• 제목/요약/키워드: Calibration verification

검색결과 279건 처리시간 0.023초

검량보정 검증의 실험적 적합성에 대한 연구 -치료적 약물검사를 중심으로- (An Empirical Validation Study for Calibration Verification in TDM Test)

  • 장상우;김남용;최호성;박용원;추경복;윤근영;박병옥
    • 대한임상검사과학회지
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    • 제37권1호
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    • pp.1-7
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    • 2005
  • The purpose of this study was to verify (i) a consistent calibration verification for the assessment of method linearity and (ii) calibration agreement with calibration settings. We validated calibration verification through method linearity with different lot number of individual calibrators that span the working range for 9 tests except salicylate with control sample in test. We evaluated that it covered broad analyte range to assay from near zero to the top of the measuring range with 5 or 6 points every three times for 10 analytes in TDM test. Target values were plotted on X-axis with assigned or observed values on the Y-axis. Working range were as follows. Calibration verification of the measuring range (maximum to minimum values) has been validated asetaminophen 0.1 to $304.6_{\mu}g/mL$, salicylate 0 to $1005_{\mu}g/mL$, valproic acid 3.2 to $154.19_{\mu}g/mL$, digoxin 0.17 to 5.65 ng/mL, vancomycine 1.3 to $80.51_{\mu}g/mL$, carbarmazepine 0.1 to $22.3_{\mu}g/mL$, phenytonin 0.6 to $40.21_{\mu}g/mL$, theophyline 0.2 to $40.21_{\mu}g/mL$, primidone 0 to $24.07_{\mu}g/mL$, phenobarbital 0.6 to $60.0_{\mu}g/mL$. Drawing a straight line through five or six points of these data showed good linearity. We are sure that it is important to assess the calibration verification of a test method to ascertain the lowest and highest test results that are reliable.

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Calibration and Verification of a Tidal Prism Eutrophication Model for the Lynnhaven Bay (U.S.A)

  • PARK Kyeong;KUO Albert Y.
    • 한국수산과학회지
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    • 제30권6호
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    • pp.964-973
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    • 1997
  • A tidal prism eutrophication model, an one-dimensional intertidal model, is developed to study water quality conditions at small coastal basins and tidal creeks. The model simulates the physical transport processes using the concept of tidal flushing. The concept is simple and straightforward, and thus is ideal for small coastal basins with complex geometry. The model, having twenty-four state variables in the water column, simulates salinity, temperature, dissolved oxygen, three algal groups, and the cycles of carbon, nitrogen, phosphorus and silica. The model is applied to the Lynnhaven Bay, a small coastal basin of Chesapeake Bay in U.S.A. The model is calibrated using the field data collected in 1994, and then is verified using the independently collected data in 1980. The model overall gives a good reproduction of the field data, partly owing to the data collected from the field surveys specifically designed for the model application. This paper presents the procedure, and the results of the model calibration and verification.

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천수만과 인근연안에서 수역학모델의 보정 및 검증 (Calibration and Verification of a Hydrodynamic Model in Chunsu Bay and Adjacent Coastal Water)

  • Kyeong Park;Jeong Hwan Oh
    • 한국해안해양공학회지
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    • 제10권3호
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    • pp.109-119
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    • 1998
  • 수평 2차원 POM (Princeton Ocean Model)을 바닥마찰과 개방경계조건에 대하여 수정하고, 간석지를 모의하기 위하여 wetting-and-drying 기법을 첨가하여 천수만과 인근연안에 적용하였다. 연구해역의 주된 기작인 조석에 의한 해수유통만을 고려하였다. 본 논문은 천수만 해역에서의 모델 보정과 검증 절차 및 결과를 제시한다. 조석표의 평균 조석 특성을 이용하여 모델영역 전반에 걸쳐 진폭과 위상을 포함하는 조석파의 전파에 대하여 모델을 보장하였고, 보정 결과가 조석파를 잘 재현하였다. 보정된 모델을 1995년 여름 관측된 해수면 변위와 유속에 대한 시계열 자료를 이용하여 검증하였고, 검증 결과가 조석 및 조류를 잘 재현하였다. 보정 및 검증 결과가 본 모델이 천수만 해역에서 조석 현상을 잘 재현할 수 있음을 보여주었다

