• 한국자동차공학회논문집
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• 제9권6호
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• pp.186-194
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• 2001

To meet the challenge of testing increasingly complex automotive control systems, the real-time hardware-in-the-loop(HIL) simulation technology has been developed. In this paper, a strategy for evaluation of semiactive suspension systems using real-time HIL simulation is presented. A multibody vehicle model is adopted to simulate vehicle dynamic motions accurately. Accuracy of the vehicle simulation results is compared to that of the real vehicle field test and proven to be very accurate. The controller and stepping motor to adjust semi-active damper stage are equipped as external hardwares and connected to the real-time computer which has vehicle dynamic model. Open and closed loop test methods are used to evaluate a controlled suspension system and the system's operations are verified it is found that the proposed evaluation methods can be used well for the verification of semi-active suspension systems.

• 상하수도학회지
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• 제27권1호
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• pp.121-128
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• 2013

The concern for dissolved phosphate in water/wastewater has been increasing because of the risk for eutrophication. A variety of conventional and advanced technologies were applied to meet the enforced new regulation of phosphate around the world. However, there still remained a lot of challenge because most introduced/developed method, for example, biological and physic-chemical treatment is not easy to satisfy the new regulation of phosphate in water. In order to meet the new regulation, the application of ion exchanger has been tried which showed that the removal efficiency for phosphate was strongly determined by in the presence of the competing ion, especially sulfate. As results, a new class of ion exchanger governed by ligand exchange was developed and investigated to increase the selectivity for phosphate. The current study using organic/inorganic anion exchanger developed with Lewis acid-base interaction confirms the selectivity for phosphate over sulfate. According to isotherm test and column test, the value of the maximum phosphate uptake (Q) showed 64 mg/g as $po{_4}^{3-}$ and the breakthrough for phosphate occurs after 1000 min and completely finishes at 2500 min, respectively.

• 약학회지
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• 제45권1호
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• pp.39-45
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• 2001

The pork meat has been reported as one of the food occurring allergic reactions predominantly to korean. To identify the potential food allergens in pork meat, sera were collected from 25 allergic patients to the pork meat and 10 allergic patients not to pork meat as well as 5 normal subjects after skin prick test and open food challenge test. Crude extracts were prepared by blending raw pork meat in phosphate buffered saline (pH 7.0) and the heat treatment on crude extracts was carried to characterize sensibility of the allergens to heat. ELISA was performed to determine specific IgE antibody levels of allergic patients to pork meat, and resulted in twofold higher mean value than that of tolerated patients. Extracted proteins from pork meat was separated with SDS-PAGE followed by immunoblotting using sera from pork sensitive patients and control subjects, respectively. The IgE binding response to pork meat by immunobots correlated with quantitative specific IgE value of each person. Immunoblots showed four prominent IgE-binding bands (66, 60, 50, 44 kDa) in crude extract, but two bands of those (60, 44 kDa) were heat-labile. These results suggest that most prominent allergens from pork meat are four components(66, 60, 50, 44 kDa) in korean and the heat treatment on allergen is additional parameter to characterize allergen.

• 지역사회간호학회지
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• 제7권1호
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• pp.18-28
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• 1996

This study was carried out to explore the direction of job involvement of public health nurses and explore the way for improving services of public health center in Korea. The subjects were consisted of 164 nurses who were working at public health centers in Chonbuk. The data were collected by self-reporting questionnaire from Jan. 15 to Jan. 27, 1996. The instrument used in this study was Likert-type scale which Job Involvement Scale developed by Kanungo. The questionnaires of organizational and job characteristic were made through reviewing literatures. The data were analyzed by frequency, percentage, t-test, one-way ANOVA, Scheffe test, and Pearson's correlation coefficient with SPSSPC+ program. Major findings were as follows : 1. Mean scores for job involvement were 3.0879 on a 5 point scale. 2. In the personal variables, professional experience(t=-2.18, p=.031), position(t=2.34, p=.021), and age(F=-1.94, p=.038) were statistically significant in job involvement. 3. The variables to job characteristic were statistically significant in job involvement: job challenge (r=.4785, p=.000), role ambiguity (r=-.3141, p=.000), task significance (r=.2714, p=.000), and role conflict(r=-.2166, p=.003). 4. The variables to organizational characteristic were statistically significant in job involvement : formalization(r=.3184, p=.000) and human centered organizational characteristic (r=.2450, p=.001).

• Computers and Concrete
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• 제23권1호
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• pp.11-23
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• 2019

Nowadays, the characterization of Ultra-High Performance Fiber-Reinforced Concrete (UHPFRC) tensile behavior still remains a challenge for researchers. For this purpose, a simplified closed-form non-linear hinge model based on the Third Point Bending Test (ThirdPBT) was developed by the authors. This model has been used as the basis of a simplified inverse analysis methodology to derive the tensile material properties from load-deflection response obtained from ThirdPBT experimental tests. In this paper, a non-linear finite element model (FEM) is presented with the objective of validate the closed-form non-linear hinge model. The state determination of the closed-form model is straightforward, which facilitates further inverse analysis methodologies to derive the tensile properties of UHPFRC. The accuracy of the closed-form non-linear hinge model is validated by a robust non-linear FEM analysis and a set of 15 Third-Point Bending tests with variable depths and a constant slenderness ratio of 4.5. The numerical validation shows excellent results in terms of load-deflection response, bending curvatures and average longitudinal strains when resorting to the discrete crack approach.

