• 한국임상수의학회지
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• 제29권5호
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• pp.384-390
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• 2012

본 연구는 심초음파를 이용한 심박출량 측정의 정확성을 평가하고, 수의학에서 심박출량 측정을 위해 처음 적용되는 Automated Contour Tracking method (ACT method)와 다른 심초음파 측정 방법간의 비교를 위한 목적으로 실시되었다. 따라서 본 연구에서는 흡입마취된 비글견에서 심초음파를 이용한 세가지 심박출량 측정 방법 (modified Simpson's method, left ventricular outflow method 그리고 ACT method)과 절대적 표준법으로 사용되어 오고 있는 열희석법의 성적을 비교 분석하였다. 결과의 검정은 피어슨 상관계수와 선형 회귀 분석법을 사용하였다. 실험에 사용된 실험견은 심혈관계 및 전신상태에 이상이 없는 10마리 비글견이며 호흡마취 유도하에 평가가 실시되었다. 실험은 심초음파법으로 측정한 다음 연이어 열희석법으로 측정하는 순서로 진행되었다. 세 가지 심초음파 측정법들은 모두 열 희석법과 유의적인 상관관계(p < 0.05)에 있음을 알 수 있었고 특히, 세 가지 방법 중에서는 ACT method에서 상관관계가 가장 높음을 확인할 수 있었다. 본 실험에서 심초음파를 이용한 심박출량 측정법은 절대적인 심박출량을 제시하지 못하였다. 하지만 심박출량 측정의 절대적 표준법으로 사용되는 열희석법과 유의적인 상관관계가 있음이 확인 되었으므로 심박출량의 간접적인 정보로 활용함으로써 환자의 마취시에 발생할 수 있는 혈역학적 장애의 발견이나 교정을 위해서 유용하게 사용될 수 있음을 확인하였다.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1992년도 추계학술대회
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• pp.130-135
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• 1992

In this paper a new cardiac output control method without pressure sensors is presented for the rotor-driven totally implantable TAH using motor-current wavelet analysis. Theoretical analysis and mock circulation system experiment results show that cardiac output of TAH, which is indeperdent of afterload and sensitively dependent to preload, is well controlled for the independently variable preload.

• 대한의용생체공학회:의공학회지
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• 제12권3호
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• pp.203-208
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• 1991

Balancing left/right cardiac output is essential for the automatic control of total artificial hearts(TAH). A fuzzy logic-based control method is presented. We use left atrial pressure( LAP) ann right a'rial pressure( RAP ) as indicators for left/right balancing. The fuzzy controller has four input variables which are measured LAP and RAP and their gradients. Desired variations in left cardiac output(LCO) and right cardiac output(RCO) are cal- culated to keep LAP and RAP within the Physiological limlts. Computer simulations were performed to adjust fuzzy membership functions for variables and verify this control method. Results from simulations showed that LAP and RAP returned to the physiological limits while AoP and PAP stayed within the physiological limits.

• Journal of Chest Surgery
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• 제19권1호
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• pp.122-133
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• 1986

Thirteen patients with cyanotic cardiac malformations having more complex intracardiac defects, hemodynamics and operative procedures than ones in Tetralogy of Fallot undertaken total surgical corrections from July 1981 to August 1985. The cases of corrective surgery for complex cardiac malformations were 3.9% of all congenital cardiac malformations and 12.6% of cyanotic cardiac malformations. Six patients died within 30 days after surgery. So operative mortality was 46%; Transposition of the great arteries, two of 4 patients, due to low cardiac output syndrome and tracheal bleeding ; Univentricular heart, one of 3 patients, due to bleeding; Corrected transposition of the great arteries, one of 2 patients, due to acute heart failure; Tricuspid atresia, one of 2 patients, due to low cardiac output syndrome; Double outlet right ventricle, one of single patient, due to respiratory failure. The cases of surgical correction for complex cardiac malformations are progressively increasing in numbers. The more accurate evaluation of anatomical condition and hemodynamics in preoperative diagnosis, studies on applicable surgical procedure and perioperative care of patients are necessary in the improvement of clinical and surgical results.

• 전기학회논문지
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• 제60권9호
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• pp.1770-1776
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• 2011

In this study, a new method that can estimate ICG data from a subject's both hands to measure Cardiac Output under convenient sensor environment. With this aim, a grip-type electrode was implemented to measure ICG. To improve the accuracy of measurement, the regression equation was extracted using multiple bio-parameters and our result was compared with the thoracic ICG equipment(Physio Flow$^{(R)}$, PF104D, Manatec Biomedical, France), which is being used in clinics. The subjects consist of 26 men and 4 women(age in $22.0{\pm}3.32$). They are no cardiac disease. Parameters available for regression model were used gender, BMI, MBP, LVET, dZ/dt(max), distance between the measured electrodes, body impedance, and PTT. As a result of analyzing the ICG measurement value on thorax and both hands, the correlation with stroke volume, heart rate, and cardiac output was $R^2$=0.853, $R^2$=0.958 and $R^2$=0.899, respectively.