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Study of statistical distribution for four-port TEM cell

  • Jeon, Sangbong;Kwon, Jong-Hwa
    • Journal of Multimedia Information System
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    • 제1권2호
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    • pp.127-132
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    • 2014
  • The transverse electromagnetic (TEM) cells are widely used for electromagnetic compatibility (EMC) testing and field probe calibrations. We propose the verification of TEM mode with statistical method using a four-port TEM cell. The verification results are compared with Normal, Rayleigh, and Gamma distribution. As a result, the 75 % quantile of the Rayleigh distribution is excellent agreement with the true quantiles for a number of calibration points.

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초음파 도플러 유속계 교정 시설 현황 (Analysis of Calibration Facilities for Acoustic Doppler Current Profilers (ADCPs))

  • 이정한;황근춘;김은수
    • Ocean and Polar Research
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    • 제33권2호
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    • pp.171-183
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    • 2011
  • Despite technological developments and application advances of Acoustic Doppler Current Profilers (ADCPs), no standard procedure has been adopted or accepted for calibration of ADCPs. Limitations of existing facilities for calibrating ADCPs, the complexity of ADCP instruments, and rapid changes in ADCP technology are some of the reasons why a standard procedure has not been adopted. However, there is increasing realization of the need for effective Quality Assurance (QA) and as part of that the importance of standardized calibration. In this study, the significance of calibration and QA plans for ADCPs is discussed and the calibration facilities for ADCPs at home and abroad are reported. Furthermore, the method for calibrating ADCPs using a towed car and its limitations are discussed. This study contributes to discussions surrounding the establishment of standard procedures for calibrating ADCPs and QA plans, and the construction of calibration facilities in the future.

SWAT 모형을 이용한 토양유실량 저감효과 모의 (Simulation of the Reduction Effect of Soil Loss Using SWAT Model)

  • 정진권;김환기
    • 환경영향평가
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    • 제17권4호
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    • pp.243-253
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    • 2008
  • The purpose of this study was to simulate the reduction effect of soil loss in the Yongdam reservoir watershed using SWAT model. To evaluate accuracy for flow and sediment yield of SWAT model, calibration was performed for the period from Jan. 2002 to Dec. 2003, and the verification for Jan. 2005 to Dec. 2005. The calibration and the verification were carried out using data observed at the Cheoncheon gaging station. The $R^2$ and EI values in terms of a flow were 0.8 and 0.78 respectively for calibration, whereas they for verification were 0.88 and 0.86 respectively. In terms of a sediment yield, they were 0.7 and 0.48 respectively for calibration, whereas for verification were 0.64 and 0.54 respectively. As a results from model simulation, annual mean soil loss rates in terms of forest, paddy and upland were 0.02 ton/ha/yr, 0.15 ton/ha/yr and 7.58 ton/ha/yr, respectively. The results show that the land use type of a upland has more significant impact on a total soil loss as well as a sediment yield than other types of land use. The sediment delivery ratio was determined to be about 0.35. In this study 2 land cover change scenarios for upland area were considered. These scenarios were used an input to SWAT model in order to evaluate their impact on soil loss and sediment delivery. The results show that a reduction of the upland area would reduce the soil loss and sediment yield.

복합형 유역모델 STREAM의 개발(II): 모델의 시험 적용 (Development of a Hybrid Watershed Model STREAM: Test Application of the Model)

  • 조홍래;정의상;구본경
    • 한국물환경학회지
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    • 제31권5호
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    • pp.507-522
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    • 2015
  • In this study, some of the model verification results of STREAM (Spatio-Temporal River-basin Ecohydrology Analysis Model), a newly-developed hybrid watershed model, are presented for the runoff processes of nonpoint source pollution. For verification study of STREAM, the model was applied to a test watershed and a sensitivity analysis was also carried out for selected parameters. STREAM was applied to the Mankyung River Watershed to review the applicability of the model in the course of model calibration and validation against the stream flow discharge, suspended sediment discharge and some water quality items (TOC, TN, TP) measured at the watershed outlet. The model setup, simulation and data I/O modules worked as designed and both of the calibration and validation results showed good agreement between the simulated and the measured data sets: NSE over 0.7 and $R^2$ greater than 0.8. The simulation results also include the spatial distribution of runoff processes and watershed mass balance at the watershed scale. Additionally, the irrigation process of the model was examined in detail at reservoirs and paddy fields.

