• Title/Summary/Keyword: Causal Condition

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Functional Analysis of Genes Specifically Expressed during Aerial Hyphae Collapse as a Potential Signal for Perithecium Formation Induction in Fusarium graminearum

  • Yun-Seon Choi;Da-Woon Kim;Sung-Hwan Yun
    • The Plant Pathology Journal
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    • v.40 no.1
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    • pp.83-97
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    • 2024
  • Fusarium graminearum, the causal agent of Fusarium head blight (FHB) in cereal crops, employs the production of sexual fruiting bodies (perithecia) on plant debris as a strategy for overwintering and dissemination. In an artificial condition (e.g., carrot agar medium), the F. graminearum Z3643 strain was capable of producing perithecia predominantly in the central region of the fungal culture where aerial hyphae naturally collapsed. To unravel the intricate relationship between natural aerial hyphae collapse and sexual development in this fungus, we focused on 699 genes differentially expressed during aerial hyphae collapse, with 26 selected for further analysis. Targeted gene deletion and quantitative real-time PCR analyses elucidated the functions of specific genes during natural aerial hyphae collapse and perithecium formation. Furthermore, comparative gene expression analyses between natural collapse and artificial removal conditions reveal distinct temporal profiles, with the latter inducing a more rapid and pronounced response, particularly in MAT gene expression. Notably, FGSG_09210 and FGSG_09896 play crucial roles in sexual development and aerial hyphae growth, respectively. Taken together, it is plausible that if aerial hyphae collapse occurs on plant debris, it may serve as a physical cue for inducing perithecium formation in crop fields, representing a survival strategy for F. graminearum during winter. Insights into the molecular mechanisms underlying aerial hyphae collapse provides offer potential strategies for disease control against FHB caused by F. graminearum.

The Bacterial Contamination in Glasses for Vision Correction (시력 교정용 안경의 세균 오염)

  • Kim, Heung-Soo;Hwang, Seock-Yeon;Yun, Chi-Young
    • Journal of Korean Ophthalmic Optics Society
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    • v.18 no.1
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    • pp.67-73
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    • 2013
  • Purpose: Recently, bacterial contamination of equipment and accessories required for vision correction has become a main causal factor in ophthalmic diseases. Thus, We investigated on both the actual condition of bacterial contamination from glasses of vision correction. Methods: Investigation of microorganisms was carried out with a group of 145 glasses wearers, composed of 36 elementary school students, 37 middle school students, 38 high school students, 10 college students, and 32 aged men. Results: Seventeen species of bacteria are detected from glasses of vision correction: B. cereus, B. licheniformis, Bacillus sp., CNS, Enterococcus sp., Escherichia coli, Proteus sp., Pseudomonas sp., Serretia sp., Streptococcus sp., Staphylococcus epidermidis, Staphylococcus aureus, Streptococcus hemolyticus,, Acinetobacter sp., Enterobacter cloacae, GNR, and Pseudomonas aeruginosa. Among 17 species of bacteria, there are some potential causative agents for keratitis, corneal ulcer, Acute dacryocystitis, Orbital cellulitis, Periphlebitis retinae, Marginal blepharitis, and Acute conjunctivitis. Enterobacter cloacae, Pseudomonas aeruginosa and Staphylococcus epidermidis cause keratitis. Pseudomonas sp., and Staphylococcus aureus cause corneal ulcer. Staphylococcus aureus causes acute dacryocystitis, orbital cellulitis, periphlebitis retinae, marginal belpharitis. Streptococcus hemolyticus causes acute conjunctivitis. Conclusions: In summation, it is verified that hazardous, opportunistic and infectious microorganisms exist in glasses for vision correction. Ophthalmic diseases are predicted. Therefore, supplementary research on the development of a cleaning solution to cleanse the infection and of an effective method to remove microorganisms is required.

