• Journal of Korean Medicine Rehabilitation
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• v.26 no.4
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• pp.23-35
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• 2016

Objectives This systematic review is to support the effectiveness of herbal medicine for the treatment of simple obesity in adults. Methods A total of 8 electronic databases were searched in English, Chinese and Korean. Standard methodologies for the systematic review were used to search, analyze and synthesize data based on NECA's guideline for undertaking systematic review and meta-analyses for intervention. Results After screening 1781 potential articles, we identified 13 randomized controlled trials (RCTs). We conducted a meta-analysis for the study using Bangpungtongsung-san and Taeeumjowi-tang to evaluate the effectiveness of herbal medicines on weight loss compared to placebo control. Both herbs showed positive effect in weight, body mass index and waist circumference. In an analysis comparing herbal effects considering constitutions showed that proper treatment can lower adverse events. Conclusions Our results provide evidence that herbal medicine can be an effective treatment for the obesity compare to placebo or to conventional medicine without serious adverse events. Further study is needed to evaluate effectiveness of herbal medicines considering personalized treatment and its safety.

• Journal of Society of Preventive Korean Medicine
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• v.6 no.2
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• pp.36-47
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• 2002

Over thousands of years oriental traditional medicine has developed a theoretical and practical approach to treat and prevent diseases and to promote people's health in China and Korea. In China, the integration of traditional Chinese medicine into the national healthcare system began in the late 1950s. This was in response to national planning needs to provide comprehensive healthcare services. On contrary to China, South Korea established the parallel operation of two independent medical systems in 1952. Hence there has been a political conflict between oriental and modern medicine over issues of fee, the ability to sell and prescribe herbal medicines, and the licensing of practitioners in traditional medicines. Given this background. This study is to compare peoples' attitudes and opinions for oriental traditional medicine by ethnicity (Chinese, Korean-Chinese and Korean). Chinese and Korean-Chinese were more used and satisfied with traditional medicine treatment and traditional practitioners compared with Koreans. The proportion of Koreans who reported the cost of traditional treatments was expensive was higher than those of Chinese and Korean Chinese. Most of Chinese, Korean-Chinese, and Koreans reported that they would use traditional medicine: 1) when they would have some disease to be treated best through traditional medicine; and 2) when traditional practitioner had a reputation and lots of experiences for those diseases. Most Korean people reported that oriental and western practitioners should cooperate each other to improve the quality of care. Therefore, policy framework including integration of traditional and western medicine, regulation, etc. is needed. In addition, research is needed to determine which diseases is treated best through traditional medicine.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.18 no.8
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• pp.2103-2118
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• 2024

Chinese herbal slices (CHS) automated recognition based on computer vision plays a critical role in the practical application of intelligent Chinese medicine. Due to the complexity and similarity of herbal images, identifying Chinese herbal slices is still a challenging task. Especially, easily-confused CHS have higher inter-class and intra-class complexity and similarity issues, the existing deep learning models are less adaptable to identify them efficiently. To comprehensively address these problems, a novel tiny easily-confused CHS dataset has been built firstly, which includes six pairs of twelve categories with about 2395 samples. Furthermore, we propose a ResNeSt-CHS model that combines multilevel perception fusion (MPF) and perceptive sparse fusion (PSF) blocks for efficiently recognizing easilyconfused CHS images. To verify the superiority of the ResNeSt-CHS and the effectiveness of our dataset, experiments have been employed, validating that the ResNeSt-CHS is optimal for easily-confused CHS recognition, with 2.1% improvement of the original ResNeSt model. Additionally, the results indicate that ResNeSt-CHS is applied on a relatively small-scale dataset yet high accuracy. This model has obtained state-of-the-art easily-confused CHS classification performance, with accuracy of 90.8%, far beyond other models (EfficientNet, Transformer, and ResNeSt, etc) in terms of evaluation criteria.

• CELLMED
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• v.4 no.4
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• pp.28.1-28.27
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• 2014

Linderae Radix, the dry roots of Lindera aggregata (Sims) Kosterm, has long been used as traditional Chinese medicine for treatment of inflammatory diseases. The total alkaloids are believed to be the active components responsible for anti-inflammation of Linderae Radix. Here, the total alkaloids of Linderae Radix were extracted and isolated, including 12 isoquinoline alkaloids and 1 furan sesquiterpene. Within the alkaloids, norisoboldine, boldine, linderaline, isoboldine, reticuline, N-methyllaurotetanine, norjuziphine were found to be the major ingredients. In lipopolysaccharide-treated macrophage RAW 264.7 cells, application of Linderae Radix extract, or total alkaloids, suppressed the transcription of proinflammatory cytokines, interleukin-$1{\beta}$ and interleukin-6. Out of the 12 alkaloids, norisoboldine, boldine, and isoboldine were tested in lipopolysaccharide-treated macrophages, and norisoboldine was the strongest alkaloid in suppressing the cytokine expressions. The current studies suggested that the identification of alkaloids from Linderae Radix could provide a plausible explanation for herbal therapeutic functions.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.32 no.4
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• pp.130-140
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• 2019

