• Title/Summary/Keyword: CTR

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The Relationship of Pulmonary Artery Copper Concentrations and Genes Involved in Copper Homeostasis in Cattle, Swine, and Goats

  • Han, Hyung-Chul;So, Hye-Jin;Domby, Elizabeth;Engle, Terry
    • Asian-Australasian Journal of Animal Sciences
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    • v.25 no.2
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    • pp.194-199
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    • 2012
  • Liver and pulmonary artery tissue from 5 Angus cross bred steers, 6 goats, and 6 pigs were collected at a commercial abattoir to examine the relationship of pulmonary artery copper (Cu) concentrations and genes involved in copper homeostasis. Liver and pulmonary artery samples were collected at the time of harvest and snap frozen. Liver and pulmonary artery Cu concentrations were determined via flame atomic absorption spectrophotometry and gene expression was determined via real time PCR. Liver Cu concentrations (mg Cu/kg DM${\pm}$SE) were higher (p<0.01) in cows ($396.4{\pm}109.1$) and goats ($181.4{\pm}37.0$) than in pigs ($19.2{\pm}3.5$). All liver Cu concentrations were within normal ranges and considered adequate for each species. Liver Cu concentration was more variable in cows and goats compared to pig liver Cu concentrations. Pulmonary artery ${\beta}$-hydroxylproline was higher (p<0.01) in cow and pig than goat. Real Time PCR revealed that goat liver atp7a was positively correlated ($r^2$ = 0.92; p<0.01) to liver Cu concentrations while cow and pig atp7a was not correlated to liver Cu concentration. In the pig, liver atp7a concentration was positively correlated to atp7b ($r^2$ = 0.66; p<0.05). Pulmonary artery Cu concentration was highest in cows ($14.9{\pm}4.7$), intermediate in pigs ($8.9{\pm}3.3$), and lowest in goats ($3.9{\pm}1.1$). Goat pulmonary artery Cu concentration was not correlated to ctr1 concentration, however, atp7a concentration was positively correlated with ctr1 ($r^2$ = 0.90; p<0.01). In cow pulmonary artery, loxl1 concentration was positively correlated to eln mRNA concentration ($r^2$ = 0.91; p<0.02). Pulmonary artery CTR1 protein concentration was positively correlated to pulmonary artery Cu ($r^2$ = 0.85; p = 0.03) concentration while negatively correlated to liver Cu ($r^2$ = -0.79; p<0.04). Pulmonary artery Cu concentration was not correlated to concentration of Cu homeostatic genes in the pig. These data indicate that genes involved in Cu homeostasis (ctr1, atp7A, atp7B, loxl1 and eln) are differently regulated in different species.

A Study on Antigencity (Immunotoxicity Study) to the Expressed Proteins of ${\beta}$-Carotene Biofortified Rice (베타카로틴강화미 발현단백질에 대한 항원성연구)

  • Park, Soo-Jin;Jeong, Mi-Hye;Chang, Hee-Seop;O, Jin-Cheol;Park, Kyung-Hun;Park, Jae-Yup
    • The Korean Journal of Pesticide Science
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    • v.15 no.3
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    • pp.289-297
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    • 2011
  • As part of safety evaluation of 2A (amono acid), PAT (phosphinotricin Acetyl-transferase), CtrI (Carotene desaturase) and PSY (phytoene synthase), the expressed proteins inserted to ${\beta}$-carotene Biofortified rice were tested for antigencity test. As a result, the group of administering high-concentration PAT, the expressed protein, showed a great content of total WBC; however, other expressed proteins did not show much difference. Against ASA (Active Systemic Anaphylaxis) test, the group of administering high-concentration PAT, the expressed protein, showed mild or medium degree of symptoms, but there was no dead entity. According to the result of the PCA (Passive Cutaneous Anaphylaxis test), the group of administering high-concentration PAT, 2A, PSY, and mixture of expressed proteins indicated positive response in low anti-serum concentration, and the group of administering the clinical concentration of mixture indicated mild positive response. However, because the group of administering the clinical concentration of expressed proteins, PAT, 2A, PSY, and CtrI, did not show positive response, it is thought that IgE is not generated. Further studies are needed to verify the safety of ${\beta}$-carotene Biofortified rice.

