• KCI Concrete Journal
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• 제12권2호
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• pp.3-10
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• 2000

A computer program, named NEO-PCBRG, for the analysis and design of prestressed con-crete(PSC) bridges was developed using the finite element method. NEO-PCBRG can predict the response of PSC bridges throughout the various stages of construction and service. NEO-PCBRG has both pre- and post-processing capabilities. Pre-processing refers to all the neces- sary steps required to prepare a virtual prototype, more commonly termed a varied model for analysis. Post-processing here stands for the step in which the results from the analysis are reviewed and interpreted. In order to allow for the easy and convenient execution of the entire procedure, NEO-PCBRG was developed using computer graphics in the Visual Basic pro- gramming language. In conclusion, this study presents a new software architecture for analy-sis using the user-oriented design technique.

• 대한간호학회지
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• 제23권1호
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• pp.42-55
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• 1993

Computerization has been applied in most areas of health care in recent years. But computerized standardized nursing care plans have not yet been adequately developed even though they can significantly contribute to an improvement in the quality of nursing care. Therefore, this study was done to develop computerized nursing care plans. For this purpose, the study had the following objectives ; 1) to develop a computerized program for standardized nursing care plans which include defining characteristics, relating factors, expected out-comes and nursing interventions 2) to test applicability of the computerized pro-grams to the actual clinical situation of the clinical nurse. Application of the system development life cycle by davis was used as the study methodology. There are five stages in this method : strategy planning development, system analysis, system design, system practice and system evaluation. The first four steps in this methodology were used in this project. Two clinical nurses were selected to apply this computerized program in the clinical situation. The results of the study are as follows ; 1) Ten standardized nursing care plans including defining characteristics, relating factors, expected outcomes and nursing interventions which had been proven to have validity in the clinical setting were computerized using the Foxbase Program. 2) These programs were applied to the actual clinical situation by two clinic친 nurses working at Severance Hospital. For further study, continuous revision should be done by the users. Evaluation related to the utilization of the program should also be done.

• 한국식생활문화학회지
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• 제28권6호
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• pp.562-575
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• 2013

Century-old nutrition and health concepts can be revived and applied in the modern age in the forms of newly developed menus, recipes, and lifestyle education. Current medical nutrition therapy concepts were first described in the Chosun Dynasty (1392-1897) in Korea based on the philosophy that food and medicine originate from the same source, which is known as 'food as medicine'. Recognizing the importance of culture, tradition, local diet, and lifestyle on health and medical nutrition therapy, we tried to rediscover traditional Korean approaches towards food consumption and nutrition through systematic review of the literature and developed contemporary menus accordingly. The medical nutrition therapy prescriptions described in 'Shikryochanyo' (1460) by the Chosun Dynasty's royal physician Soonyi Jeao cover 45 different diseases. In this project, we developed contemporary menus for those disease models that are most prevalent in modern society. Menus developed with foods that are readily available today were evaluated for their nutritional content and adequacy using a computer-aided nutritional analysis program (CAN pro 3.0, developed by the Korean Nutrition Society for comparison with RDA for Koreans). Therefore, century-old nutrition and health concepts can be revived and applied in modern society as newly developed menus recipes and lifestyle education.

• 한국전통조경학회지
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• 제35권1호
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• pp.83-89
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• 2017

제주올레는 2007년 제1코스 개장을 시작으로 2017년 2월 현재 총26개 코스가 제주전역에 퍼져있으며 매년 1백 만 명 이상의 관광객이 제주 올레를 걷기 위해 제주를 방문하고 있다. 제주올레는 환경문제가 큰 사회적 문제로 대두되는 현 시점에서 도보 여행으로서 제주의 자연과 생태계를 지킬 수 있는 대표적인 친환경 여행 형태라는 점에서 큰 주목을 받고 있다. 지금까지 제주올레에 대한 연구는 제주방문 관광객 위주로 진행되어 제주올레의 또 하나의 주인이라고 할 수 있는 제주도민의 제주 올레 여행에 대한 연구는 미비한 실정이다. 이에 본 연구에서는 제주 방문 올레 도보여행자들과 제주도민을 함께 연구 대상으로 선정하여 제주올레에 대한 여행 행태와 여행 만족도, 친환경 행동에 차이가 있는지 비교하는 것을 그 목적으로 하였다. 2016년 12월부터 2017년 2월까지 수집한 총 290부의 설문지를 분석한 결과, 제주도민은 제주방문 올레 도보 여행자에 비해 평균 동반 인원수가 더 많은 반면 제주올레 여행 만족도와 친환경 행동 점수는 제주방문 올레 도보 여행자에 비해 낮은 것으로 나타났다. 특히 제주도민이 제주방문 올레도보 여행자보다 상대적으로 낮은 친환경 행동을 보인 본 연구 결과는 제주전체의 환경문제와 연관되는 것으로 친환경 행동을 향상시키기 위한 제주도민 대상의 지속적인 환경 교육 프로그램과 홍보가 필요한 때이다.

