• The Transactions of The Korean Institute of Electrical Engineers
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• v.59 no.6
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• pp.1131-1135
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• 2010

The development of modern civilization result from the abundance of material. Yet modern people live with chronic mild stress. Excessive chronic mild stress leads to various diseases. From the risk of the disease in order to protect our bodies need to manage chronic mild stress. The purpose of this study is to inspection the effectiveness of detecting in chronic mild stress using the Multi-sensor system. The Multi-sensor system is designed that can be measure three kinds of vital signals of chronic mild stress for the detection. First Photoplethysmogram(PPG), second Electro Dermal Activity(EDA), third Skin Temperature(SKT). The ages and occupations exposed to chronic mild stress, people often use out of this system was applied to dairy products(Pen). In addition, vital signals that occur when the variety of noise was used to remove the accelerometer. Chronic mild stress by the analysis of measured vital signals from Multi-sensor system to the measurement information to a PC to a wireless transmission(Bluetooth). In this study, using Multi-sensor system writing conditions and a variety of situations in the movement to measure vital signals and measurement results verified the accuracy and reliability. Through this measure chronic mild stress in everyday life and managing to maintain will help more healthy lifestyle.

• Journal of Korean Academy of Nursing
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• v.33 no.1
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• pp.87-94
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• 2003

Purpose: The purpose of this study was to identify the factors influencing Symptoms of Stress in patients with chronic illness. Method: Data were collected by questionnaires from 1,748 patients with chronic disease in General Hospital in Seoul. Chronic diseases of were cardiac disease including hypertension, peptic ulcer, pulmonary disease included COPD and asthma, DM, and chronic kidney disease. The data were analyzed using descriptive statistics, pearson correlation coefficients, and stepwise multiple regression. Result: 1. The level of symptoms of stress was moderate(M=2.17). 2. The score of symptoms of stress showed significantly positive correlation with the score of mood state(r=.58, p=.00), perceived stress(r=.57, p=.00), and ways of coping(r=.33, p=.00). The symptoms of stress showed significantly negative correlation with the score of social support(r=-.37, p=.00) and self-esteem(r=-.19, p=.00). 3. The most powerful predictor of symptoms of stress was mood state and the variance explained was 34%. A combination of mood state, ways of coping, perceived stress, social support, and duration of illness account for 45% of the variance in symptoms of stress of the patients with chronic illness. Conclusion: This study suggest that mood state, ways of coping, perceived stress, and social support are significantly influencing factors on symptoms of stress of the patients with chronic illness.

• The Korean Journal of Physiology and Pharmacology
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• v.18 no.3
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• pp.263-268
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• 2014

The etiology of most psychiatric disorders is still incompletely understood. However, growing evidence suggests that stress is a potent environmental risk factor for depression and anxiety. In rodents, various stress paradigms have been developed, but psychosocial stress paradigms have received more attention than non-social stress paradigms because psychosocial stress is more prevalent in humans. Interestingly, some recent studies suggest that chronic psychosocial stress and social isolation affects mainly anxiety-related behaviors in mice. However, it is unclear whether chronic non-social stress induces both depression- and anxiety-related phenotypes or induces one specific phenotype in mice. In the present study, we examined the behavioral consequences of three chronic non-social stress paradigms: chronic predictable (restraint) stress (CPS), chronic unpredictable stress (CUS), and repeated corticosterone-HBC complex injection (RCI). Each of the three paradigms induced mild to severe depression/despair-like behaviors in mice and resulted in increased immobility in a tail suspension test. However, anxiety-related phenotypes, thigmotaxis and explorative behaviors, were not changed by the three paradigms. These results suggest that depression- and anxiety-related phenotypes can be dissociated in mouse stress models and that social and non-social stressors might affect brain circuits and behaviors differently.

