• Title/Summary/Keyword: Cell density

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Inhibitory Effect of Chlorogenic Acid on Low-Density Lipoprotein Oxidation Induced by Cu ion

  • Jeon, Eun-Raye;Karki, Rajendra;Kim, Dong-Wook
    • Korean Journal of Plant Resources
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    • v.23 no.6
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    • pp.519-525
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    • 2010
  • Chlorogenic acid, formed of an ester of caffeic acid and quinic acid, which is naturally abundant in many plant species, was used as a model O-dihydoxy phenolic compound. In the previous study, we have reported that the isolated constituent from Apocynum venetum leaves has an inhibitory effect on $Cu^{2+}$-induced oxidative modification of low-density lipoprotein (LDL). Among them, chlorogenic acid showed the most potent anti-LDL oxidative activity than other compounds. For the reason, we investigated the inhibitory effect of the chlorogenic acid on $Cu^{2+}$-induced oxidative modification of LDL, monitored a lag time in the conjugated-diene formation and TBARS formation, and measured TNBS free amino acid group, and form cell formation in vitro system. The TBARS- and diene- formation were strongly inhibited by chlorogenic acid ($0{\sim}100\;{\mu}g/ml$) with dose dependent manner. On the other hand, TNBS reactive lysine amino groups on LDL oxidation were protected by chlorogenic acid- treated cell group. Therefore, chlorogenic acid inhibited to cholesterol accumulation in the isolated peritoneal macrophage.

Analysis of 3D Geometry and Compressive Behavior of Aluminum Open Cell Foam Using X-ray Micro CT (마이크로 X-ray CT를 활용한 알루미늄 개방형 폼의 형상 및 압축 거동 분석)

  • Kim, Y.I.;Kim, J.H.;Lee, J.K.;Kim, D.
    • Transactions of Materials Processing
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    • v.20 no.7
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    • pp.518-523
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    • 2011
  • The three dimensional geometries of an aluminum open cell foam before and after uniaxial compressive loading were investigated using the X-ray micro CT(computed tomography). Aluminum 6101-T6 open cell foams of 10, 20, 40 ppi (pore per inch) were considered in this work. After the serial sectioning CT images of aluminum foams were obtained from non-destructive X-ray images, the exact 3D structure were reproduced and visualized with commercial image processing program. The relative density ratio was around the 7.0 to 9.0 range, the unit cells showed anisotropic shapes having the different dimensional ratios of 1.1 to 1.3 between the rise and the transverse directions. The yield stress increased with the relative density ratio and the volumetric strain increased proportionally with compressive strain. The plateau stress in the compressive stress-strain curve was caused by the buckling of ligaments.

Characteristics of Solid Fuel Oxidation in a Molten Carbonate Fuel Cell

  • Lee, Choong-Gon;Kim, Yu-Jeong;Kim, Tae-Kyun;Lee, Sang-Woo
    • Journal of Electrochemical Science and Technology
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    • v.7 no.2
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    • pp.91-96
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    • 2016
  • Oxidation behaviours of ash free coal (AFC), carbon, and H2 fuels were investigated with a coin type molten carbonate fuel cell. Because AFC has no electrical conductivity, its oxidation occurs via gasification to H2 and CO. An interesting behaviour of mass transfer resistance reduction at higher current density was observed. Since the anode reaction has the positive reaction order of H2, CO2 and H2O, the lack of CO2 and H2O from AFC results in a significant mass transfer resistance. However, the anode products of CO2 and H2O at higher current densities raise their partial pressure and mitigate the resistance. The addition of CO2 to AFC reduced the resistance sufficiently, thus the resistance reduction at higher current densities did not appear. Electrochemical impedance results also indicate that the addition of CO2 reduces mass transfer resistance. Carbon and H2 fuels without CO2 and H2O also show similar behaviour to AFC: mass transfer resistance is diminished by raising current density and adding CO2.

