• Composites Research
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• v.25 no.4
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• pp.117-125
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• 2012

Warpage of the film insert molded (FIM) part is caused by an asymmetric residual stress distribution. Asymmetric residual stress and temperature distribution is generated by the retarded heat transfer in the perpendicular direction to the attached film surface. Since warpage was not prevented by controlling injection molding conditions, glass fiber (GF) filled composites were employed as substrates for film insert molding to minimize the warpage. Distribution of short GFs was evaluated by using micro-CT equipment. Proper models for micro mechanics, anisotropic thermal expansion coefficients, and closure approximation should be selected in order to calculate fiber orientation tensor and warpage of the FIM part with the composite substrate. After six kinds of micro mechanics models, three models of the thermal expansion coefficient and five models of the closure approximation had been considered, the Mori-Tanaka model, the Rosen and Hashin model, and the third orthotropic closure approximation were selected in this study. The numerically predicted results on fiber orientation tensor and warpage were in good agreement with experimental results and effects of GF reinforcement on warpage of the FIM composite specimen were identified by the numerical results.

• The Journal of the Korea Contents Association
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• v.9 no.6
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• pp.266-274
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• 2009

An abdominal aortic aneurysm occurs most commonly in older individuals (between 65 and 75), and more in men and smokers. The most important complication of an abdominal aortic aneurysm is rupture, which is most often a fatal event. An abdominal aortic aneurysm weakens the walls of the blood vessel, leaving it vulnerable to bursting open, or rupturing, and spilling large amounts of blood into the abdominal cavity. surface modeling is very useful to surgery for quantitative analysis of abdominal aortic aneurysm. the 3D representation and surface modeling an abdominal aortic aneurysm structure taken from Multi Detector Computed Tomography. The construction of the 3D model is generally carried out by staking the contours obtained from 2D segmentation of each CT slice, so the quality of the 3D model strongly defends on the precision of segmentation process. In this work we present deformable model algorithm. deformable model is an energy-minimizing spline guided by external constraint force. External force which we call Gradient Vector Flow, is computed as a diffusion of a gradient vectors of gray level or binary edge map derived from the image. Finally, we have used snakes successfully for abdominal aortic aneurysm segmentation the performance of snake was visually and quantitatively validated by experts.

• Journal of the Korea Computer Graphics Society
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• v.29 no.5
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• pp.21-30
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• 2023

Accurate segmentation of the kidney tumor is necessary to identify shape, location and safety margin of tumor in abdominal CT images for surgical planning before renal partial nephrectomy. However, kidney tumor segmentation is challenging task due to the various sizes and locations of the tumor for each patient and signal intensity similarity to surrounding organs such as intestine and spleen. In this paper, we propose a semi-supervised learning-based mean teacher network that utilizes both labeled and unlabeled data using a kidney local guided map including kidney local information to segment small-sized kidney tumors occurring at various locations in the kidney, and analyze the performance according to the kidney tumor size. As a result of the study, the proposed method showed an F1-score of 75.24% by considering local information of the kidney using a kidney local guide map to locate the tumor existing around the kidney. In particular, under-segmentation of small-sized tumors which are difficult to segment was improved, and showed a 13.9%p higher F1-score even though it used a smaller amount of labeled data than nnU-Net.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.13 no.10
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• pp.2163-2170
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• 2009

We present an automated, energy minimized-based method for Lung parenchyma segmenting Chest Computed Tomography(CT) datasets. Deformable model is used for energy minimized segmentation. Quantitative knowledge including expected volume, shape of Chest CT provides more feature constrain to diagnosis or surgery operation planning. Segmentation subdivides an lung image into its consistent regions or objects. Depends on energy-minimizing, the level detail image of subdivision is carried. Segmentation should stop when the objects or region of interest in an application have been detected. The deformable model that has attracted the most attention to date is popularly known as snakes. Snakes or deformable contour models represent a special case of the general multidimensional deformable model theory. This is used extensively in computer vision and image processing applications, particularly to locate object boundaries, in the mean time a new type of external force for deformable models, called gradient vector flow(GVF) was introduced by Xu. Our proposed algorithm of deformable model is new external energy of GVF for exact segmentation. In this paper, Clinical material for experiments shows better results of proposal algorithm in Lung parenchyma segmentation on Chest CT.

• Tuberculosis and Respiratory Diseases
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• v.67 no.5
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• pp.436-444
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• 2009

Background: Micro computed tomography (CT) is rapidly developing as an imaging tool, especially for mice, which have become the experimental animal of choice for many pulmonary disease studies. We evaluated the usefulness of micro CT for evaluating lung fibrosis in the murine model of bleomycin-induced lung inflammation and fibrosis. Methods: The control mice (n=10) were treated with saline. The murine model of lung fibrosis (n=60) was established by administering bleomycin intra-tracheally. Among the 70 mice, only 20 mice had successful imaging analyses. We analyzed the micro CT and pathological findings and examined the correlation between imaging scoring in micro CT and histological scoring of pulmonary inflammation or fibrosis. Results: The control group showed normal findings on micro CT. The abnormal findings on micro CT performed at 3 weeks after the administration of bleomycin were ground-glass opacity (GGO) and consolidation. At 6 weeks after bleomycin administration, micro CT showed various patterns such as GGO, consolidation, bronchiectasis, small nodules, and reticular opacity. GGO (r=0.84) and consolidation (r=0.69) on micro CT were significantly correlated with histological scoring that reflected pulmonary inflammation (p<0.05). In addition, bronchiectasis (r=0.63) and reticular opacity (r=0.83) on micro CT shown at 6 weeks after bleomycin administration correlated with histological scoring that reflected lung fibrosis (p<0.05). Conclusion: These results suggest that micro CT findings from a murine model of bleomycin-induced lung fibrosis reflect pathologic findings, and micro CT may be useful for predicting bleomycin-induced lung inflammation and fibrosis in mice.