• BMB Reports
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• v.48 no.4
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• pp.209-216
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• 2015

Stress is now recognized as a universal premorbid factor associated with many risk factors of various chronic diseases. Acute stress may induce an individual's adaptive response to environmental demands. However, chronic, excessive stress causes cumulative negative impacts on health outcomes through "allostatic load". Thus, monitoring the quantified levels of long-term stress mediators would provide a timely opportunity for prevention or earlier intervention of stressrelated chronic illnesses. Although either acute or chronic stress could be quantified through measurement of changes in physiological parameters such as heart rate, blood pressure, and levels of various metabolic hormones, it is still elusive to interpret whether the changes in circulating levels of stress mediators such as cortisol can reflect the acute, chronic, or diurnal variations. Both serum and salivary cortisol levels reveal acute changes at a single point in time, but the overall long-term systemic cortisol exposure is difficult to evaluate due to circadian variations and its protein-binding capacity. Scalp hair has a fairy predictable growth rate of approximately 1 cm/month, and the most 1 cm segment approximates the last month's cortisol production as the mean value. The analysis of cortisol in hair is a highly promising technique for the retrospective assessment of chronic stress. [BMB Reports 2015; 48(4): 209-216]

• Korean Journal of Pharmacognosy
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• v.42 no.1
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• pp.32-37
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• 2011

The effects of herbal ethanol extract from Gynostemma pentaphyllum (GP extract) on chronic stress-induced anxiety in mice were investigated. The animals were treated with GP extracts (50 and 100 mg/kg/day, p.o.) for 21 days before exposure to electric footshock (EF; duration and interval 10 sec for 3 min, 2 mA) for chronic stress once a day. The ambulatory locomotor activity was reduced by chronic EF stress and it was recovered by 12.9-15.1% in GP extract-treated groups. The grip strength was also significantly decreased by chronic EF stress, however, the EF-stressed groups treated with GP extract increased grip strength from 13.9% to 56.8% compared to EF-stressed groups. In addition, the serum levels of corticosterone were significantly elevated by chronic EF stress to 197% of the control levels, which was reduced to 73.1% by treatment with GP extract (100 mg/kg). In contrast, the brain levels of dopamine and serotonin were reduced to 67.6% and 63.1% by chronic EF stress, which was recovered to 90% of the control levels by treatment with GP extract. These results indicate that GP extract shows the ameliorating effects on chronic EF stress-induced anxiety in mice and it can be developed as the promising anti-anxiety agent.

• Nutrition Research and Practice
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• v.11 no.1
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• pp.25-32
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• 2017

BACKGROUND/OBJECTIVES: Stress-induced cognitive impairment is related to the suppression of hippocampal neurogenesis that results from an increase of oxidative stress. Therefore, the aim of this study was to investigate the effects of administration of a blueberry drink, having a high antioxidant power, on the cognitive performance of adult rats exposed to chronic mild stress. MATERIALS/METHODS: Twelve-week-old male Sprague-Dawley rats (n = 48) were randomly divided into four groups: control (CO), stress (ST), control + 5% blueberry drink (CO + B), and stress + 5% blueberry drink (ST + B). After eight weeks, the cognitive performance was assessed using a multiple T-maze water test. Levels of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and ascorbic acid were measured in the brain, and catecholamine concentrations were measured in plasma. RESULTS: The brain weights of the rats from the ST and ST + B groups were significantly lower than those of the rats from the CO and CO + B groups. The cognitive performance of the ST group was impaired when compared to that of the CO group. This impairment was significantly improved by the blueberry drink supplementation (P < 0.05). The brain SOD and CAT concentrations were not influenced by the stress or by the blueberry drink. However, the brain levels of GPx and ascorbic acid were significantly lower in the ST group than those in the CO group and were increased by the blueberry drink supplementation. The plasma catecholamine concentrations were affected by chronic mild stress and by the blueberry drink. The plasma norepinephrine and dopamine concentrations were decreased by the chronic stress and improved by the blueberry drink supplementation. The plasma epinephrine level was only influenced by the stress. CONCLUSION: These findings suggest that the blueberry drink may protect against the cognitive impairment induced by chronic mild stress.

