• 한국지리정보학회지
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• 제23권4호
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• pp.16-41
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• 2020

실제 공간의 분포 또는 양적 속성을 대변하는 지리정보 입력은 지구시스템 모의 내에서 주요 관심사가 되고 있다. 많은 연구에서 다양한 격자 해상도에서의 지표면 특성에 대한 부정확한 추정이 모델링 결과를 크게 바꾸는 것으로 나타났다. 따라서, 이 논문은 도시지역 건물들의 분포와 면적·체적 속성을 반영하기 위해서, 항공라이다로 수집된 3DPC(three-dimensional point cloud) 샘플링 체계에 Monte Carlo Integration(MCI) 기법 기반 공간확률(spatial probability)을 적용을 제안하였다. 건물 식별과 관련해 공간확률(SP) 임계치, 격자 크기, 3차원점군 밀도 세 인자의 결정규칙 적용 결과가 비교되었다. 연구 결과, 건물의 격자가 커짐에 따라 식별되는 건물의 면적 속성이 증가하였다. 공간 모델링 및 분석의 신뢰성을 높이기 위해서는 샘플링 체계에서의 결정규칙을 사용하여 건물의 면적 속성을 조정하는 것이 권장된다. 제안된 방법은 모델링 분야가 요구하는 크고 작은 격자의 변화에서도 일정하게 건물 면적 속성이 유지되도록 지원할 것이다.

• 한국동물생명공학회지
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• 제36권2호
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• pp.91-98
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• 2021

The objective of this study was to establish a selection process for high quality sperm in bovine semen using sperm separation by magnetic activation (MACS). For this, semen from 21 Nellore bulls was collected using an artificial vagina. To guarantee the presence of pathologies in the ejaculate, animals previously declassified in four consecutive spermiogram were used. Semen was analyzed in five statuses: (1) fresh semen (fresh); (2) density gradient centrifugation (DGC), percoll column; (3) non-apoptotic fraction after separation by MACS (MAC); (4) apoptotic fraction from the separation (MACPOOR); and (5) MAC followed by DGC (MACDGC). Using a computerized analysis system (CASA), motility was measured. The sperm morphology was evaluated by phase contrast, and the supravital test was completed with eosin/nigrosin staining. For DGC, 20 × 10⁶ cells were used in a gradient of 90% and 45% percoll. MACS used 10 × 10⁶ cells with 20 μL of nanoparticles attached to annexin V, and filtered through the MiniMACS magnetic separation column. Membrane integrity was assessed with SYBR-14/IP and mitochondrial potential with JC-1 by flow cytometry. Processing sperm by MACDGC, was more effective in obtaining samples with high quality sperm, verified by the total of abnormalities in the samples: 35.04 ± 2.29%, 21.50 ± 1.47%, 17.30 ± 1.10%, 30.68 ± 1.94% and 10.50 ± 1.46%, respectively for fresh, DGC, MAC, MACPOOR, and MACDGC. The subpopulation of non-apoptotic sperm had a high number of live cells (82.65%), membrane integrity (56.60%) and mitochondrial potential (83.98%) (p < 0.05). These findings suggest that this nanotechnological method, that uses nanoparticles, is efficient in the production of high-quality semen samples for assisted reproduction procedures in cattle.

• 방사성폐기물학회지
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• 제19권4호
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• pp.459-467
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• 2021

In the majority of countries, the upper limit of buffer temperature in a repository is set to below 100℃ due to the possible illitization. This smectite-to-illite transformation is expected to be detrimental to the swelling functions of the buffer. However, if the upper limit is increased while preventing illitization, the disposal density and cost-effectiveness for the repository will dramatically increase. Thus, understanding the characteristics and creating a database related to the buffer under the elevated temperature conditions is crucial. In this study, a strategy to investigate the bentonite found in Korea under the elevated temperatures from a mineral transformation and radionuclides retardation perspective was proposed. Certain long-term hydrothermal reactions generated the bentonite samples that were utilized for the investigation of their mineral transformation and radionuclide retardation characteristics. The bentonite samples are expected to be studied using in-situ synchrotron-based X-Ray Diffraction (XRD) technique to determine the smectite-to-illite transformation. Simultaneously, the 'high-temperature and high-pressure mineral alteration measurement system' based on the Diamond Anvil Cell (DAC) will control and provide the elevated temperature and pressure conditions during the measurements. The kinetic models, including the Huang and Cuadros model, are expected to predict the time and manner in which the illitization will become detrimental to the performance and safety of the repository. The sorption reactions planned for the bentonite samples to evaluate the effects on retardation will provide the information required to expand the current knowledge of repository optimization.

