• Title/Summary/Keyword: Chang-eui

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Effect of Scutellaria baicalensis Georgi Extract on Oxidant-Induced Inhibition of Organic Cation in Rabbit Renal Cortical Slices (황금약침액(黃芩藥鍼液)이 가토(家兎)의 신피질절편(腎皮質切片)에서 Oxidant로 유발된 유기양이온의 이동장애에 미치는 영향(影響))

  • Son, In-suk;Cho, Tae-sung;Kwon, Hae-yon;Jo, Mi-hyeong;Youn, Hyoun-min;Jang, Kyung-jeon;Song, Choon-ho;Abn, Chang-beohm
    • Journal of Acupuncture Research
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    • v.19 no.2
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    • pp.211-220
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    • 2002
  • Objective : This study was undertaken to determine whether Scutellaria baicalensis Georgi extract (SbG) exerts the protective effect against oxidant-induced alterations in organic cation transport in the renal proximal tubule. Methods : Organic cation transport was estimated by examining alterations in tetraethylammonium (TEA) uptake in rabbit renal cortical slices. The slices were treated with 0.2 mM tBHP for 60 min at $37^{\circ}C$. tBl-IP caused an inhibition in TEA uptake by renal cortical slices. Such an effect was accompanied by depressed Na+-K+-ATPase activity and ATP depletion. Result : SbG prevented tBHP-induced inhibition of TEA uptake in a dose-dependent manner at the concentration ranges of 0.05-0.1%. SbG also prevented H2O2-induced reduction in TEA uptake. tBHP-induced inhibition of Na+-K+-ATPase activity and ATP depletion were significantly prevented by 0.05% SbG. Oxidants increased LDH release, which was blocked by SbG. Oxidants caused a significant increase in lipid peroxidation and its effect was prevented by SbG. Conclusion : These results suggest that SbG prevents oxidant-induced alterations in organic cation transport in rabbit renal cortical slices. Such protective effects of SbG may be attributed to inhibition of peroxidation of membrane lipid.

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The Clinical Study on Chronic Conjunctivitis or Xerophthalmia treated with The Hwangryunhaedock-tang Herbal Acupuncture Therapy (황련해독탕(黃連解毒湯) 약침요법을 통한 만성(慢性) 결막염(結膜炎) 또는 안구건조증(眼球乾燥證) 환자 1례에 대한 보고)

  • Lee Chae-Woo;Park In-Beohm;Kim Sang-Woo;Ahn Chang-Beohm;Song Choon-Ho;Jang Kyung-Jeon;Kim Cheol-Hong;Youn Hyoun-Min
    • Korean Journal of Acupuncture
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    • v.20 no.4
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    • pp.77-84
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    • 2003
  • Objective : This study was designed to investigate the effect of the Hwangryunhaedock-tang Herbal Acupuncture Therapy on Chronic Conjunctivitis or Xerophthalmia Methods : We injected distillation of the Hwangryunhaedock-tang(0.2cc) on both B-15(Shinsu-心兪), B-18(Kansu-肝兪) of patient and dropped it(0.6cc) in both eyes. We examined therapeutic value of Chronic Conjunctivitis or Xerophthalmia Results & Conclusions : The Hwangryunhaedock-tang Herbal Acupuncture Therapy was effective on reducing the symptoms. But further studies are required to concretely prove the effectiveness of the Hwangryunhaedock-tang Herbal Acupuncture Therapy for treating Chronic Conjunctivitis or Xerophthalmia.

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WBCEx1 Reduces Feeding Efficiency Ratio and Visceral Obesity in Obese Mice Induced by High Fat Diet (고지방식이 비만마우스에서 월비가출탕(越婢加朮湯)이 식이효율과 내장지방에 미치는 영향)

