• 제목/요약/키워드: Case-deletion

검색결과 167건 처리시간 0.023초

IP 주소 검색을 위한 가중 이진 프리픽스 트리 (Weighted Binary Prefix Tree for IP Address Lookup)

  • 임창훈;임혜숙;이보미
    • 한국통신학회논문지
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    • 제29권11B
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    • pp.911-919
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    • 2004
  • IP 주소 검색은 인터넷 라우터의 필수적인 기능의 하나로서, 라우터 전체의 성능을 결정하는 중요한 요소이다. 소프트웨어에 기반한 IP 주소 검색 방식의 성능 평가 기준 중 가장 중요한 것은 라우터의 처리 속도를 보장해 주는 의미를 갖는 최대 메모리 접근 횟수이다. 이진 프리픽스 트리 방식(BPT)은 최대 메모리 접근 횟수에 있어서 기존의 다른 소프트웨어에 기반한 방식 중 우수한 방식이지만, 트리의 구조가 불균형적이 되는 단점이 있다. 본 논문에서는 기존의 BPT 방식의 트리 생성 과정에 가중치 개념을 추가하여, 완전 균형 트리에 매우 근접하는 트리를 생성하는 가중 이진 프리픽스 트리 (WBPT) 방식을 제안한다. 제안하는 WBPT 방식은 기존의 소프트웨어에 근거한 방식들에 비교하여 최대 메모리 접근 횟수에 있어서 가장 적은 성능을 보인다. 또한 3만 개 정도의 프리픽스에 대해서 L2 캐쉬에 저장이 가능한 정도의 작은 메모리 크기를 요구하구 프리픽스의 추가, 삭제가 용이하므로 실제적인 라우터의 IP 검색을 위하여 사용될 수 있는 방식이다.

The first Korean case of 2p15p16.1 microdeletion syndrome, characterized by facial dysmorphism, developmental delay, and congenital hypothyroidism

  • Jin Young Cho;Tae Kwan Lee;Yoo Mi Kim;Han Hyuk Lim
    • Journal of Genetic Medicine
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    • 제19권2호
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    • pp.105-110
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    • 2022
  • The microdeletion syndrome of chromosome 2p15p16.1 (MIM: 612513) is an extremely rare contiguous gene deletion syndrome. Microdeletions of varying sizes in the 2p15-16.1 region are associated with developmental delay, intellectual disability, autism spectrum disorder, hypotonia, and craniofacial dysmorphism. Previous studies have identified two critical regions: the proximal 2p15 and distal 2p16.1 regions. BCL11A, PAPOLG, and REL genes play crucial roles in patients with 2p16.1 microdeletion. To our knowledge, only 39 patients have been reported as having 2p15p16.1 microdeletion syndrome. Here, we present another patient with 2p15p16.1 microdeletion syndrome. A nine-month-old boy was referred to our clinic for the psychomotor delay, facial dysmorphism, and congenital hypothyroidism. During his follow-up visits, he was diagnosed with global developmental delay, intellectual disability, abnormal behavior, hypotonia, microcephaly, and abnormal electroencephalography. Using a chromosomal microarray for genetic analysis, a novel, de novo, 622 kb microdeletion of 2p16.1 was identified as one of the critical regions of the 2p15p16.1 microdeletion syndrome. This is the first case of its kind in Korea. We have discussed our case and literature reviews to clarify the relationship between the genes involved and clinical phenotypes in 2p15p16.1 microdeletion syndrome.

변경을 가한 승낙에 관한 CIETAC 사례 연구 - CISG를 중심으로 - (A Study on CIETAC Case about Acceptance with Different Terms - Focus on CISG -)

  • 강호경
    • 한국중재학회지:중재연구
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    • 제24권4호
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    • pp.127-145
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    • 2014
  • The wording of Article 18 shows that a statement made by or other conduct of the offeree indicating assent to an offer is an acceptance. Meanwhile, Article 19 states that this reply with different terms is a rejection of the offer and constitutes a counteroffer. For example, additional or different terms relating, among other things, to the price, payment, quality and quantity of the goods, place and time of delivery, extent of one party's liability to the other, or the settlement of disputes are considered to alter the terms of the offer materially. However, this reply with different terms which do not materially alter the terms of the offer constitutes an acceptance unless the offer or, without undue delay, objects orally to the discrepancy or dispatches a notice to that effect. As a result, the acceptance depends on whether different terms are material or not. CIETEC holds that the deletion of contract violation liability clause is not equal to an alteration to the extent of one party's liability to the other as stipulated in Article 19(3) of the CISG. In addition, CIETAC recognizes that one party had orally accepted the modifications made to the sales confirmation, with even China declaring against an oral contract. Lastly, CIETAC holds that the sales confirmation has been established when both parties signed on the sales confirmation instead of the acceptance being effective. Korean companies should, thus, note these issues when they solve disputes at CIETAC.

