• Title/Summary/Keyword: CT Coefficient

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Clinical Correlation between the Autoimmune Thyroid Disease for the Thyroid Autoimmune Antibodies and the Maximum Standardized Uptake Value: Base on the Hashimoto's Thyroiditis and the Graves' Disease (자가 면역 갑상선 질환에 대한 최대 표준섭취계수와 갑상선 자가 항체의 임상적 상관관계: 하시모토 갑상선염과 그레이브스병 중심으로)

  • Woo, Minsun;Baek, Chulin;Yoo, Jueun;Song, Jongwoo;Im, Inchul;Son, Juchul;Cho, Soodong;Lee, Jaeseung
    • Journal of the Korean Society of Radiology
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    • v.8 no.5
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    • pp.241-248
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    • 2014
  • The purpose of this study were to analyze the clinical correlation between the thyroid autoimmune antibodies (anti-TPO Ab, anti-TG Ab, and TSH) and the maximum standardized uptake value ($SUV_{max}$) base on the Hashimoto's thyroiditis and the Graves' disease in diffusely $^{18}F-FDG$ uptake of the thyroid gland to the PET/CT image. To achieve this, we was performed the PET/CT examination for the 1,097 subjects from May 2010 to April 2013 in the health screening, and was detected the diffused FDG thyroid uptake, and was additionally performed the thyroid function test (TFT) and the ultrasound (US). As a results, the autoimmune thyroid disease with the diffused FDG thyroid uptake were discovered 39 patients (3.9%), of this, the Hashimoto's thyroiditis was 43.6% and the Graves' disease was 23.1%. Hashimoto's thyroiditis was shown the positive reaction of high titer between the anti-TPO Ab and the anti-TG Ab level, and the correlation coefficient between the $SUV_{max}$ and the anti-TPO Ab was a statistically significant (r>04, p<0.05). Also, Graves' disease was shown the positive reaction of high titer most of the thyroid autoimmune antibodies, and the correlation coefficient between the $SUV_{max}$ and the anti-TPO Ab was a statistically significant (r>05, p<0.01). Therefor, when have a high standard of the $SUV_{max}$ due to the diffusely $^{18}F-FDG$ uptake of the thyroid gland, Hashimoto's thyroiditis and Graves' disease were proportionally increased the anti-TPO Ab and TSH level, respectively. The correlation coefficient between the $SUV_{max}$ and the thyroid autoimmune antibodies will be the most influential criterion that was a standard of judgment for the epihpenomenon of the autoimmune thyroid disease, and it will be available for the clinical application.

A Statistical Analysis of Fatigue Crack Growth under Constant-Amplitude Loads (일정진폭하중하의 피로균열전파의 통계적 특성)

  • Jeong, Hyeon-Cheol;Lim, Young-Kyu;Kim, Seon-Jin
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2002.05a
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    • pp.104-109
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    • 2002
  • In this paper, a statistical analysis of fatigue crack growth behavior under constant amplitude loads has been carried out. Fatigue crack growth tests were conducted on sixteen pre-cracked compact tension (CT) specimens of the pressure vessel (SPV50) steel in controlled identical load and environmental conditions. The assessment of the statistical distribution of fatigue crack growth experimental data obtained from SPV50 steel was studied and also the correlation of the parameter C and m in the Paris-Erdogan law was discussed. The probability distribution function of fatigue crack growth life seems to follow the 3-parameter Weibull. The fatigue crack growth rate seems to follow the 3-parameter Weibull and the log-normal distribution. The coefficient of variation (COV) of fatigue crack growth life was observed to decrease as the crack grows. A strong negative linear correlation exists between the coefficient C and the exponent m in Paris model. Fatigue crack growth rate data shows a normal distribution for both m and logC.

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Probabilistic Fatigue Crack Growth Behavior under Constant Amplitude Loads (일정진폭하중하의 확률론적 피로균열전파거동)

  • Jeong, Hyeon-Cheol;Kim, Seon-Jin
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.27 no.6
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    • pp.923-929
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    • 2003
  • In this paper, an analysis of fatigue crack growth behavior from a statistical point of view has been carried out. Fatigue crack growth tests were conducted on sixteen pre-cracked compact tension (CT) specimens of the pressure vessel (SPV50) steel in controlled identical load and environmental conditions. The assessment of the statistical distribution of fatigue crack growth experimental data obtained from SPV50 steel was studied and also the correlation of the parameter C and m in the Paris-Erdogan law was discussed. The probability distribution function of fatigue crack growth life seems to follow the 3-parameter Weibull. The fatigue crack growth rate seems to follow the 3-parameter Weibull and the log-normal distribution. The coefficient of variation (COV) of fatigue crack growth life was observed to decrease as the crack grows. Fatigue crack growth rate data shows a normal distribution for both m and logC. A strong negative linear correlation exists between the coefficient C and the exponent m.

