• Archives of Pharmacal Research
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• v.26 no.8
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• pp.597-600
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• 2003

Silybin has a potent antibacterial activity, more potent than silymarin II, against gram-positive bacteria without hemolytic activity, whereas it has no antimicrobial activity against gram-negative bacteria or fungi. The mode of action of silybin against the gram-positive bacterial cell was examined by investigating the change in plasma membrane dynamics of bacterial cells using 1 ,6-diphenyl-1,3,5-hextriene (DPH) as a membrane probe and by assessing the inhibition of macromolecular synthesis using radiolabeled incorporation assay. The results showed that silybin inhibited RNA and protein synthesis on gram-positive bacteria.

• Honam Mathematical Journal
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• v.14 no.1
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• pp.37-44
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• 1992

• Proceedings of the Korean Nutrition Society Conference
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• 2003.05a
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• pp.120.2-120.2
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• 2003

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2018.05a
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• pp.188-189
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• 2018

• Proceedings of the PSK Conference
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• 2001.10a
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• pp.227.2-228
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• 2001

• Proceedings of the PSK Conference
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• 2001.04a
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• pp.152.1-152.1
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• 2001

• Proceedings of the PSK Conference
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• 2001.04a
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• pp.153.2-153.2
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• 2001

• Journal of Korean Dental Science
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• v.8 no.1
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• pp.10-15
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• 2015

Purpose: The aim of the present study is to assess the importance of proper treatment timing for dental emergency patients by characterizing current patient care in the emergency room. Materials and Methods: A retrospective chart review of 3,211 patients who visited the Chosun University Hospital's dental emergency department (Gwangju, Korea) was conducted from January 1, 2011 to May 31, 2014. Information regarding age, gender, onset date, main causes, and diagnoses were collected and analyzed. The main causes were divided into six categories: assault, household/play, sports, traffic, work, and others. Result: Emergency visits were more common for men (69%), and the ratio of males to females was 2.2:1 On average, the major cause was household/play (49.8%), followed by others (18.9%), traffic (16.6%), assault (9.1%), sports (2.9%), and work (2.6%). The most frequent diagnosis on average was dental trauma with 82.4%, followed by infection (10.7%), others (4.7%), and bleeding (2.2%). Conclusion: The main reasons for visits to the dental emergency department are dental trauma, dental infection, bleeding, and others. The most frequent reason for dental emergency patients to visit the emergency department was dental trauma (82.4%).

• Journal of the Korean Society of Costume
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• v.53 no.7
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• pp.37-45
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• 2003

This study is to research the changing trends in the trading goods and the cause of the change in the early Chosun dynasty and to find out the influence that the export goods had on the Chosun society. This research demonstrated the costume culture of the early Chosun was affected by the trading trends. The export items of Chosun showed differences in chronological order. They changed from hemp cloth to cotton cloth. The cause of such change in the export items was due to the change in the amount of demand and supply, to products of Chosun. and to social factors. Looking at the amount and items of the export goods to Japan, the amount was huge and the number of trade was a lot. There were several influences that the exporting cotton cloth to Japan had on Chosun's costume culture. First, the export caused the growth of cotton industry through the reinforcement policy. Next, it made the amount of national deposit of cotton cloth exhausted as a result of the increase in the amount of the exporting cotton. It also made worse the dual distribution structure of cotton cloth and the leaning toward bad cotton cloth. And in consequence of the connection between rich merchants and politicians, these social phenomena became worse and worse. And these facts demonstrate that the costume culture of the early Chosun dynasty was affected by the trade between Chosun and Japan. Therefore, to better understand the costume culture of the early Chosun dynasty, I propose to consider the consequences resulted from the trade with Japan.

• International Journal of Oral Biology
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• v.35 no.4
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• pp.191-195
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• 2010

Oleanolic acid is a natural triterpenoid that exists widely in foods and some medicinal herbs. The purpose of this study was to determine the antimicrobial activity of oleanolic acid against Streptococcus mutans strains isolated from a Korean population. Antimicrobial activity against these bacteria was evaluated by minimal inhibitory concentration (MIC) and time kill curves. The tolerance of human gingival fibroblasts and human periodontal ligaments to oleanolic acid was tested using a methyl thiazolyl tetrazolium (MTT) assay. The $MIC_{90}$ value of oleanolic acid for both S. mutans and S. sobrinus isolated from Koreans was 8 ${\mu}g/ml$. Oleanolic acid showed bactericidal effects against S. mutans ATCC $25175^T$ and S. sobrinus ATCC $33478^T$ at $1\;{\times}\;MIC$ ($8{\mu}g/ml$) and had no cytotoxic effects against KB cells at this dose. The results suggest that oleanolic acid could be useful in the future development of oral hygiene products for the prevention of dental caries.