001.11a
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    • pp.340-347
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    • 2001
  • Security operating system applied to MAC(Mandatory Access Control) or to MLS(Multi Level Security) gives both subject and object both Security Level and value of Category, and it restrict access to object from subject. But it violates Security policy of system and could be a circulated course of illegal information. This is correctly IPC(Interprocess Communication)mechanism and Covert Channel. In this thesis, I tried to design and implementation as OS kernel in order not only to give confidence of information circulation in the Security system, but also to defend from Covert Channel by Storage and IPC mechanism used as a circulated course of illegal information. For removing a illegal information flow by IPC mechanism. I applied IPC mechanism to MLS Security policy, and I made Storage Covert Channel analyze system call Spec. and than distinguish Storage Covert Channel. By appling auditing and delaying, I dealt with making low bandwidth.

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Hypocholesterolemic Effect of Indigenous Dadih Lactic Acid Bacteria by Deconjugation of Bile Salts

  • Pato, Usman;Surono, Ingrid S.;Koesnandar, Koesnandar;Hosono, Akiyoshi
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.12
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    • pp.1741-1745
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    • 2004
  • Administration of milk and fermented milks produced from indigenous dadih lactic acid bacteria on serum lipids and bile acids, fecal bile acids and microflora was estimated in hypercholesterolemic rats. Anaerobic lactic acid bacteria decreased and coliforms increased in the feces of the control group; however, the number of fecal lactic acid bacteria remained unchanged when rats were administered milk and fermented milks. Only fermented milk made from Lc. lactis subsp. lactis IS-10285 significantly reduced serum total cholesterol, LDL cholesterol and total bile acids. Milk and fermented milks did not influence the HDL cholesterol. Triglyceride and phospholipid levels were significantly lower in the rats fed fermented milk of Lc. lactis subsp. lactis IS-10285 than rats fed milk and fermented milk of Lc. lactis subsp. lactis IS-29862, but not significantly different from the control group. Hypocholesterolemic effect of Lc. lactis subsp. lactis IS-10285 was attributed to its ability to suppress the reabsorption of bile acids into the enterohepatic circulation and to enhance the excretion of bile acids in feces of hypercholesterolemic rats.

The Effects of Kinesiotaping Applied onto Erector Spinae and Sacroiliac Joint on Lumbar Flexibility

  • Shin, Do-Yun;Heo, Ju-Young
    • The Journal of Korean Physical Therapy
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    • v.29 no.6
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    • pp.307-315
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    • 2017
  • Purpose: The purpose of this study was to investigate the effects of kinesio taping on lumbar flexibility onto erector spinae and sacroiliac joint. Methods: Sixty healthy adults (male=36, female=24) participated in this study and were randomly assigned to the experimental group that received kinesio taping onto erector spinae and sacroiliac joint (n=30) or the control group that received X-letter placebo taping onto them (n=30). Lumbar flexibility (flexion, extension, lateral flexion, and rotation) was measured using back range-of-motion instrument (BROM) II before and after taping. Results: In the change of lumbar flexibility after taping in the experimental group, there were statistically significant difference in flexion, lateral flexion, and rotation (p<0.05), but there was no significant difference in extension. There was no significant difference in the change of lumbar flexibility after taping in the control group. Conclusion: In conclusion, kinesio taping onto erector spinae and sacroiliac joint improved the joint function. Kinesio taping may reduce the muscle tension and facilitate the circulation of tissue fluid. In light of these results, it is thought that the application of kinesio taping had influence on an increase in lumbar flexibility. Therefore, kinesio taping will be able to be used as the method of the prevention of pain and the treatment in the lumbar region.