Causality between Entrepreneurial Orientation and Business Performance: Conditional Indirect Effect of New Product Development and Organizational Size (기업가적 지향성과 경영성과 간 관계: 조직규모에 따른 신제품개발의 조건부 간접효과)

  • Choo, Seungyoup;Woo, Hyungrok
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.15 no.3
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    • pp.133-144
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    • 2020
  • This study examines the indirect effects of new product development(NPD) on the relationship between entrepreneurial orientation(EO) and business performance is contingent on organization size. Although previous studies have revealed that EO has a positive effect on business performance and NPD, there have been no research attempts to comprehensively grasp the causal path of EO, NPD, and business performance. Therefore, this study analyzed the causal path focusing not only on final financial business performance affected by EO but also on the mediating role of new product development, which is an intermediate performance. Based on the sample of 3,299 firms from the 2018 Entrepreneurship Survey(Corporate), we analyzed the EO-NPD-business performance relationship and explored whether such an indirect effect of EO on business performance differs depending on the size of the firm. The results showed that EO has a positive impact on business performance and NPD. In addition, NPD positively mediates the relationship between EO and business performance under the condition of large size firm, although NPD does not have a direct effect on business performance. With the findings, the current study has principal implications for practicing managers. The result of this study is not to suggest that NPD triggered by EO is a panacea for improving final business performance. The study suggests a need to equip organizational capabilities to successfully commercialize new products and appeal to the market and customers, beyond simply developing new products seeking newness based on EO.

Notes on Powdery mildew of Ailanthus altissima caused by Phyllactinia corylea (Pers.) Karst (Phyllactinia corylea (Pers.) Karst에 의(依)한 가중나무 흰가루병(病))

  • Kim, Ki Chung
    • Journal of Korean Society of Forest Science
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    • v.4 no.1
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    • pp.9-13
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    • 1965
  • Powdery mildew of Ailanthus altissima Sw. was first reported by J.S. Park in Korea, 1961. According to his report, this disease was found on the leaves of this tree species collected in Jeongup, 1957, and in Taejon, 1958. He described morphological characters of this pathogen and described also that the causal fungus may be closely related with Phyllactinia corylea. This disease which appears dusty grayish yellow molds under surface of leaves was collected again by the author in Kwangju, 1962. The present works were undertaken to make clear the species of causal fungus by means of the morphology and pathogenecity. According to the following results, the pathogen was identified as Phyllactinia corylea (Pers.) Karst. Morphological characters of the fungus Mycelia persistent or more or less evanescent; matured conidia solitary, aseptate, short-clavate to clavate to clavate, hyaline or yellowish, granulate, $44.6-89.2{\times}9.3-24.2{\mu}$, average $64.8-17.8{\mu}$ in size; conidiophores elongate clavate or columnar, hyaline, 2-3 septate, $122.8-346.0{\times}3.7-7.4{\mu}$, average $208.8{\times}6.3{\mu}$; per-thecia usually scattered, rarely gregarious, dark brown to black, depressed globose to globose, $223.2-297.6{\mu}$, average $267.8{\mu}$ in diameter; appendages 12-19, usually 15 in number, hyaline, straight, needle-shaped, sharply pointed at the apex and bulbous at the base, aseptate, $93.0-310.0{\times}5.0-8.0{\mu}$, average $173.3{\times}6.4{\mu}$ in size; asci elongate ellipsoidal to broadly clavate, hyaline, more or less stalked, 8-13 in number, $68.5-76.6{\times}26.1-34.2{\mu}$, average $71.4{\times}29.0{\mu}$ in size; ascospores 2-4, usually 2 in number, hyaline or yellowish, aseptate, ellipsoidal or ovate, $27.7-34.2{\times}14.7-17.9{\mu}$, average $25.5{\times}13.9{\mu}$ in size. Pathogenicity of the fungi In order to make clear the species of the fungus and the pathogenic differences of Phyllactinia fungi which are collected around the contaminated area and seemed to be related to Ailanthus powdery mildew, some inoculation experiments were performed. 1. Cross inoculation to several tree species with their pathogen: Tested materials; Phyllactinia in question on Ailanthus altissima Sw. Ph. fraxini (DC.) Homma. On Alnus firma S. et Z. Ph. moricola (P. Henn.) Homma on morus alba L. According to the results of the experiments, the reactions were all negative with the exception of the original hosts of tested fungi. 2. Inoculation to Picrasma ailanthoides Planch. : The appearance of symptom on the leaves of P. ailanthoides is not distinct, but more or less mycelial growth. Therefore, under the optimal condition in glass chamber, it may be possible to success artificially.