AN EXPERIMENTAL STUDY OF THE RADIATION-INDUCED CHANGES ON THE SECRETORY GRANULES OF THE RAT SUBMANDIVULAR GLAND ACINAR CELL (방사선조사가 악하선세포내 분비과립의 미세구조에 미치는 영향에 관한 실험적 연구)

  • Choi Mi;Lee Kang-Sook;Choi Karp-Shik
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.24 no.2
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    • pp.403-410
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    • 1994
  • The purpose of this study was to investigate the irradiation effects on the secretory granules of the rat submandibular gland acinar cell. For this study, Sprague-Dawley strain rats were irradiated to their neck region with the dose of 5Gy and l0Gy by 6MV X-radiation, and sacrificed on the experimental periods after irradiation. The authors observed the ultrastructural changes of the secretory granules of the rat submandibular gland acinar cell under a trasmission electron microscope. The results were as follows: In the transmission electron microscopic examination, secretory granules were blurred in limiting membrane on the 3hours groups after irradiation. And they showed decrease in number, irregularities in shape and distributional pattern, and inhomogeneous internal electron density on the Iday and 3days groups. After then, these changes were recovered in shape and distributional pattern on the 14days groups, and changes of internal electron density and limiting membrane were recovered on the 28days groups after irradiation. Among the intracellular organelles, rough endoplasmic reticulum was scattered, but golgi complex was not changed. And such pathologic changes were earlier and more prominent in 10Gy irradiated groups than in 5Gy irradiated groups.

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The Recovery of Heavy Metals Using Encapsulated Microbial Cells

  • Park, Joong-Kon;Jin, Yong-Biao;Park, Hyung-Woo
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.2 no.2
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    • pp.132-135
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    • 1997
  • We prepared capsules containing Saccharomyces cerevisiae and Zoogloea ramigera cells for the removal of lead(II) and cadmium ions. Microbial cells were encapsulated and cultured in the growth medium. The S.cerevisiae cells grown in the capule did not leak through the capsule membrane. The dried cell density reached to 250 g/l on the basis of the inner volume of the 2.0 mm diameter capsule after 36 hour cultivation. The dry whole cell expolymer density of encapsulated Z.ramigera reached to 200 g/L. The capsule was crosslinked with triethylene tetramine and glutaric dialdehyde solutions. The cadmium uptake of encapsulated whole cell expolymer of Z.ramigera was 55mg Cd/g biosorbent. The adsorption line followed well Langmuir isotherm. The lead uptake of the encapsulated S. cerevisiae was about 30 mg Pb/g biomass. The optimum pH of the lead uptake using encapsulated S. cerevisiae was found to be 6. Freundlich model showed a little better fit to the adsorption data than Langmuir model 95 percent of the lead adsorbed on the encapsulated biosorbents was desorbed by the 1 M HCl solution. The capsule was reused 50 batches without loosing the metal uptake capacity. And the mechanical strength of the crosslinked capsule was retained after 50 trials.

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Effect of Sputtering Conditions for CdTe Thin Films on CdTe/CdS Solar Cell Characteristics (스퍼터링에 의한 CdTe 박막 제조 조건이 CdTe/CdS 태양전지의 특성에 미치는 영향)

  • Jung, Hae-Won;Lee, Cheon;Shin, Jae-Heyg;Shin, Sung-Ho;Park, Kwang-Ja
    • Electrical & Electronic Materials
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    • v.10 no.9
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    • pp.930-937
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    • 1997
  • Polycrystalline CdTe thin films have been studied for photovoltaic application because of their high absorption coefficient and optimal band energy(1.45 eV) for solar energy conversion. In this study CdTe thin films were deposited on CdS(chemical bath deposition)/ITO(indium tin oxide) substrate by rf-magnetron sputtering under various conditions. Structural optical and electrical properties are investigated with XRD UV-Visible spectrophotometer SEM and solar simulator respectively. The fabricated CdTe/CdS solar cell exhibited open circuit voltage( $V_{oc}$ ) of 610 mV short circuit current density( $J_{sc}$ ) of 17.2 mA/c $m^2$and conversion efficiency of about 5% at optimal sputtering conditions.

