• The Journal of Korean Obstetrics and Gynecology
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• v.25 no.4
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• pp.1-11
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• 2012

Objectives: Osteoporosis, which occurs after menopause, is a kind of metabolic bone disorder. It develops when the bone mass begins to decrease radically, and its main symptoms are bone fracture and height-shortening. This thesis aims at what effects the Cuscutae Semen Extract(CSE) has on the prevention of osteoporosis in SD-rat that is caused by ovariectomy. Methods: The 24 female white rats, after removing their ovaries, were divided into the Normals, the Control group, and the CSE administrated group. For the next 8 weeks, distilled water to the normals and the control, and the CSE(45.9 mg/100 g) to the CSE administrated group were given in the mouths of them. After 8 weeks the rats were sacrificed. Weight, albumin, aspartate aminotransferase, alanine aminotransferase, total-cholesterol, triglyceride, phosphorus, calcium, tetraiodothyronine, estradiol, the weight of the femur, the amount of tibia ash, the area of trabecular bone, and the thickness of trabecular bone were measured. Results: The serum analysis shows that the calcium and phosphorous of the CSE administrated group significantly increased compared to that of the control group. Aspartate aminotransferase, alkalinephosphatase, total cholesterol, tetraiodothyronine of CSE group were decreased, but not so significant. Albumin, alanine aminotransferase, triglyceride and estradiol of the group showed the tendency to increase, but the significance wasn't admitted. Regarding the variation of bone, the femur weight and the ash content of tibia, CSE group was more increased than the control group but the significance wasn't admitted. The histological observation shows that the trabecular thickness was more increased than the control group, and trabecular area increased significantly compared to those of the control group. The number of osteoclast and osteoblast area of the CSE groups decreased significantly compared to those of the control group. Conclusions: From the result of the above study, CSE should be effective for the osteoporosis cure and precaution and deeper study through bedside and clinical demonstration is much needed from now on.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.4
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• pp.791-795
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• 2008

In the present study, Cordyceps sinensis extract (CSE) was evaluated to determine if it could protect pancreatic ${\beta}$ cells against cytokine-induced cytotoxicity of RINm5F cells. Treatment of cells with cytokines resulted in a decrease of viability, which was caused by increase of nitric oxide (NO) production. CSE protected cytokine-mediated viability reduction in a concentration-dependent manner. Incubation with CSE also induced a significant suppression of cytokine-induced inducible nitric oxide synthase (iNOS) protein and NO production. The molecular mechanism by which CSE inhibited iNOS protein expression appeared to involve the inhibition of $NF-{\kappa}B$ activation. The cytokine-stimulated RIN cells showed increases in $NF-{\kappa}B$ binding activity compared to unstimulated cells. However, pretreatment with CSE inhibited cytokines-induced $NF-{\kappa}B$ activation in RINm5F cells.

• Corrosion Science and Technology
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• v.16 no.5
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• pp.235-240
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• 2017

Regional cathodic protection has significant impact on pipeline integrity management. After risk analyses of a newly built gas distribution station constructed in an area with large dwelling density, risk score was high because of potential threat caused by galvanic corrosion. Except reinforced steel in concrete, there are four kinds of metal buried under earth: carbon steel, galvanized flat steel, zinc rod and graphite module. To protect buried pipeline from external corrosion, design and construction of regional cathodic protection was proposed. Current density was measured with potential using potential dynamic test and boundary element method (BEM) was used to calculate current requirement and optimize best anode placement during design. From our calculation on the potential, optimized conditions for this area were that an applied current was 3A and anode was placed at 40 meters deep from the soil surface. It results in potential range between $-1.128V_{CSE}$ and $-0.863V_{CSE}$, meeting the $-0.85V_{CSE}$ criterion and the $-1.2V_{CSE}$ criterion that no potential was more negative than $-1.2V_{CSE}$ to cause hydrogen evolution at defects in coating of the pipeline.

• KIPS Transactions on Computer and Communication Systems
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• v.4 no.1
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• pp.15-22
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• 2015

Estimating the number of distinct values is really well-known problems in network data measurement and many effective algorithms are suggested. Recent works have built upon technique called Linear Counting to solve the estimation problem for massive sets or spreaders in small memory. Sampling is used to reduce the measurement data, and it is assumed that sampling gives bad effect on the accuracy. In this paper, however, we show that the sampling on multi-set estimation sometimes gives better results for CSE with sampling than for MCSE that examines all the packets without sampling in terms of accuracy and estimation range. To prove this, we presented mathematical analysis, conducted experiment with real data, and compared the results of CSE, MCSE, and CSES.