• Journal of Microbiology and Biotechnology
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• 제32권6호
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• pp.730-739
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• 2022

Methicillin-resistant Staphylococcus aureus (MRSA) causes severe infections and poses a global healthcare challenge. The utilization of novel molecules which confer synergistical effects to existing MRSA-directed antibiotics is one of the well-accepted strategies in lieu of de novo development of new antibiotics. Thymol is a key component of the essential oil of plants in the Thymus and Origanum genera. Despite the absence of antimicrobial potency, thymol is known to inhibit MRSA biofilm formation. However, the anti-MRSA activity of thymol analogs is not well characterized. Here, we assessed the antimicrobial activity of several thymol derivatives and found that 4-chloro-2-isopropyl-5-methylphenol (chlorothymol) has antimicrobial activity against MRSA and in addition it also prevents biofilm formation. Chlorothymol inhibited staphyloxanthin production, slowed MRSA motility, and altered bacterial cell density and size. This compound also showed a synergistic antimicrobial activity with oxacillin against highly resistant S. aureus clinical isolates and biofilms associated with these isolates. Our results demonstrate that chlorinated thymol derivatives should be considered as a new lead compound in anti-MRSA therapeutics.

• Steel and Composite Structures
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• 제43권5호
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• pp.581-601
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• 2022

The main objective of this research work is to investigate the free vibration behavior of annular sandwich plates resting on the Kerr foundation at thermal conditions. This sandwich configuration is composed of two FGM face sheets as coating layer and a porous GPLRC (GPL reinforced composite) core. It is supposed that the GPL nanofillers and the porosity coefficient vary continuously along the core thickness direction. To model closed-cell FG porous material reinforced with GPLs, Halpin-Tsai micromechanical modeling in conjunction with Gaussian-Random field scheme is used, while the Poisson's ratio and density are computed by the rule of mixtures. Besides, the material properties of two FGM face sheets change continuously through the thickness according to the power-law distribution. To capture fundamental frequencies of the annular sandwich plate resting on the Kerr foundation in a thermal environment, the analysis procedure is with the aid of Reddy's shear-deformation plate theory based high-order shear deformation plate theory (HSDT) to derive and solve the equations of motion and boundary conditions. The governing equations together with related boundary conditions are discretized using the generalized differential quadrature (GDQ) method in the spatial domain. Numerical results are compared with those published in the literature to examine the accuracy and validity of the present approach. A parametric solution for temperature variation across the thickness of the sandwich plate is employed taking into account the thermal conductivity, the inhomogeneity parameter, and the sandwich schemes. The numerical results indicate the influence of volume fraction index, GPLs volume fraction, porosity coefficient, three independent coefficients of Kerr elastic foundation, and temperature difference on the free vibration behavior of annular sandwich plate. This study provides essential information to engineers seeking innovative ways to promote composite structures in a practical way.

• Nutrition Research and Practice
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• 제15권3호
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• pp.319-328
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• 2021

BACKGROUND/OBJECTIVES: Curcuma zedoaria R. (Zingiberaceae) has been used to treat headache, fever, and hypertension-related symptoms in Asian countries, including Korea, China, and Japan. We investigated whether dietary intake of a C. zedoaria extract (CzE) affected atherosclerosis in vivo. MATERIALS/METHODS: Apolipoprotein E-deficient (ApoE^-/-) mice (n = 32) were fed a normal diet (ND), a high-cholesterol diet (HCD), an HCD containing CzE (100 mg/kg/day), or an HCD containing simvastatin (10 mg/kg/day) for 12 weeks. The anti-atherosclerotic effects were evaluated by observing changes in fatty streak lesions, immunohistochemical analysis, ex vivo fluorescence imaging, lipid profiles, and western blot analysis. RESULTS: The CzE-fed group showed a 41.6% reduction of atherosclerosis. Furthermore, CzE significantly reduced the levels of serum triglyceride, high-density lipoprotein, the chemokine (C-X3-C-motif ) ligand 1, the adhesion molecules vascular cell adhesion molecule-1, intracellular adhesion molecule-1, and E-selectin; down-regulation of tumor necrosis factor-α, interleukin-6, high mobility group box-1, and cathepsin levels in the aortic sinuses and aortas of ApoE^-/- mice were also observed. CONCLUSIONS: The results suggest that the inclusion of a water extract of C. zedoaria in a HCD is closely correlated with reducing the risk of vascular inflammatory diseases in an ApoE mouse model.