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The Importance of Social Intimacy as a Sufficient Condition for Anthropomorphism and Positive User Experience (의인화와 긍정적인 사용자 경험의 충분조건으로서 사회적 친밀감의 중요성)

  • Lee, Da-Young;Han, Kwang-Hee
    • Science of Emotion and Sensibility
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    • v.25 no.3
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    • pp.15-32
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    • 2022
  • This study seeks to clarify the mechanisms of anthropomorphism and positive user experience. This study adopts the "computers are social actors" (CASA) paradigm to verify the causal relationship between social response and anthropomorphism and correctly explicate this paradigm. The intimacy-forming and anthropomorphizing effects of deep self-disclosure in interpersonal relationships were replicated in relationships between humans and conversational agents to induce both social response and anthropomorphism. Then, the mediating effect of intimacy on the anthropomorphizing effect of deep self-disclosure was explored with psychological models that revealed the causal relationships between social connections, including intimacy and anthropomorphism. Furthermore, we explored how intimacy and anthropomorphism trigger positive user experiences. The results demonstrated that the deeper the self-disclosure depth was, the more intimate and humanly the agent was perceived and the more positive the user experience was. In addition, the effect of self-disclosure depth on anthropomorphism and positive user experience was completely mediated by intimacy. This means that when using a computer with interpersonal characteristics, people anthropomorphize it and have a positive experience because people react socially to objects with social cues. This study bridges the gap between the CASA paradigm and anthropomorphism research, suggesting the possibility of psychological explanations for the principle of human-computer interactions. In addition, it explicates the mechanism of anthropomorphism and positive user experience, emphasizing the importance of social response-that is, intimacy.

The Fatigue Experience of Shift Work Nurses (교대근무간호사의 피로경험)

  • Kho Hyo Jung;Kim Myung Ye;Kwon Young Sook;Kim Chung Nam;Park Kyung Min;Park Jung Sook;Park Young Suk;Park Cheong Ja;Shin Young Hee;Lee Kyung Hee;Lee Byung Sook;Lee Eun Joo
    • Journal of Korean Public Health Nursing
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    • v.18 no.1
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    • pp.103-118
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    • 2004
  • The purpose of this study was to understand the process and investigate basic theory of fatigue experience of shift work nurses. The present study adopted grounded theory methodology on fatigue of shift work nurses. The participants for this study were 15 shift work nurses who were in the age of 25 to 35, the clinical experience of 2 to 14 years and the work department of ICU. ER. ward and delivery room. The data were collected from 2000 to 2003 by using interviews and observations. The contents of the interviews were tape-recorded and were drawn through repeated method. And then were analyzed into the concept, subcategories, and categories with the open coding process and axial coding was done to identify the relationships of the concepts and categories according to the paradigm models. The core category generated, which was a central phenomena of the exhaustion process. The causal condition is change events. The central condition of exhaustion were sorted as physical discomfort, decreasing vigor, psychological instability, feeling of sleeping desire, changing face impression and being heavy body. The intervening condition were discovered as social$\cdot$ psychology$\cdot$physical resist and positive$\cdot$negative interaction strategies. The consequences of the fatigue process is the short term exhaustion relief and long term residual exhaustion. The fatigue process of this study was 'break through exhaustion' of change event-exhaustion-resist-resolve intervention-adaptation. This study offers better understanding on fatigue process of shift work nurses and may facilitate more appropriate interventive strategies to support, information and knowledges according to fatigue process.

