• Journal of KIISE:Computing Practices and Letters
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• v.16 no.5
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• pp.596-600
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• 2010

This paper proposes hough transform-based semi-automatic vertex detection algorithm for object modeling on a mobile phone supporting touch-screens. The proposed algorithm shows fast processing time by searching the limited range of parameters for computing hough transform with a small range of ROI image. Moreover, the proposed algorithm removes bad candidates among the detected lines by selecting the two closest candidate lines from the position of user's input. After that, it accurately detects an interesting vertex without additionally required interactions by detecting an intersection point of the two lines. As a result, we believe that the proposed algorithm shows a 1.4 pixel distance error on average as a vertex detection accuracy under such conditions as a 5.7 pixel distance error on average as an inaccurate input.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.2
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• pp.157-162
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• 2018

Objective: The aim of this study is to identify single nucleotide polymorphisms (SNPs) and genes related to pig IMF and estimate the heritability of intramuscular fat content (IMF). Methods: Genome-wide association study (GWAS) on 704 inbred Berkshires was performed for IMF. To consider the inbreeding among samples, associations of the SNPs with IMF were tested as random effects in a mixed linear model using the genetic relationship matrix by GEMMA. Significant genes were compared with reported pig IMF quantitative trait loci (QTL) regions and functional classification of the identified genes were also performed. Heritability of IMF was estimated by GCTA tool. Results: Total 365 SNPs were found to be significant from a cutoff of p-value <0.01 and the 365 significant SNPs were annotated across 120 genes. Twenty five genes were on pig IMF QTL regions. Bone morphogenetic protein-binding endothelial cell precursor-derived regulator, forkhead box protein O1, ectodysplasin A receptor, ring finger protein 149, cluster of differentiation, tyrosine-protein phosphatase non-receptor type 1, SRY (sex determining region Y)-box 9 (SOX9), MYC proto-oncogene, and macrophage migration inhibitory factor were related to mitogen-activated protein kinase pathway, which regulates the differentiation to adipocytes. These genes and the genes mapped on QTLs could be the candidate genes affecting IMF. Heritability of IMF was estimated as 0.52, which was relatively high, suggesting that a considerable portion of the total variance of IMF is explained by the SNP information. Conclusion: Our results can contribute to breeding pigs with better IMF and therefore, producing pork with better sensory qualities.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.23
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• pp.10325-10328
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• 2015

RASSF1A, regarded as a candidate tumor suppressor, is frequently silenced and inactivated by methylation of its promoter region in many human tumors. However, the association between RASSF1A promoter methylation and lung cancer risk remains unclear. To provide a more reliable estimate we conducted a meta-analysis of cohort studies to evaluate the potential role of RASSF1A promoter methylation in lung carcinogenesis. Relevant studies were identified by searches of PubMed, Web of Science, ProQest and Medline databases using the following key words: 'lung cancer or lung neoplasm or lung carcinoma', 'RASSF1A methylation' or 'RASSF1A hypermethylation'. According to the selection standard, 15 articles were identified and analysised by STATA 12.0 software. Combined odds ratio (OR) and 95% confidence interval (CI) were used to assess the strength of the association between RASSF1A promoter methylation and lung cancer risk. A chi-square-based Q test and sensitivity analyses were performed to test between-study heterogeneity and the contributions of single studies to the final results, respectively. Funnel plots were carried out to evaluate publication bias. Overall, a significant relationship between RASSF1A promoter methylation and lung cancer risk (OR, 16.12; 95%CI, 11.40-22.81; p<0.001) with no between-study heterogeneity. In subgroup analyses, increased risk of RASSF1A methylation in cases than controls was found for the NSCLC group (OR, 13.66, 95%CI, 9.529-19.57) and in the SCLC group (OR, 314.85, 95%CI, 48.93-2026.2).

• Journal of Microbiology and Biotechnology
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• v.24 no.12
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• pp.1728-1735
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• 2014

Scrub typhus, caused by infection with Orientia tsutsugamushi, is a mite-borne zoonotic disease endemic to the Asian-Pacific region. In Korea, the incidence of this disease has increased with climate changes, and over 10,000 cases of infection were reported in 2013. Although this infection is treatable with antibiotics such as doxycycline and azithromycin, an effective prophylactic vaccine against O. tsutsugamushi would be more desirable for preventing scrub typhus in endemic areas. In this study, we investigated the 56-kDa type-specific antigen (TSA56), which is a major outer membrane protein of O. tsutsugamushi, as a vaccine candidate. Intranasal immunization of recombinant TSA56 (rec56) induced a higher level of TSA56-specific IgG than that induced by intramuscular immunization of tsa56-expressing DNA (p56). Both types of immunization induced a cell-mediated immune response to TSA56, as demonstrated by the splenic cell proliferation assay. Mice immunized with p56, followed by rec56 plus heat-labile enterotoxin B subunit from E. coli, had a stronger protection from a homologous challenge with the O. tsutsugamushi Boryong strain than with other combinations. Our preliminary results suggest that an effective human vaccine for scrub typhus can include either recombinant TSA56 protein or tsa56-expressing DNA, and provide the basis for further studies to optimize vaccine performance using additional antigens or different adjuvants.