Definition of Tumor Volume Based on 18F-Fludeoxyglucose Positron Emission Tomography in Radiation Therapy for Liver Metastases: An Relational Analysis Study between Image Parameters and Image Segmentation Methods (간 전이 암 환자의 18F-FDG PET 기반 종양 영역 정의: 영상 인자와 자동 영상 분할 기법 간의 관계분석)

  • Kim, Heejin;Park, Seungwoo;Jung, Haijo;Kim, Mi-Sook;Yoo, Hyung Jun;Ji, Young Hoon;Yi, Chul-Young;Kim, Kum Bae
    • Progress in Medical Physics
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    • v.24 no.2
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    • pp.99-107
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    • 2013
  • The surgical resection was occurred mainly in liver metastasis before the development of radiation therapy techniques. Recently, Radiation therapy is increased gradually due to the development of radiation dose delivery techniques. 18F-FDG PET image showed better sensitivity and specificity in liver metastasis detection. This image modality is important in the radiation treatment with planning CT for tumor delineation. In this study, we applied automatic image segmentation methods on PET image of liver metastasis and examined the impact of image factors on these methods. We selected the patients who were received the radiation therapy and 18F-FDG PET/CT in Korea Cancer Center Hospital from 2009 to 2012. Then, three kinds of image segmentation methods had been applied; The relative threshold method, the Gradient method and the region growing method. Based on these results, we performed statistical analysis in two directions. 1. comparison of GTV and image segmentation results. 2. performance of regression analysis for relation between image factor affecting image segmentation techniques. The mean volume of GTV was $60.9{\pm}65.9$ cc and the $GTV_{40%}$ was $22.43{\pm}35.27$ cc, and the $GTV_{50%}$ was $10.11{\pm}17.92$ cc, the $GTV_{RG}$ was $32.89{\pm}36.8$4 cc, the $GTV_{GD}$ was $30.34{\pm}35.77$ cc, respectively. The most similar segmentation method with the GTV result was the region growing method. For the quantitative analysis of the image factors which influenced on the region growing method, we used the standardized coefficient ${\beta}$, factors affecting the region growing method show GTV, $TumorSUV_{MAX/MIN}$, $SUV_{max}$, TBR in order. The result of the region growing (automatic segmentation) method showed the most similar result with the CT based GTV and the region growing method was affected by image factors. If we define the tumor volume by the auto image segmentation method which reflect the PET image parameters, more accurate and consistent tumor contouring can be done. And we can irradiate the optimized radiation dose to the cancer, ultimately.

Analysis of Tissue Equivalent Characteristics of Agar Phantom for Hyperthermia Therapy (온열종양치료 한천 팬텀의 조직등가 특성 분석)

  • Jeong-Geun Park;Kyeong-Hwan Jeong;Jeong-Min Seo
    • Journal of the Korean Society of Radiology
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    • v.17 no.6
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    • pp.985-991
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    • 2023
  • A tissue-equivalent phantom is necessary for quality control of hyperthermia therapy. However, since there is no phantom for this purpose, phantoms made from agar are being used in various studies. The tissue-equivalent properties of the agar phantom were confirmed by comparison with the tissue-equivalent material bolus in this study. CT images of the agar phantom and bolus were acquired, and tissue equivalent characteristics were analyzed with image analysis and dose calculation using a computerized radiation therapy planning system. The average pixel value was 96.960±10.999 in bolus, 108.559±8.233 in 3% agar phantom, and 111.844±8.651 in 4% agar phantom. Using the SSD technique, 100 cGy was prescribed at a depth of 1.5 cm and 6 MV X -ray was set to irradiated to 10x10 cm2, and the absorbed dose according to depth was calculated from the central axis of the beam. The intraclass correlation coefficient of dose distribution of bolus, 3% agar phantom, and 4% agar phantom was 0.979 (p<.001, 95%CI .957-.991). The density (g/cm3) at the point where the absorbed dose was calculated was 0.990±0.020 at the bolus, 1.018±0.020 at the 3% agar phantom, and 1.035±0.024 at the 4% agar phantom. In this study, the internal density distribution and uniformity of the agar phantom were confirmed to be appropriate as a tissue equivalent material by analysis of CT images and a computerized radiation therapy planning system.

Effect of Stem Design on Contact Pressure and Stress Distribution of End-of-stem in Revision TKR (슬관절 재전치환술용 경골 삽입물 형상이 주대 말단부의 접촉압력과 응력 분포에 미치는 영향)

  • Kim, Yoon-Hyuk;Kwon, Oh-Soo;Park, Si-Mon
    • Journal of the Korean Society for Precision Engineering
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    • v.23 no.11 s.188
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    • pp.126-134
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    • 2006
  • In this study, the effect of stem-end design on contact pressure and stress distribution in revision TKR was investigated using finite element method. The finite element model of tibia, including the cortical bone, the cancellous bone and canal, was developed based on CT images. The implant models with various stem lengths, diameters, friction coefficients, and press-fit effects were considered. The results showed that the longer stem length, the stronger press-fit, the bigger stem diameter, and the higher friction coefficient increased both peak contact pressure and Von-Mises stress distributions. The results supported the clinical hypothesis that peak contact pressure and stress are related to the stem end pain. The results of this study will be useful to design the stem and reduce the end-of-stem pain in revision TKR.