• 식품보건융합연구
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• 제6권2호
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• pp.23-26
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• 2020

Active and therapeutic sport recovery is becoming a popular and important component in approving performance for pro and recreational athletes alike. It is also helping in the realm of injury prevention. In the search of finding modalities that are widely effective, natural, and safe, acupuncture is a viable and cost-effective treatment for helping athletes achieve this goal. More direct related research is needed, but testimonials from pro athletes and the body of research that currently exists provides powerful evidence on acupunctures ability to help with enhancing recovery. Specializing in acupuncture and exercise science, Chris integrates acupuncture into musculoskeletal rehabilitation therapy or fitness training for pain modulation, speedy recovery, and enhanced performance. Clients can choose to focus on one-on-one corrective exercise therapy, manual and massage therapy, or acupuncture. However, for best results, Chris recommends all three. Other modalities that he uses in therapy are acu-taping, herbal therapy, nutrition supplementation, cupping, guasha, and stretching techniques. The corrective exercise component is one-on-one body balancing management, focusing on strength and conditioning, post physical rehab - exercise therapy, integrative sport specific exercise, weight loss, core strengthening, dynamic lumbar stabilization, active recovery techniques, and myo-fascial release techniques. The acupuncture component focuses on sport injuries, myofascial pain, peripheral neuropathy, arthritis, facial rejuvenation, stress, smoking cessation, addiction detoxification program, weight management, sport recovery and performance.

• The Journal of Asian Finance, Economics and Business
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• 제9권2호
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• pp.255-260
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• 2022

SME sector's success also depends on its employees' job satisfaction as satisfied employees are likely to be more productive at the workplace and positively enhance SME business performance. Small and medium firms are the heart of the economy, and employees are the main and valuable asset for the SME firms. If SME business managers can increase employee satisfaction, then SMEs' performance will also increase in the future. Hence, the current study aims to determine the job satisfaction of SME employees by analyzing the impact of job training (JT) and promotion (PRO) opportunities on employee job satisfaction. Purposive sampling is applied in the study, and 202 SME employees have participated as sample respondents. The final sample size is n = 202. SPSS 26.0 version is used to analyze the hypotheses. The study findings show that both job training (JT) and promotion (PRO) have a positive effect on SME employee job satisfaction. It does indicate that SME managers need to provide necessary training programs and timely promotion to their current working employees to keep them satisfied with their job. Promotion and effective job training will certainly enhance employees' job satisfaction. The study has also offered a few strategic implications for SME business managers.

• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.1649-1654
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• 2016

Tea derived from the leaves and buds of Camellia sinensis (Theaceae) is consumed worldwide. Green tea contains various components with specific health-promoting effects, and is believed to exert protective effects against diseases including cancer, diabetes and hepatitis, as well as obesity. Of the various tea components, the polyphenol catechins have been the subject of extensive investigation and among the catechins, (-)-epigallocatechin gallate has the strongest bioactivity in most cases. Our research group has postulated that hepatocyte nuclear factor-$4{\alpha}$, sterol regulatory element-binding proteins, and tumor necrosis factor-${\alpha}$ are targets of green tea constituents including (-)-epigallocatechin gallate for their anti-diabetes, anti-obesity, and anti-hepatitis effects, respectively. Published papers were reviewed to determine whether the observed changes in these factors can be correlated with anti-cancer effects of green tea. Two major action mechanisms of (-)-epigallocatechin gallate have been proposed; one associated with its anti-oxidative properties and the other with its pro-oxidative activity. When reactive oxygen species are assumed to be involved, our findings that (-)-epigallocatechin gallate downregulated hepatocyte nuclear factor-$4{\alpha}$, sterol regulatory element-binding proteins, and tumor necrosis factor-${\alpha}$ may explain the anti-cancer effect of green tea as well. However, further studies are required to elucidate which determinant directs (-)-epigallocatechin gallate action as an anti-oxidant or a pro-oxidant for favorable activity.