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어혈 진단 설문지 개정 연구 (Revision of the modified Blood Stasis Questionnaire II)

  • 장수빈;강병갑;고미미;김평화;정지연
    • 대한예방한의학회지
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    • 제24권2호
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    • pp.95-102
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    • 2020
  • Objectives : The objective of this study was to revise the modified Blood Stasis Questionnaire II. Methods : This revision focused on refining the Korean literature expression of Blood Stasis Questionnaire II consisting of 30-question questionnaire. Seven external experts and five researchers of Korean Institute of Oriental Medicine reviewed the questionnaire and its protocol, while the addition or deletion of questions and changes in scoring method were not dealt with in this revision. Results : Among thirty questions, four questions were corrected to appropriate expressions. In case of eight questions, explanations in Korean or Chinese were added. Thirteen questions in the phrase were changed in sentence form to unify the whole questionnaire. Conclusions : This study introduces the revised version of the modified Blood Stasis Questionnaire II. It is expected that clinical demand of this questionnaire will increase and it will be used vigorously in blood stasis research.

출발시간제약이 존재하는 동적 복합교통망의 K최소시간경로탐색 (A K Least Time Paths Searching Algorithm for Time Dependent Intermodal Transportation Networks with Departure Time Schedule Constraints)

  • 조종석;신성일;문병섭;임강원
    • 대한교통학회지
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    • 제24권3호
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    • pp.167-176
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    • 2006
  • 출발시간제약이 존재하는 통합교통망의 최소시간경로탐색은 도착수단의 도착시간 수단간 환승시간, 대기시간 뿐만 아니라. 다음수단의 출발시간을 고려하는 것이 필요하다. 다수의 교통수단이 존재하는 통합교통망에서는 출발시간제약이 포함되는 경우가 매우 일반적인 현상이다. 이는 철도나 항공 등과 같은 대중교통노선들은 일정한 시간에 서비스를 제공하는 노선별 스케줄을 가지고 있기 때문이다. 본 연구에서는 이러한 출발시간제약조건이 존재하는 통합교통망을 통행시간이 시간대에 따라 동적으로 변화하는 상황에서 K개의 경로를 탐색하는 알고리즘을 개발하고자 한다. 그리고, 이러한 알고리즘개발을 위하여 유입링크기반의 전체경로삭제방식을 확대 적용하는 방안을 제안하며, 사례연구를 통하여 알고리즘의 활용성을 검토한다.

유전자분석으로 진단한 얼굴어깨위팔근육디스트로피 1예 (A Case of Facioscapulohumeral Muscular Dystrophy Confirmed by Genetic Analysis)

  • 이석호;기창석;이승철;박진석;고성호;이규용
    • Annals of Clinical Neurophysiology
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    • 제10권1호
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    • pp.66-69
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    • 2008
  • Facioscapulohumeral muscular dystrophy (FSHD), the third most common inherited muscular dystrophy, is an autosomal dominant disease characterized by progressive weakness and wasting of the facial, shoulder-girdle, upper arm, foot extensor, and pelvic girdle muscles. FSHD is caused by contraction of the polymorphic D4Z4 repeat in the subtelomere of chromosome 4q. However, there has been no report of genetically confirmed FSHD in Korea. We report a patient with FSHD who was found to have a deletion of D4Z4 repeat on chromosome 4q35.