Assessment of Entrance Surface Dose and Image Distortion in Accordance with Abdominal Obesity in the Chest Radiography (흉부 X-선 검사에서 복부비만에 따른 입사표면선량과 영상 왜곡도 평가)

  • Kim, Boo Soon;Park, Jeong Kyu;Kwon, Soon Mu
    • Journal of the Korean Society of Radiology
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    • v.9 no.7
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    • pp.473-478
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    • 2015
  • Abdominal obesity is one of the most influential index to predict of insulin resistance syndrome/metabolic syndrome in social demographic characteristics. It is matter of fact that radiation dose are increasing with development of medical treatment and device. In this study, we estimated distortion between reference image and entrance surface dose when take a chest radiography forward chest phantom assumed abdominal obesity. When angle of chest phantom incline $5^{\circ}$ forward, thoracic transverse and longitudinal diameter increase 1.22% and 0.44% each. Also cardiac transverse diameter increase 1.01% and cardio-throracic ratio (CTR) decrease 0.27% in the same situation of incline to $5^{\circ}$ forward. Thoracic transverse diameter shows the largest increase, and CTR was decreased. But entrance surface dose to phantom increase significantly 6.12% when angle of chest phantom incline $5^{\circ}$ forward. In conclusion, we have to pay attention to accurate positioning, to prevent a distortion of image through incline, and make patients not to expose to additional radiation.

Optimized Implementation of PIPO Lightweight Block Cipher on 32-bit RISC-V Processor (32-bit RISC-V상에서의 PIPO 경량 블록암호 최적화 구현)

  • Eum, Si Woo;Jang, Kyung Bae;Song, Gyeong Ju;Lee, Min Woo;Seo, Hwa Jeong
    • KIPS Transactions on Computer and Communication Systems
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    • v.11 no.6
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    • pp.167-174
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    • 2022
  • PIPO lightweight block ciphers were announced in ICISC'20. In this paper, a single-block optimization implementation and parallel optimization implementation of PIPO lightweight block cipher ECB, CBC, and CTR operation modes are performed on a 32-bit RISC-V processor. A single block implementation proposes an efficient 8-bit unit of Rlayer function implementation on a 32-bit register. In a parallel implementation, internal alignment of registers for parallel implementation is performed, and a method for four different blocks to perform Rlayer function operations on one register is described. In addition, since it is difficult to apply the parallel implementation technique to the encryption process in the parallel implementation of the CBC operation mode, it is proposed to apply the parallel implementation technique in the decryption process. In parallel implementation of the CTR operation mode, an extended initialization vector is used to propose a register internal alignment omission technique. This paper shows that the parallel implementation technique is applicable to several block cipher operation modes. As a result, it is confirmed that the performance improvement is 1.7 times in a single-block implementation and 1.89 times in a parallel implementation compared to the performance of the existing research implementation that includes the key schedule process in the ECB operation mode.

Ignition resistance of CaO added Mg-3Al, Mg-6Al and Mg-9Al Eco-Mg alloys (CaO가 첨가된 Mg-3Al, Mg-6Al 및 Mg-9Al Eco-Mg 합금의 발화 저항성 평가)

  • Lee, Jin-Kyu;Kim, Shae-K.
    • Journal of Korea Foundry Society
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    • v.31 no.2
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    • pp.60-65
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    • 2011
  • Molten magnesium alloys and magnesium products are easily oxidized and burned when they are exposed to high temperature for manufacturing process and by accident. In order to solve these problems, CaO addition in magnesium alloys has been developed. The ignition resistance of CaO added Mg-3Al, Mg-6Al, and Mg-9Al Eco-Mg alloys were investigated in comparison with those of magnesium alloys without CaO. The ignition resistance was examined by three methods : DTA, furnace chip ignition test, and torch ignition test. DTA was carried out for obtaining quantitative ignition temperature data with respect to specimen geometry and test environment; the furnace ignition test for burr and chip ignition temperature data; and the torch test for ignition temperature data for manufactured products. The ignition resistance of magnesium alloys under all conditions greatly increased by CaO addition.

FPGA Implementation of ARIA Encryption/Decrytion Core Supporting Four Modes of Operation (4가지 운영모드를 지원하는 ARIA 암호/복호 코어의 FPGA 구현)

  • Kim, Dong-Hyeon;Shin, Kyung-Wook
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2012.10a
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    • pp.237-240
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    • 2012
  • This paper describes an implementation of ARIA crypto algorithm which is a KS (Korea Standards) block cipher algorithm. The ARIA crypto-core supports three master key lengths of 128/192/256-bit specified in the standard and the four modes of operation including ECB, CBC, CTR and OFB. To reduce hardware complexity, a hardware sharing is employed, which shares round function in encryption/decryption module with key initialization module. The ARIA crypto-core is verified by FPGA implementation, the estimated throughput is about 1.07 Gbps at 167 MHz.

