• Title/Summary/Keyword: Capping Mechanism

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인라인 캐핑머신용 오실레이팅 암 기구부의 개발

  • 오상엽;배용환
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2004.05a
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    • pp.219-219
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    • 2004
  • 지금까지 식품, 약품 및 음료 산업 등에서 내용물을 충전 후 밀봉하기 위한 방법이 다양하게 개발되어 사용되고 있으며, 특히 뚜껑을 체결하는 인라인 캐핑머신(In-line capping machine)은 포장 공정에 필수적인 장치이다. 이와 같은 장치의 설계 시 고려되어야 할 사항으로서 작업 공정이 연속적인데 있다. 또한, 어느 한 제품을 용기에 채운 후 완전한 상품으로 조립하기까지, 캐핑머신의 신뢰성은 공정의 연속성과 생산성을 좌우하기 때문에 매우 중요한 요소이다.(중략)

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Resazurin Redox Reaction Mechanism Using Silver Nanoparticles Synthesized with Monosaccharides and Disaccharides (단당류와 이당류를 환원제로 합성한 은 나노입자의 Resazurin 산화환원반응 메커니즘)

  • Park, Young Joo;Chang, Ji Woong
    • Applied Chemistry for Engineering
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    • v.31 no.3
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    • pp.299-304
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    • 2020
  • Nanoparticles play an important role as a catalyst in many chemical syntheses. Colloidal nanoparticles were usually synthesized with reducing, capping, and shape directing agents which induce surface poisoning of catalysts. A new green synthesis for silver nanoparticles was developed by utilizing less additives which could be a hazardous waste. A crystallization technique was employed to reduce the amount of reducing and capping agents during synthesis resulting in less surface poisoning of the nanoparticle. The synthesized Ag nanoparticles using monosaccharides and disaccharides as reducing agents could be used as a catalyst for the redox reaction of resazurin and the mechanism of the reaction using Ag nanoparticles was studied.

End-Terminal Capping Effect on Mechanical Property of Transthyretin (TTR105-115) Amyloid Fibril (End-terminal Capping 효과가 아밀로이드 섬유의 기계적 특성에 미치는 영향 연구)

  • Choi, Hyunsung;Lee, Myeongsang;Na, Sungsoo
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.41 no.7
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    • pp.621-627
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    • 2017
  • The understanding of the mechanical properties of amyloid fibers, which induce various neurodegenerative diseases, is directly related to the amyloid growth mechanism. Diverse studies have been performed on amyloid fibers from the viewpoint of disease epidemiology. Recently, attempts have been made to use amyloid fibers as new materials because of their notable mechanical properties and self-aggregation abilities. In this study, the mechanical properties of transthyretin (TTR105-115), which induces cardiovascular disease, were evaluated using a molecular dynamics (MD) simulation. In particular, the effect of the end-terminal capping on the structural stability of TTR105-115 was evaluated. The mechanical behavior and properties of TTR105-115 were measured by steered molecular dynamics (SMD). We clarified the factors affecting the mechanical properties of these materials and suggested the possibility of utilizing them as nature inspired materials.

Interspecies comparative morphological evaluation of the corneal epithelial stem cell niche: a pilot observational study

  • Popova, Petya;Malalana, Fernando;Biddolph, Simon;Ramos, Tiago;Parekh, Mohit;Chantrey, Julian;Ahmad, Sajjad
    • Journal of Veterinary Science
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    • v.23 no.4
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    • pp.62.1-62.10
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    • 2022
  • Background: The corneal and limbal morphology relevant to corneal epithelial maintenance in ten different species was examined using histological methods. Objectives: The presence of a Bowman's layer, limbal epithelial cell, and superficial stromal morphology was examined in the following species to evaluate the differences in corneal thickness and epithelium: Java sparrows, frogs, macaws, spoonbills, red pandas, penguins, horses, Dobermans, orangutans, and humans. Methods: Corneal sections (4 ㎛) were obtained from ten ocular globes from three different animal classes: Aves, Amphibia, and Mammalia. All sections were stained with hematoxylin and eosin and periodic acid-Schiff reaction. After microscopy, all stained slides were photographed and analyzed. Results: Significant morphological differences in the corneal and limbal epithelia and their underlying stroma between species were observed. The number of corneal epithelial cell layers and the overall corneal epithelial thickness varied significantly among the species. The presence of a Bowman's layer was only observed in primates (orangutans and humans). Presumed supranuclear melanin caps were noted in four species (orangutans, macaws, red pandas, and horses) in the limbal basal epithelial layer (putative site of corneal epithelial stem cells). The melanin granules covered the apex of the cell nucleus. Conclusions: Supranuclear melanin capping has been described as a process within the epidermis to reduce the concentration of ultraviolet-induced DNA photoproducts. Similarly, there may be a relationship between limbal stem cell melanin capping as a protective mechanism against ultra-violet radiation.

A Study on Behaviors of Pile Protective Structures by Simplified Collision Model (간이충돌모델을 이용한 파일형 선박충돌방호공의 충돌거동 연구)

  • Lee, Gye Hee
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.36 no.1
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    • pp.31-38
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    • 2016
  • In this paper, the deformation-energy curves of the plastic hinges and the vessel bow, which are the major energy dissipation mechanism of a pile protective structures, were estimated, and the parametric study was performed by using those curves to apply the simplified collision model which developed in the previous study. Considered parameters were the mass of slab, the number of piles, the mass of vessel and the collision speed. As results, the difference of energy dissipation mechanism of two pile types (filled and non-filled) were revealed, and the collision behaviors of the protective structures could be tuned by the control of the inertia mass of capping slab. Therefore the simplified collision model can be used in a primary design and optimal design.

