• Title/Summary/Keyword: Carrying capacity model

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The Within-Host Population Dynamics of Normal Flora in the Presence of an Invading Pathogen and Antibiotic Treatments

  • Kim, Jung-Mo;Lee, Dong-Hwan;Song, Yoon-Seok;Kang, Seong-Woo;Kim, Seung-Wook
    • Journal of Microbiology and Biotechnology
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    • v.17 no.1
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    • pp.146-153
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    • 2007
  • A mathematical competition model between normal flora and an invading pathogen was devised to allow analysis of bacterial infections in a host. The normal flora includes the various microorganisms that live on or within the host and act as a primary human immune system. Despite the important role of the normal flora, no mathematical study has been undertaken on models of the interaction between it and invading pathogens against a background of antibiotic treatment. To quantify key elements of bacterial behavior in a host, pairs of nonlinear differential equations were used to describe three categories of human health conditions, namely, healthy, latent infection, and active infection. In addition, a cutoff value was proposed to represent the minimum population level required for survival. The recovery of normal flora after antibiotic treatment was also included in the simulation because of its relation to human health recovery. The significance of each simulation parameter for the bacterial growth model was investigated. The devised simulation showed that bacterial proliferation rate, carrying capacity, initial population levels, and competition intensity have a significant effect on bacterial behavior. Consequently, a model was established to describe competition between normal flora and an infiltrating pathogen. Unlike other population models, the recovery process described by the devised model can describe the human health recovery mechanism.

Distribution of shear force in perforated shear connectors

  • Wei, Xing;Shariati, M.;Zandi, Y.;Pei, Shiling;Jin, Zhibin;Gharachurlu, S.;Abdullahi, M.M.;Tahir, M.M.;Khorami, M.
    • Steel and Composite Structures
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    • v.27 no.3
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    • pp.389-399
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    • 2018
  • A perforated shear connector group is commonly used to transfer shear in steel-concrete composite structures when the traditional shear stud connection is not strong enough. The multi-hole perforated shear connector demonstrates a more complicated behavior than the single connector. The internal force distribution in a specific multi-hole perforated shear connector group has not been thoroughly studied. This study focuses on the load-carrying capacity and shear force distribution of multi-hole perforated shear connectors in steel-concrete composite structures. ANSYS is used to develop a three-dimensional finite element model to simulate the behavior of multi-hole perforated connectors. Material and geometric nonlinearities are considered in the model to identify the failure modes, ultimate strength, and load-slip behavior of the connection. A three-layer model is introduced and a closed-form solution for the shear force distribution is developed to facilitate design calculations. The shear force distribution curve of the multi-hole shear connector is catenary, and the efficiency coefficient must be considered in different limit states.

A development of creative capstone design process by product and mold design (제품 및 금형 연계 창의 캡스톤 디자인 교육과정에 관한 연구)

  • Kim, Kyung-A;Han, Seong-Ryeol
    • Design & Manufacturing
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    • v.13 no.4
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    • pp.45-50
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    • 2019
  • The fourth industrial revolution calls for an integrated talent by improving working-level skills within the big framework of creativity and convergence. Therefore, university education focuses on solving the problem of practical ability education by improving employment ability. Based on this improvement in practical skills, this study is based on the field-based design curriculum of Capstone. Currently, the Capstone Design Course is being implemented at most universities, extending its scope to the fields of engineering, humanities, social studies and arts. However, there is a limit to the core concept of Capstone design education and capacity education developed in line with the foreign educational environment and applied directly to our nation's university education. In terms of overseas cases, the core focus is to develop practical, design, and prototype capabilities by forming a team among all grades and multidisciplinary institutions to support the capital and manpower of the industry. However, the nation's industrial linkage and curriculum have difficulties in carrying out multi-disciplinary education. In this study, students were asked to team up and solve the challenges that the industry needs based on the expertise acquired in the lower grade curriculum by applying majors and 3D printing through the first and second semester courses of the fourth grade to address these limitations. In addition, business skills for the process of creativity and leadership experience in our country through a suitable design capstone class to review the efficiency of education by applying a model. In order to achieve the purpose of Capstone design subject, the goal setting, class model composition, class model application, verification and evaluation, and final class model development procedures were carried out. Through this process, it will be used as a basic material for educating design class capstone design.

