• Journal of Communications and Networks
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• 제15권4호
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• pp.338-351
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• 2013

Multiple-input multiple-output (MIMO) communication may provide high spectral efficiency through the deployment of a very large number of antenna elements at the base stations. The gains from massive MIMO communication come from the use of multi-user MIMO on the uplink and downlink, but with a large excess of antennas at the base station compared to the number of served users. Initial work on massive MIMO did not fully address several practical issues associated with its deployment. This paper considers the impact of channel aging on the performance of massive MIMO systems. The effects of channel variation are characterized as a function of different system parameters assuming a simple model for the channel time variations at the transmitter. Channel prediction is proposed to overcome channel aging effects. The analytical results on aging show how capacity is lost due to time variation in the channel. Numerical results in a multicell network show that massive MIMO works even with some channel variation and that channel prediction could partially overcome channel aging effects.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제12권3호
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• pp.1098-1112
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• 2018

Achievable sum rate and energy efficiency (EE) are investigated for the massive multiple-input multiple-output (Massive MIMO) downlink with channel aging in the time varying Ricean fading channel. Specifically, the expression of the achievable sum rate of the system for the maximum ratio transmission (MRT) precoder with aged channel state information (CSI) in the time varying Ricean fading channel is first presented. Based on the expression, the effect of both channel aging and the Ricean factor on the power scaling law are studied. It is found that the transmit power of base station (BS) is scaled down by $1/{\sqrt{M}}$(where M is the number of the BS antennas) when the Ricean factor K is equal to zero (i.e., time varying Rayleigh fading channel), indicating that aged CSI does not affect the power scaling law. However, the transmit power of the BS is scaled down by 1/M for the time varying Ricean fading channel (where $K{\neq}0$) indicating that the Ricean factor affects the power scaling law and sum rate, and channel aging only leads to a reduction of the sum rate. Second, the EE of the system is analyzed based on the general power consumption model. Both the theoretical analysis and the simulations show that the channel aging could degrade the sum rate and the EE of the system, and it does not affect the power scaling law.

• The Korean Journal of Physiology and Pharmacology
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• 제27권1호
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• pp.85-94
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• 2023

Ion channels regulate a large number of cellular functions and their functional role in many diseases makes them potential therapeutic targets. Given their diverse distribution across multiple organs, the roles of ion channels, particularly in age-associated transcriptomic changes in specific organs, are yet to be fully revealed. Using RNA-seq data, we investigated the rat transcriptomic profiles of ion channel genes across 11 organs/tissues and 4 developmental stages in both sexes of Fischer 344 rats and identify tissue-specific and age-dependent changes in ion channel gene expression. Organ-enriched ion channel genes were identified. In particular, the brain showed higher tissue-specificity of ion channel genes, including Gabrd, Gabra6, Gabrg2, Grin2a, and Grin2b. Notably, age-dependent changes in ion channel gene expression were prominently observed in the thymus, including in Aqp1, Clcn4, Hvcn1, Itpr1, Kcng2, Kcnj11, Kcnn3, and Trpm2. Our comprehensive study of ion channel gene expression will serve as a primary resource for biological studies of aging-related diseases caused by abnormal ion channel functions.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2003년도 하계종합학술대회 논문집 V
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• pp.2745-2748
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• 2003

In this paper, we implement the photoplethysmo-graphy system that have three channel pulse wave detects and one channel ECG amplifier. In order to detect the artery state, we measured the pulse waves at different positions, simultaneously. In general, arterial vascular system suffers the decrease of compliance, increase of resistance, and decrease of distensibility through aging. Therefore, we compared and analyzed variation of tile Pulse waves parameter both in time and frequency domains that is concerned with the changes of arterial characteries. And then evaluated the correlation coefficients between the parameters variation and the age group. As the result of experiment, we found that the Parameters have a significant correlation about aging.

• 한국에너지공학회:학술대회논문집
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• 한국에너지공학회 2003년도 춘계 학술발표회 논문집
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• pp.415-423
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• 2003

Korea Electric Power Research Institute(KEPRI) had worked a comprehensive Plant Lifetime Management (PLiM) project for a CANDU plant in corporation with Korea Hydro and Nuclear Power(KHNP). The project had been performed to understand the aging status of major components screened from the plant and to address provisions for the continued operation over its design life. A feasibility of the continued operation was reviewed in the aspects of technology, economics, and regulatory environments. This paper introduces general approach of aging assessment, screening of critical components and an experience of aging assessment for an example of fuel channel that is the most critical component in CANDU plant.

• Natural Product Sciences
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• 제27권3호
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• pp.193-200
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• 2021

Sophora flavescens Ait. (Fabaceae) is a medicinal plant widely founded in Northeast Asia, and its dried root (Kushen) has been used as a traditional Chinese herbal medicine. The therapeutic effects of Kushen in micturition disorder was not investigated comprehensively yet. In the present study, we examined and compared the efficacy of three batches of Kushen extract using different ethanol content through an in vitro cell-based assay. Among them, we chose the batch with the highest efficacy and augmented the volume of extract for industrial purpose. The bulk extract was examined in its efficacy in the in vitro cell-based assay, and the therapeutic effects through an in vivo behavioral assay of OAB rats. The main components of the extracts were analyzed by liquid chromatography. Cytotoxicity of the extracts was investigated by MTT assay. The overall efficacy of the extract was as much as, or more than, kurarinone, a potent BK_Ca channel activator. Thus, the extract was a potent relaxant of urinary smooth muscle by upregulating the activity of BK_Ca channel. The Kushen extract could be explored as an alternative medicine against overactive bladder patients indicating severe dysfunction of BK_Ca channel.

