• Title/Summary/Keyword: Chung-Sup Yoon

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A review of recent evidence of dietary protein intake and health

  • Park, Yoon Jung;Chung, Sangwon;Hwang, Jin-Taek;Shon, Jinyoung;Kim, Eunjung
    • Nutrition Research and Practice
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    • v.16 no.sup1
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    • pp.37-46
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    • 2022
  • The Korea National Health and Nutrition Examination Survey of 2013 to 2017 reported that the average protein consumption of the Korean population is above the current recommended nutrient intake of protein proposed by the Dietary Reference Intakes for Koreans. Some health professionals and the media often advise consuming diets high in protein for promoting metabolic regulation, weight control, and muscle synthesis. However, due to lack of scientific evidence, the validity and safety of high protein consumption are yet to be fully ascertained. The present review assesses recent evidence published in 2014-2020 from human studies, focusing on adequate protein intake and protein sources for the prevention of chronic diseases, particularly metabolic disorders and sarcopenia.

Painterly rendering using density of edges (에지 밀도 정보를 이용한 회화적 렌더링)

  • Lee, Ho-Chang;Park, Young-Sup;Seo, Sang-Hyun;Yoon, Kyung-Hyn
    • Journal of the Korea Computer Graphics Society
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    • v.12 no.4
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    • pp.7-15
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    • 2006
  • The ultimate objective of painterly rendering is to express an inputted image as if it is hand drawn. The factors to express this painterly effect are thickness of the brush, direction, texture and the establishment of criteria judging if the produced brush will be drawn on to the canvas. In this paper, the algorithm using density of the edges in determining the criteria whether the brush will be drawn onto the canvas is proposed. Density of edges refers to the quantity of edge in the specific area. And uses the method of finding the location of the brush to be drawn as a unit of dynamic grid as well as expressing consistent directional through direction interpolation. Also, the texture is expressed using various textured brushes. Considering density of edges,We can express detailed area and abstract area. And it result in more human effect of oil painting.

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The Growth Characteristics of Angelica gigas Nakai according to Cultivation Regions (재배지별 참당귀의 생육특성)

  • Hong Woo Park;Hyun-Jun Kim;Ki Yoon Kim;Dae Hui Jeong;Chung Ryul Jung;Yurry Um;Kwon Seok Jeon
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2020.08a
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    • pp.99-99
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    • 2020
  • 참당귀(Angelica gigas Nakai)는 중국의 동북부지역, 일본 및 한반도 전역에 자생하고 있으며, 예로부터 보혈, 활혈지통, 윤장등의 효능으로 심신혈허, 월경불순, 통경경폐 등의 병증에 주로 사용되었고, 8월부터 뿌리가 급격히 비대하여 10월 말에서 11월 초에 수확을 한다. 본 연구는 참당귀의 주산지인 봉화, 평창을 비롯한 영양, 인제 등 4지역을 선정하여 미세기상장비를 설치 및 토양의 이화학성 분석을 통해 지역별 생육환경을 측정하였고, 또한 참당귀의 생육특성을 조사하였다. 그 결과 5월에서 10월까지 평균 대기온도와 일사량은 인제지역에서 다른지역에 비해 비교적 높은 경향을 나타냈다. 또한 토양온도는 5월에서 8월까지는 영양지역이, 9월과 10월은 봉화지역이 다른지역에 비해 비교적 높은 것으로 조사되었다. 지역별 토양 성분의 이화학적 특성은 봉화지역이 유기물(5.17%), 전질소(0.19%), 유효인산(2187.76mg/kg), 칼륨(1.53cmol+/kg)의 함량이 다른 지역에 비해 높은 경향으로 확인되었고, 인제지역이 칼슘(12.63 cmol+/kg), 마그네슘(3.7cmol+/kg)등 미량원소의 함량이 높은 것으로 분석되었다. pH는 지역별 차이가 확인되지 않았으며, 영양지역의 토성이 사질식양토로 배수성의 차이는 확인되었다. 이에 따른 참당귀의 생육특성은 초장과 줄기직경은 영양지역에서 각각 70.95cm와 35.72mm로 가장 높게 측정되었으며, 잎 길이및 너비는 평창지역에서 각각 42.84cm, 52.39cm로 가장 높게 측정되었다. 뿌리직경은 영양에서 50.49mm, 뿌리길이는 봉화에서 38.05cm, 생중량은 평창에서 328.23g으로 다른지역에 비해 높은 경향을 나타냈다. 상기 결과를 바탕 재배환경과 생장량간의 상관관계를 분석하였다. 재배환경 중 대기 및 토양온도, 대기 습도는 실험이 수행되어진 전 지역에서 이상고온이나 저온과 같은 특이점 없이 비슷한 양상으로 측정되었고, 이에 따라 참당귀생장에 대해 유의한 상관관계가 분석되지 않았다. 토양습도는 지상부(초장, 줄기직경, 잎길이, 잎너비)의 생육과 음의 상관관계에 있다고 사료되나 유의성이 검증되지 않았다.

