• 동의생리병리학회지
• /
• 제19권3호
• /
• pp.618-622
• /
• 2005

Articular cartilage is an important target for studying the arthritic diseases. To verify the therapeutic effects of bee venom herb-acupuncture in vivo, 3${\mu}$l of diluted solution of bee venom for herb-acupuncture were injected into articular cavity once a day during 3 months after making full-thickness defects in rat articular cartilage. Histological examination and immunohistochemistry indicated that the chondrocyte-like tissue was formed during the repair process of cartilage injury, and the expression of a cartilage-specific protein, collagen type II, were significantly activated. It means that the expression of the gene encoding type I collagen was down-regulated, whereas those of collagen type II were up-regulated. Histological examination by hematoxylin-eosin staining indicated that the cells regained their original round morphology. In addition, a homogeneous distribution of articular cartilage extracellular matrices was detected around the cells. These results suggested that bee venom herb-acupuncture was very effective on the recovery of articular chondrocyte phenotype.

• Imaging Science in Dentistry
• /
• 제42권4호
• /
• pp.219-224
• /
• 2012

Purpose: This study investigated the relationship between the roots of the maxillary molars and the maxillary sinus using cone beam computed tomography (CBCT), and measured the distances between the roots of the maxillary molars and the sinus floor as well as the thickness of the bone between the root and the alveolar cortical plate. Materials and Methods: The study sample consisted of 83 patients with normally erupted bilateral maxillary first and second molars. A total of 332 maxillary molars were examined using CBCT images. The vertical relationship of each root with the maxillary sinus was classified into four types on CBCT cross-sectional images. The distance between the sinus floor and root and the bone thickness between the root and alveolar cortical plate were measured. Results: In the buccal roots of the maxillary molars, a root protruding into the sinus occurred most frequently. A root projecting laterally along the sinus cavity was most common in the palatal roots of the maxillary first molars. The mesiobuccal roots of the maxillary second molar were closest to the sinus. The mesiobuccal roots of the first molars were closest to the cortical plate. Conclusion: The relationship between the roots of the maxillary molars and the sinus differed between the buccal and palatal roots. A root protruding into the sinus occurred more frequent in the buccal roots of the maxillary molars. The mesiobuccal root of the maxillary second molar was closest to the maxillary sinus floor and farthest from the alveolar cortical plate.

• KIEE International Transactions on Electrophysics and Applications
• /
• 제4C권4호
• /
• pp.137-141
• /
• 2004

In this paper, a thermopneumatic PMDS (polydimethlysiloxane) micropump with nozzle/diffuser elements is presented. The micropump is composed of nozzle/diffuser elements as dynamic valves, an actuator consisting of a circular PDMS diaphragm and a Cr/Au heater on a glass substrate. Four PDMS layers are used for fabrication of an actuator chamber, actuator diaphragm by a spin coating process, spacer layer, and nozzle/diffuser by the SU-8 molding process. The radius and thickness of the actuator diaphragm is 2 mm and 30 ${\mu}{\textrm}{m}$, respectively. The length and the conical angle of the nozzle/diffuser elements are 3.5 mm and 20$^{\circ}$, respectively. The actuator diaphragm is driven by the air cavity pressure variation caused by ohmic heating and natural cooling. The flow rate of the micropump in the frequency domain is measured for various duty cycles of the square wave input voltage. When the square wave input voltage of 5 V DC is applied to the heater, the maximum flow rate of the micropump is 44.6 ${mu}ell$/min at 100 Hz with a duty ratio of 80% under the zero pressure difference.

• Restorative Dentistry and Endodontics
• /
• 제39권2호
• /
• pp.120-125
• /
• 2014

Use of an apical plug in management of cases with open apices has gained popularity in recent years. Biodentine, a new calcium silicate-based material has recently been introduced as a dentine substitute, whenever original dentine is damaged. This case report describes single visit apexification in a maxillary central incisor with necrotic pulp and open apex using Biodentine as an apical barrier, and a synthetic collagen material as an internal matrix. Following canal cleaning and shaping, calcium hydroxide was placed as an intracanal medicament for 1 mon. This was followed by placement of small piece of absorbable collagen membrane beyond the root apex to serve as matrix. An apical plug of Biodentine of 5 mm thickness was placed against the matrix using pre-fitted hand pluggers. The remainder of canal was back-filled with thermoplasticized gutta-percha and access cavity was restored with composite resin followed by all-ceramic crown. One year follow-up revealed restored aesthetics and function, absence of clinical signs and symptoms, resolution of periapical rarefaction, and a thin layer of calcific tissue formed apical to the Biodentine barrier. The positive clinical outcome in this case is encouraging for the use of Biodentine as an apical plug in single visit apexification procedures.

• 동아시아식생활학회지
• /
• 제8권2호
• /
• pp.116-125
• /
• 1998

This study was designed to find out the anti-cancer effects of two herbs using a folk remedy in Korea-The two herbs were A: Equisetum arvense L. (Seddugi), B: Eunymus alatus Siebold. (Hwasalnamoo) The experiment for the anti-cancer effects were conducted in mice and experimental groups were divided into normal(NO), standard (ST) and two other(A,B) groups for each herb and each of the two experimental groups consisted of three sub-groups(I, II, III) according to three different quantity doses of a folk remedy using five times and ten times the quantity of a commonly used in a folk remedy. The water soluble extracts of two herbs were orally administered to mice during six weeks followed by inoculation of the sarcoma-180 tumor cells into the peritoneal cavity. During experimental periods, the contents of ascites, abdominal organs were observed histopathologically. The results of effects on anticancer were as follows : 1. The survival time was significantly prolonged by the two herbs, especially in groups AII & BII.2. Body weight, circumference of the abdomen and contents of ascites at the time of sacrifice were noted and significantly decreased in groups AI, AII & BII. 3. Anti-cancer effects evaluated by the invasiveness and thickness of the tumor cells were noted in groups AIII & BII.

