• Title/Summary/Keyword: Center Fusion

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A Comparison of the Clinical Outcomes of Decompression Alone and Fusion in Elderly Patients with Two-Level or More Lumbar Spinal Stenosis

  • Son, Seong;Kim, Woo Kyung;Lee, Sang Gu;Park, Chan Woo;Lee, Keun
    • Journal of Korean Neurosurgical Society
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    • v.53 no.1
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    • pp.19-25
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    • 2013
  • Objective : We compared the results of two surgical techniques by retrospective study of 60 elderly patients (65 years or older) who underwent either decompression alone or fusion for the treatment of two-level or more lumbar spinal stenosis. Methods : During the period of 2003 and 2008, two-level or more decompression alone or fusion was performed for lumbar spinal stenosis by three surgeons at our institution. Patients were allocated to two groups by surgical modality, namely, to a decompression group (31 patients) or a fusion group (29 patients). Overall mean age was 71.1 years (range, 65-84) and mean follow-up was 5.5 years (range, 3-9). A retrospective review of clinical, radiological, and surgical data was conducted. Results : No significant difference between the two groups was found with respect to age, follow-up period, surgical levels, or preoperative condition. At the last follow-up, correction of lumbar lordotic angle (determined radiologically) was better in the fusion group. However, clinical outcomes including visual analogue scale, Oswestry Disability Index, and the Odom's criteria were not significantly different in the two groups. On the other hand, surgical outcomes, such as, operation time, estimated blood loss, and surgical complications were significantly better in the decompression alone group. Conclusion : Our findings suggest that decompressive laminectomy alone achieves good outcomes in patients with two-level or more lumbar spinal stenosis, associated with an advanced age, poor general condition, or osteoporosis.

Preparation and Release Behavior of Ipriflavone-Loaded PLGA Microsphere for Tissue Engineered Bone (이프리플라본을 함유한 생분해성 PLGA 미립구의 제조 및 조직공학적 골재생을 위한 영향평가)

  • So, Jung-Won;Jang, Ji-Wook;Kim, Soon-Hee;Kim, Geun-Ah;Choi, Jin-Hee;Rhee, John-M.;Son, Young-Suk;Min, Byoung-Hyun;Khang, Gil-Son
    • Polymer(Korea)
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    • v.33 no.1
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    • pp.26-32
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    • 2009
  • The aim of this research was to prepare microparticulate systems based on poly (lactide-co-glycolide)(PLGA) for the local release of ipriflavone in order to reduce bone loss. We developed the IP loaded PLGA microspheres using relatively simple oil-in-water(O/W) solvent evaporation method. HPLC was used to perform the in vitro release test of IP and morphology of cell attached on the micro-spheres was investigated using SEM. Cytotoxicity was assayed by cell counting kit-8 (CCK-8) test. Osteogenic differential cells were analyzed by ALP activity. Through RT-PCR analysis, we observed osteocalcin, ALP, and Type I collagen mRNA expression. The release of IP in vitro was more prolonged over 42 days and IP/PLGA microspheres showed the improvement on the cell proliferation, ALP activity and RT-PCR comparing with control (only PLGA). This initial research will be used to direct future work involved in developing this composite injectable bone tissue engineering system.

A Correlation Between Crack Growth and Abrasion for Selected Rubber Compounds

  • Lee, Hyunsang;Wang, Wonseok;Shin, Beomsu;Kang, Seong Lak;Gupta, Kailash Chandra;Nah, Changwoon
    • Elastomers and Composites
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    • v.54 no.4
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    • pp.313-320
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    • 2019
  • A typical wear pattern was reported to resemble the fatigue crack growth behavior considering its mechanism, especially for amorphous rubbers such as styrene-butadiene rubber (SBR). In this study, the wear and crack growth rates were correlated using two separate experiments for carbon black and silica-reinforced selected rubber compounds. The wear rate was determined using a blade-type abrasion tester, where the frictional energy input during wearing was measured. The crack propagation rate was determined under different tearing energy inputs using a home-made fatigue tester, with a pure-shear test specimen containing pre-cracks. The rates of abrasion and crack propagation were plotted on a log-log scale as a function of frictional and tearing energies, respectively. Reasonable agreement was observed, indicating that the major mechanism of the abrasion pattern involved repeated crack propagation.