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Evaluation of HalcyonTM Fast kV CBCT effectiveness in radiation therapy in cervical cancer patients of childbearing age who performed ovarian transposition (난소전위술을 시행한 가임기 여성의 자궁경부암 방사선치료 시 난소선량 감소를 위한 HalcyonTM Fast kV CBCT의 유용성 평가 : Phantom study)

  • Lee Sung Jae;Shin Chung Hun;Choi So Young;Lee Dong Hyeong;Yoo Soon Mi;Song Heung Gwon;Yoon In Ha
    • The Journal of Korean Society for Radiation Therapy
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    • v.34
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    • pp.73-82
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    • 2022
  • Purpose: The purpose of this study is to evaluate the effectiveness of reducing the absorbed dose to the ovaries and the quality of the CBCT image when using the HalcyonTM Fast kV CBCT of cervical cancer patients of child-bearing age who performed ovarian transposition Materials and Methods : Contouring of the cervix and ovaries required for measurement was performed on the computed tomography images of the human phantom (Alderson Rando Phantom, USA), and three Optically Stimulated Luminescence Dosimeter(OSLD) were attached to the selected organ cross-section, respectively. In order to measure the absorbed dose to the cervix and ovaries in the TruebeamTM pelvis mode (Hereinafter referred to as TP), The HalcyonTM Pelvis mode (Hereinafter referred to as HP) and The HalcyonTM Pelvis Fast mode (Hereinafter referred to as HPF), An image was taken with a scan range of 17.5 cm and also taken an image that reduced the Scan range to 12.5cm. A total of 10 cumulative doses were summed, It was replaced with a value of 23 Fx, the number of cervical cancer treatments, and compared In additon, uniformity, low contrast visibility, spatial resolution, and geometric distortion were compared and analyzed using Catphan 504 phantom to compare CBCT image quality between equipment. Each factor was repeatedly measured three times, and the average value was obtained by analysing with the Doselab (Mobius Medical Systems, LP. Versions: 6.8) program. Results: As a result of measuring absorbed dose by CBCT with OSLD, TP and HP did not obtain significant results under the same conditions. The mode showing the greatest reduction value was HPF versus TP. In HPF, the absorbed dose was reduced by 39.8% in the cervix and 19.8% in the ovary compared to the TP in the scan range of 17.5 cm. the scan range was reduced to 12.5 cm, absorbed dose was reduced by 34.2% in the cervix and 50.5% in the ovary. In addition, result of evaluating the quality of the image used in the above experiment, it complied with the equipment manufacturer's standards with Geometric Distortion within 1mm (SBRT standard), Uniformity HU, LCV within 2.0%, Spatial Resolution more than 3 lp/mm. Conclusion: According to the results of this experiment, HalcyonTM can select more various conditions than TruebeamTM in treatment of fertility woman who have undergone ovarian Transposition , because it is important to reduce the radiation dose by CBCT during radiation therapy. So finally we recommend HalcyonTM Fast kV CBCT which maintains image quality even at low mAs. However, it is consider that the additional exposure to low doses can be reduced by controlling the imaging range for patients who have undergone ovarian transposition in other treatment machines.

Growth and Useful Component of Angelica gigas Nakai under High Temperature Stress (고온 스트레스에 따른 참당귀의 생육 및 유용성분 특성)

  • Jeong, Dae Hui;Kim, Ki Yoon;Park, Sung Hyuk;Jung, Chung Ryul;Jeon, Kwon Seok;Park, Hong Woo
    • Korean Journal of Plant Resources
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    • v.34 no.4
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    • pp.287-296
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    • 2021
  • Recently, the pace of global climate change has tremendously increased, causing extreme damage to crop production. Here, we aimed to examine the growth characteristics and useful components of Angelica gigas under extreme heat stress, providing fundamental data for its efficient cultivation. Plants were exposed to various experimental temperatures (28℃, 34℃, and 40℃), and their growth characteristics and content of useful components were analyzed. At the experimental site, the ambient and soil temperature were 19.38℃ and 21.34℃, ambient and soil humidity were 81.3 % and 0.18 m3/m3, solar radiation was 162.05 W/m2. Moreover, the soil was sandy-clay-loam (pH 6.65), with 2.66% organic matter, 868.52 mg/kg soil available phosphate, and 0.14% nitrogen. Values of most growth characteristics, including the survival rate (85%), plant height (38.66cm), and fresh and dry weight (41.3 g and 14.24 g), were the highest at 28℃. Although the highest content of useful components was observed at 34℃ (3.24%), there were no significant differences across temperatures. Growth characteristics varied across temperatures due to detrimental effects of heat stress, such as accelerated tissue aging, reduced photosynthesis, and delay of growth. Similar content of useful components across temperatures may be due to poor accumulation of anabolic products caused by impaired growth at extremely high temperatures.