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Factor-analysis based questionnaire categorization method for reliability improvement of evaluation of working conditions in construction enterprises

  • Lin, Jeng-Wen;Shen, Pu Fun
    • Structural Engineering and Mechanics
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    • 제51권6호
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    • pp.973-988
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    • 2014
  • This paper presents a factor-analysis based questionnaire categorization method to improve the reliability of the evaluation of working conditions without influencing the completeness of the questionnaire both in Taiwanese and Chinese construction enterprises for structural engineering applications. The proposed approach springs from the AI application and expert systems in structural engineering. Questions with a similar response pattern are grouped into or categorized as one factor. Questions that form a single factor usually have higher reliability than the entire questionnaire, especially in the case when the questionnaire is complex and inconsistent. By classifying questions based on the meanings of the words used in them and the responded scores, reliability could be increased. The principle for classification was that 90% of the questions in the same classified group must satisfy the proposed classification rule and consequently the lowest one was 92%. The results show that the question classification method could improve the reliability of the questionnaires for at least 0.7. Compared to the question deletion method using SPSS, 75% of the questions left were verified the same as the results obtained by applying the classification method.

Lack of any Association between Insertion/Deletion (I/D) Polymorphisms in the Angiotensin-converting Enzyme Gene and Digestive System Cancer Risk: a Meta-analysis

  • Liu, Jin-Fei;Xie, Hao-Jun;Cheng, Tian-Ming
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권12호
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    • pp.7271-7275
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    • 2013
  • Objective: To investigate the association between the gene polymorphisms of angiotensin-converting enzyme (ACE) and digestive system cancer risk. Method: A search was performed in Pubmed, Medline, ISI Web of Science and Chinese Biomedical (CBM) databases, covering all studies until Sep 1st, 2013. Statistical analysis was performed by using Revman5.2 and STATA 12.0. Results: A total of 15 case-control studies comprising 2,390 digestive system cancer patients and 9,706 controls were identified. No significant association was found between the I/D polymorphism and digestive cancer risk (OR=0.93, 95%CI = (0.75, 1.16), P=0.53 for DD+DI vs. II). In the subgroup analysis by ethnicity and cancer type, no significant associations were found for the comparison of DD+DI vs. II. Results from other comparative genetic models also indicated a lack of associations between this polymorphism and digestive system cancer risks. Conclusions: This meta-analysis suggested that the ACE D/I polymorphism might not contribute to the risk of digestive system cancer.

A rare case of Sjogren-Larsson syndrome with recurrent pneumonia and asthma

  • Tavasoli, Azita;Sayyahfar, Shirin;Behnam, Babak
    • Clinical and Experimental Pediatrics
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    • 제59권6호
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    • pp.276-279
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    • 2016
  • Sjogren-Larsson syndrome (SLS) is a rare autosomal recessive neurocutaneous disorder with worldwide incidence of 0.4 per 100,000 people. It is characterized by the triad of congenital ichthyosis, spastic diplegia or quadriplegia, and mental retardation. Herein we report a 2-year-old male child with SLS, asthma, and recurrent pneumonia. SLS was confirmed by a molecular genetics study that revealed a deletion mutation in the ALDH3A2 gene. An ALDH3A2 gene mutation results in dysfunction of the microsomal enzyme fatty aldehyde dehydrogenase and impaired metabolism and accumulation of leukotriene B4, which is a key molecule and a pro-inflammatory mediator in developing allergic diseases, especially asthma. An increased level of leukotriene B4 has been reported in SLS patients. As far as we are aware, this is the first report of SLS associated with asthma and recurrent pneumonia. In conclusion, pediatricians should be aware of and evaluate patients with SLS for possible associated asthma and allergic disorders.

A DiGeorge Syndrome with both Basal Ganglia Calcification with 22q11.2 Deletion

  • Kim, Young Han;Choi, Joong Wan;Ryu, Hye Won;Bae, Eun Ju;Oh, Phil Soo;Lee, Hong Jin
    • 대한유전성대사질환학회지
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    • 제14권2호
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    • pp.163-167
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    • 2014
  • DiGeorge syndrome is a disorder caused by microdeletion in chromosome 22q11.2 with various abnormalities including cardiac anomaly, facial dysmorphism, thymic and parathyroid hypoplasia, cleft palate and immune dysfunction. The frequency of hypocalcemia caused by hypoparathyroidism is known to be approximately 60% of DiGeorge syndrome. It is known that the disorder mostly occurs in the neonatal period and the symptoms are improved afterwards. Herein we report a case of DiGeorge syndrome only accompanied by hypocalcemia caused by hypoparathyroidism without other abnormalities. She was first diagnosed only at the age of 22 with basal ganglia calcification that had been discovered in brain CT (Computed tomography).