• Journal of Electrochemical Science and Technology
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• 제12권2호
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• pp.246-256
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• 2021

Mo,Cu-doped CeO₂ (CMCuO) nanopowders were synthesized by the nitrate-fuel combustion method aiming to improve the electrical and electrochemical properties of its Mo-doped CeO₂ (CMO) parent by the addition of copper. An electrical conductivity of ca. 1.22·10^-2 S cm^-1 was measured in air at 800℃ for CMCuO, which is nearly 10 times higher than that reported for CMO. This increase was associated with the inclusion of copper into the crystal lattice of ceria and the presence of Cu and Cu₂O as secondary phases in the CMCuO structure, which also could explain the increase in the charge transfer activities of the CMCuO based anode for the hydrogen and carbon monoxide electro-oxidation processes compared to the CMO based anode. A maximum power density of ca. 120 mW cm^-2 was measured using a CMCuO based anode in a solid oxide fuel cell (SOFC) with YSZ electrolyte and LSM-YSZ cathode operating at 800℃ with humidified syngas as fuel, which is comparable to the power output reported for other SOFCs with anodes containing copper. An increase in the area specific resistance of the SOFC was observed after ca. 10 hours of operation under cycling open circuit voltage and polarization conditions, which was attributed to the anode delamination caused by the reduction of the Cu₂O secondary phase contained in its microstructure. Therefore, the addition of a more electroactive phase for hydrogen oxidation is suggested to confer long-term stability to the CMCuO based anode.

• Journal of the Korean Wood Science and Technology
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• 제30권2호
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• pp.102-107
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• 2002

본 연구는 낙엽송(Larix Kaemferi Carr.)재를 이용하여 100℃부터 180℃까지의 고온영역에서 20℃ 간격으로 처리시간을 10분, 30분, 60분, 90분간으로 하여 처리조는 봄베를 사용하였다. 1) 고온수증기처리의 처리시간이 길고, 처리온도가 높을수록 밀도의 감소도 커졌다. 2) 밀도의 감소에도 불구하고 고온수증기처리재의 수축율이 control재와 비교하여 비슷하거나 높게 나타나는 것은 수증기처리에 의하여 세포벽 내부의 구성성분 및 구조변화에 의하여 야기된 것으로 판단된다. 3) 고온수증기처리에 의하여 추정목재의 틀어짐은 감소되었다.

• Journal of the Korean Wood Science and Technology
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• 제30권4호
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• pp.1-7
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• 2002

본 연구에서는 낙엽송재(Larix Kaemferi Carr.)를 대상으로 100℃부터 130℃까지의 고온영역에서 10℃ 간격으로 처리시간을 10분, 30분, 60분간으로 하여 수증기처리 후 처리재의 물리적 특성 등을 검토하였으며, 오토클레이브를 사용 처리하였다. 휨강도와 압축강도는 처리온도의 증가에 따라 약간씩 감소하는 것으로 나타났다. 그러나 수증기처리한 목재강도와 처리온도 사이에는 명확한 결과가 나타나지 않았다. 120℃에서 130℃의 온도범위에서 세포벽 내의 성분과 조직이 변화하는 것으로 생각되는데, 이것은 응력의 해소에서 기인되는 것으로 생각되었다. 수분흡수성은 고온수증기처리조건에 의한 변화가 없는 것으로 나타났다. 결론적으로 본 실험의 범위에 있어서 목재의 물성은 처리 온도조건보다는 목재밀도의 영향을 많이 받고 있는 것으로 판단되었다.

• 한국염색가공학회지
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• 제33권4호
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• pp.317-326
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• 2021

In this study, we investigated for Bio-EPDM foam with oyster shell surface modified earth coupling agent. Experiments were carried out to confirm the bio-EPDM/Oyster shell foam applying content of earth coupling agent. The cure characterization were evaluated by measuring the mooney viscosity and oscillating disc rheometer (ODR). Mechanical properties such as hardness, tensile strength, elogation at break and tear strength were measured, and changes of mechanical properties were also evaluated after immersion in NaCl solution. In addition degree of volume change was measured after immersing the Bio-EPDM foam in NaCl solution and the low-temperature permanent compression set was evaluated at 4℃. To evaluate the low-temperature characteristics of Bio-EPDM/Oyster shell, the glass transition temperature was measured using Differential Scanning Calorimeter (DSC). As a result as the content of the earth coupling agent increased up to 3phr, the crosslinking density and mooney viscosity increased, and the mechanical properties and low-temperature permanent compression set improved, but from 4phr, it was rather decreased. The change in the glass transition temperature was insignificant, and the foam cell appeared to be uniform when the earth coupling agent was applied.