• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.14 no.1
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• pp.26-35
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• 2003

Conventional antipsychotics are commonly used to treat children and adolescents suffered from schizophrenia to other neuropsychiatric conditions. Regrettably, studies for typical antipsychotics report high rates of sedation, orthostatic hypotension, and extrapyramidal side effects. Over the past few years, atypical antipsychotics have been prescribed for use in adults with psychotic symptoms. Child psychiatrists have begun using these drugs to children and adolescents hoping safe and better alternatives to the conventional antipsychotics. However, there is not enough short-term and almost no long-term data about atypical antipsychotics for pediatric patients. Therefore, the purpose of this article is to review what is known about the use of the atypical antipsychotics in young patients. To do so, an appropriate approach to the use of these drugs in child and adolescent patients my be offered.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.32 no.3
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• pp.93-98
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• 2021

Electroencephalography (EEG) measures neural activation due to various cognitive processes. EEG and event-related potentials (ERPs) are widely used in studies investigating psychopathology and neural substrates of psychiatric diseases in children and adolescents. The present study aimed to review recent ERP studies in child and adolescent psychiatry. ERPs are non-invasive methods for studying synaptic functions in the brain. ERP might be a candidate biomarker in child-adolescent psychiatry, considering its ability to reflect cognitive and behavioral functions in humans. For the EEG study of psychiatric diseases in children and adolescents, several ERP components have been used, such as mismatch negativity, P300, error-related negativity (ERN), and reward positivity (RewP). Regarding executive functions and inhibition in patients with attention-deficit/hyperactivity disorder (ADHD), P300 latency, and ERN were significantly different in patients with ADHD compared to those in the healthy population. ERN showed meaningful changes in patients with anxiety disorders, such as generalized anxiety disorder, separation anxiety disorder, and obsessive-compulsive disorder. Patients with depression showed significantly attenuated RewP compared to the healthy population, which was related to the symptoms of anhedonia.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.18 no.1
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• pp.58-65
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• 2007

Objectives : Motivational factor is a unique contributor to the typically poor academic performance of children with ADHD. However, few study has directly intervened learning motivation in children with ADHD. We conducted this study to explore the direct effects of the learning motivation improvement program applied to children with ADHD. Method The program was designed in order to increase an interest-inducing educational intervention, an academic skills integration, a basic learning activity (reading, writing, and math), and children's self-esteem. We conducted the program twice a week (total 10 sessions) and assessed learning motivation, teaming attitude, self-esteem, academic performance, and problem behaviors of participating children. Results : After the program, teachers reported improvement in teaming motivation. In addition, parents notified sisnificant reduction of problem behaviors. Children reported improvement in a few domains of teaming motivation and learning attitude. Conclusion : While loaming motivation is regarded as an important factor in education, there have been few studies considering this issue in both educational and psychiatric fields. The teaming motivation improvement would be needed in both field in order to reduce the deficits in academic performance in children with ADHD.

• Korean Parent-Child Health Journal
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• v.15 no.1
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• pp.1-13
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• 2012

Purpose: The purpose of this thesis is to investigate the experience of children with a schizophrenic parent. Methods: The research methods included biographical in-depth interviews, structured questionnaires, and child's drawings. Data were collected from September until November, 2005 at one university hospital, and interviews were recorded on audio tapes and thereby transcribed. The subjects were three adolescent children (10~15 years old) of a parent with schizophrenia. Results: This study has five themes: It is often the case that the children with a schizophrenic parent are uninformed about their parent's illness, have difficulties dealing with symptoms are confused about their parent's image and display contradictory feelings of fear and sympathy toward their father; The children tend to harbor expectations on mother's role in the family affairs, and simultaneously show pity for her; Family relations without solidarity caused by the absence of their father make the children feel severance, separation, and isolation in and out of the family; The children feel the burden to assume additional household responsibilities; The children are reluctant to mention their father's disease. Conclusion: the study subjects have met negativeness in both developmental characteristics and needs, which supports the need for intervention programs that meet their actual experience.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.19 no.3
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• pp.168-174
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• 2008

Objectives: The purpose of this study was to develop the Korean Somatization Scale for Children (KSS-C) and to evaluate the reliability and validity of this scale. Methods: Sixty-five children and adolescents with somatic symptoms were evaluated the KSS-C, Child Version, the Children's Depression Inventory (CDI), and the State-Trait Anxiety Inventory for Children (STAIC). 65 parents of the subjects evaluated the KSS-C, Parent Version and Korean version of the Child Behavior Checklist (K-CBCL). Psychometric properties and associations with the internalizing symptoms were. Results: Three factors were extracted by factor analysis. KSS-C was significantly correlated with the CDI, the STAIC, and the internalization, externalization and somatization scale of the K-CBCL. The KSS-C, Parent Version was significantly correlated with the KSS-C, Child Version. Frequently reported somatic symptoms in children were fatigue, headache, low energy, stomachache, and nausea. Conclusion: Both KSS-C, Child Version and KSS-P, Parent Version were valid and reliable instrument assess somatic symptoms in Korean children and adolescents.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.21 no.3
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• pp.214-217
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• 2018

Inflammatory bowel disease (IBD) is a well-recognized risk factor for thrombotic events in adults but data on children are scarce. In the great majority of adult patients, thrombotic events are usually deep vein thrombosis and pulmonary embolism. Other sites such as jugular veins are extremely rare. We present a case of Lemierre syndrome in an adolescent girl with active ulcerative colitis and discuss possible risk factors. This is the first reported case of severe Lemierre syndrome with thrombus extension to cranial veins in a patient with ulcerative colitis. Early recognition of Lemierre syndrome in patients who present with rapidly worsening symptoms of neck pain, fever and signs of pharyngitis is imperative because it increases a chance of favorable prognosis. It is important for pediatricians treating IBD patients not to underestimate possible thrombotic events in children with IBD. Recognition of additional risk factors is crucial for prompt diagnosis and adequate treatment.