Compaction Simulator Study on Pectin Introducing Dwell Time

  • Kim, Hyun-Jo;Venkatesh, Gopi
    • Journal of Pharmaceutical Investigation
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    • v.35 no.4
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    • pp.243-247
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    • 2005
  • Although many scientists have used pectin, its feasibility in terms of tablet manufacturability with a high speed machine has never been evaluated. Therefore, compactibility of different pectin types for large scale tableting operation has been evaluated. The compactibility behavior of powder pectins was studied by a compaction simulator. It was found that pectin on its own does not produce tablets of acceptable quality even at a punch velocity as low as 20 rpm (e.g. low tensile strengths, capping and lamination irrespective of applied compression force). Thus, dwell time was introduced and more hard compact was produced as relaxation time in die increases. It was concluded that frequent structural failure observed in both pectin types was due to lack of plastic deformation, poor compactibility and high elastic recovery.

Morphology and Formation Mechanism of Sn Nanoparticles Synthesized by Modified Polyol Process at Various pH Values (변형 폴리올 공정에서 pH에 따라 합성된 Sn 나노입자의 형상 변화 및 형성기구)

  • Shin, Yong Moo;Lee, Jong-Hyun
    • Korean Journal of Materials Research
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    • v.24 no.11
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    • pp.578-584
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    • 2014
  • To synthesize Sn nanoparticles (NPs) less than 30 nm in diameter, a modified polyol process was conducted at room temperature using a reducing agent, and the effects of different pH values of the initial solutions on the morphology and size of the synthesized Sn NPs were analyzed. tin(II) 2-ethylhexanoate, diethylene glycol, sodium borohydride, polyvinyl pyrrolidone (PVP), and sodium hydroxide were used as a precursor, reaction medium, reducing agent, capping agent, and pH adjusting agent, respectively. It was found by transmission electron microscopy that the morphology of the synthesized Sn NPs varied according to the pH of the initial solution. Moreover, while the size decreased to 11.32 nm with an increase up to 11.66 of the pH value, the size increased rapidly to 39.25 nm with an increase to 12.69. The pH increase up to 11.66 dominantly promoted generation of electrons and increased the amount of initial nucleation in the solution, finally inducing the reduced-size of the Sn particles. However, the additional increase of pH dominantly induced a decrease of PVP by neutralization, which resulted in acceleration of the agglomeration by collisions between particles.

Interactions among Measles Virus Hemagglutinin, Fusion Protein and Cell Receptor Signaling Lymphocyte Activation Molecule (SLAM) Indicating a New Fusion-trimer Model

  • Zhang, Peng;Li, Lingyun;Hu, Chunlin;Xu, Qin;Liu, Xin;Qi, Yipeng
    • BMB Reports
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    • v.38 no.4
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    • pp.373-380
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    • 2005
  • For measles viruses, fusion on the cell membrane is an important initial step in the entry into the infected cells. The recent research indicated that hemagglutinin firstly leads the conformational changes in the fusion protein then co-mediates the membrane fusion. In the work, we use the co-immunoprecipitation and pull-down techniques to identify the interactions among fusion protein, hemagglutinin and signaling lymphocyte activation molecule (SLAM), which reveal that the three proteins can form a functional complex to mediate the SLAM-dependent fusion. Moreover, under the confocal microscope, fusion protein and hemagglutinin protein can show the cocapping mediated by the SLAM. So fusion protein not only is involved in the fusion but also might directly interact with the SLAM to be a new fusion-trimer model, which might account for the infection mechanism of measles virus.

Radical Addition Reaction of Phosphorous based Flame Retardant with End Groups of PET (1) - Reaction of Bisphenol A bis(diphenyl phosphate) - (PET 말단에 대한 인계난연제의 라디칼계 부가반응 (1) - 비스페놀에이비스다이페닐포스페이트의 반응 -)

  • Kim, Min-Kwan;Ghim, Han-Do
    • Textile Coloration and Finishing
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    • v.24 no.1
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    • pp.33-38
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    • 2012
  • In this study, to increase flame retardation of poly(ethylene terephthalate) (PET) in burning, bisphenol A bis(diphenyl phosphate) (BDP), a well known flame retardant containing phosphorous, was reacted on end groups of PET by radical pathway. End-capping mechanism of PET with BDP was suggested and confirmed by spectroscopic and thermal analysis. From 400 MHz $^{31}P$ solid state FT-NMR spectrum of end-capped PET (PET-BDP), phosphorus spectra peak in BDP was found at ca. -20 ppm. Furthermore, P-C bond stretching vibration peaks were found ca. $600cm^{-1}$ in FT-IR spectrums of PET-BDP. These results showed that BDP can be chemically added on end groups of PET by our method. Thermal characteristics of pure PET (pPET) and PET-BDP were measured and evaluated by TGA analysis. There was not significant changes in thermal characteristics of PET-BDP compared to that of pPET.