• Human Ecology Research
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• v.57 no.2
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• pp.201-211
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• 2019

This study examines the effects of chronic disease/disability and stress from health on depressive symptoms among one-person households living in Seoul and Gyeonggi Province in Korea. This study also investigates the moderating effect of social support on the relationship between 1)having a chronic disease/disability and depressive symptoms as well as 2)stress from health and depressive symptoms. This study used data from an online survey targeting one-person households living in Seoul and Gyeonggi Province. The final sample included 499 one-person households. Using a multiple regression analysis with SPSS 20.0, results showed that having a chronic disease/disability was associated with a higher level of depressive symptoms. In addition, stress from health was associated with a higher level of depressive symptoms. In regard to the roles of social support, economic support and emotional support had a direct negative effect on depressive symptoms. Emotional support had a moderating effect on the relationship between having a chronic disease/disability and depressive symptoms. In addition, emotional support also had a moderating effect on the relationship between stress from health and depressive symptoms. Based on these findings, this study suggests that policy makers should reduce the economic burden from a chronic disease/disability and help one-person households to strengthen their social support network.

• Journal of Digital Convergence
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• v.16 no.1
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• pp.371-379
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• 2018

The purpose of this study was to investigate the effects of maladaptive perfectionism and stress coping on chronic fatigue of adolescent athletes. In order to achieve these purposes, a questionnaire survey was conducted with 254 adolescent athletes. The following conclusions were obtained. 1. In the stress coping and chronic fatigue level by maladaptive perfectionism level, the higher the level of maladaptive perfectionism showed a high level of emotional mitigation coping, wishful thinking seeking and chronic fatigue. 2. The correlation between maladaptive perfectionism, stress coping and chronic fatigue showed a significant level between each sub-factor. 3. The influence that maladaptive perfectionism and stress coping have on chronic fatigue are "anxiety about a mistake", "a doubt about the performance", "emotional mitigation coping" and "wishful thinking seeking". This result suggest importance of dealing with maladaptive perfectionism and stress coping in reduce the chronic fatigue.

• Korean Journal of Psychosomatic Medicine
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• v.3 no.2
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• pp.126-138
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• 1995

For investigating a disease specific psychological mechanism in various dermatological disorders, we tried to explore the difference in correlation among stress perception, locus of control as a coping strategy, depressive symptoms and pruritic symptoms in the patients with psychological pruritis and chronic urticaria. The subjects were composed of 32 patients with psychol-ogical pruritis and 67 patients with chronic urticaria(subject group), and 25 patients with organic pruritis and 59 patient with major depression(control group). Global assesment of recent stress scale(GARS), I-E locus of control scale, Beck Depression Inventory(BDI) and medical college of wisconsin center pain follow up questionnaire were used for assesement. The results were as follows: 1) There were a significant positive correlation between stress perception and depressive symptom in patients with psychological pruritis, chronic urticaria, and major depression but not hi organic pruritis. 2) In relationship between locus of control and depressive symptom, patients with psychological pruritis, organic pruritis, and major depression except chronic ruticaria showed a significant negative correlation. 3) For intensity and pattern of pruritis, there were positive relations with depressive symptom and stress perception only in patients with chronic urticaria. Above results indicate that stress perception and locus of contorl may play a significant role in the formation of psychological and dermatological symptoms in psychological pruitis and chronic urticaria. But the mechanisms of these processes are different in either disorder.

• Journal of Korean Academy of Nursing
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• v.34 no.3
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• pp.586-594
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• 2004

Purpose: The purpose of this study was to identify the factors influencing file-up family stress in the family with a family member having a chronic mental illness. Method: Data was collected by questionnaires from 365 families with a member having a chronic mental illness, in an outpatient clinic of a General Hospital and Government Psychiatric Hospital in Seoul. The data was analyzed using descriptive statistics, pearson correlation coefficients, and stepwise multiple regression. Result: The score of file-up stress showed a significantly negative correlation with the score of level of hardiness (r=-.31, p=.00), family support (r=-.13, p=.00), family cohesion (r=-.25, p=.00), and sense of coherence (r=-.26, p=.00). The most powerful predictor of file-up stress was family hardiness and the variance was 11.1%. Acombination of hardiness, family support, and sense of coherence account for 14.8 % of the variance in file-up stress of the family with a member having a chronic mental illness. Conclusion: This study suggests that family support, hardiness, cohesion, and sense of coherence are significant influencing factors on file-up stress in the family with a member having a chronic mental illness.