• The Bulletin of The Korean Astronomical Society
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• v.44 no.1
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• pp.67.2-67.2
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• 2019

We present the results of KVN and ALMA observations toward WX Psc (IRC+10011) which is a long-period variable OH/IR star. The SiO masers of v=1 and v=2, J=5-4, and the SiO thermal emission of v=0, J=5-4 were observed together with H2O v2=1 (232.6 GHz) and continuum emission at ALMA Band 6 in October 2017 (Cycle 5). This observation aims to investigate the physical association between the inner and outer parts of the circumstellar envelope (CSE) swept by the stellar winds, which is very crucial to understand the asymmetric outward motions developed during the evolutionary phases from the asymptotic giant branch (AGB) stars to the planetary nebulae (PNe). The strong SiO maser features and thermal emissions are detected together with the continuum emission in ALMA observation, which imply the elongated morphology of the CSE of WX Psc. While the spatial resolution of about 20 mas in ALMA observation cannot clearly resolve the detailed characteristics of the inner part of the CSE, the Korean VLBI Network (KVN) observations show the spatial distributions of the v=1 J=1-0, J=2-1, J=3-2 SiO masers emitted from the inner regions of CSE, which are the complementary to the ALMA results. Therefore, we expect these results reveal how the bipolar features of the 22 GHz H2O maser are connected to the innermost region of CSE through the dust condensation region, which is closely related to the enormous mass ejection of the evolved stars.

• Proceedings of the Korean Information Science Society Conference
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• 2010.11a
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• pp.58-59
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• 2010

• Proceedings of the Acoustical Society of Korea Conference
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• autumn
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• pp.287-292
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• 2001

당과 같은 실내 음향 문제는 강당의 사용자와 관리자의 주관적인 평가가 배제되기 힘든 것이므로 문제를 개선하기 위해 물리적 측정이나 실험, 해석 등을 통한 다각적인 정량적 분석 자료를 산출하는 과정이 선행되어야 한다 이를 위해 본 논문에서는 기존의 강당에 대한 고유 음향 특성-잔향시간, 명료도, 음압레벨-을 실험과 컴퓨터 시뮬레이션을 통해 얻어 음향 분포를 파악하고, 현재 설치되어 있는 스피커의 지향성 및 위치 등에 따른 음향 특성을 알아보았다. 대표적인 음향평가 지수인 잔향 시간은 랜덤노이즈를 음원으로 사용하여 음향측정을 수행하였으며, 이 결과를 시뮬레이션과 비교함으로써 컴퓨터 시뮬레이션의 신뢰성 또한 검토하였다.

• Proceedings of the Korean Society of Computer Information Conference
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• 2015.07a
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• pp.5-8
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• 2015

소프트웨어의 작동 중에 중대한 고장 없이 유연하게 대처할 수 있는 성질은 견고성이라 불리며 임베디드 소프트웨어에서 중요하게 여겨진다. 본 논문에서는 개발 중인 임베디드 소프트웨어의 견고성을 조기에 검증하기 위하여, 실물 시스템을 이용한 테스트가 갖는 물리적 한계를 극복할 수 있는 Software-in-the-Loop 시뮬레이션을 이용하여 개발 중인 PC에 견고성 테스팅 환경을 갖추는 방법을 제시한다. 제시한 방법은 소프트웨어의 견고성을 표현할 수 있게끔 만드는 테스트 케이스를 생성하고, 가상 시뮬레이션 환경을 구성하여 테스트 케이스를 실행함으로써 소프트웨어의 견고성을 객관적인 수치의 형태로 나타내는 방법을 보인다.

• Proceedings of the Korea Information Processing Society Conference
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• 2012.11a
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• pp.1490-1492
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• 2012

프로파일링 도구는 프로그램 최적화뿐만 아니라 스케줄링이나 호출 그래프 작성, 프로그램의 부하 분석 등과 같은 많은 분야에서 이용되고 있다. 이 논문에서는 한국에서 많이 사용되는 운영체제인 윈도우즈 상에서 동작하며 실행 코드만으로 분석이 가능한 프로파일링 도구에 대해 알아본다. 특히 윈도우즈 상에서 동작하는 유명한 프로파일링 도구인 Very Sleepy, 리소스 모니터, PIX, CodeAnalyst, PCM의 특징에 대해 알아본다. 그리고 프로파일링 도구의 특징을 이용해 특정 상황에 적합한 프로파일링 도구를 제안한다.

• The Journal of Internal Korean Medicine
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• v.33 no.4
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• pp.520-532
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• 2012

Objectives : This study was carried out to investigate the effects of Coicis Semen Extract (CSE) on the experimental colitis induced by dextran sulfate sodium (DSS) in mice. Methods : Experimental colitis was induced by daily treatment with 5% DSS in the drinking water for 7 days in 6-week-old male ICR mice. The colitic mice were divided into three groups: the normal (N) group consisted of mice that were not inflammation-induced. The control (C) group was composed of untreated colitis elicited mice. The sample (S) group was administered CSE after colitis elicitation. The effects on colonic mucosal ulcers were evaluated by the morphological, histological and immunohistochemical change of the large intestine. Results : Inhibition of LPS-induced NO decreased in the S group. Inhibition of LPS-induced iNOS and COX-2 mRNA noticeably decreased in the S group from 0.25 mg/ml. In the common morphological and histochemical change, the erosion and the infiltration of inflammatory cells increased in the C group, while they noticeably decreased in the S group. The length of colon was shortened more in the C group than in the S group. The distributions of MUC2 and Hsp70 treated with CSE increased noticeably more in the S group than in the C group (p<0.05). It was confirmed histochemically and immunohistochemically that the distributions of iNOS, COX-2, MAC387, serotonin, apoptosis and PCNA treated with CSE decreased in the S group more than in the C group (p<0.05). Conclusions : It is confirmed that CSE has cytoprotective effect, so can alleviate inflammation process. Therefore, it is expected to have potential protective effect on colitis.