• Journal of the Korea Institute of Building Construction
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• v.18 no.2
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• pp.141-149
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• 2018

In this study, compacting, passing performance, segregation resistance and rheological properties were tested to improve the stability of fresh concrete in the production and construction of self-compacting concrete (SCC) using hollow glass powder(GB). As a result, T50 reaching time was shortened up to amount of GB $2.0kg/m^3$. The compacting according to the amount of GB was improved by ball bearing effect of GB. However, T50 reaching time was slightly increased at $4.0kg/m^3$. In the case of passing performance, the result showed that plain was Class 1, GB $0.5{\sim}2.0kg/m^3$ was Class 0, GB $4.0kg/m^3$ was Class 1. Therefore, the passing performance was improved with 'No blocking' up to amount of GB $2.0kg/m^3$. Passing performance Block step (PJ) number by J-ring method was also best at GB $1.0kg/m^3$. In the case of segregation resistance according to the amount of GB, dynamic segregation resistance was increased compared to plain regardless of the amount of GB. And static segregation resistance showed 2.5% of segregation rate at GB $1.0kg/m^3$. Therefore, it was greatly improved compared to plain (12.5%). In the case of rheology property according to the amount of GB, plastic consistency by increasing of GB content didn't show big difference. However, yield stress by increasing of GB content was decreased with GB $1.0kg/m^3$. In conclusion, GB $1.0kg/m^3$ was effective for improvement of compacting, passing performance and yield stress. Also, it will be useful for stability of SCC by improving segregation.

• BMB Reports
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• v.47 no.12
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• pp.660-665
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• 2014

Stathmin 1 is a microtubule destabilizer that plays an important role in cell cycle progression, segregation of chromosomes, clonogenicity, cell motility and survival. Stathmin 1 overexpression has been reported in malignant hematopoietic cells and Stathmin 1 inhibition reduces the highly proliferative potential of leukemia cell lines. However, during the differentiation of primary hematopoietic cells, Stathmin 1 expression decreases in parallel to decreases in the proliferative potential of early hematopoietic progenitors. The scope of the present review is to survey the current knowledge and highlight future perspectives for Stathmin 1 in normal and malignant hematopoiesis, with regard to the expression, function and clinical implications of this protein.

• Molecules and Cells
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• v.27 no.2
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• pp.135-142
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• 2009

The centrosome, an organelle comprising centrioles and associated pericentriolar material, is the major microtubule organizing center in animal cells. For the cell to form a bipolar mitotic spindle and ensure proper chromosome segregation at the end of each cell cycle, it is paramount that the cell contains two and only two centrosomes. Because the number of centrosomes in the cell is determined by the number of centrioles, cells have evolved elaborate mechanisms to control centriole biogenesis and to tightly coordinate this process with DNA replication. Here we review key proteins involved in centriole assembly, compare two major modes of centriole biogenesis, and discuss the mechanisms that ensure stringency of centriole number.

• Journal of the Korean Recycled Construction Resources Institute
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• v.6 no.3
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• pp.182-189
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• 2018

Controlled low strength material(CLSM), known as flowable fill is used sewer. This paper evaluates flowability, segregation, early strength and excavatability of CLSM made using standard soils such as SM, ML, CL, CH. Also, various mix proportions of CLSM containing kaolinite, red soil, Joomun Jin standard soil were developed and the mixing ratio optimized. It was considered as the flowability and early strength were severly affected by W/B, S/B, and early strength and flowability depend on standard soils which means the satisfaction conditions of CLSM were variety of standard soil conditions. Finally, not only optimal mixing proportions were deducted according to standard soil condition but confirmed effectiveness of bleeding and excavatability.

• Korean Journal of Metals and Materials
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• v.47 no.7
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• pp.440-446
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• 2009

Co base superalloys have been widely used for the parts of gas turbine due to their excellent strength, thermal fatigue, oxidation resistance and weldability at high temperature. In this study, directional solidifications were carried out at various solidification rates, including $0.5{\sim}300{\mu}m/s$ in the Co base superalloy FSX-414. The cellular interface were formed at a low solidification rate, $1{\mu}m/s$, and the dendritic interface was found at higher solidification rates, $5{\sim}300{\mu}m/s$. As the spacing of dendrite structure decreased, the size and spacing of eutectics decreased. Dendrite arm spacing decreased with increasing solidification rates and temperature gradient. It was interesting to find the $M_{23}C_{6}$ eutectic microstructure formed between $\gamma$ dendrites. Composition analysis showed that Cr and W were segregated severely between the dendrites, which resulted in the formation of Cr-rich $M_{23}C_{6}$ and W-rich MC carbides.