• Applied Microscopy
• /
• 제28권3호
• /
• pp.329-343
• /
• 1998

Early wound healing responses in the skin of the Korean fire bellied toad, Bombina orientalis, were examined using histochemical , scanning and transmission electron microscopical techniques. Cutaneous wounds were induced by sharp razor blade , and maintained in special cages for up to 3 days. By this treatment whole parts of epithelium and dermis were profoundly affected. After injury, retraction of damaged surface of the skin was observed. At 3 hours after injury, poly-band was form by mucous substance. The wound skin consisted of mucous gland secreted mucous substance which flows into wound cavity and the wound area was sealed by mucous substance which form thick layer at 6 hours. It appeared that natural disposition showed acid and neutral mucous substance by reaction of PAS and Alcian blue (pH 2.5) staining. After formation of the poly-band, epithelial cells were formed by migration of regenerating epithelial cells. These cells moved over the wound surface by migration at 12 hours after wounding. Poly-band was much increased in thickness and migrating cells were completely formed wound closure at 24 hours post-wounding. After 72 hours regenerated epithelial layer consists of four or five cell layers which are similar to clear, granular, and spinous layer.

• 대한기계학회논문집B
• /
• 제21권2호
• /
• pp.329-340
• /
• 1997

A passive control of interaction of condensation shock wave / boundary layer for reducing the strength of condensation shock was conducted experimentally in a 2.5 * 8 cm$^{2}$ indraft type supersonic wind tunnel. The effects of following factors on passive control were investigated: 1) the thickness of porous wall, 2) the diameter of porous hole, and 3) the orientation of porous hole. On the other hand, the location of nonequilibrium condensation region and condensation shock wave was controlled by regulation of the stagnation conditions. Surface static pressure measurements as well as Schlieren observations of the flow field were obtained, and their effects were compared with the results the cases of without passive control. It was found that thinner porous wall, smaller porous hole and FFH orientation for the same cavity size and porosity of 12% are more favourable than the cases of its opposite.

• International Journal of Precision Engineering and Manufacturing
• /
• 제2권2호
• /
• pp.38-47
• /
• 2001

This paper decribes the development of computer-aided design of a very precise progressice die for lead frame of semiconductor chip. The approach to the system is based on knowledgr-based rules. Knowledge of fie이 experts. This system has been written in AutoLISP using AutoCAD ona personal computer and the I-DEAS drafting programming Language on the I-DEAS mater series drafting with on HP9000/715(64) workstation. Data exchange between AutoCAD and I-DEAS master series drafting is accomplished using DXF(drawing exchange format) and IGES(initial graphics exchange specification) files. This system is composed of six main modules, which are input and shape treatment, production feasibility check, strip layout, data conversion, die layout, and post processing modules. Based on Knowledge-based rules, the system considers several factors, such as V-notches, dimple, pad chamfer, spank, cavity punch, camber, coined area, cross bow, material and thickness of product, complexities of blank geometry and punch profiles, specifications of available presses, and the availability of standard parts. As forming processes and the die design system using 2D geometry recognition are integrated with the technology of process planning, die design, and CAE analysis, the standardization of die part for lead frames requiting a high precision process is possible. The die layout drawing generated by the die layout module s displayed in graphic form. The developed system makes it possible to design and manufacture lead frame of a semiconductor more efficiently.

• 한국원자력학회:학술대회논문집
• /
• 한국원자력학회 1997년도 춘계학술발표회논문집(1)
• /
• pp.362-367
• /
• 1997

To assess the coolability of particle bed, which is formed in reactor cavity, it is important to assess the prediction capabilities of Dryout Heat flux correlations. The existing DHF correlations (Sowa et al., Dhir-Catton (a), Dhir-Catton (b), Hardee-Nilson, Ostesen, Shires-Stevens, Lipinski, Jones et al., Dhir-Barleon, Theofanous-Saito, Henry-Fauske) for particle beds are assessed using developed DHF database. Eleven DHF correlations are chosen for assessment based on literature survey. Among them, five are based on flooding correlation, which are used for chemical engineering and others are based on conservation equations. The parameters in DHF correlations are directly substituted into correlations. Totally 202 data are classified into 6 groups based on bed thickness and particle diameter. In each group, prediction capabilities of correlations are assessed and shown by standard deviation and root mean square (RMS) error. Prediction capability of each correlation depends on the data group and none of correlations shows best prediction capability on entire groups. According to present study, even if those correlations show poor prediction capability, Lipinski correlation is best correlation considering entire groups.

• 한국추진공학회:학술대회논문집
• /
• 한국추진공학회 2006년도 제26회 춘계학술대회논문집
• /
• pp.306-309
• /
• 2006

슬롯을 이용한 충격파와 난류 경계층의 간섭유동의 피동제어에 관한 연구가 이루어졌다. 슬롯의 다양한 형상 변화가 간섭유동에 미치는 영향이 관찰되었으며, 이를 위하여 간섭유동 후방에서 피토/벽압력 분포 및 쉴리렌, 오일막 간섭 줄무늬 형상과 같은 유동가시화 정보 등이 얻어졌다. 특정한 슬롯적용의 경우, 충격파를 통한 전압손실의 감소가 관찰되었으나 경계층의 두께는 두꺼워지는 것으로 나타났다.