Uncertainty Assessment: Relative versus Absolute Point Dose Measurement for Patient Specific Quality Assurance in EBRT

  • Mahmood, Talat;Ibrahim, Mounir;Aqeel, Muhammad
    • 한국의학물리학회지:의학물리
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    • 제28권3호
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    • pp.111-121
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    • 2017
  • Verification of dose distribution is an essential part of ensuring the treatment planning system's (TPS) calculated dose will achieve the desired outcome in radiation therapy. Each measurement have uncertainty associated with it. It is desirable to reduce the measurement uncertainty. A best approach is to reduce the uncertainty associated with each step of the process to keep the total uncertainty under acceptable limits. Point dose patient specific quality assurance (QA) is recommended by American Association of Medical Physicists (AAPM) and European Society for Radiotherapy and Oncology (ESTRO) for all the complex radiation therapy treatment techniques. Relative and absolute point dose measurement methods are used to verify the TPS computed dose. Relative and absolute point dose measurement techniques have a number of steps to measure the point dose which includes chamber cross calibration, electrometer reading, chamber calibration coefficient, beam quality correction factor, reference conditions, influences quantities, machine stability, nominal calibration factor (for relative method) and absolute dose calibration of machine. Keeping these parameters in mind, the estimated relative percentage uncertainty associated with the absolute point dose measurement is 2.1% (k=1). On the other hand, the relative percentage uncertainty associated with the relative point dose verification method is estimated to 1.0% (k=1). To compare both point dose measurement methods, 13 head and neck (H&N) IMRT patients were selected. A point dose for each patient was measured with both methods. The average percentage difference between TPS computed dose and measured absolute relative point dose was 1.4% and 1% respectively. The results of this comparative study show that while choosing the relative or absolute point dose measurement technique, both techniques can produce similar results for H&N IMRT treatment plans. There is no statistically significant difference between both point dose verification methods based upon the t-test for comparing two means.

삼직교 열선유속계의 간편한 측정법 개발 (Development of Easy Measurement Method of Orthogonal Triple-Sensor Hot-Wire Anemometer)

  • 김진권;강신형
    • 대한기계학회논문집B
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    • 제24권1호
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    • pp.85-92
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    • 2000
  • Easy measurement method of orthogonal triple-sensor hot-wire anemometer is developed. Advantages of the new method is that it does not require either the exact orthogonality of the installed wires which cannot be kept during the probe manufacture and repair, nor the knowledge of the wire installation angles and the yaw and pitch coefficient of the wires. The new method introduced yaw and pitch calibration coefficients which are designed to increase monotonically with yaw and pitch angles. So the resulting calibration network is simple to recognize compared with that of the previously suggested calibration method. Verification experiments showed good accuracy and independency of the directional calibration on velocity.

NGIS자료와 연계한 수질모의 결과의 자동보정 (Auto Calibration of Water Quality Modeling Using NGIS)

  • 한건연;이창희;김강모
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2004년도 학술발표회
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    • pp.1400-1403
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    • 2004
  • The current industrial development and the Increase of population along Nakdong River have produced a rapid Increase of wastewater discharge. This has resulted in problem of water quality control and management. Although many efforts have been carried out, water quality has not significantly improved. The goal of this study is to design a NGIS-based water quality management system for the scientific water quality control and management in the Nakdong River. For general water quality analysis, QULA2E model was applied to the Nakdong River. A sensitivity analysis was made to determine significant parameters and an optimization was made to estimate optimal values. The calibration and verification were performed by using observed water quality data for Nakdong River. A water qualify management system for Nakdong River was made by connecting the QUAL2E model to ArcView. It allows a Windows-based Graphic User Interface(GUI) to implement all operation with regard to water quality analysis. The modeling system in this study will be an efficient NGIS for planning of water quality management.

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