• Proceedings of the Korean Aquaculture Society Conference
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• 2003.10a
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• pp.20-20
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• 2003

We described the isolation, characterization and inheritance of twenty-seven microsatellite loci from olive flounder, Paralichthys olivaceus. All loci were found to be polymorphic, and had between five and 22 alleles with observed heterozygosity ranging from 0.161 to 1.0 in 31 individuals examined. Allele segregation patterns of all loci in controlled crosses of flounder were studied to assess the inheritability. Allele of all but 3 loci were segregated according to Mendelian transmission. However, 3 loci had a possibility of scoring errors of heterozygous individuals caused by unreproducible PCR amplification of a particular allele. 24 microsatellite loci are likely to be useful for studies of genome mapping, mating systems and population genetics in this species.

• Proceedings of the Korean Magnestics Society Conference
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• 2012.11a
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• pp.172-172
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• 2012

A Pt-skin $Pt_3Ni$(111) surface was reported to show high catalytic activity. In this study, we investigated the magnetic properties and electronic structures of the various oriented surfaces of bulk-terminated and Pt-segregated $Pt_3Ni$ by using a first-principles calculation method. The magnetic moments of Pt and Ni are appreciably enhanced at the bulk-terminated surfaces compared to the corresponding bulk values, whereas the magnetic moment of Pt on the Pt-segregated $Pt_3Ni$(111) surface is just slightly enhanced because of the reduced number of Ni neighboring atoms. Spin-decomposed density of states shows that the dz2 orbital plays a dominant role in determining the magnetic moments of Pt atoms in the different orientations. The lowering of the d-band center energy (-2.22 eV to -2.46 eV to -2.51 eV to -2.65 eV) in the sequence of bulk-terminated (100), (110), (111), and Pt-segregated (111) may explain the observed dependence of catalytic activity on surface orientation. Our d-band center calculation suggests that an observed enhanced catalytic activity of a $Pt_3Ni$(111) surface originates from the Pt-segregation.

• Proceedings of the Korea Association of Crystal Growth Conference
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• 1997.06a
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• pp.149-155
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• 1997

We have successfully grown colorless and transparent Rb-doped potassium niobate (KRN) single crystals using the top seeded solution growth(TSSG) technique. In our crystal growth experiments, the Rb doping concentrations within the melt range from 2-15 mol% relative to that of Nb$_2$O5. Atomic absorption measurements indicate that the Rb content in the KRN solid solution is rather low; the Rb segregation coefficient is found to be on the order of 0.05. It is believed that this is due to the relatively much larger Rb+ ionic radius compared to that of K+, rendering it more difficult for Rb to replace K in the KNbO$_3$(KN) host lattice. Preliminary single-pass second harmonic generation (SHG) experimental results indicate that there exists marginal improvement in the phase-matching temperature tolerance of KRN compared to that of pure Kn single crystals.

• BMB Reports
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• v.47 no.6
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• pp.299-310
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• 2014

Cohesin is a multi-protein complex composed of four core subunits (SMC1A, SMC3, RAD21, and either STAG1 or STAG2) that is responsible for the cohesion of sister chromatids following DNA replication until its cleavage during mitosis thereby enabling faithful segregation of sister chromatids into two daughter cells. Recent cancer genomics analyses have discovered a high frequency of somatic mutations in the genes encoding the core cohesin subunits as well as cohesin regulatory factors (e.g. NIPBL, PDS5B, ESPL1) in a select subset of human tumors including glioblastoma, Ewing sarcoma, urothelial carcinoma, acute myeloid leukemia, and acute megakaryoblastic leukemia. Herein we review these studies including discussion of the functional significance of cohesin inactivation in tumorigenesis and potential therapeutic mechanisms to selectively target cancers harboring cohesin mutations.

• Clinical and Experimental Reproductive Medicine
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• v.38 no.1
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• pp.1-5
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• 2011

The maturation process of mammalian oocytes accompanies an extensive rearrangement of the cytoskeleton and associated proteins. As this process requires a delicate interplay between the cytoskeleton and its regulators, it is often targeted by various external and internal adversaries that affect the congression and/or segregation of chromosomes. Asymmetric cell division in oocytes also requires specific regulators of the cytoskeleton, including formin-2 and small GTPases. Recent literature providing clues regarding how actin filaments and microtubules interact during spindle migration in mouse oocytes are highlighted in this review.