• 제목/요약/키워드: Capping Mechanism

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인라인 캐핑머신용 오실레이팅 암 기구부의 개발

  • 오상엽;배용환
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 2004년도 춘계학술대회 논문요약집
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    • pp.219-219
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    • 2004
  • 지금까지 식품, 약품 및 음료 산업 등에서 내용물을 충전 후 밀봉하기 위한 방법이 다양하게 개발되어 사용되고 있으며, 특히 뚜껑을 체결하는 인라인 캐핑머신(In-line capping machine)은 포장 공정에 필수적인 장치이다. 이와 같은 장치의 설계 시 고려되어야 할 사항으로서 작업 공정이 연속적인데 있다. 또한, 어느 한 제품을 용기에 채운 후 완전한 상품으로 조립하기까지, 캐핑머신의 신뢰성은 공정의 연속성과 생산성을 좌우하기 때문에 매우 중요한 요소이다.(중략)

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단당류와 이당류를 환원제로 합성한 은 나노입자의 Resazurin 산화환원반응 메커니즘 (Resazurin Redox Reaction Mechanism Using Silver Nanoparticles Synthesized with Monosaccharides and Disaccharides)

  • 박영주;장지웅
    • 공업화학
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    • 제31권3호
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    • pp.299-304
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    • 2020
  • 나노입자는 많은 화학합성에서 중요한 촉매역할을 한다. 촉매로 이용되는 나노입자를 합성할 때 colloidal synthesis를 많이 활용하고 있다. Colloidal synthesis를 이용해 나노입자를 합성할 경우 환원제, capping agent, shape directing agent 등이 촉매에 surface poisoning을 일으켜 촉매의 특성이 낮아질 수 있으며 합성 및 분리 과정 중 유해폐기물의 발생한다. Colloidal synthesis에서 사용되는 첨가제들의 양을 줄여 합성할 수 있는 새로운 나노입자를 합성법을 개발하여 은나노입자를 합성하였다. 결정화 기술을 이용하여 환원제, capping agent의 양을 줄일 수 있고 더욱이 합성된 나노입자 표면의 흡착되는 물질의 양을 줄여 surface poisoning을 낮출 수 있었다. 환원제로는 단당류와 이당류를 이용하여 surface poisoning이 거의 없는 은 나노입자는 resazurin의 산화환원 반응의 촉매로 이용할 수 있어 은 나노입자를 이용한 촉매 반응의 메커니즘을 분석하였다.

End-terminal Capping 효과가 아밀로이드 섬유의 기계적 특성에 미치는 영향 연구 (End-Terminal Capping Effect on Mechanical Property of Transthyretin (TTR105-115) Amyloid Fibril)

  • 최현성;이명상;나성수
    • 대한기계학회논문집A
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    • 제41권7호
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    • pp.621-627
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    • 2017
  • 다양한 신경성 퇴행 질병을 유발하는 아밀로이드 섬유의 기계적 특징에 대한 이해는 아밀로이드 성장 메커니즘에 직접 관련되어 있기 때문에 질병 역학적 관점에서 많은 연구 진행 되어 왔다. 최근 아밀로이드 섬유의 높은 물성 값과 자가 결합능력을 통해 새로운 재료로 이용 하려는 시도가 진행되고 있다. 본 연구에서는 심혈관 질환을 유발하는 transthyretin($TTR_{105-115}$)의 핵심 영역의 기계적 특성을 분자 동역학 전산 역학을 통해 평가했다. 특히 end-terminal capping의 효과가 $TTR_{105-115}$의 구조적 안정성에 미치는 영향을 평가했다. 인장모사 분자 동역학을 통해(steered molecular dynamics, SMD) 기계적 거동과 물성을 측정하였다. 재료의 기계적 특성에 영향을 주는 인자를 밝히고 자연 모사 재료로써의 활용 가능성에 대한 제시를 하였다.

Interspecies comparative morphological evaluation of the corneal epithelial stem cell niche: a pilot observational study

  • Popova, Petya;Malalana, Fernando;Biddolph, Simon;Ramos, Tiago;Parekh, Mohit;Chantrey, Julian;Ahmad, Sajjad
    • Journal of Veterinary Science
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    • 제23권4호
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    • pp.62.1-62.10
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    • 2022
  • Background: The corneal and limbal morphology relevant to corneal epithelial maintenance in ten different species was examined using histological methods. Objectives: The presence of a Bowman's layer, limbal epithelial cell, and superficial stromal morphology was examined in the following species to evaluate the differences in corneal thickness and epithelium: Java sparrows, frogs, macaws, spoonbills, red pandas, penguins, horses, Dobermans, orangutans, and humans. Methods: Corneal sections (4 ㎛) were obtained from ten ocular globes from three different animal classes: Aves, Amphibia, and Mammalia. All sections were stained with hematoxylin and eosin and periodic acid-Schiff reaction. After microscopy, all stained slides were photographed and analyzed. Results: Significant morphological differences in the corneal and limbal epithelia and their underlying stroma between species were observed. The number of corneal epithelial cell layers and the overall corneal epithelial thickness varied significantly among the species. The presence of a Bowman's layer was only observed in primates (orangutans and humans). Presumed supranuclear melanin caps were noted in four species (orangutans, macaws, red pandas, and horses) in the limbal basal epithelial layer (putative site of corneal epithelial stem cells). The melanin granules covered the apex of the cell nucleus. Conclusions: Supranuclear melanin capping has been described as a process within the epidermis to reduce the concentration of ultraviolet-induced DNA photoproducts. Similarly, there may be a relationship between limbal stem cell melanin capping as a protective mechanism against ultra-violet radiation.