Evaluation of Nanoscale Zero-valent Iron for Reductive Degradation of Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX): Batch and Column Scale Studies (Hexahydro-1,3,5-trinitro-1,3,5-triazine(RDX)의 환원적 분해를 위한나노영가철의 성능평가: 회분식 및 칼럼 실험)

  • Lee, Chung-Seop;Oh, Da-Som;Cho, Sung-Heui;Lee, Jin-Wook;Chang, Yoon-Seok
    • Journal of Soil and Groundwater Environment
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    • v.20 no.6
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    • pp.117-126
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    • 2015
  • Reductive degradation of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) by nanoscale zero-valent iron (nZVI) was investigated to evaluate the feasibility of using it for in-situ groundwater remediation. Batch experiments were conducted to quantify the kinetics and efficiency of RDX removal by nZVI, and to determine the effects of pH, dissolved oxygen (DO), and ionic strength on this process. Experimental results showed that the reduction of RDX by nZVI followed pseudo-first order kinetics with the observed rate constant (kobs) in the range of 0.0056-0.0192 min−1. Column tests were conducted to quantify the removal of RDX by nZVI under real groundwater conditions and evaluate the potential efficacy of nZVI for this purpose in real conditions. In column experiment, RDX removal capacity of nZVI was determined to be 82,500 mg/kg nZVI. pH, oxidation-reduction potential (ORP), and DO concentration varied significantly during the column experiments; the occurrence of these changes suggests that monitoring these quantities may be useful in evaluation of the reactivity of nZVI, because the most critical mechanisms for RDX removal are based on the chemical reduction reactions. These results revealed that nZVI can significantly degrade RDX and that use of nZVI could be an effective method for in-situ remediation of RDX-contaminated groundwater.

Studies on Pharmacokinetics of a new NSAID SJ-151(I)

  • Kim, Dong-Sup;Chung, Hye-Joo;Na, Han-Kwang;Park, Yoon-Ju;In Sook, Park;Ahn, Mi-Lyung;Chang, Young-Sup
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1996.04a
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    • pp.220-220
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    • 1996
  • The objectives of this study were to evaluate the pharmacokinetics of SJ-151 which is a new NSAID in male Beagle dogs following a single oral dosing. Seven beagle dogs (10-l2kg) were all administered a single oral gavage(10mg/kg) of SJ-151 tablet and serial blood samples of approximately 5$m\ell$ were then drawn from the cephalic vein of each animal at 0(predose), 0.25, 0.5, 1, 1.5, 2, 3, 4, 6, 8, 12 and 24hours postdosc. SJ-151 (Cinmetacinㆍbutendiol)and cimetacin were quantified in the plasma fraction by HPLC assay. The pharmacokinetic parameters calculated from the plasma concentrations of SJ-151 in dayl are Cmax(ng/$m\ell$)509$\pm$248, Tmax(hr) 1.50$\pm$0.45, AUC(ng.hr/$m\ell$) 1,750$\pm$762, tl/2$\alpha$ 0.98$\pm$0.30, t1/2$\beta$ 12.0$\pm$6.75. The pharmacokinetic parameters calculated from the plasma concentrations of Cinmetacin in day 1 are Cmax(ng/$m\ell$)258$\pm$74.1, Tmax(hr)2.42$\pm$ 0.92, AUC(ng.hr/$m\ell$) 1,820$\pm$318, t1/2$\alpha$ 1.74$\pm$0.49, t1/2$\beta$ 25.4$\pm$13.4.