Development of Impact Factor Response Spectrum based on Frequency Response of Both Ends-Fixed Beam for Application to Continuous Bridges (연속교 적용을 위한 양단고정지지 보의 진동수 기반 충격계수 응답스펙트럼 개발)

  • Roh, Hwasung;Lee, Huseok;Park, Kyung-Hoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.12
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    • pp.301-306
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    • 2016
  • In bridge performance assessments, a new load carrying capacity evaluation model of simple bridges was proposed, which is based on the developed simple support impact factor spectrum. In this paper, a conservative assumption that the inner span with the both ends fixed boundary condition is ideal for applying the impact factor response spectrum for continuous bridges. The impact factor response spectrum has been proposed based on this assumption. The response spectrum by comparing the numerical analysis result and actual measurement data verified the applicability. The analysis was loading the moving load of DB-24 in a six-span continuous bridge, which was the same as the actual measurement data, the dynamic response was measured in the fourth span. The frequency of the bridge was obtained by FFT on the acceleration response and the span-frequency of sample bridge was calculated by the frequency. The impact factor of the sample bridge was determined by applying the span-frequency of the bridge to the proposed response spectrum; it was similar to the result of comparing the actual measured impact factor. Therefore, the method using the impact factor response spectrum based on the frequency response of both ends-fixed beam was found to be applicable to an actual continuous bridge.

Optimum Population Projection in Korea: An Environmental Perspective (환경 측면에서 한국의 적정인구 추계)

  • Jeong, Dae-Yuon
    • Korea journal of population studies
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    • v.29 no.1
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    • pp.269-292
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    • 2006
  • The current environmental problem is global, and threatens the very existence of human beings. Many factors have been argued as the causes of environmental problem. The examples include anthroponcentric human perspective on nature, increase in the knowledge on nature, development of technology, economic growth and unequal distribution, and population increase, etc. The scholars who argues population increase have focused on over-population. However, the estimation of optimum population size has not been attempted in terms of environmental carrying capacity. In such a context, this paper aims at estimating optimum population size in South Korea in terms of environmental carrying capacity. The estimation was done from two approaches. One was based on the state of environment, the other was based on 'the desirable state of environment' Koreans expect. The former is termed an objective approach, while the latter is termed an approach based on social consensus. About 47.5 millions were estimated from the former approach, and 48.5 millions from the latter approach. However, optimum population size increase by 50.5 millions if government increase environmental budget to 2.00% among total budget. As such, different optimum population size is estimated according to the values of variables. The most significant variable determining optimum population size is environmental budget, and followed by supply of clean energy. The estimated optimum population size was based on the time-series data from 1993 to 2002. Therefore, time-series data collected from other years will result in different estimation model, and then different optimum population size will be estimated.

Simple Model for Preliminary Design of Hexagrid Tall Building Structure (헥사그리드 고층건물구조의 예비설계를 위한 단순모델)

  • Lee, Han-Ul;Kim, Young-Chan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.6
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    • pp.13-20
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    • 2017
  • High-rise building shapes are changing from orthogonal to irregular form and the current trend is to arrange members in geometric grid-patterns at the perimeter of buildings. This study proposes a simple model for the preliminary design of a hexagrid high-rise building. The size of the cross section is set to be different at each module and hexagrid unit, which is different from the previous studies in which all hexagrid members were the same. To examine the effect of hexagrid size on structural performance, 60-story hexagrid buildings with 1-, 2- and 4-story high modules are designed and analyzed. Maximum lateral displacement, steel tonnage, load carrying percentage of perimeter frame and combined strength ratio are compared for 15 buildings. As the lateral load carrying capacity of hexagrid structure was inferior to a diagrid structural system, proper lateral stiffness should be allocated to the core frame in a hexagrid structure. The best ratio of flexural to shear deformation was 4 and larger unit size was better in considering constructional cost and structural efficiency. As the maximum lateral displacements of the buildings were within 84%~108% of the limit, the proposed method seems to be applicable to preliminary design of hexagrid buildings.