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The Use Criteria and Appropriateness of Korean Classification of Diseases(KCD) Focused on Emmeniopathy (월경병을 중심으로 본 한국표준질병사인분류(KCD)의 사용 기준과 적합성)

  • Kang, You-Jeong;Lee, In-Seon;Cho, Hye-Sook;Lee, Seung-Hwan;Bae, Geung-Mee
    • The Journal of Korean Obstetrics and Gynecology
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    • v.24 no.4
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    • pp.126-149
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    • 2011
  • Purpose: KCDO-3(Korean Classification of Diseases(Oriental Medicine)-third edition) being used in January, 2010 accepted the KCD(Korean Classification of Diseases) and added disease pattern and syndrome of oriental medicine. But, the diagnoses of oriental medicine are too uncertain to express in A00-Z99(KCD). In this case, you should choose in U codes under the KCD use guidelines, but U codes are not capable of representing the symptoms too. So, we suggest the use criteria and consider the weakness of the U codes with medical records of patients who visited with amenorrhea or oligomenorrhea. Methods: We referred medical records of patients who visited oriental obstetrics and gynecology from January 1st to December 31st, 2010. From among them, we set up 122 patients who related with emmeniopathy as target group and searched codes distribution based on medical records. And we described that the process of choosing appropriate codes based on the medical records of 49 amenorrhea or oligomenorrhea patients. Results and Conclusions: The emmeniopathy is divided into menstrual disorder, amenorrhea and systemic disorders at the period of menstruation. And emmeniopathy is expressed in some codes such as N91, N92, N93, N94, U321, U77. When a patient visit hospital, a doctor should choose causal codes when there is confirmed diagnosis. Otherwise, a doctor chooses symptom codes. And if there are more than two diagnosis consistent with definition of chief condition, a doctor should code the first listed diagnosis as a chief condition. Because KCD-5 is classified according to western medical diagnosis, it is difficult to choose in KCD-5 when we diagnosed with disease pattern and syndrome of oriental medicine. But U codes are also deficient to express various condition of emmeniopathy. So we should add 'deficiency and detriment of the thoroughfare and conception vessels', 'prolonged menstruation' and various systemic disorders at the period of menstruation.

A study on communication process with team members perceived by team leader in corporation (기업 팀장이 인식하는 팀원과의 의사소통 과정 연구)

  • Baek, Eun Jung;Shin, Hyo Jung
    • The Korean Journal of Coaching Psychology
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    • v.5 no.2
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    • pp.25-51
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    • 2021
  • The purpose of this study is to deeply explore the communication process with team members perceived by team leader. To this end, in-depth interviews were conducted with 10 team leaders, and analyzed according to the grounded theory research method procedure suggested by Strauss and Corbin. As a results, a total of 51 concepts, 17 subcategories, and 8 categories were derived. As a causal condition, the concept of 'contemplating and reinterpreting communication necessary for the organization' was derived, and the central phenomenon was 'intentional effort made in parallel with work and private conversations'. The contextual condition was 'recognizing the need to cope with environmental changes', and the mediating condition was 'self-reflection and self-coaching time' was derived. The action/interaction strategy was conceptualized as a communication process with task-oriented coping, conflict resolution coping, and relationship promotion coping, and was confirmed as 'recognizing virtuous cycle communication within the organization' as a result of interaction with the central phenomenon. As a result of analysis of the team leader's communication process, the effort stage, approach stage, coping stage, and cycle stage were shown. As a result of the type analysis, task-oriented coping was a facilitator, conflict resolution coping was a supporter, and relationship promotion coping was a considerate. This study is an empirical study on how the corporate team leader perceives and expresses communication in the relationship with the team members.

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Review of 2011 Major Medical Decisions (2011년 주요 의료 판결 분석)

