• Journal of Pharmaceutical Investigation
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• 제40권6호
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• pp.347-351
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• 2010

Isoflavones have received much attention because of their health-related and clinical benefits such as estrogenic and anti-oxidative activities as well as triggering of natural killer cell activity. However, there are few publications reporting the pharmacokinetic profiles together with physicochemical properties of main isoflavones. Therefore, the pharmacokinetic parameters of main aglycones, daidzein, glycitein and genistein after oral administration of soybean extracts were investigated and the physicochemical properties of soybean extracts were characterized. It was observed that angle of repose was $46^{\circ}$ and tap density, bulk density and porosity were 10.12, 4.3 and $0.86\;g/cm^3$ and the mean $AUC_{last}$ of daidzein, glycitein and genistein was $11.376\;{\mu}g{\cdot}h/mL$, $3.045\;{\mu}g{\cdot}h/mL$ and $0.825\;{\mu}g{\cdot}h/mL$, respectively. Cell viability was 60% at a concentration of 10 mg/mL. Taken together, it was suggested that isoflavones were contained in the soybean products and had an antioxidant activity and this study would be the basis to control the quality of soybean products and study of the bioequivalence between soybean products in future.

• 한국전기화학회:학술대회논문집
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• 한국전기화학회 2003년도 연료전지심포지움 2003논문집
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• pp.189-192
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• 2003

In this work, we have prepared platinum catalyst by various methods, investigated fuel cell performance and compared performance with commercially available $20\%$ Pt supported on carbon (Pt/C) catalyst. We have found that Pt/C prepared by reduction of chloroplatinic acid in mixed solvent (water+ethylene glycol) gives better performance compared to that produced by reduction of aqueous chloroplatinic acid, which can be attributed to smaller catalyst particle size and lower agglomeration in the mixed solvent. We have also prepared a novel platinum electrocatalyst by depositing platinum on Nafion coated carbon powder and it shows great promise. The performance of electrode prepared using $20\%Pt$ onn Nafion coated carbon mixed with Pt/C was found to be higher than the performance of electrodes using commercially available $20\%$ Pt/C, up to a current density of about $1100mA/cm^2$. The cell voltages obtained were respectively 621 and 603mV, at a current density of: $1000mA/cm^2$, in a single cell using $0.25mgPt/cm^2$ and Nafion 10035 membrane at $80^{\circ}C$ using hydrogen/oxygen reactants at 1 atm pressure.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제36권3호
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• pp.85-93
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• 2014

Purpose: Nodal metastasis is the main prognostic factor in the patients with oral squamous cell carcinoma (OSCC). We investigated the association between tumor-associated lymphatics and OSCC characteristics. Methods: Thirty-four specimens were used for the immunohistochemical staining with the antibody for vascular endothelial growth factor (VEGF)-C, VEGF-D, VEGF receptor (VEGFR)-3, phosphorylated VEGFR-3, D2-40, and matrix metallproteinases (MMPs). We observed the distribution of the lymphangiogenic factors and quantified the degree of expression. We determined lymphatic vessel density (LVD) and lymphatic vessel dilatation with D2-40 immunostaining. We assessed the association of LVD or lymphatic vessel dilatation with tumor progression or tumor differentiation. Results: OSCC cells expressed lymphangiogenic ligands. Lymphangiogenic receptor, VEGFR-3, was expressed and activated in some tumor cells as well as in tumor-associated endothelial cells. LVD was not associated with tumor size or nodal status, but lymphatic vessel dilatation was higher in tumors with nodal metastasis, and also higher in poorly differentiated tumors. In stromal area of OSCC, MMP-1 and MMP-10 were up-regulated and the basement membrane of tumor-associated endothelial cells was destroyed by these collagenases. Conclusion: In the primary tumors with nodal metastasis, especially in poorly differentiated OSCC, tumor cells invaded the dilated lymphatic vessels via ruptured sites. MMP-1 and MMP-10 are important in the lysis of the glycocalyx inside the tumor-associated lymphatic endothelial cells.

• 한국세라믹학회지
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• 제29권8호
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• pp.587-592
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• 1992

Sheets of SiC-SiC whisker maxed matrix were prepared from the mixed slurry of SiC whisker and SiC matrix by the rolling method. With the increase of SiC whisker, the pore size, the porosity and the phosphoric acid absorbency of the matrix were increased, while the bubble pressure was decreased. The activation energy for the transfer of H+ ion was decreased with the increase of mixing ratio of SiC whisker to the SiC matrix from the measurement of hydrogen ion conductivity. The activation energy was evaluated as 0.25 eV when the mixing ratio of SiC whisker to the SiC matrix was 1 : 2 and the activation energy was 0.16 eV for the 2 : 1 matrix. It means that SiC whisker matrix contributes to attain a better microstructure for the diffusion of hydrogen ion. From the measurement of single cell performance of matrix with various mixing ratio, it is concluded that if SiC-SiC whisker maxed matrix has a sufficient bubble pressure to prevent the crossover of H2 gas, the current density of a fuel cell is increased with the increase of acid absorbency of the matrix. Current density was improved from 140 mA/$\textrm{cm}^2$ for 0.25 mm thickness of matrix to 170 mA/$\textrm{cm}^2$ for the 0.20 mm one at 700 mV.