• The Korean Journal of Physiology and Pharmacology
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• 제1권2호
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• pp.117-125
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• 1997

The N-methyl-D-aspartate (NMDA) receptor-mediated glutamatergic neurotransmission is involved in synaptic plasticity, developmental processes, learning and memory and many neuropathological disorders including age-related diseases. In the present study, regulation of the NMDA receptor properties by various ligands was investigated using $[^3H]MK-801$ binding studies in the synaptic membranes of young and aged rat forebrains. The binding in the presence of glutamate and glycine increased dramatically with growth between 1 and 6 weeks old, and thereafter declined gradually with aging. Glutamate, glycine or spermine respectively increased the binding with growth. Glutamate maintained the binding during aging, while glycine or spermine significantly decreased the binding in the aged brain. The maximum stimulation by glycine varied depending on the ages of brains. Greater sensitivity to glycine was observed at 1 week and 3 months and the sensitivity was significantly reduced in the aged brain. In contrast, spermine showed similar stimulation patterns in young and aged rats. These results indicated that the functional properties of the NMDA receptor-ion channel complex in young and aged rat forebrains are differentially regulated by agonists, and the reduction of the receptor function with normal aging may be, in some degree, due to the reduction of the receptor sensitivity to glycine.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2018년도 춘계학술대회
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• pp.453-454
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• 2018

AMOLED 패널은 LCD 패널의 대체제로 사용되고 있으며, 품질 개선을 위한 다양한 공정기술들이 연구되고 있다. 이러한 연구들은 에이징 보정을 진행해야 하고 에이징 보정 값을 추출하는 알고리즘이 필요한 실정이다. 이를 위해 본 논문에서는 AMOLED의 에이징 보정을 진행하기 위해 전압 설정 알고리즘을 제안한다. 전압 설정 알고리즘은 전압 설정의 보정 값을 산출하여 출력 전압을 조절 및 증폭하여 임베디드 보드 내 각 채널에 따라 요구되는 전압을 공급해줄 수 있을 것으로 사료된다.

• 한국분말야금학회:학술대회논문집
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• 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part2
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• pp.962-963
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• 2006

The precipitation behaviors of ${\gamma}"(Ni_3Nb)$ in four Ni-base alloys were investigated. The four alloys were forged Ni20Cr20Fe5Nb alloy, mechanically alloyed Ni20Cr20Fe5Nb alloy, IN 718 alloy and ECAPed(equal channel angular pressing) IN 718 alloy. Aging treatment was employed at either $600^{\circ}C$ or $720^{\circ}C$ for 20 hrs. The TEM observation and hardness test were performed to identify the formation of ${\gamma}"$. The precipitation of ${\gamma}"$ was noticed after aging at $600^{\circ}C$ for 20 hrs in the mechanically alloyed Ni20Cr20Fe5Nb alloy and ECAPed IN 718 alloy, while it was observed after aging at $720^{\circ}C$ for 20 hrs in the forged Ni20Cr20Fe5Nb alloy and IN 718 alloy before ECAP. The lower aging temperature for ${\gamma}"$ precipitation in the mechanically alloyed Ni20Cr20Fe5Nb alloy and ECAPed IN 718 alloy than in the forged Ni20Cr20Fe5Nb alloy and IN 718 alloy before ECAP appeared to be due to the severe plastic deformation which occurred during mechanical alloying or ECAP.

• 한국농공학회논문집
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• 제62권2호
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• pp.53-62
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• 2020

The purpose of this study is to estimate the channel water loss of agricultural water supply in the command areas belong to Yechon irrigation channel of Gyeongcheon reservoir located Mungyeong-si, which area experienced a severe drought in 2015. The channel water loss was estimated by comparison of the irrigation water requirements (IWR) and agricultural water supply of the field data from 2012 to 2015. Further analysis was conducted to define the conveyance loss estimated based on the leakage holes and illegal pumping spots investigated through the field survey, and the distribution loss obtained by subtracting conveyance loss from the channel water loss. The annual rainfall decreased gradually, but the contribution of effective rainfall, available rain water to crop, increased to IWR during the study period. These phenomena resulted in the increase of agricultural water supply, and hence made greater the channel water loss simultaneously. The average channel water losses estimated as 36.8 % with 7.1 % of the conveyance loss and 29.7 % of distribution loss respectively. The distribution loss seems to be related to total number of rainy days, and irrigation schedules, while the conveyance loss was caused by irrigation channel aging conditions and illegal intake problems. In order to achieve sustainable agricultural water resources, the channel water loss needs to be reduced through the restoration of aged irrigation facilities and effective water managements in the fields.