  • Yoo, Hyun-Jung;Seo, Young-Hyun;Lee, Jung-Sun;Lee, Dong-Pil
    • The Korean Society of Law and Medicine
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    • v.13 no.1
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    • pp.199-247
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    • 2012
  • According to the review and analysis of medical cases that are assigned to the Supreme Court and all local High Court in 2011 and that are presented in the media, it was found that the following categories were taken seriously, medical and pharmaceutical product liability, the third principle of trust between medical institutions, negligence and causation estimation, responsibility limit, the meaning of medical records and related judgment of disturbed substantiation, Oriental doctors' duties to explain the procedures, IMS events, whether one can claim for each medical care operated by non-physician health care institutions to the nonmedical domain in the National Health Insurance Corporation, and the basis of norms for each claim. In the cases related to medical pharmaceutical product liability, Supreme Court alleviated burden of proof for accidents with medical and pharmaceutical products prior to the practice of Product Liability Law and onset the point of negative prescription as the time of damage strikes to condition feasibility of the specific situation. In the cases related to the 3rd principle of trust between medical institutions, the Supreme Court refused to sentence the doctor who has trusted the judgment of the same third-party doctors the violations of the care duty. With respect to proof of a causal relationship and damages in a medical negligence case, the Supreme Court decided that it is unjust to deny negligence by the materials of causal relationship rejecting the original verdict and clarified that the causal relationship shall not deny the reasons to limit doctors' responsibilities. In order not put burden on patients with disadvantages in which medical records and the description of the practice or the most fundamental and important evidence to prove negligence and causation are being neglected, the Supreme Court admitted in the hospital's responsibility for the case of the neonate death of suffocation without properly listed fetal heart rate and uterine contraction monitor. On the other hand, the Seoul Western District Court has admitted alimony for altering and forging medical records. With respect to doctors' obligations to description, the Supreme Court decided that it is necessary to explain the foreseen risks by the combination of oriental and western medicines emphasizing the right of patient's self-determination. However, questions have arisen whether it is realistically feasible or not. In a case of an unlicensed doctor performing intramuscular stimulation treatment (IMS), the Supreme Court put off its decision if it was an unlicensed medical practice as to put limitation of eastern and western medical practices, but it declared that IMS practice was an acupuncture treatment therefore the plaintiff's conduct being an illegal act. In the future, clear judgment on this matter should be made. With respect to the claim of bills from non-physical health care institutions, the Supreme Court decided to void it for the implementation of the arrangement is contrary to the commitments made in the medical law and therefore, it is invalid to claim. In addition, contrast to the private healthcare professionals, who are subject to redemption according to the National Healthcare Insurance Law, the Seoul High Court explicitly confirmed that the non-professionals who receive the tort operating profit must return the unjust enrichment and have the liability for damages. As mentioned above, a relatively wide range of topics were discussed in medical field of 2011. In Korea's health care environment undergoing complex changes day by day, it is expected to see more diverse and in-depth discussions striding out to the development in the field of health care.

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Distribution of Hypertension According to Working Conditions among Korean Worker (근로환경에 따른 우리나라 근로자의 고혈압 분포)

  • Kim, Young Sun;Rhee, Kyung Yong;Song, Se Wook
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.24 no.4
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    • pp.556-565
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    • 2014
  • Objectives: This study is aimed at inquiring into the grasp of real condition of working environment and improvements by calculating the hypertension distribution consequent on job stress risk and exposure level of alleviating factors. In addition, this study is intending to estimate the hypertension distribution through socio-demographic factors and level of stressors occurring at working environment, such as high workload, low control, low support, job insecurity, long working hours, low income. Methods: This study estimated the hypertension distribution using the tertiary Korean Working Conditions Survey data, and conducted comparative analysis according to the category of individual questionnaire items using odds ratio. Result: As a result of study, it was found that in the event that working environment satisfaction is low and business & an immediate superior's attitudes are negative, the hypertension distribution was high. Particularly, it was found that physical risk factor musculoskeletal risk factor, and mental risk factor in a workplace were all increasing the hypertension distribution. Conclusions: With the aged workers' labor market participation ratio increasing, hypertension could be a major issue in the field of Occupational Safety and Health. Thus, it's necessary that the relevant employer should lower the hypertension distribution through creation of pleasant working environment and inducement of workers to improve in the relations with their superiors. As for the uppermost limit of this study, there is a limit to clarifying the mechanism of hypertension through multivariate statistics analysis because it's difficult to establish causal relationship by individual questionnaire item as the working conditions survey is made by cross-sectional study. In the follow-up research, this study is going to do research on the mechanism of hypertension through questionnaire supplementation and in-depth analysis.