간이충돌모델을 이용한 파일형 선박충돌방호공의 충돌거동 연구 (A Study on Behaviors of Pile Protective Structures by Simplified Collision Model)

  • 이계희
    • 대한토목학회논문집
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    • 제36권1호
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    • pp.31-38
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    • 2016
  • 논문에서는 파일형 선박충돌방호공의 주요 에너지 소산기구인 파일의 소성힌지와 선수변형에 대한 변형-에너지곡선을 산정하고 이를 이전 연구에서 개발된 간이 충돌모델에 적용하여 매개변수해석을 수행하였다. 고려된 매개변수는 슬래브의 질량, 파일의 수, 선박의 질량 및 충돌속도였으며 이들 매개변수를 변화시키면서 충돌거동을 분석하였다. 연구결과, 충진강관과 비충진강관의 에너지 소산거동이 차이를 파악했고, 슬래브의 관성질량을 조절하여 방호공의 충돌거동을 변화 시킬 수 있는 것으로 나타났다. 따라서 개발된 간이모델은 기본설계나 최적설계에 이용될 수 있을 것이다.

Compaction Simulator Study on Pectin Introducing Dwell Time

  • Kim, Hyun-Jo;Venkatesh, Gopi
    • Journal of Pharmaceutical Investigation
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    • 제35권4호
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    • pp.243-247
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    • 2005
  • Although many scientists have used pectin, its feasibility in terms of tablet manufacturability with a high speed machine has never been evaluated. Therefore, compactibility of different pectin types for large scale tableting operation has been evaluated. The compactibility behavior of powder pectins was studied by a compaction simulator. It was found that pectin on its own does not produce tablets of acceptable quality even at a punch velocity as low as 20 rpm (e.g. low tensile strengths, capping and lamination irrespective of applied compression force). Thus, dwell time was introduced and more hard compact was produced as relaxation time in die increases. It was concluded that frequent structural failure observed in both pectin types was due to lack of plastic deformation, poor compactibility and high elastic recovery.

변형 폴리올 공정에서 pH에 따라 합성된 Sn 나노입자의 형상 변화 및 형성기구 (Morphology and Formation Mechanism of Sn Nanoparticles Synthesized by Modified Polyol Process at Various pH Values)

  • 신용무;이종현
    • 한국재료학회지
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    • 제24권11호
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    • pp.578-584
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    • 2014
  • To synthesize Sn nanoparticles (NPs) less than 30 nm in diameter, a modified polyol process was conducted at room temperature using a reducing agent, and the effects of different pH values of the initial solutions on the morphology and size of the synthesized Sn NPs were analyzed. tin(II) 2-ethylhexanoate, diethylene glycol, sodium borohydride, polyvinyl pyrrolidone (PVP), and sodium hydroxide were used as a precursor, reaction medium, reducing agent, capping agent, and pH adjusting agent, respectively. It was found by transmission electron microscopy that the morphology of the synthesized Sn NPs varied according to the pH of the initial solution. Moreover, while the size decreased to 11.32 nm with an increase up to 11.66 of the pH value, the size increased rapidly to 39.25 nm with an increase to 12.69. The pH increase up to 11.66 dominantly promoted generation of electrons and increased the amount of initial nucleation in the solution, finally inducing the reduced-size of the Sn particles. However, the additional increase of pH dominantly induced a decrease of PVP by neutralization, which resulted in acceleration of the agglomeration by collisions between particles.

Interactions among Measles Virus Hemagglutinin, Fusion Protein and Cell Receptor Signaling Lymphocyte Activation Molecule (SLAM) Indicating a New Fusion-trimer Model

  • Zhang, Peng;Li, Lingyun;Hu, Chunlin;Xu, Qin;Liu, Xin;Qi, Yipeng
    • BMB Reports
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    • 제38권4호
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    • pp.373-380
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    • 2005
  • For measles viruses, fusion on the cell membrane is an important initial step in the entry into the infected cells. The recent research indicated that hemagglutinin firstly leads the conformational changes in the fusion protein then co-mediates the membrane fusion. In the work, we use the co-immunoprecipitation and pull-down techniques to identify the interactions among fusion protein, hemagglutinin and signaling lymphocyte activation molecule (SLAM), which reveal that the three proteins can form a functional complex to mediate the SLAM-dependent fusion. Moreover, under the confocal microscope, fusion protein and hemagglutinin protein can show the cocapping mediated by the SLAM. So fusion protein not only is involved in the fusion but also might directly interact with the SLAM to be a new fusion-trimer model, which might account for the infection mechanism of measles virus.

PET 말단에 대한 인계난연제의 라디칼계 부가반응 (1) - 비스페놀에이비스다이페닐포스페이트의 반응 - (Radical Addition Reaction of Phosphorous based Flame Retardant with End Groups of PET (1) - Reaction of Bisphenol A bis(diphenyl phosphate) -)

  • 김민관;김한도
    • 한국염색가공학회지
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    • 제24권1호
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    • pp.33-38
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    • 2012
  • In this study, to increase flame retardation of poly(ethylene terephthalate) (PET) in burning, bisphenol A bis(diphenyl phosphate) (BDP), a well known flame retardant containing phosphorous, was reacted on end groups of PET by radical pathway. End-capping mechanism of PET with BDP was suggested and confirmed by spectroscopic and thermal analysis. From 400 MHz $^{31}P$ solid state FT-NMR spectrum of end-capped PET (PET-BDP), phosphorus spectra peak in BDP was found at ca. -20 ppm. Furthermore, P-C bond stretching vibration peaks were found ca. $600cm^{-1}$ in FT-IR spectrums of PET-BDP. These results showed that BDP can be chemically added on end groups of PET by our method. Thermal characteristics of pure PET (pPET) and PET-BDP were measured and evaluated by TGA analysis. There was not significant changes in thermal characteristics of PET-BDP compared to that of pPET.