  • An, Jeong-Ran;Kang, Yeon-Kyeong;Chang, Dong-Ho;Lee, In-Seon;Shin, Soon-Shik;Jeong, Hae-Gyeong;Lee, Hee-Young;Lee, Hye-Rim
    • Journal of Korean Medicine Rehabilitation
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    • v.21 no.1
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    • pp.1-22
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    • 2011
  • Objectives : This study was undertaken to verify the effects of Wolbigachul-tang1(WBCEx1) on obesity using high fat diet-induced male mice and to investigate the molecular mechanisms involved. Methods : 8-week old C57BL/6 mice were divided into 5 groups; lean control, obese control, WBCEx1, 2, 3. After mice were treated with WBCEx1(water extract), 2(30% ethanol extract), 3(water extract; Ephedra sinica Stapf., Gypsum fibrosum) for 12 weeks, body weight gain, feeding efficiency ratio, plasma lipid and glucose metabolism, the messenger RNA(mRNA) expression of peroxisome proliferator activated receptor(PPAR)$\alpha$ target genes were measured. In addition, $PPAR{\alpha}$ target gene expression was examined in liver, white adipose tissue and skeletal muscle. Results : 1. WBCEx1-treated mice had significantly lower body weight gain and feeding efficiency ratio. 2. Consistent with the effects on body weight gain, WBCEx1 decreased the weights of epididymal and retroperitoneal white adipose tissue, inguinal subcutaneous adipose tissue, and brown adipose tissue. 3. WBCEx1 significantly decreased plasma triglyceride and total cholesterol levels. 4. The size of adipocytes were significantly decreased by WBCEx1, whereas the adipocyte number per unit area was increased. Hepatic lipid accumulation was decreased by WBCEx1. 5. WBCEx1 did not affect the mRNA expression of $PPAR{\alpha}$ target genes in liver, adipose tissue, and skeletal muscle. 6. Plasma asparate aminotransferase(AST), alanine aminotransferase(ALT), blood urea nitrogen(BUN) and creatine concentrations were in the physiological range. Liver and kidney weights were significantly lower following WBCEx treatment compared with obese controls, indicating that WBCEx does not show any toxic effects on liver and kidney. Conclusions : These results suggest that WBCEx1-induced body weight reduction is associated with appetite control and mediated by a mechanism other than the activation of $PPAR{\alpha}$.

Comparative study on the Satisfaction difference of Korean and Western Medical Services (한양방 의료서비스 만족도 비교연구)

  • Lee, Jeong Won;Kim, Chang Tae;Lee, Hai Woong
    • Journal of Society of Preventive Korean Medicine
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    • v.19 no.3
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    • pp.67-75
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    • 2015
  • Objective : In South Korea, there are two kinds of medical systems that have Western medical institution and Korean medical institution. Patients who use medical services have different satisfaction in this environment. This study explores the satisfaction difference of korean/western medical services. Method : The data for this study were collected through a self-administered survey to 680 subject from patients who use medical services. frequency analysis, factor analysis, t-test, ANOVA were used for the statistical analysis. Results : The result of factor analysis, three factors were extracted. That was Information, Environment, Human services. Overall, the satisfaction scores of Korean medical service was higher than western medical service. Especially the human service satisfaction of the korean clinic was higher than western clinic. Conclusion : The satisfaction score of korean/western medical services is different. It is necessary to develop the medical management strategy and medical policy including korean medical system.

기능성 두통에 대한 황련해독탕약침(黃連解毒湯藥鍼)의 임상적 연구

  • Kim, Hong-Ki;Youn, Hyoun-Min;Ahn, Chang-Beohm
    • Journal of Pharmacopuncture
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    • v.9 no.3 s.21
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    • pp.131-138
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    • 2006
  • Objective : The aim of this study was to investigate the effect of HHT(Hwangryunhaedoktang Herbal-Acupuncture) on functional headache. Methods : 26 clinical experiment participants who experienced functional headache were gathered. The qualified patients were classified in two group, Normal saline injection group and Hwangryunhaedoktang Herbal-Acupuncture group. NS group was injected normal saline and HHT group was injected HHT at GB20, GB21, LI4. Treatment was applied 4 times every second day. The effects of both groups were analyzed using VAS scores and BPI(Brief Pain Inventory). Result : The VAS pain scores improved in both groups. the BPI scores decreased only in HHT group. The decrease rate of VAS scores and BPI scores was larger in HHT group. Conclusion : These results provided that HHT group is more effective than NS group. For clearly comparing the Effect of Hwangryunhaedoktang Herbal-Acupuncture on functional headache, it is need more sample's number and more treatment's duration.

Progressive Process planning and die design to improve the formability in fine blanking of the lock plate in car seatbelt (자동차 좌석벨트의 록 플레이트의 정밀타발 시 성형성 향상을 위한 프로그레시브 공정 및 금형 설계)

  • Lee, Sang-Pill;Min, Byung-Hyun;Lee, Kwan-Young;Ko, Young-Jun;Kim, Chul;Kim, Chang-Ho
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.12 no.6
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    • pp.84-92
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    • 2013
  • This study improves the formability in fine-blanking the lock plate of car seat belts using a low carbon steel(SM35C) plate. The optimal die design for the forming process is proposed using rules for process planning based on theories and field experiences. The optimal design is analyzed using commercial finite element software in order to solve the fracture problems in the extrusion process. Through the improved layout based on the FEM results, the fracture of the extruded part and the roll over problem are solved. Furthermore, it is demonstrated through the shown from experiments that the extruded part does not break in the modified die.

