• Restorative Dentistry and Endodontics
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• v.15 no.1
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• pp.1-15
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• 1990

The aim of this study was to investigate the effect of dental therapeutic agent on conduction velocity and threshold current of intradental A- and C-fibers in the cat. Inferior alveolar nerve of cat anesthetized with sodium pentobarbital was exposed and dissected until response of functional single pulp nerve until could be evoked by monopolar electrical stimulation of the crown of the lower left canine teeth. 10ms rectangular pulse was used to determine the threshold current and 1ms rectangular pulse was used to determine conduction velocity. After application of calcium chloride (1, 2, 6M), calcium hydroxide mixed with saline, potassium chloride (0.2, 0.8, 1.6M), eugenol, zinc oxide eugenol to the cavity on the labial surface, conduction velocity and threshold current of single pulp nerve unit were compared with the control. In 10 cats, 24 $A{\delta}$- and 11 C- pulp nerve units were recorded. The mean conduction velocities of $A{\delta}$- and C-fibers were 7.5m/sec (SD=5.8) and 1.2m/sec (SD=0.4), respectively. The mean threshold current was $12.3{\mu}A$ (SD=5.3) for $A{\delta}$-fibers and $24.9{\mu}A$ (SD=8.1) for C-fibers. 1, 2, 6M calcium chloride caused decrease of conduction velocity and remarkable increase of threshold current in $A{\delta}$- and C-fibers. The effect of calcium hydroxide mixed with saline was similar but smaller than calcium chloride solution. 0.2M potassium chloride had insignificant effect. In 0.8M potassium chloride, the threshold current was increased although conduction velocity was not affected. In 1.6M potassium chloride, the threshold current was increased and the conduction velocity was slowed down. Spontaneous activity was recorded frequently for first 5 min but gradually reduced both in $A{\delta}$- and C-fibers. Eugenol had irreversible effect on pulp nerve in that initially there were not certain changes in the conduction velocity and threshold current of $A{\delta}$- and C-fibers, but the responses to electrical stimulation were abruptly disappeared after sustained application and were not recovered. Contrary to eugenol, zinc oxide eugenol did not caused significant increase of the threhold current and caused time dependent decrease of the conduction velocity, and did not show any irreversible change.

• Restorative Dentistry and Endodontics
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• v.30 no.5
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• pp.363-371
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• 2005

This study investigated the effect of thickness of flowable resin lining on marginal leakage in class II composite restorations. 80 experimental teeth were prepared with class II preparations with enamel margin or dentin margin. Each group was devided into four groups according to flowable resin lining thickness ; Control group - no flowable resin lining, Group 1 - 0.5 mm flowable resin lining, Group 2 - 1 mm flowable resin lining, Group 3 - 2 mm flowable resin lining. The cavities were restored using Scotchbond Multi-Purpose adhesive system, Filtek Flow and Filtek Z 250 composite resin. Following one day storage in distilled water, the restored teeth were thermocycled for 500 cycles and immersed in $2\%$ methylene blue for 24 hours. The results of this study were as follows : 1. Ranking of mean microleakage scores at the enamel margins was Group 1 < Control = Group 2 < Group 3. The microleakage of Group 3 was significantly higher than that of Control, Group 1 and Group 2 (p < 0.05). 2. Ranking of mean microleakage scores at the dentin margins was Group 1 < Group 2 < Control < Group 3. The microleakage of Group 3 was significantly higher than that of Control, Group 1 (p < 0.05) 3. Compared with microleakage between the enamel and dentin margins, enamel margin group were significantly lower than dentin margin group.