• 한국세라믹학회지
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• 제52권5호
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• pp.338-343
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• 2015

To prevent an interfacial reaction between the anode and the electrolyte layer during the conventional high-temperature co-firing process, an anode-supported type cell with a thin-film electrolyte was fabricated by low-temperature ceramic thick film coating process. Ni-GDC cermet composite was used as the anode material and YSZ was used as the electrolyte material. Open circuit voltage and maximum power density were found to strongly depend on the surface uniformity of the anode functional layer. By optimizing the microstructure of the anode functional layer, the open circuit voltage and maximum powder density of the cell increased to 1.11 V and $1.35W/cm^2$, respectively, at $750^{\circ}C$. When a GDC barrier layer was applied between the YSZ electrolyte and the LSCF cathode, the cell showed good stability, with almost no degradation up to 100 h. Anode-supported type SOFCs with high performance and good stability were fabricated using a coating process.

• Journal of Microbiology and Biotechnology
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• 제23권1호
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• pp.36-39
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• 2013

We introduce a high-performance microbial fuel cell (MFC) that was operated using a 0.1M bicarbonate buffer as the cathodic electrolyte. The MFC had a 136.42 $mW/m^2$ maximum power density under continuous feeding of 5 mM acetate as fuel. Results of the electrode potential measurements showed that the cathode potential of the bicarbonate-buffered condition was higher than the phosphate-buffered condition, although the phosphate condition had less interfacial resistance between the membrane and electrolyte. Therefore, we posit here that the increased power of the bicarbonate-buffered MFC may be caused by the higher cathode potential rather than by the interfacial membrane-electrolyte resistance.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2006년도 춘계학술대회
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• pp.478-481
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• 2006

Energy is vital to global prosperity, yet dependence on fossil fuels as our primary energy source contributes to global climate change environmental degradation, and health problems. Hydrogen $(H_2)$ offers tremendous potential as a clean renewable energy currency. Hydrogen has the highest gravimetric energy density of any known fuel and is compatible with electrochemical and combustion processes for energy conversion without producing carbon-based emission that contribute to environmental pollution and climate change. Numerous methodologies have been developed for effective hydrogen production. Among them, the biological hydrogen production has gained attention, because hydrogen can be produced by cellular metabolismunder the presence of water and sunlight. The green alga Chlamydomonas reinhardtii is capable of sustained $H_2$ photoproduction when grown under sulfur deprived condition. Under sulfur deprived conditions, PSII and photosynthetic $O_2$ evolution are inactivated, resulting in shift from aerobic to anaerobic condition in the culture. After anaerobiosis, sulfur deprived algal cells induce a reversible hydrogenase and start to evolve $H_2$ gas in the light. According to above principle, we investigated the effect of induction parameters such as cell age, cell density. light intensity, and sulfate concentration under sulfur deprived condition We also developed continuous hydrogen production system by sulfate re-addition under sulfur deprived condition.

• Nuclear Engineering and Technology
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• 제53권4호
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• pp.1284-1288
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• 2021

In this work, we propose and design a GaN-based diode with a p-doped GaN (p-GaN) multi-well structure for high efficiency betavoltaic (BV) cells. The short-circuit current density (J_SC) and opencircuit voltage (V_OC) of the devices were investigated with variations of parameters such as the doping concentration, height, width of the p-GaN well region, well-to-well gap, and number of well regions. The J_SC of the device was significantly improved by a wider depletion area, which was obtained by applying the multi-well structure. The optimized device achieved a higher output power density by 8.6% than that of the conventional diode due to the enhancement of J_SC. The proposed device structure showed a high potential for a high efficiency BV cell candidate.

• 센서학회지
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• 제30권6호
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• pp.364-368
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• 2021

We developed a highly efficient organic photovoltaic (OPV) cell with a poly[4,8-bis(5-(2-ethylhexyl)thiophen-2-yl)benzo[1,2-b;4,5-b']dithiophene-2,6-diyl-alt-(4-(2-ethylhexyl)-3-fluorothieno[3,4-b]thiophene-)-2-carboxylate-2-6-diyl)]:[6,6]-phenyl-C71-butyric acid methyl ester active layer for harvesting lower-intensity indoor light energy to power various self-powered sensor systems that require power in the microwatt range. In order to achieve higher power conversion efficiency (PCE), we first optimized the thickness of the active layer of the OPV cell through optical simulations. Next, we fabricated an OPV cell with optimized active layer thickness. The device exhibited a PCE of 12.23%, open circuit voltage of 0.66 V, short-circuit current density of 97.7 ㎂/cm², and fill factor of 60.53%. Furthermore, the device showed a maximum power density of 45 ㎼/cm², which is suitable for powering a low-power (microwatt range) sensor system.

• Journal of Electrochemical Science and Technology
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• 제15권1호
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• pp.132-151
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• 2024

Proton exchange membrane fuel cell (PEMFC) has received extensive attention as it is the most common hydrogen energy utilization device. This research not only investigated the effect of obstacle number and shape on PEMFC performance, but also studied the effect of the blockage degree in the channel of PEMFC on its performance. It was found that compared with traditional scheme, longitudinally distributed obstacles scheme can significantly promote reactants transfer to catalyst layer, and the blockage degree in the channel effect PEMFC performance most. The scheme with 10 rectangular obstacles in single channel and 60% channel blockage had the best output performance and the most uniform distribution of reactants and products. Obstacle height distribution can significantly affect PEMFC performance, the blockage degree in the whole basin was large, particularly as the channel was blocked to higher degree in region 2 and region 3, higher net power density and better mass transfer effect can be obtained. Among them, the fuel cell with the blockage degree of 40%, 60% and 60% in region 1, region 2 and region 3 have the best PEMFC output performance and mass transfer, the net power density was 29.8% higher than that of traditional scheme.