• 한국정보통신학회논문지
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• 제17권4호
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• pp.959-964
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• 2013

본 논문에서는 스완-간즈 카테터(Swan-Ganz catheter)를 사용하여 심장질환 중환자의 상태를 정확하게 파악하기 위해 기존의 모듈들보다 더 정밀한 데이터 측정이 가능한 모듈을 구현한다. 기존 방식은 차가운 수액을 심장에 주입하여 혈액의 온도변화와 회복시간을 측정하는 CO(Cardiac Output)를 측정하던 Bolus타입의 CO모듈이 존재하였지만, 지속적 환자 징후 관찰이 어렵다는 한계 때문에 현재는 대부분의 병원에서 사용하지 않는 상태이다. 이러한 한계를 극복하기 위해 지속적 심박출량 측정 플랫폼을 통해 효율적인 환자 징후관찰 및 상태파악이 가능 하도록 한다. 또한, 현재 기존 병원에서 심폐기능 이상 중환자의 징후관찰 및 상태파악을 위해 고가의 해외기기 도입으로 낭비되는 비용 문제를 해결하고 정밀한 데이터 수집으로 정확한 환자의 진단이 이루어 질 수 있도록 기존 모듈들의 문제점을 보완하였다.

• 대한수의사회지
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• 제6권1호
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• pp.11-14
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• 1962

The influence of pentobarbital sodium on the central nervous system has been studied extensively, but its effects on other systems have not received as much atention. In spite of the fact that vast amount of cardio-vascular research has been conducted on

• 대한간호학회지
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• 제40권3호
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• pp.433-441
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• 2010

Purpose: This study was performed to identify effects of pneumoperitoneum on hemodynamic changes of hypertensive patients undergoing laparoscopic colectomy under general anesthesia. Methods: Data collection was done from January 2 to June 10, 2008. Seventy-six patients, including 38 hypertensive patients, who had taken antihypertensive drugs more than 1 month and 38 normotensive patients undergoing laparoscopic colectomy were enrolled in this study. The hemodynamic parameters were heart rate (HR), mean arterial pressure (MAP) and cardiac output (CO) which were measured 7 times from before induction of anesthesia to 5 min after deflation of the pneumoperitoneum. Collected data were analyzed using Repeated Measures ANOVA and Bonferroni comparison method. Results: HR in the hypertensive group was significantly decreased at deflation of the pneumoperitoneum and 5 min after deflation of the pneumoperitoneum (p=.012). MAP in the hypertensive group was not different from the normotensive group (p=.756). CO in hypertensive group was significantly lower than normotensive group (p<.001) from immediately after pneumoperitoneum to 5 min after deflation of the pneumoperitoneum. Conclusion: The results indicate that pneumoperitoneum during laparoscopic surgery does not lead to clinically negative hemodynamic changes in heart rate, mean arterial pressure or cardiac output of hypertensive patients, who have taken antihypertensive drugs for more than 1 month.

• Journal of Chest Surgery
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• 제23권1호
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• pp.32-40
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• 1990

Surgical correction of congenital cardiac defects in infants and children with an elevated pulmonary arterial pressure or pulmonary vascular resistance carries a significant early postoperative mortality. And accurate assessments of cardiac output is critically important in these patients. From April 1988 through September 1989, serial measurements of cardiac index, ratio of pulmonary-systemic systolic pressure, ratio of pulmonary-systemic resistance, central venous pressure, left atrial pressure, and urine output during the first 48 hours after the cardiac operation were made in 30 congenital cardiac defects associated with pulmonary hypertension. Cardiac index showed significant increase only after 24 hour postoperatively and this low cardiac performance in the early postoperative period should be considered when postoperative management is being planned in the risky patients. There were no variables which showed any significant correlation with cardiac index. In 12 cases[40%], pulmonary hypertensive crisis developed during the 48 hours postoperatively, and they were treated with full sedation, hyperventilation with 100 % 0y and pulmonary vasodilator infusion. In all patient with preoperative pulmonary hypertension, surgical placement of a pulmonary artery catheter is desirable to allow prompt diagnosis of pulmonary hypertensive crisis and to monitor subsequent therapy.

• 대한전자공학회논문지
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• 제27권3호
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• pp.54-62
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• 1990

현재 임상에서 환자의 심박출량(cardiac output)을 측정하는데 널리 쓰이는 열희석법(thermodilution)은 카테터(catheter)의 심장주입에 따르는 위험성, 부작용 및 고도의 기술요구와 측정장비 및 비용의 고가, 측정 횟수의 제한, 환자의 고통등 여러 가지 문제점을 내포하고 있다. 한편 Electrical Impedance Cardiography는 이러한 열의석법의 단점들을 해결하고 나아가서 열희석법과는 달리 계속적으로 심박출량 뿐만 아니라 박동량(stroke volume) 및 심근육의 수축력등 심장의 기계적 기능을 감시할 수 있는 방법으로서, 외국에서는 널리 쓰이고 있고 이에 대한 연구도 활발한 상태이나 국내에서는 거의 보급이 안되어 있는 설정이다. 그리하여 본 연구에서는 이 새로운 분야의 국내 보급을 위하여 시제품을 완성하고 임상에서의 표준방법인 열희석법과 동시에 측정하여 기기의 정확성을 확인하였으며 운동 중에 운동부하 증가에 따른 심장기능의 변화도 측정하였다.