• Restorative Dentistry and Endodontics
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• v.30 no.5
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• pp.355-362
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• 2005

The purpose of this study was to compare the effect on marginal leakage of a resin surface sealant (Biscover) applied before or after polymerization of composite resin to unsealed composite restorations. Thirty Class V cavities with the occlusal margin in enamel and cervical margin in dentin or cementum were prepared on the buccal surfaces of sound extracted molars and restored with a microfilled light-cured composite resin (Micronew). Restorations were randomly assigned into one of three equal groups (n = 10): a control group - no surface sealing, group 1 - applied Biscover after polymerization of the composite resin. and group 2 - applied Biscover before polymerization of the composite resin. Specimens were thermocycled, immersed in a $20\%$ methylene blue solution for 4 hoots, sectioned longitudinally, and analyzed for leakage at the occlusal and gingival margins. The results of this study were as follows 1. In sealed group, group 2 showed higher microleakage than group 1 at both occlusal and gingival margins. but there was no significant difference between two groups (p > 0.05). 2. Unsealed control group showed a little higher microleakage than sealed group at occlusal margins, and a little Higher or similar microleakage than sealed group at gingival margins (p > 0.05) 3. Control group and group 2 showed significantly less microleakage at the occlusal margins, but group 1 showed no significantly difference between microleakage at the occlusal and gingival margins.

• Restorative Dentistry and Endodontics
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• v.28 no.2
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• pp.134-145
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• 2003

Mechanical properties and microleakage of two composites [conventional hybrid type DenFil (VERICOM Co., Anyang, Korea) / micro matrix hybrid type Esthet X (Dentsply Caulk, Milford, DE, U.S.A.)] were evaluated to assess whether variable light intensity curing is better than conventional curing technique. Curing was done for 40 seconds in two ways of 2 step soft-start technique and 5 step ramping technique. Three kinds of light intensities of 50, 100, $200{\;}mW/\textrm{cm}^2$ were initially used for 10, 20, 30 seconds each and the maximum intensity of $600 {\;}mW/\textrm{cm}^2$ was used for the rest of curing time in a soft-start curing tech nique. In a ramping technique, curing was done with the same initial intensities and the light intensity was increased 5 times with the same rate to the maximum intensity of $600{\;}mW/\textrm{cm}^2$. After determining conditions that showed no different mechanical properties with conventional technique, Esthet X composite was filled in a class V cavity, which dimension was $4{\times}3{\times}1.5{\;}mm$ and cured under those conditions. Microleakage was evaluated in two ways of dye penetration and maximum gap estimation through SEM observation. ANOVA and Spearman's rho test were used to confirm any statistical significance among groups. The results were as follows : 1 Several curing conditions of variable light intensities resulted in the similar mechanical properties with a conventional continuous curing technique, except conditions that start curing with an initial light intensity of $50{\;}mW/\textrm{cm}^2$. 2. Conventional and ramping techniques were better than soft-start technique in mechanical properties of microhardness and compressive strength. 3. Soft-start group that started curing with an initial light intensity of $100{\;}mW/\textrm{cm}^2$ for 10 seconds showed the least dye penetration. Soft-start group that started curing with an initial light intensity of $200{\;}mW/\textrm{cm}^2$ for 10 seconds showed the smallest marginal gap, if there was no difference among groups. 4. Soft-start technique resulted in better dye-proof margin than conventional technique(p=0.014) and ramping technique(p = 0.002). 5. There was a very low relationship(p=0.157) between the methods of dye penetration and marginal gap determination through SEM evaluation. From the results of this study, it was revealed that ramping technique would be better than conventional technique in mechanical properties, however, soft-start technique might be better than conventional one in microleakage. It was concluded that much endeavor should be made to find out the curing conditions, which have advantages of both aspects or to solve these kinds of problems through a novel idea of polymerization.

• Restorative Dentistry and Endodontics
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• v.33 no.3
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• pp.184-197
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• 2008

This study was to investigate the influence of combining composite resins with different elastic modulus, and occlusal loading condition on the stress distribution of restored notch-shaped non-carious cervical lesion using 3D finite element (FE) analysis. The extracted maxillary second premolar was scanned serially with Micro-CT. The 3D images were processed by 3D-DOCTOR. ANSYS was used to mesh and analyze 3D FE model. A notch-shaped cavity was modeled and filled with hybrid, flowable resin or a combination of both. After restoration, a static load of 500N was applied in a point-load condition at buccal cusp and palatal cusp. The stress data were analyzed using analysis of principal stress. Results showed that combining method such that apex was restored by material with high elastic modulus and the occlusal and cervical cavosurface margin by small amount of material with low elastic modulus was the most profitable method in the view of tensile stress that was considered as the dominant factor jeopardizing the restoration durability and promoting the lesion progression.