Objective : The purpose of this study is to examine the treatment of allergic rhinitis introduced in the Chinese guideline, and to find out the direction of evidence-establishment and applicability in developing Korean Medicine clinical practice guideline for allergic rhinitis. Method : We studied Traditional Chinese Medicine treatment of allergic rhinitis introduced in the 2018 Chinese society of allergy guidelines for diagnosis and treatment of allergic rhinitis. The treatment are classified into three categories; herbal medicines, acupuncture and the others. And we compared this guidelines with other guidelines for how they differ in description of the database, evidence of level, and strength of recommendation. Results : Herbal medicines are presented based on syndrome differentiation. The basic acupoints for allergic rhinitis are introduced as follows; Fengchi(GB20), Yingxiang(LI20), Feishu(BL13) and Taiyuan(LU9). And in comparison with other guidelines for allergic rhinitis, the Chinese guideline showed lack of description in the database, evidence of level, and strength of recommendation, though they used evidence-based models. Conclusions : Clinical practice guideline projects are also underway in Korea for benefit expansion and improving quality of medical services. It is important to develop guidelines which should be evidence-based and reflect Korean medical environment.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.12 no.1
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• pp.13-21
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• 2008

Objectives: To review the history, method, parameters, system of electrogastrography(EGG) and to study its oriental medical application in Traditional Chinese Medicine. Methods: We investigate the research results through internet search engine, CNKI (China National Knowledge Infrastructure). Results: In China, EGG was studied on various regions, including multifarious regions of Traditional Chinese Medical. And also regions of Traditional Chinese Medical could divide classification of diseases, herbal medicine, acupuncture and the like. Conclusions: EGG is a noninvasive, easy and painless method that is kept recordings of the electrical activity of the stomach, therefore it has used for studies and clinics widely. EGG in Traditional Chinese Medicine has used an objective parameter that verified efficacies of oriental medicine. I would therefore like to conclude that there should be continued study and active application of EGG in the wide variety of oriental medicine.

• Korean Journal of Pharmacognosy
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• v.44 no.2
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• pp.200-208
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• 2013

The aim of this study was to evaluate the shelf-life of Bojungikgi-tang (Buzhongyiqi-tang in Chinese) by long-term storage test. Experiments were performed to evaluate the stability such as the selected physicochemical, pH, identification, heavy metal, microbiological experiment, and amount of marker compounds under a long-term storage test of Bojungikgi-tang decoction. The significant change was not showed in pH, heavy metal, microbiological, and identification test based on long-term storage test. Furthermore, the HPLC analysis was performed for the determinations of liquiritin, glycyrrhizin, nodakenin, and hesperidin in Bojungikgi-tang by long-term storage test. We were calculated shelf-life of Bojungikgi-tang decoction based on the amount change of four constituents. Consequently, Shelf-life by four compounds at room temperature was predicted 23 month. The suggested shelf-life would be helpful on the storage and distribution of herbal medicine.

• The Journal of Korean Medicine
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• v.41 no.1
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• pp.107-116
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• 2020

Objectives: To overcome the limitations of randomized controlled trials, many other trials design is tested. The n-of-1 trial is a promising research method in the field of Korean medicine because of this methodology can examine the optimal treatment for each patient strictly. Therefore, we reviewed the status of N-of-1 studies on herbal medicine. Methods: A systematic literature review was conducted based on the pubmed database. The search term were 'N-of-1 Trial', 'Chinese Medicine', 'Herbal Medicine', 'Kampo'. There was no restriction in year. Results: Four clinical trials have been identified to demonstrate the effectiveness of herbal medicines for Kidney-yin-deficiency syndrome, bronchiectasis and gastric cancer. These studies suggest that the N-of-1 design is a study that encourages patient involvement, demonstrates the effectiveness of herbal medicines and helps reduce unnecessary medication. Conclusion: The N-of-1 clinical trial may be a rigorous methodology suitable for the clinical setting and may help the development of evidence-based Korean medicine. Attention is also needed in this research method in Korea.

• Herbal Formula Science
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• v.29 no.4
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• pp.297-310
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• 2021

Objectives : In traditional herbal medicine, as clinical experience increased, the number of herbal formulas also increased. For example, there are 61,739 herbal formulas in Pujifang, and 96,592 in Dictionary of Traditional Chinese Medicine Prescriptions. In chapter of Clear Heat (CH; 淸熱劑) of textbook, the 38 formulas were presented. For enhancing understanding of herbal formula, a large majority of books explained each individual formula with description or figure about interactions between constituent herbs. But there is no study on the interrelationship of each CH herbal formulas. This study investigated the interrelationship of CH herbal formulas. Methods : The CH herbal formula were analyzed with the ingredients, actions and clinical applications by literature study. Results : To improve cognition the interrelationship of CH herbal formulas, we analyzed the formulas and established the 16 interrelations of herbal formulas. Conclusions : Finally, this study established the interrelation of herbal formula as one figure. This result could contribute to improve cognition on the interrelationship of CH herbal formulas.

• The Journal of Korean Medical History
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• v.27 no.1
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• pp.77-86
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• 2014

The paper describes the practice and purpose of the medical missionaries research on the traditional Chinese drugs(中藥). Searches were made using the journal of the China Medical Missionary Association. The China Medical Missionary Association established the committee of the Chinese Materia Medica in 1890. This committee aimed to research on the traditional Chinese drugs. Then why did the medical missionaries study traditional Chinese drugs? This is because the western drugs(西洋藥）was not easy to acquire, especially in land areas. Also, some western drugs have poor quality and expensive. Therefore they need to understand that Chinese drugs will help in the production of the western drugs. But from around 1920, the main purpose of the research was changed. The scientific and systematic investigation on the Chinese medicine itself became more important. And this change partly influenced that medical missionaries' views on traditional Chinese drugs.