• Korean Journal of Social Welfare
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• v.40
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• pp.5-37
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• 2000

The purpose of this study is to find out some characteristics of the family functions of single mothers to provide some useful data for the development of programs which may help single mothers to improve their family functions. The McMaster Family Assessment Device (FAD) which is composed of problem solving function (PS), communication function (CF), role function (RC), emotional reaction function (ER), emotional involvement (EI), behavioral control function (BC), and general function (GC) and McCubbins' FSI were administered to single mothers and their adolescent children and mothers and their adolescent children of ordinary families (control family). The single mothers' perception of their family function was lower than that of control family mothers in an the 7 categories of FAD. The perceptions of the family function of the single mothers' children were lower than those of control family mothers' children. There was on significant difference between the perceptions of single mothers and their children in PS, ER, EI, GC of their family. However, single mothers' perception in RC and BC was lower than that of their children, and the children's perception in CF were lower than that of their mothers. Single mothers who fall on the period of single motherhood was shorter than 7 years perceived their families' function as lower than that of single mothers' who fall on the periods of single motherhood longer than 7 years in all categories. Generally speaking, the single mothers' family functions were lower than that of control family. The different characteristics of each single mother's family functions should be considered in developing programs for single mothers.

• Korean Journal of Biological Psychiatry
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• v.16 no.1
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• pp.25-36
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• 2009

Objectives : The aim of this study was to investigate the association between Korean ADHD patients and the l/s polymorphism of serotonin transporter(5-HTTLPR). Methods : The study sample consisted of 189 Korean ADHD children diagnosed by Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version-Korean Version(K-SADS-PL), both parents of ADHD children, and 150 normal children. DNA were extracted from the blood of all samples, and genotyping was done. Based on the allele and genotype information, not only the case-control analysis between ADHD and normal children but also the family-based association test among ADHD children and their parents. Transmission disequilibrium test(TDT) were performed for family-based associated test(number of trio=113). The results of the clinical rating and neuropsychological tests were compared according to the l/s genotype of ADHD children. Results : In case-control analysis, there were no statistically significant difference of l/s gene polymorphism between ADHD and normal children in various kinds of analysis condition. In family-based association study, TDT failed to detect linkage disequilibrium between l/s gene polymorphism and ADHD in whole ADHD families. However, in the families of ADHD inattentive type only(number of trio=23), I allele was transmitted more preferentially in the proband with ADHD even if the number of families was small(${\chi}^2$=4.57, p=.032). In the analysis of the results from the clinical scales and neuropsychological tests in ADHD children, the score of the Novelty- Seeking of ADHD children with l/l genotype was significantly lower than with the other genotypes(F=3.15, p=.047), and that of Self Transcendence was significantly higher(F=4.25, p=.017). Conclusion : The results of this study suggest there were no significant genetic association between the 5- HTTLPR gene polymorphism and Korean ADHD.

• Journal of the Korea Convergence Society
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• v.8 no.7
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• pp.341-348
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• 2017

The aim of this study is to distinguish children with high-functioning autism spectrum disorder (ASD) from the norm group by identifying their Intelligence with Korean Wechsler Intelligence Scale for Children-Fourth Edition (K-WISC-IV) profile analysis. The article were administered to 90 children with high-functioning ASD (6-16) years and has surveyed the average of the Full scale IQ, index scores, and subtest scores of K-WISC-IV. Also, this study has conducted a single-subject T-test in order to verify whether Full scale IQ, index scores, subtest scores are different from those of the norm group. The results show that children with high-functioning ASD achieved significantly lower scores on Processing Speed Index, compared to the norm group. Furthermore, their scores in Comprehension, Picture Concept, Picture completion, Coding, and Symbol Search were significantly lower than those of the norm group. It is likely that what have turned out to be the cognitive weaknesses of high-functioning ASD children by K-WISC-IV analysis, including slow process speed, low social judgement, and difficulty in visual stimuli in everyday life are interrelated to their unique characters.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.31 no.4
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• pp.207-213
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• 2020

Objectives: Although aggressive behavior in children and adolescents with attention-deficit/hyperactivity disorder (ADHD) has previously shown correlations with hyperactivity/impulsivity, few studies have examined its association with inattention or the effect of working memory on aggressive behavior. This study aimed to assess the relationship between inattention and aggressive behavior and the effect of working memory on the relationship between inattention and aggressive behavior in children and adolescents with ADHD. Methods: Thirty-one children and 26 adolescents with ADHD were retrospectively investigated. The subjects completed the Korean Wechsler Intelligence Scale for Children-Fourth Edition (K-WISC-IV), the Korean Child Behavior Checklist (K-CBCL), and the Korean Children's Depression Inventory (CDI). Results: Inattention was positively correlated with aggressive behavior in children and adolescents with ADHD and working memory showed an insignificant correlation. However, working memory had a significant moderating effect on aggressive behavior by interacting with inattention. The moderating effect of working memory manifested when the working memory index score on the K-WISC-IV was 73.5 points or higher, and it had a significant effect on aggressive behavior. Conclusion: This study shows that the severity of inattention and hyperactivity/impulsivity should be addressed to provide appropriate treatment to children and adolescents with ADHD who exhibit aggressive behavior.