• Journal of Ginseng Research
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• v.23 no.3 s.55
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• pp.182-189
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• 1999

For the determination of anti oxidative effects of Korean red ginseng extracts, 100 mg/kg body weight of paraquat(1,1-dimethyl-4,4-bipyrimidinium dichloride) was injected to peritoneal cavity of 6 weeks 23-27 g of ICR mail mice which were pretreated with 200 mg/kg body weight of korean red ginseng extracts(total saponin, water extracts, alcohol extracts, lipophilic extracts) and ascorbic acid for 5 days. Most of mice died of paraquat toxicity within 4 days except only $30\%$ of ascorbic acid group. The hepatic total-SOD activity in liver was highest in ascorbic acid group and lipophilic ginseng extracts group next (p<0.0l). The level of hepatic hydroperoxide was lowest in the order of in alcohol extracts group, lipophilic extracts group and ascorbic acid group (p<0.0l). The highest catalase activity was induced by ascorbic acid followed by water extracts and lipophillic extracts (p<0.01). Finally, the lipid peroxidation level (malondialdehyde:MDA) was the lowest in water extracts group and ascorbic acid next (p<0.01). The highest MDA level was appeared in praquat group and next total saponin group next. In conclusion, the order of effectiveness of antioxidants was found to be ginseng water extracts> ascorbic acid> lipophillic extracts> other ginseng extracts. It was also found that any predominant antioxidant was not effective evenly to all of antioxidant test.

• Bulletin of the Korean Chemical Society
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• v.23 no.8
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• pp.1121-1126
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• 2002

Two anhydrous crystal structures of fully dehydrated Cd2+ - and Cs+ -exchanged zeolite X, Cd32Cs28Si100Al92O384 (Cd32Cs28-X: a = 24.828(11) $\AA)$ and fully dehydrated Cd,sup>2+ - and Rb+ -exchanged zeolite X, Cd28Rb36Si100Al92O384 (Cd28Rb36-X: a = 24.794(2) $\AA$), have been determined by single-crystal X-ray diffraction techniques in the cubic space group Fd3 at $21(1)^{\circ}C.$ The structures were refined to the final error indices, R1 = 0.058 and R2 = 0.065 with 637 reflections for Cd32Cs28-X and R1 = 0.086 and R2 = 0.113 with 521 reflections for Cd28Rb36-X for which I > $3\sigma(I)$. In the structure of Cd,sub>32Cs28-X, 16 Cd2+ ions fill the octahedral sites I at the centers of the double six rings (Cd-O = $2.358(8)\AA$ and O-Cd-O = $90.8(3)^{\circ}$ ). The remaining 16 Cd2+ ions occupy site II (Cd-O = $2.194(8)\AA$ and O-Cd-O = $119.7(4)^{\circ})$ and six Cs+ ions occupy site II opposite to the single six-rings in the supercage; each is $2.322\AA$ from the plane of three oxygens (Cs-O = 3.193(13) and O-Cs-O = $73.0(2)^{\circ}).$ Aboutten Cs+ ions are found at site II', $1.974\AA$ into the sodalite cavity from their three oxygen plane (Cs-O = $2.947(8)\AA$ and O-Cs-O = $80.2(3)^{\circ}).$ The remaining 12 Cs+ ions are distributed over site III' (Cs-O = 3.143(9) and O-Cs-O= $59.1(2)^{\circ})$. In the structure of Cd28Rb36-X, 16 Cd2+ ions fill the octahedral sites I at the center of the double-sixrings (Cd-O = 2.349(15) and O-Cd-O = $91.3(5)^{\circ}$ ). Another 12 Cd2+ ions occupy two different II sites (Cd-O = $2.171(18)/2.269(17)\AA$ and O-Cd-O = $119.7(7)/113.2(7)^{\circ}).$ Fifteen Rb+ ions occupy site II (Rb-O = $2.707(17)\AA$ and O-Rb-O = $87.8(5)^{\circ}).$ The remaining 21 Rb+ ions are distributed over site III' (Rb-O = $3.001(16)\AA$ and O-Rb-O = $60.7(4)^{\circ})$. It appears that the smaller and more highly charged Cd2+ ions prefer sites I and Ⅱ in that order, and the larger Rb+ and Cs+ ions, which are less able to balance the anionic charge of the zeolite framework, occupy sites II and II' with the remainder going to the least suitable site in the structure, site III'.The maximum Cs+ and Rb+ ion exchanges were 30% and 39%, respectively. Because these cations are too largeto enter the small cavities and their charge distributions may be unfavorable, cation-sieve effects might appear.