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Phase transition properties of tungsten contained vanadium oxides film (텅스텐 첨가에 따른 바나듐 막의 상전이 특성 변화에 대한 연구)

  • Choi, Jong-Bum;Jo, Jung-Ho;Lee, Yong-Hyun;Choi, Byung-Yul;Lee, Moon-Seok;Kim, Byung-Ik;Shin, Dong-Wook
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2005.11a
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    • pp.208-209
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    • 2005
  • 바나듐 산화물은 반도성-금속성으로 상전이 하는 CTR특성의 대표적인 산화물로 상전이 온도인 68$^{\circ}C$에서 저항의 급변 특성을 보인다. 여기에 Fe, Ni, Mo, Ti, W과 같은 금속성 산화물을 첨가함에 따라 상전이온도를 움직일 수 있다. 그중 $WO_3$를 첨가함으로써 상전이온도를 상온까지 낮출 수 있다. Inorgnic sol-gel 법에 의해 바나듐-텅스텐 sol을 제조 하였으며, 제조된 sol을 기판에 코팅한 후 환원분위기에서 열처리 하여 막을 얻었다. 온도-저항 특성 측정 결과 순수 바나듐 막은 상전이 온도는 68$^{\circ}C$ 전기저항 감소폭은 $10^4$order 이였으나 바나듐-텅스텐막의 상전이 온도는 38$^{\circ}C$, 전기저항 감소폭은 $10_{15}$order 로 감소함을 확인 하였다.

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Development Trend of Damping Mg Alloys (진동 감쇠능 마그네슘 합금의 개발 동향)

  • Jang, Dong-In;Kim, Shae-K.
    • Journal of Korea Foundry Society
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    • v.28 no.5
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    • pp.199-203
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    • 2008
  • 현재 사용되고 있는 진동감쇠능 Mg-Zr 합금인 K1A는 우수한 진동감쇠능을 갖으나 열악한 기계적 특성과 Zr이 고가이면서 고융점 원소로 합금화가 어렵다는 문제점 때문에 진동테이블, 미사일 유도시스템 및 레코딩 장비 등에 소량만 적용되고 있다. Mg-Ni 합금의 경우Ni가 Mg 용탕 내에 고용되지 않아 우수한 진동감쇠능을 갖으나 Fe, Cu등과 함께 Mg의 부식을 가속시키는 원소로 사용이 제한적일 뿐 아니라 Zr과 마찬가지로 Ni도 고융점 원소로 합금화가 어렵다는 것도 문제점으로 작용하고 있다. Mg-Si 합금의 경우 Si이 극소량만 고용되어 우수한 진동감쇠능을 보이며 Ni과 달리 부식에 영향을 받지 않는 원소이지만 Zr, Ni와 마찬가지로 고가이면서 고융점 원소로 합금화가 어렵다는 문제점이 있다. Mg 용탕에 첨가하게 되면 용탕의 표면에 MgO, CaO 피막을 형성하여 발화현상을 억제할 뿐 아리라 첨가량의 증가에 따라 발화온도를 상승시키는 Ca의 경우 Mg 내에 고용되어 진동감쇠능을 감소시킬 뿐 아니라 유동성 저하 및 열간균열을 야기하는 것으로 나타났다. 그러나 CaO의 경우 Mg내에 고용되지 않고, 가격이 저렴하며 Mg 고유 특성의 변화가 적다. 또한 Ca와 같이 Mg 용탕의 발화를 억제하여 보호가스인 $SF_6$를 사용하지 않아도 된다. 이런 다양한 장점을 갖는 CaO를 첨가한 Mg합금이 진동감쇠능을 유지하면서 기계적 특성이 향상된다면 주행 시 안전성 및 정음성이 요구되는 수송기기 분야와 외부충격으로부터 데이터 보호가 필수적인 휴대용 전자정보통신기기 분야에서 적용이 증가할 전망이며 이에 따라 이 분야에 대한 지속적인 연구와 투자가 이루어져야 할 것이다.