Power Consumption for Double-Stage Paddle Impeller in Cylindrical and Spherical Agitated Vessels (원통 및 구형교반조에서의 2단 Paddle 임펠러에 대한 소요동력)

  • Lee, Young-Sei;Choi, Hyun-Kuk;Shida, Hirotaka
    • Journal of the Korean Society of Industry Convergence
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    • v.9 no.4
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    • pp.247-253
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    • 2006
  • Power consumption for double-stage paddle impeller in spherical and cylindrical agitated vessel was measured over a wide range of Reynolds number from laminar to turbulent flow regions. The power correlation was obtained which was applied to both spherical and cylindrical vessel, when the apparent diameter of the spherical vessel was equal to the diameter of the cylindrical vessel which had a height equal to its diameter and had the same volume as the spherical vessel. The power consumption for the double-stage impeller was dependent upon the distance of among the impeller in the agitated vessels, as follows: $$f/2={\frac{C_L}{Re_G}}+{\frac{Ct}{2}}({\frac{C_tr}{Re_g}}+Re_g)^{-m}$$

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Medical Image Compression using Adaptive Subband Threshold

  • Vidhya, K
    • Journal of Electrical Engineering and Technology
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    • v.11 no.2
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    • pp.499-507
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    • 2016
  • Medical imaging techniques such as Magnetic Resonance Imaging (MRI), Computed Tomography (CT) and Ultrasound (US) produce a large amount of digital medical images. Hence, compression of digital images becomes essential and is very much desired in medical applications to solve both storage and transmission problems. But at the same time, an efficient image compression scheme that reduces the size of medical images without sacrificing diagnostic information is required. This paper proposes a novel threshold-based medical image compression algorithm to reduce the size of the medical image without degradation in the diagnostic information. This algorithm discusses a novel type of thresholding to maximize Compression Ratio (CR) without sacrificing diagnostic information. The compression algorithm is designed to get image with high optimum compression efficiency and also with high fidelity, especially for Peak Signal to Noise Ratio (PSNR) greater than or equal to 36 dB. This value of PSNR is chosen because it has been suggested by previous researchers that medical images, if have PSNR from 30 dB to 50 dB, will retain diagnostic information. The compression algorithm utilizes one-level wavelet decomposition with threshold-based coefficient selection.

Magnetic Properties of Fe3-x MnxO4 Thin Films by FMR

  • Kim, Ki-Hyeon;Kim, Young-Ho;Ha, Tae-Wook;Lee, Jeong-Sik;Park, Mann-Jang
    • Journal of Magnetics
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    • v.2 no.2
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    • pp.38-41
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    • 1997
  • Spinel ferrite thin films Fe3-x MnxO4 (x=0.000, 0.006, 0.0010, 0.015, 0.023) were prepared on the coverglass by ferrite plating technique. To investigate the uniaxial anisotrpy of the samples, the saturation and effective magnetization of the thin films were measured by VSM(vibrating sample magnetometer) and FMR(ferromagnetic resonance) measurements respectively. The spectroscopic splitting g factor were estimated from the ferromagnetic resonance curves. For x=0.000, 0.006, the effective magnetization was measured of temperatures form T=77 K to T=300 K. The results were analyzed in terms of Bloch's law Ms(T) = Ms(0) (1-BT3/2-CT5/2). The Bloch coefficient B, C were determined by fitting. Ms(0) was obtained by extrapolating Meff to 0 K. From this result, the spin wave stiffness constants D was also determined.

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Evaluation of the Effect of using Fractal Feature on Machine learning based Pancreatic Tumor Classification (기계학습 기반 췌장 종양 분류에서 프랙탈 특징의 유효성 평가)

  • Oh, Seok;Kim, Young Jae;Kim, Kwang Gi
    • Journal of Korea Multimedia Society
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    • v.24 no.12
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    • pp.1614-1623
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    • 2021
  • In this paper, the purpose is evaluation of the effect of using fractal feature in machine learning based pancreatic tumor classification. We used the data that Pancreas CT series 469 case including 1995 slice of benign and 1772 slice of malignant. Feature selection is implemented from 109 feature to 7 feature by Lasso regularization. In Fractal feature, fractal dimension is obtained by box-counting method, and hurst coefficient is calculated range data of pixel value in ROI. As a result, there were significant differences in both benign and malignancies tumor. Additionally, we compared the classification performance between model without fractal feature and model with fractal feature by using support vector machine. The train model with fractal feature showed statistically significant performance in comparison with train model without fractal feature.