• Journal of Navigation and Port Research
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• v.31 no.6
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• pp.545-553
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• 2007

Due to the change of global production network, the establishment of new strategy in Korea ports is required Especially, the trade pattern has been mainly concentrated in Northeast Asia region according to economic growth of the Asia including China, Japan, and Korea. Hence, Korea major ports with the competition of price and service has to meet the need of Northeast port alliance and has to compete against other countries in variable trade environment. Therefore, the objective of this study is to propose a port alliance strategy in order to promote the transshipment of Korea major ports such as Pusan port and Gwangyang port. In order to establish the logistics business model in the ports, we provided the direction of the Northeast port alliance and candidate ports in China and Japan.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.39 no.7
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• pp.585-595
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• 2011

The flow characteristics of synthetic jet depending on rectangular and circular jet exit configuration are investigated using numerical computation with cross flow. In rectangular slot, synthetic jet generates the strong vortex but supplies fewer momentum and effectiveness of flow control is reduced along flow direction. In circular slot, regular vortex is formed from slot center to end. It affects the wider region than rectangular slot. The distribution of wall shear stress is considered in order to indicate the effectiveness of flow control device for flow separation delay. Consequently, circular slot is a more suitable candidate for delaying flow separation. In order to derive the optimal shape of a circular slot exit, hole gap and diameter that affect the flow structure and flow control were analyzed. As a result, consider the hole diameter and gap of circular slot exit design, effectiveness of the flow control can be increased.

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.700-705
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• 2005

The purpose of this project is the derivation and development of techniques for the new estimation of robustness for the systems having uncertainties. The basic ideas to analyze the system which is the originally nonlinear is Lyapunov direct theorems. The nonlinear systems have various forms of terms inside the system equations and this investigation is confined in the form of bounded uncertainties. Bounded means the uncertainties are with same positive/negative range. The number of uncertainties will be the degree of freedoms in the calculation of the stability region. This is so called the robustness bounds. This proposition adopts the theoretical analysis of the Lyapunov direct methods, that is, the sign properties of the Lyapunov function derivative integrated along finite intervals of time, in place of the original method of the sign properties of the time derivative of the Lyapunov function itself. This is the new sufficient criteria to relax the stability condition and is used to generate techniques for the robust design of control systems with structured perturbations. Using this relaxing stability conditions, the selection of Lyapunov candidate function is of various forms. In this paper, the quadratic form is selected. this generated techniques has been demonstrated by recent research interest in the area of robust control design and confirms that estimation of robustness bounds will be improved upon those obtained by results of the original Lyapunov method. In this paper, the symbolic algebraic procedures are utilized and the calculating errors are reduced in the numerical procedures. The application of numerical procedures can prove the improvements in estimations of robustness for one-and more structured perturbations. The applicable systems is assumed to be linear with time-varying with nonlinear bounded perturbations. This new techniques will be extended to other nonlinear systems with various forms of uncertainties, especially in the nonlinear case of the unstructured perturbations and also with various control method.

• Journal of the Korean Magnetics Society
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• v.4 no.3
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• pp.244-248
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• 1994

Magnetic and Magneto-optical characteristics of NdTbFeCo alloy films and NdTbFeCo/TbFeCo double-layered films have been investigated. It was observed that the Kerr rotation(${\theta}_{k}$) in the short wavelength region increased and the coercivity decreased as the substitutional amount of Nd for Tb in NdTbFeCo film at the constant FeCo content. In spite of the increased ${\theta}_{k}$, a small coercivity of NdTbFeCo film made this medium unsuitable for magneto-optical recording medium at short wavelength. An effort was made to improve coercivity by exchange coupling with TbFeCo film of high coercivity. In the exchange-coupled $Nd_{16.9}Tb_{15.2}Fe_{50.4}Co_{17.5}(150\;{\AA})/Tb_{21.1}Fe_{65.0}Co_{13.9}(300\;{\AA})$ double-layered film, the magnetization reversal switching field and the Kerr rotation angle were increased to about 6.0 KOe and $0.32^{\circ}$ at 500 nm, respectively. This result indicates that exchange-coupled NdTbFeCo/TbFeCo film can be a promising candidate for agneta-optical rerding medium short wavelenhth.

• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.5
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• pp.137-151
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• 2014

This paper proposes a method of detecting object of interest(OOI) in general natural images. OOI is subjectively estimated by human in images. The vision of human, in general, might focus on OOI. As the first step for automatic detection of OOI, candidate regions of OOI are detected by using a saliency map based on the human visual perception. A saliency map locates an approximate OOI, but there is a problem that they are not accurately segmented. In order to address this problem, in the second step, an exact object region is automatically detected by combining graph-based image segmentation and skeletonization. In this paper, we calculate the precision, recall and accuracy to compare the performance of the proposed method to existing methods. In experimental results, the proposed method has achieved better performance than existing methods by reducing the problems such as under detection and over detection.

• Journal of the Korean Institute of Intelligent Systems
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• v.14 no.4
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• pp.506-511
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• 2004

Biometrics is getting more and more attention in recent years for security and other concerns. So far, only fingerprint recognition has seen limited success for on-line security check, since other biometrics verification and identification systems require more complicated and expensive acquisition interfaces and recognition processes. Hand-Geometry has been used for biometric verification and identification because of its acquisition convenience and good performance for verification and identification performance. Hence, it can be a good candidate for online checks. Therefore, this paper proposes a Hand-Geometry recognition system based on geometrical features of hand. From anatomical point of view, human hand can be characterized by its length, width, thickness, geometrical composition, shapes of the palm, and shape and geometry of the fingers. This paper proposes thirty relevant features for a Hand-Geometry recognition system. However, during experimentation, it was discovered that length measured from the tip of the finger was not a reliable feature. Hence, we propose a new technique based on Genetic Algorithm for extraction of the center of nail bottom, in order to use it for the length feature.