Development of Photovoltaic Output Power Prediction System using OR-AND Structured Fuzzy Neural Networks (OR-AND 구조의 퍼지 뉴럴 네트워크를 이용한 태양광 발전 출력 예측 시스템 개발)

  • Kim, Haemaro;Han, Chang-Wook;Lee, Don-Kyu
    • Journal of IKEEE
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    • v.23 no.1
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    • pp.334-337
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    • 2019
  • In response to the increasing demand for energy, research and development of next-generation energy is actively carried out around the world to replace fossil fuels. Among them, the specific gravity of solar power generation systems using infinity and pollution-free solar energy is increasing. However, solar power generation is so different from solar energy that it is difficult to provide stable power and the power production itself depends on the solar energy by region. To solve these problems in this paper, we have collected meteorological data such as actual regional solar irradiance, precipitation, temperature and humidity, and proposed a solar power output prediction system using logic-based fuzzy Neural Network.

Research on Airport Public Art Design Elements and Preferences Based on Big Data Sentiment Analysis (빅데이터 감성분석에 따른 공항 공공예술 디자인 요소 및 선호도 연구)

  • Zhang, Yun;Zou, ChangYun;Kim, CheeYong
    • Journal of Korea Multimedia Society
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    • v.25 no.10
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    • pp.1499-1511
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    • 2022
  • In the context of globalization, circulation between cities has become more frequent. The airport is no longer just a place for boarding, disembarking, and transportation, but a public place that serves as the communication function of the "aviation city". The intervention of public art in the airport space not only gives users a sense of space experience, but also becomes a unique carrier for city and country image shaping. The purpose of this paper is to study the emotional value brought by airport public art to users, and to investigate the correlation analysis of public art design elements and user preferences based on this premise. The research methods are machine learning method and SPSS 21.0. The user's emotional value is introduced in the big data evaluation, and the preference and inclination of airport users to various elements of public art are analyzed by questionnaire. Through the research conclusion, the preference and main contradiction of users in the airport for the four dimensions of public art design elements are obtained. Opinions and optimization methods to provide reference data and theoretical support for public art design.

Calcaneal Osteomyelitis Presenting as a Paradoxical Reaction during Treatment of Multidrug-Resistant Tuberculosis (다제내성 결핵의 치료 중 역설적 반응으로 나타난 종골 골수염)

  • Han, Yong Hyun;Lee, Chang Hwa;Bae, Min Joon;Hwang, Kihun
    • Clinical Pain
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    • v.18 no.2
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    • pp.102-106
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    • 2019
  • Tuberculosis in the foot progresses gradually; thus, diagnosis is usually delayed, and early treatment is rarely provided. If osteomyelitis occurs due to delayed diagnosis and treatment, surgical treatment should be considered. We report the case of a 46-year-old man with osteomyelitis of the calcaneus who was diagnosed with multidrug-resistant pulmonary tuberculosis and he was treated with anti-tuberculosis drugs. Bilateral adrenal masses, abscess of both testes and a small wound in the left plantar heel were observed. Both adrenal masses and abscess were regarded as paradoxical reaction of anti-tuberculosis treatment. After 1 month, he developed a pain in the left plantar heel that was compatible with calcaneal osteomyelitis in radiological features. He underwent right orchiectomy for right scrotal abscess aggravation and surgical treatment for left calcaneal osteomyelitis. Mycobacterium tuberculosis was confirmed by polymerase chain reaction. The patient was immobilized by cast for 8 weeks and the heel pain gradually improved.

Design of the Inverter Motor Drive System Applied to PFC using Interleaving Method (인터리빙 PFC를 적용한 모터구동 인버터 시스템 설계)

  • Yoon, Seong-Sik;Choi, Hyun-Eui;Kim, Tae-Woo;Ahn, Ho-Kyun;Park, Seung-Kyu;Yoon, Tae-Sung;Kwak, Gun-Pyoung
    • Journal of the Korean Society for Precision Engineering
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    • v.27 no.4
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    • pp.14-19
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    • 2010
  • In this paper, using interleaved power factor correction how to improve the inverter efficiency studied. Interleaved method can reduce the conduction losses and the inductor energy. Generally, critical conduction mode (CRM) boost PFC converter used low power level because of the high peak currents. if you use the interleaved mode, CRM PFC can be used medium or high power application. interleaved CRM PFC can reduce current ripple for higher system reliability and size of buck capacitor and EMI filter size. Interleaved CRM PFC that is installed in front of inverter can maintain the constant voltage regardless of the input voltage.