• Journal of Korea Society of Industrial Information Systems
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• v.20 no.3
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• pp.81-86
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• 2015

We fabricated a 3D knee joint model through the imaging processing. The 3D shape information is different depends on specific conditions when the shape of real knee joint is extracted from CT/MRI sliced images. The two types of joint models were fabricated by using 3D printer in order to analysis of joint movement by slight difference of 3D shape information. The compressive force experiments were performed by using knee joint model. As the results, the compressive forces were changed with respect to the difference of geometry. Consequently, feasibility test should be performed before developing biomimetic bioreactor.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.4
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• pp.967-975
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• 2010

Image segmentation is one of the first steps leading to image analysis and interpretation, which is to distinguish objects from background. However, the active contour model can't exactly extract the desired objects because the phase only is 2. In this paper, we propose the method which can find the desired contours by composing the initial curve near the objects which have intensities of special range. The initial curve is calculated by the histogram equalization, the Gaussian equalization, and the threshold. The proposed method reduce the calculation speed and exactly detect the wanted objects because the initial curve set near by interested area. The proposed method also shows more efficient than the active contour model in the results applied the CT and MR images.

• Proceedings of the Materials Research Society of Korea Conference
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• 2009.05a
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• pp.44.1-44.1
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• 2009

최근 경조직 재생 (hard tissue regeneration) 에 대한 연구가 활발히 진행되고 있다. 그러나 이와같은 연구는 결손도입의 어려움 및 이차적인 골절의 위험성 때문에 대형동물을 중심으로 진행되고 있으며, 그 결과 동물실험에 있어서 시간적 경제적으로 큰 리스크를 수반한다. 그러나 유전자 변형동물의 대부분은 마우스이며, 분자생물학적 관점에서 골재생의 과정을 이해하기 위해서는 마우스를 이용한 골재생 모델의 확립이 필요하다. 따라서 본 연구에서는 마우스를 통해 경조직 재생모델의 제작방법을 검토함과 동시에, 골재생부위에 대한 골질 (bone quality) 및 골양 (bone quantity) 평가의 방법을 수립하는 것을 목적으로 하였다. 골결손은 생후 8주의 마우스에 시술하였다. 치과용 드릴을 이용하여 경골 (tibia) 길이의 30 % 부근의 내측(medial) 면에서 골수강 (marrow cavity) 방향으로 $500\;{\mu}m\varphi$의 원주형 결손을 도입하였다. 시술 후의 골재생과정을 관찰하기 위해 ${\mu}CT$ (SMX-100CT: Simazu) 를 이용하여 주기적으로 촬영하였으며, 골양 (BV/TV) 의 회복과정은3D-bon (RATOC) 을 이용하여 정량적인 해석을 수행하였다. 그리고 재생부의 골질 (아파타이트 배행성; BAp orientation) 평가는 투과형micro-beam XRD (R-AXIS BQ: Rigaku)를 이용하여 수행하였다.

• Journal of Chest Surgery
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• v.43 no.5
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• pp.506-512
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• 2010

Background: This study was designed to evaluate the FDG uptake ratio of mediastinal node and primary tumors using integrated PET/CT imaging combined with Glut-1 expression of the primary tumor in order to predict the N2 status more accurately in NSCLC patients. Material and Method: Patients who underwent integrated PET/CT scanning with a detectable mSUV for both primary tumors and mediastinal lymph nodes were eligible for this study. The FDG uptake ratio between the mediastinal node and the primary tumor was calculated. Result: The average mSUV of primary tumors and mediastinal nodes were, respectively, $7.4{\pm}2.2$ and $4.2{\pm}2.2$ in N2-positive patients and $7.6{\pm}3.7$ and $2.8{\pm}6.9$ in N2-negative patients. The mean FDG uptake ratio of mediastinal node to primary tumor were $0.58{\pm}0.23$ for malignant N2 lymph nodes and $0.45{\pm}0.20$ for benign lymph nodes (p<0.05). Models which combined Glut-1 expression with an FDG ratio have better diagnostic power than models that use the FDG uptake ratio alone. Conclusion: In some patients with a previous history of pulmonary tuberculosis or other inflammatory lung diseases, an FDG uptake ratio combined with Glut-1 expression may be useful in diagnosing mediastinal node metastasis more exactly.

• Imaging Science in Dentistry
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• v.34 no.1
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• pp.13-18
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• 2004

Purpose : This study was to evaluate the influence of slice thickness of computed tomography (CT) and rapid protyping (RP) type on the accuracy of 3-dimensional medical model. Materials and Methods: Transaxial CT data of human dry skull were taken from multi-detector spiral CT. Slice thickness were 1, 2, 3 and 4 mm respectively. Three-dimensional image model reconstruction using 3-D visualization medical software (V-works /sup TM/ 3.0) and RP model fabrications were followed. 2-RP models were 3D printing (Z402, Z Corp., Burlington, USA) and Stereolithographic Apparatus model. Linear measurements of anatomical landmarks on dry skull, 3-D image model, and 2-RP models were done and compared according to slice thickness and RP model type. Results: There were relative error percentage in absolute value of 0.97, 1.98,3.83 between linear measurements of dry skull and image models of 1, 2, 3 mm slice thickness respectively. There was relative error percentage in absolute value of 0.79 between linear measurements of dry skull and SLA model. There was relative error difference in absolute value of 2.52 between linear measurements of dry skull and 3D printing model. Conclusion: These results indicated that 3-dimensional image model of thin slice thickness and stereolithographic RP model showed relative high accuracy.