• Journal of the Korean Chemical Society
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• v.50 no.1
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• pp.14-22
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• 2006

the basic model of chemical reactor using glow discharge, we used cathode discharge cell with vacant cavity in the middle. Currently glow discharge is widely studied as a radiation source or atomization device in atomic spectroscopy and remarkable technological achievements are made through the graft with other analysis devices such as microanalysis and steel analysis.1 Additionally, as the characteristics of basic glow discharge and radiation have been reviewed many times, those results could be used in this experiment.2-3 In 1993, an article regarding the treatment of poisonous gas in the air using low temperature plasma was published. According to this article, if DC Glow Discharge is used under continuous atmospheric flow, poisonous gases such as SO2 and NO can be removed.4 Based on those findings, we designed highly efficient reactor where stable air plasma is composed and all air flow pass the negative glow area passing through the tube. It was observed that the cathode tube type glow discharge developed in this study would be economical, easy to use and could be used as radiation source as well.

• The Journal of the Korean bone and joint tumor society
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• v.13 no.2
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• pp.96-104
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• 2007

Purpose: The authors investigated whether 35 flexible nail-rotating hinge composite reconstructions around knee joint minimize junctional osteolysis of host bone. Material and Method: The reconstructive technique was as follows: 1) en bloc tumor resection, 2) filling of the host bone marrow cavity with multiple Ender nails, 3) assembling the Ender nails and an Endo-Link type total knee component with wire and bone cement. Result: Mean follow-up was 53 months (ranged 30~79). At final follow-up, 29 patients retained a mobile joint. Resection of more than 40% of bone showed a positive relationship with junctional hypertrophy (p=0.028). Eight patients showed nail breakage and eight prostheses were removed due to early or late infection. The cumulative prosthetic survival rate was 33% at 6 year. Average functional score according to the MSTS criteria was 26.8. Conclusion: Mid-term evaluations showed that results were fair. The revision process was straightforward. Junctional hypertrophy observed appears to give some clues as to how to minimize osteolysis at the prosthesis-host junction after modular prosthesis fixation.

• Journal of Oral Medicine and Pain
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• v.31 no.4
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• pp.275-281
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• 2006

The purpose of this study was to investigate whether there were any changes in taste function with buring mouth syndrome(BMS). 133 subjects (31 males and 99 females) were included for the study and they were categorized into 2 groups BMS 33 persons, control 100 persons) and investigated in the Dept. of Oral Medicine, Pusan National University Hospital from April,2005 to February,2006. The electrical taste thresholds were measured using an electrogustometer of 4 different sites in oral cavity (tongue tip, tongue lateral, circumvallate papillar and soft palate). The results were as follows : 1. The electrical taste threshold in BMS group was very significantly low. 2. The electrical taste thresholds in male and female of BMS group were significantly lower each other than those of control group 3. The electrical taste threshold of BMS group according to single/multiple lesions and chronicity were not different. 4. After treatment, electrical taste threshold and NAS decreased more significantly.