• Journal of Genetic Medicine
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• 제18권1호
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• pp.31-37
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• 2021

Purpose: To summarize the results of chromosomal microarray analysis (CMA) for copy number variants (CNVs) detection and clinical utility in a single tertiary hospital. Materials and Methods: We performed CMA in 46 patients over the course of two years. Detected CNVs were classified into five categories according to the American College of Medical Genetics and Genomics guidelines and correlated with clinical manifestations. Results: A total of 31 CNVs were detected in 19 patients, with a median CNV number per patient of two CNVs. Among these, 16 CNVs were classified as pathogenic (n=3) or likely pathogenic (LP) (n=11) or variant of uncertain significance (n=4). The 16p11.2 deletion and 16p13.11 deletion classified as LP were most often detected in 6.5% (3/46), retrospectively. CMA diagnostic yield was 24.3% (9/37 patients) for symptomatic patients. The CNVs results of the commercial newborn screening test using next generation sequencing platforms showed high concordance with CMA results. Conclusion: CMA seems useful as a first-tier test for developmental delay with or without congenital anomalies. However, the classification and interpretation of CMA still remained a challenge. Further research is needed for evidence-based interpretation.

• The Journal of Asian Finance, Economics and Business
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• 제8권3호
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• pp.683-693
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• 2021

Shipping has become an important sector in supporting social, economic, government, defense, security, cultural and other sectors to unite separate islands and broad seas. Thus, ports automatically become an important facility in Indonesia. The purpose of this research is to test and explain the effect of Organizational readiness for change, Service Innovation, and Corporate Image on Perceived opportunity and challenge. The research model with inferential analysis uses Structural Equation Modeling (SEM) analysis with the WarpPLS approach, expected to answer the statements of problem and be able to test the desired hypothesis. The model development in this research was based on the background, statements of problem, conceptual framework and research hypotheses. The model referred to is "Complete and Comprehensive Port." Its development was carried out through studying and synthesizing various sources. The most important source is the results of literature review in the form of theoretical developments and research results, then continued with compilation. The use of Organizational Change Readiness, Service Innovation, and Corporate Image in improving Port Competitiveness is seen as one of the novelties of this research, specifically the use of the Organizational Change Readiness variable which is often used in high-flexibility companies but now used in port companies as well.

• International Journal of Computer Science & Network Security
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• 제24권2호
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• pp.150-154
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• 2024

In recent years, there are extensive researches on the applications of machine learning to the automation and decision support for medical experts during disease detection. However, the performance of machine learning still needs improvement so that machine learning model produces result that is more accurate and reliable for disease detection. Selecting the hyper-parameter that could produce the possible maximum classification accuracy on medical dataset is the most challenging task in developing decision support systems with machine learning algorithms for medical dataset classification. Moreover, selecting the features that best characterizes a disease is another challenge in developing machine-learning model with better classification accuracy. In this study, we have proposed an optimized decision tree model for heart disease classification by using heart disease dataset collected from kaggle data repository. The proposed model is evaluated and experimental test reveals that the performance of decision tree improves when an optimal number of features are used for training. Overall, the accuracy of the proposed decision tree model is 98.2% for heart disease classification.

• Fisheries and Aquatic Sciences
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• 제27권3호
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• pp.159-170
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• 2024

Research to obtain molecular markers related to the major histocompatibility complex (MHC) gene in both strains of gourami is essential to increase the success of the selection program of disease resistance traits. Using a completely randomized design (CRD), the challenge test consists of four treatments and seven replications. The treatment was Jambi gourami injected with PBS (KJ), Kalimantan gourami injected with PBS (KK), Jambi strain injected with Aeromonas hydrophila (GJ), and Kalimantan strain injected with A. hydrophila (GK). The GJ population was more resistant to A. hydrophila than the GK population. The MHC II gene was detected in both test strains (GJ and GK), both resistant and susceptible fish. However, there were differences in the results of amplifying the MHC II gene in susceptible and resistant fish. Two DNA fragments approximately 400 and 585 bp were detected in the genome of susceptible fish, while in the genome of susceptible fish, only one DNA fragment was detected (400 bp). Therefore, the MHC II gene fragment with a size of about 585 bp can be used as a potential candidate for specific molecular markers to obtain resistance to A. hydrophila bacteria in the giant gourami.

• Fisheries and Aquatic Sciences
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• 제26권10호
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• pp.583-592
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• 2023

Celebes rainbow (Marosantherina ladigesi) is one of Indonesia's exported ornamental fish commodities, but the exploitation of this fish only relies on wild catches. The rise of unlimited fishing, especially those using poison, has changed the aquatic environment, threatening sustainability and causing fish extinction. This study aimed to evaluate the effectiveness of several types of feed in improving the absolute growth rate (AGR), specific growth rate (SGR), survival rate (SR), feed conversion ratio (FCR), feed efficiency (FE), hematology, and immune response of Celebes rainbow. The fish used in this study were male ornamental Celebes rainbow (M. ladigesi) weighing 1.32 ± 0.21 g/ind, reared in 54 L-aquariums at a stocking density of 30 individuals/aquarium for six weeks. The fish were fed according to the test diet consisting of live Tubifex sp worms, dry Tubifex sp worms, Spirulina platensis, and crumble pellets. The parameters observed were AGR, SGR, SR, FCR, FE, hematology, intestinal histology, liver histology, and a challenge test with the pathogenic bacteria Aeromonas hydrophila. The results showed that fish-fed live Tubifex sp worms had better AGR, SGR, SR, FCR, FE, hematology, and disease resistance compared to all other treatments. These results indicate that live Tubifex sp worms are the best feed for rearing Celebes rainbow.