Comparison of various image fusion methods for impervious surface classification from VNREDSat-1

  • Luu, Hung V.;Pham, Manh V.;Man, Chuc D.;Bui, Hung Q.;Nguyen, Thanh T.N.
    • International Journal of Advanced Culture Technology
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    • v.4 no.2
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    • pp.1-6
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    • 2016
  • Impervious surfaces are important indicators for urban development monitoring. Accurate mapping of urban impervious surfaces with observational satellites, such as VNREDSat-1, remains challenging due to the spectral diversity not captured by an individual PAN image. In this article, five multi-resolution image fusion techniques were compared for the task of classifting urban impervious surfaces. The result shows that for VNREDSat-1 dataset, UNB and Wavelet tranformation methods are the best techniques in reserving spatial and spectral information of original MS image, respectively. However, the UNB technique gives the best results when it comes to impervious surface classification, especially in the case of shadow areas included in non-impervious surface group.

Structural Analysis of the Ectodomain of HIV Gp41 and Implication on the Gp41 Assisted Membrane Fusion

  • Ryu, Jae-Ryen;Lee, Jung;Suh, Mu-Jin;Yu, Yeong-Sook;Yu, Yeon-Gyu
    • Proceedings of the Korean Biophysical Society Conference
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    • 1996.07a
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    • pp.33-33
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    • 1996
  • An ectodomain of gp41, the transmembrane fusion protein of HIV, without the fusion peptide region was expressed using pET system in E. coli. The expressed protein gp41core, was isolated as inclusion body and was purified by ion-exchange chromatography after solubilized in 6M urea. The purified denatured protein was renaturated and the folded domain of gp41core was identified by the presence of the proteolysis resistence domain and a high content of ${\alpha}$-helical secondary structure. (omitted)

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Fusion of Gamma and Realistic Imaging (감마영상과 실사영상의 Fusion)

  • Kim, Yun-Cheol;Yu, Yeon-Uk;Seo, Young-Deok;Moon, Jong-Woon;Kim, Yeong-Seok;Won, Woo-Jae;Kim, Seok-Ki
    • The Korean Journal of Nuclear Medicine Technology
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    • v.14 no.1
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    • pp.78-82
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    • 2010
  • Purpose: Recently, South Korea has seen a rapidly increased incidence of both breast and thyroid cancers. As a result, the I-131 scan and lymphoscintigraphy have been performed more frequently. Although this type of diagnostic imaging is prominent in that visualizes pathological conditions, which is similar to previous nuclear diagnostic imaging techniques, there is not much anatomical information obtained. Accordingly, it has been used in different ways to help find anatomical locations by transmission scan, however the results were unsatisfactory. Therefore, this study aims to realize an imaging technique which shows more anatomical information through the fusion of gamma and realistic imaging. Materials and Methods: We analyzed the data from patients who were examined by the lymphoscintigraphy and I-131 additional scan by Symbia Gamma camera (SIEMENS) in the nuclear medicine department of the National Cancer Center from April to July of 2009. First, we scanned the same location in patients by using a miniature camera (R-2000) in hyVISION. Afterwards, we scanned by gamma camera. The data we obtained was evaluated based on the scanning that measures an agreement of gamma and realistic imaging by the Gamma Ray Tool fusion program. Results: The amount of radiation technicians and patients were exposed was generated during the production process of flood source and applied transmission scan. During this time, the radiation exposure dose of technicians was an average of 14.1743 ${\mu}Sv$, while the radiation exposure dose of patients averaged 0.9037 ${\mu}Sv$. We also confirmed this to matching gamma and realistic markers in fusion imaging. Conclusion: Therefore, we found that we could provide imaging with more anatomical information to clinical doctors by fusion of system of gamma and realistic imaging. This has allowed us to perform an easier method in which to reduce the work process. In addition, we found that the radiation exposure can be reduced from the flood source. Eventually, we hope that this will be applicable in other nuclear medicine studies. Therefore, in order to respect the privacy of patients, this procedure will be performed only after the patient has agreed to the procedure after being given a detailed explanation about the process itself and its advantages.