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Synthesis and Lubricant Properties of Vegetable Oil based on Estolides (식물유 기반 에스토라이드 합성 및 윤활 특성)

  • Son, Jeong-Mae;Kim, Nam-Kyun;Shin, Jihoon;Chung, Kunwo;Yoon, Byung-Tae;Kim, Young-Wun
    • Tribology and Lubricants
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    • v.31 no.5
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    • pp.195-204
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    • 2015
  • Several researches are focused on improving the value of fine chemicals based on biomass resources due to environmental and other concerns associated with the use of petroleum-based products. Therefore, the synthesis and application of estolides derived from plant-based waste oil materials and their application as lubricants and as processing oil for butyl rubber products have been studied. Four kinds of estolide were prepared with conversions of 71~92% over 24h using various vegetable oils, as determined by size exclusion chromatography (SEC) and nuclear magnetic resonance (NMR) spectroscopy. FT-IR spectroscopy determines the esterification of estolides using 2-ethylhexyl alcohol. The estolides have iodine values of 35~90, α-ester/α-acid ratios of 0.45~0.55, and total acid number of 114~134 mg KOH g–1. Four ball wear tests show that the wear scar diameters (WSDs) of estolides as base oil significantly decreased to 0.328~0.494 mm, compared to WSDs of 0.735 and 0.810 mm of WSD for 150N and Yubase 6, respectively, as general base oil. Thus, the estolides have better wear resistance and satisfying design objectives for the engineering of a variety of lubricant base oils.

Radical Scavenging Activities of Tannin Extracted from Amaranth (Amaranthus caudatus L.)

  • Jo, Hyeon-Ju;Chung, Kang-Hyun;Yoon, Jin A;Lee, Kwon-Jai;Song, Byeong Chun;An, Jeung Hee
    • Journal of Microbiology and Biotechnology
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    • v.25 no.6
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    • pp.795-802
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    • 2015
  • This study investigates the bioactivity of tannin from amaranth (Amaranthus caudatus L.) extracts. The antioxidant activities of the extracts from amaranth leaves, flowers, and seeds were evaluated. Tannin from leaves of amaranth has been evaluated for superoxide scavenging activity by using DPPH and ABTS+ analysis, reducing power, protective effect against H2O2-induced oxidative damage in L-132 and BNL-CL2 cells, and inhibition of superoxide radical effects on HL-60 cells. At a concentration of 100 µg/ml, tannin showed protective effects and restored cell survival to 69.2% and 41.8% for L-132 and BNL-CL2 cells, respectively. Furthermore, at the same concentration, tannin inhibited 41% of the activity of the superoxide radical on HL-60 cells and 43.4% of the increase in nitric oxide levels in RAW 264.7 cells. The expression levels of the antioxidant-associated protein SOD-1 were significantly increased in a concentration-dependent manner in RAW 264.7 cells treated with tannin from amaranth leaves. These results suggest that tannin from the leaves of Amaranthus caudatus L. is a promising source of antioxidant component that can be used as a food preservative or nutraceutical.

Efficient Micropropagation of Pear Germplasm Using Soot Tips and Nodal Explants

  • Yi, JungYoon;Lee, GiAn;Chung, JongWook;Lee, YoungYi;Gwag, JaeGyun;Lee, SeokYoung
    • Korean Journal of Plant Resources
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    • v.28 no.6
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    • pp.690-696
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    • 2015
  • We micropropagated pear (Pyrus species) using shoot tips and nodal explants from three pear genotypes. The ability to establish shoot tip cultures, proliferate shoots, induce rooting, and acclimatize the resulting plantlets are all elements of in vitro micropropagation. Shoots were induced from shoot tips on Murashige and Skoog medium (MS) with five different plant growth regulator combinations. The highest shoot formation rates were achieved for the three genotypes using MS supplemented with 1.0 mg/L N6-benzyladenine (BA) and 0.1 mg/L gibberellic acid (GA3). The maximum shoot number and shoot length for the three cultivars were recorded with 2.0 mg/L BA and 0.2 mg/L indole-3-butyric acid (IBA) in multiplication medium using nodal explants produced from microshoots. Nodal explants with one or two axillary buds cultured for three weeks initiated roots on medium supplemented with various concentrations of 1-naphthaleneacetic acid (NAA) or/and IBA in half-strength MS medium for adventitious rooting. The highest rooting response was with the combination of 0.2 mg/L NAA and 0.2 mg/L IBA. A combination of NAA and IBA resulted in a significant increase in the rooting ratio over NAA or IBA alone. In this medium, the root formation rate according to ranged from 68.9% for the BaeYun No. 3 genotype to 51.8% for the Hwanggeum genotype. We also investigated the influence of the concentration the polyamine phloroglucinol in rooting medium. For all three genotypes, the highest rooting ratio, longest root length, and greatest root number were observed in the treatments with 75-150 mg/L phloroglucinol. Most rooted plants were acclimatized successfully.