Numerical and experimental investigation of control performance of active mass damper system to high-rise building in use

  • Park, S.J.;Lee, J.;Jung, H.J.;Jang, D.D.;Kim, S.D.
    • Wind and Structures
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    • v.12 no.4
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    • pp.313-332
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    • 2009
  • This paper numerically and experimentally investigates the control performance of the active mass damper (AMD) systems in a 26-story high-rise building in use. This is the first full-scale application of the AMD system for suppressing the wind-induced vibration of a building structure in Korea. In addition, the AMD system was installed on top of the building already in use, which may be the world's first implementation case. In order to simultaneously mitigate the transverse-torsional coupled vibration of the building, two AMD systems were applied. Moreover, the H-infinity control algorithm has been developed to utilize the maximum capacity of the AMD system. From the results of numerical simulation using the wind load obtained from the wind tunnel tests, it was found that the maximum acceleration responses of the building were reduced significantly. Moreover, the control performance of the installed AMD system was examined by carrying out the free and forced vibration tests. The acceleration responses on top of the building in the controlled case measured under strong wind loads were compared with those in the uncontrolled case numerically simulated by using the wind load deduced from the measured data and a structural model of the building. It is demonstrated that the AMD system shows good control performance in reducing the building accelerations.

A Study on the Flow Characteristics around Intakes within a Sump by PIV (PIV에 의한 흡입수조내 흡입관 주위의 유동특성에 관한 연구)

  • Choi, J. W.;Kim, J. H.;Kim, K. Y.;Kim, Y. T.;Lee, Y. H.
    • The KSFM Journal of Fluid Machinery
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    • v.5 no.3 s.16
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    • pp.33-39
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    • 2002
  • The head-capacity corves for pumps developed by the pump manufacturer are based on tests of a single pump operating in a semi-infinite pool with no nearby walls or floors and with no stray currents. Hence, flow into the pump suction is symmetrical with no vortices or swirling. Pump station designers rely on these curves to define the operating conditions for the pump selected. However, various constraints such as size, cost, and limitations on storage time require walls, floors, and pump intakes to be close proximity to each other. From this background, the authors are carrying out a systematic study on the flow characteristics of intakes within a sump found in pump stations. Model pump intake basin is designed and PIV is adopted as a measuring tool to capture the instantaneous flow patterns. Special attention is paid to investigate the flow patterns near the free surface, side-wall, and back-wall due to different clearances from back-wall to vortical intake pipe. Moreover, the locations and patterns of the various types of vortices that were found in the examinations are discussed.

A study on the Flow Characteristics of a Vortex originated in the Free Surface within a Sump in a Pump Station by PIV (PIV에 의한 펌프장 흡입수조의 자유표면에서 발생하는 와의 운동특성에 관한 연구)

  • Choi, J. W.;Kim, B. S.;Lee, H.;Kim, Y. T.;Lee, Y. H.
    • 유체기계공업학회:학술대회논문집
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    • 2002.12a
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    • pp.95-101
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    • 2002
  • The head-capacity curves for pumps developed by the pump manufacturer are based on tests of a sin91e pump operating in a semi-infinite pool with no nearby walls or floors and no stray currents. Hence, flow into the pump suction is symmetrical with no vortices or swirling. Pump station designers rely on these curves to define the operating conditions for the pump selected. But various constraints such as size, cost, and limitations on storage time require walls, floors, and pump intakes to be close proximity to each other. From this background, the authors are carrying out a systematic study on the flow characteristics of intakes within a sump found within a sump of pump stations. Model pump intake basin is designed and PIV is adopted as a measuring tool to capture the instantaneous flow patterns. Special attention is paid to investigate the flow patterns near the free surface due to different clearances from back-wall to vertical intake pipe with bell mouse and without. Moreover, the locations and vorticities of the various types of vortices that were found in the examinations are discussed.

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Development of the Transfer Case for Power Distribution (동력분배용 중간변속기 개발에 관한 연구)

  • Sim, Ki-Joong;Moon, Hong-Ju;Lee, Youngchoon
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.17 no.2
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    • pp.95-102
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    • 2018
  • This paper presents the development of the transfer case for a 3.5-ton commercial vehicle. A transfer case is composed of many parts, including helical gear, shaft, bearing, planetary gear, and others. Helical gears are currently used as power transmitting gears due to their relatively smooth and silent operation, large load carrying capacity, and operation at higher speeds. The key parameter in transfer case development is the bending stress at the root of a tooth in the helical gear. The bending stress of the helical gear has been studied through theoretical calculation and finite element method (FEM) analysis. Major factors of the bending stress calculation are determined according to American Gear Manufacturers Association (AGMA) standards, and FEM model analysis of the helical gear is conducted. FEM results are compared with theoretical calculations and the difference of the bending stress is described.