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OVERVIEW OF SUPERCONDUCTING MAGNET POWER SUPPLY SYSTEM FOR THE KSTAR 1ST PLASMA EXPERIMENT

  • Choi, Jae-Hoon;Yang, Hyung-Lyeol;Ahn, Hyun-Sik;Jang, Gye-Yong;Lee, Dong-Keun;Kim, Kuk-Hee;Hahn, Sang-Hee;Kim, Chang-Hwan;Hong, Jae-Sic;Chu, Yong;Kong, Jong-Dae;Hong, Seong-Lok;Hwang, In-Sung
    • Nuclear Engineering and Technology
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    • v.40 no.6
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    • pp.459-466
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    • 2008
  • The KSTAR Magnet Power Supply (MPS) was dedicated to the SC coil commissioning and $1^{st}$ plasma experiment as a part of the system commissioning. Although many efforts to develop large-current power supplies that are useful for high power electronic devices have been made in various application fields, such as for large metal-plating devices, there were clear discrepancies between conventional power supply technologies and that for the SC coils due to the special SC coil load conditions. Therefore, most of the power supply technologies for the SC coils were a challenge in the domestic research area due to their limited application. However, the MPS commissioning result showed that all of the hardware and controlling software operated well, and this result finally led to the success of SC coil commissioning and the KSTAR $1^{st}$ plasma experiment. This paper will describe key features of KSTAR MPS for the $1^{st}$ plasma experiment, and will also report the commissioning results of the magnet power supplies.

A Development of Wireless Sensor Networks for Collaborative Sensor Fusion Based Speaker Gender Classification (협동 센서 융합 기반 화자 성별 분류를 위한 무선 센서네트워크 개발)

  • Kwon, Ho-Min
    • Journal of the Institute of Convergence Signal Processing
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    • v.12 no.2
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    • pp.113-118
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    • 2011
  • In this paper, we develop a speaker gender classification technique using collaborative sensor fusion for use in a wireless sensor network. The distributed sensor nodes remove the unwanted input data using the BER(Band Energy Ration) based voice activity detection, process only the relevant data, and transmit the hard labeled decisions to the fusion center where a global decision fusion is carried out. This takes advantages of power consumption and network resource management. The Bayesian sensor fusion and the global weighting decision fusion methods are proposed to achieve the gender classification. As the number of the sensor nodes varies, the Bayesian sensor fusion yields the best classification accuracy using the optimal operating points of the ROC(Receiver Operating Characteristic) curves_ For the weights used in the global decision fusion, the BER and MCL(Mutual Confidence Level) are employed to effectively combined at the fusion center. The simulation results show that as the number of the sensor nodes increases, the classification accuracy was even more improved in the low SNR(Signal to Noise Ration) condition.

Effect of Ratio of Demineralized Bone Powder with Alginate Microcapsules on Articular Cartilage Regeneration (탈미네랄 골분이 비율별로 포접된 알지네이트 미세캡슐을 이용한 조직공학적 연골재생)

  • Kim, A Ram;Kim, Hye Min;Lee, Jung Keun;Lee, Ji Hye;Song, Jeong Eun;Yoon, Kun Ho;Lee, Dongwon;Khang, Gilson
    • Polymer(Korea)
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    • v.36 no.6
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    • pp.768-775
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    • 2012
  • Alginate, obtained from the seaweeds, is a widely used biomaterial for cell transplantation, since its positive effect on viability of capsulized cells and its easier encapsulation capability of living cells. Demineralized bone powder (DBP), derived from the natural bone tissue, is widely applied for clinical trials for its low rate of reaction and antigenicity. A chondrocyte was seeded into an alginate with DBP of different contents, and a microcapsule was produced. The adhesion and proliferation of cells was observed through the MTT analysis, and the PCR was applied to estimate the content of the glycosaminoglycan (sGAG) and collagen, and confirm the specific genetic pattern of the chondrocytes. Also, the alginate microcapsule where the chondrocyte is seeded was extracted after transplantation under the skin of a nude mouse, and was immunochemically stained. The experimental result confirmed that the alginate microcapsule containing 1% of DBP not only showed the highest proliferation of cell but had a positive effect of chondrocytes by the interaction between the alginates and the growth factor in DBP. It can be expected that the microcapsule with application of the alginates and DBP might be an appropriate scaffold for tissue engineering.