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Current Research Trends in Microbial Fuel Cell Based on Polymer Electrolyte Membranes (고분자 전해질 분리막 기반 미생물 연료전지의 최근 연구동향)

  • Choi, Tae-Hwan;Kim, Hyo-Won;Park, Ho-Bum
    • Membrane Journal
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    • v.20 no.3
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    • pp.173-184
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    • 2010
  • Microbial fuel cell (MFC) is a promising renewable energy source that can generate electrical energy from organic wastes using microbe. This technology has been regarded as a future green alternative energy in that MFC makes use of organic-rich wastewater and also reduces waste sludges as well as produces electricity. To be practically realized, however, achieving higher power density than now is demanded, which may be possible by eliminating various negative factors to act as resistances in MFC operations. For instance, highly activated microbes, highly conductive electrode materials, and fast electron transfer between microbes and electrodes can lead to MFC with high power density. In particular, polymer electrolyte membranes are also a key component for improved MFC performance.

Effect of Additives on the Densification and Electrical Properties of Ce0.8Gd0.2O2-δ Ceramics (Ceria의 소결과 전기전도도에 미치는 첨가제의 영향)

  • Yoo, Kyung-Bin;Oh, Eun-Ju;Choi, Gyeong-Man
    • Journal of the Korean Ceramic Society
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    • v.42 no.12 s.283
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    • pp.816-820
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    • 2005
  • The doped-ceria is a strong candidate material for an intermediate temperature SOFC. However, the mechanical strength and the magnitude of electrical conductivity need to be increased at low sintering temperature. In this study, to improve both properties, $1at\% $ of Mg, Ca, Cr, Fe, Co, Ni, Cu, Ga, and Zr were added to the GDC20 ($20at\%$ Gd-doped Ceria) and sintered at $1350^{\circ}C$ that is $250^{\circ}C$ lower than $1600^{\circ}C$. With addition, the relative density of the sintered sample increased. Fe, Co, Ni, Cu, Ga doped-GDC20 showed high relative density over $92\%$. Among them, Ga doped-GDC20 showed the most improved sinterability. The conductivity of doped­GDC20 increased by $\~10$ times at $300\~700^{\circ}C$.

Trap Generation Analysis by Program/Erase Speed Measurements in 50 nm Nand Flash Memory (50nm 급 낸드플래시 메모리에서의 Program/Erase 스피드 측정을 통한 트랩 생성 분석)

  • Kim, Byoung-Taek;Kim, Yong-Seok;Hur, Sung-Hoi;Yoo, Jang-Min;Roh, Yong-Han
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.21 no.4
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    • pp.300-304
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    • 2008
  • A novel characterization method was investigated to estimate the trap generation during the program /erase cycles in nand flash memory cell. Utilizing Fowler-Nordheim tunneling current, floating gate potential and oxide electric field, we established a quantitative model which allows the knowledge of threshold voltage (Vth) as a function of either program or erase operation time. Based on our model, the derived results proved that interface trap density (Nit) term is only included in the program operation equation, while both Nit and oxide trap density (Not) term are included in the erase operation equation. The effectiveness of our model was tested using 50 nm nand flash memory cell with floating gate type. Nit and Not were extracted through the analysis of Program/Erase speed with respect to the endurance cycle. Trap generation and cycle numbers showed the power dependency. Finally, with the measurement of the experiment concerning the variation of cell Vth with respect to program/erase cycles, we obtained the novel quantitative model which shows similar results of relationship between experimental values and extracted ones.

Squamous Cell Carcinoma in an African Pigmy Hedgehog (Atelerix Albiventris) (아프리카 피그미 고슴도치에서 발생한 편평상피세포암종)

  • Kim, Wan-Hee;Kim, Bang-Hyun;Park, Woo-Ram;Chang, Dong-Woo;Jeong, Seong-Mok;Yoon, Jung-Hee;Kim, Dae-Yong;Nam, Tchi-Chou
    • Korean Journal of Veterinary Pathology
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    • v.5 no.1
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    • pp.1-4
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    • 2001
  • Squamous cell carcinoma was diagnosed in a 4.5-year-old male African hedgehog (Atelerix albiventris). The patient was referred to Seoul National University, Veterinary Medical Teaching Hospital after 5 days history of left eye exophthalmos and corneal trauma. He had enlarged upper and lower jaw at the left part of the face and endophthalmitis of the left eye. On radiographic examinations, loss of bone density at the left zygomatic arch and sun-burst type periosteal reaction of left mandible with decreased bone density was noted. Histologically, the neoplastic mass consisted of markedly invasive, cords of nests of squamous epithelial cells. Intercellular bridges and keratin pearl formation were also noted.

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