• 인간식물환경학회지
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• 제22권6호
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• pp.611-619
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• 2019

This study was conducted to investigate changes in the mental functions of the elderly in nursing facilities affected by a horticultural therapy program based on validation therapy. To meet the purpose, we conducted a horticultural therapy program based on validation therapy with 58 elderly participants (average age 79.12±6.84, men and women) once a week, 50 minutes per session, in a total of 10 sessions. Participants were divided into the control and experimental group with convenience sampling. The program was carried out from March 15 to November 22, 2018. Vibraimage 8 pro(ELSYS, 2014) is a recent, psychologically based, emotional-recognition visual imaging technology that measures pixels microvibration in terms of digital frequency and amplitude parameters. To examine the effects of the horticultural therapy program based on validation therapy, Vibraimage was used to assess aggression, stress, tension, suspect, balance, charm, energy, self-regulation, inhibition, neuroticism and positive, negative, physiological domains of mental functions before and after program. As a result, the mean score of the positive domain in the control group significantly decreased from 63.89±5.09 to 60.74±5.48, but it decreased without statistical significance in the experimental group from 63.98±5.45 to 61.39±6.02. The mean score of neuroticism in the experimental group significantly decreased from 31.64±10.94 to 22.87±13.79. Moreover, the mean score of the physiological domain in the experimental group also significantly decreased from 25.08±6.27 to 19.42±8.80. Accordingly, horticultural therapy program based on validation therapy can be utilized as a program to promote mental health, especially maintaining positive mental health function of the eldery, helping those who live in long-term care facilities enjoy a happier life more happier.

• BMB Reports
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• 제43권1호
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• pp.57-61
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• 2010

Activator protein-1 can induce either cell survival or death, which is controlled by opposing effects of different Jun members. It is generally accepted that c-Jun is pro-apoptotic, but that JunD is anti-apoptotic in stress-exposed cells. Additionally, although there are reports suggesting that JunB plays a protective role, its role in stress-induced apoptosis remains unclear. Here, we investigated the role of JunB in $H_2O_2$-induced cell death using cells that over-expressed the protein or were transfected with si-JunB. Inhibition of JunB expression accelerated $H_2O_2$-mediated loss of mitochondrial membrane potential (MMP) and cytotoxicity. Conversely, over-expression of JunB protein led to significant inhibition of the MMP loss and cell death. The increase in JunB expression also attenuated nuclear relocation of apoptosis-inducing factor and mitochondrial Bcl-2 reduction that occurred following $H_2O_2$ exposure. These results suggest that JunB can signal survival against oxidant-mediated cell death by suppressing mitochondrial stress.

• 생명과학회지
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• 제21권11호
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• pp.1549-1557
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• 2011

TRAIL은 다양한 암세포에서 apoptosis를 유발하는 것으로 알려져 있으나 간암세포를 포함한 일부 암세포에서 TRAIL 저항성이 획득된 것으로 보고되어지고 있다. 대두의 대표적인 생리활성 물질인 isoflavonoid계열 genistein은 이미 많은 암세포에서 apoptotic 효능을 가진 것으로 알려져 있으나 TRAIL에 의한 apoptosis 유도에 미치는 영향과 기전에 대한 연구는 여전히 미비한 실정이다. 본 연구에서는 TRAIL 저항성을 가진 Hep3B 간암세포에서 TRAIL에 의한 apoptosis 유도를 genistein이 더욱 상승시킬 수 있음을 보고하고자 한다. 본 연구의 결과에 의하면, Hep3B 세포에 세포독성을 보이지 않는 범위의 genistein에 의한 TRAIL 유도 apoptosis 상승효과는 미토콘드리아의 기능 손상과 연관성이 있었다. 또한 genistein과 TRAIL 복합처리에 의한 apoptosis 유도는 p38 MAPK 활성 저하로 더욱 상승하였으며, 이는 Bid의 truncation 증가, pro-apoptotic 단백질인 Bax의 발현 증가와 anti-apoptotic Bcl-2의 발현 감소 및 미토콘드리아에서 세포질로의 cytochrome c 유출의 증가와 연관성이 있었다. 또한 p38 MAPK 억제제는 genistein 및 TRAIL 복합처리에 의한 caspase의 활성 증가와 PARP 단백질의 단편화를 촉진시켰으며, 이는 미토콘드리아의 기능적 손상 증가에 의한 것임을 알 수 있었다. 따라서 본 연구의 결과는 genistein이 TRAIL에 의한 apoptosis 유도를 효과적으로 증가시킬 수 있으며, 이러한 과정이 p38 MAPK 의존적으로 이루어짐을 알 수 있었다.