• Mass Spectrometry Letters
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• v.5 no.2
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• pp.57-61
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• 2014

A gravimetric standard addition method combined with internal standard calibration has been successfully developed for the accurate analysis of total arsenic in a laver candidate reference material. A model equation for the gravimetric standard addition approach using an internal standard was derived to determine arsenic content in samples. Handlings of samples, As standard and internal standard were carried out gravimetrically to avoid larger uncertainty and variability involved in the volumetric preparation. Germanium was selected as the internal standard because of its close mass to the arsenic to minimize mass-dependent bias in mass spectrometer. The ion signal ratios of $^{75}As^+$ to $^{72}Ge^+$ (or $^{73}Ge^+$) were measured in high resolution mode ($R{\geq}10,000$) to separate potential isobaric interferences by high resolution ICP/MS. For method validation, the developed method was applied to the analysis of arsenic content in the NMIJ 7402-a codfish certified reference material (CRM) and the result was $37.07mg{\cdot}kg^{-1}{\pm}0.45mg{\cdot}kg^{-1}$ which is in good agreement with the certified value, $36.7mg{\cdot}kg^{-1}{\pm}1.8mg{\cdot}kg^{-1}$. Finally, the certified value of the total arsenic in the candidate laver CRM was determined to be $47.15mg{\cdot}kg^{-1}{\pm}1.32mg{\cdot}kg^{-1}$ (k = 2.8 for 95% confidence level) which is an excellent result for arsenic measurement with only 2.8 % of relative expanded uncertainty.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.116-116
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• 2017

Low-temperature is one of the environmental stress factors that affect plant growth and development and consequently limit crop productivity. The control of seed germination under low-temperature is organized by many genes which are called quantitative trait loci (QTLs). High germination rate for low-temperature is an important factor of growing rice. Previously, we identified a major QTL controlling low-temperature germinability in rice using 96 introgression lines (ILs) derived from a cross between Oryza rufipogon (Rufi) and the Korean japonica cultivar, 'Hwaseongbyeo (HS)'. A $BC_3F_7$ line (TR5) showed better low-temperature germinability than its recurrent parent. TR5 was crossed with HS to develop a segregating F2:3 populations for the target QTL. Six SSR markers polymorphic between HS and Rufi were used to screen and fine map the qLTG1. The qLTG1 on chromosome 1, which accounted for 55.5% of the total phenotypic variation, confirmed that Rufi allele enhanced the low-temperature germinability. Intervals between markers CRM16 and CRM15, four candidate genes were identified. The identified candidate genes, which are encoded by a protein of unknown function, showed their direct involvement on seed germination at low-temperature. To identify genes targeted by qLTG1, we investigated the expression profiles of these candidate genes and germination behavior of qLTG1 under different stress conditions and compared to HS, Rufi, and TR5 at $13{\pm}2^{\circ}C$ for 3 days after incubation. Furthermore, transgenic rice plants will also be developed to conduct a detailed investigation on low-temperature germinability. Hence, the QTL for low-temperature germinability would be useful in rice breeding programs especially in the development of lines possessing low-temperature germinability.

• Analytical Science and Technology
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• v.16 no.3
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• pp.191-197
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• 2003

Two methods, IDMS (Isotope Dilution Mass Spectrometry) and controlled potential coulometry are compared by the determination of Pu for the NBL, CRM No.122, $PuO_2$. The recovery of Pu was found to be $1.002176{\pm}0.000452$ within the relative standard deviation of 0.045% (95% conf. level) although a small size of sample ($0.9{\mu}g$-Pu) was used in IDMS. The recovery using controlled potential coulometry were obtained in the range of 0.9923~0.9960. The analytical results of IDMS and controlled potential coulometry were good agreement within 0.6~1%. Base on these experiment results, The plutonium in HANARO irradiated fuel rod that separated portion of top, middle, and bottom were determined. The measured values of Pu are 1.155 mg, 2.483 mg and 1.920 mg in one gram of sample(fuel+clad), respectively.

• The Optical Journal
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• s.128
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• pp.25-27
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• 2010

디지털 인쇄는 다품종 소량 인쇄가 가능하고, 원하는 시기에 필요한 만큼만 출력할 수 있어 재고 및 폐기 처리가 줄어든다는 장점과 함께 내용 수정이 바로 가능하다는 점에서 옵셋 인쇄가 수행하지 못했던 만족시키면서 새로운 시장을 형성해 나가고 있다. "필요한 수량, 필요한 시간, 필요한 장소에 맞추어 인쇄한다"라는 POD(Print On Demand 주문형 인쇄) 컨셉에서 시작된 디지털인쇄는 CRM(고객관계관리) 기법의 실행 단계로서 1:1(One to One) DM, TransPromo(트랜스프로모) 등으로 점점 영역을 확장해 나가고 있다.

• Proceedings of the PSK Conference
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• 2000.04a
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• pp.98.1-98.1
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• 2000

• Journal of the Korean Society for Marine Environment & Energy
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• v.14 no.2
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• pp.107-113
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• 2011

To evaluate the performance of the hydrodynamic model, we introduced 10 skill assessments that are assorted by two groups: quantitative skill assessments (Absolute Average Error or AAE, Root Mean Squared Error or RMSE, Relative Absolute Average Error or RAAE, Percentage Model Error or PME) and qualitative skill assessments (Correlation Coefficient or CC, Reliability Index or RI, Index of Agreement or IA, Modeling Efficiency or MEF, Cost Function or CF, Coefficient of Residual Mass or CRM). These skill assessments were applied and calculated to evaluate the hydrodynamic modeling at one of Florida estuaries for water level, current, and salinity as comparing measured and simulated values. We found that AAE, RMSE, RAAE, CC, IA, MEF, CF, and CRM are suitable for the error assessment of water level and current, and AAE, RMSE, RAAE, PME, CC, RI, IA, CF, and CRM are good at the salinity error assessment. Quantitative and qualitative skill assessments showed the similar trend in terms of the classification for good and bad performance of model. Furthermore, this paper suggested the criteria of the "good" model performance for water level, current, and salinity. The criteria are RAAE < 10%, CC > 0.95, IA > 0.98, MEF > 0.93, CF < 0.21 for water level, RAAE < 20%, CC > 0.7, IA > 0.8, MEF > 0.5, CF < 0.5 for current, and RAAE < 10%, PME < 10%, CC > 0.9, RI < 1.15, CF < 0.1 for salinity.

• Journal of Technologic Dentistry
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• v.37 no.1
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• pp.9-15
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• 2015

Purpose: The purpose of this study was to compare the accuracy of the maxillary three-unit fixed dental prosthesis (FDPs) made using two CAD/CAM milling machines : DCM Group(Dentaim CAD/CAM milling machine), WCM Group(Wieland CAD/CAM milling machine). Methods: Each of 10 duplicate models was scanned by blue light scanner(Identica, Medit, Korea), and the three-unit FDPs (STL file) was designed using DelcamCAD. A total of 20 three-unit FDPs was fabricated, comprising 2 groups of 10 specimens each (shrinkage ratio is 1:1). The first three-unit FDPs STL file was used as a CAD reference model (CRM). Obtained STL files by scanning the inner surface of three-unit FDPs were convened into the point clouds-ASC II files. Discrepancies between the point clouds and CRM were measured by superimposition software. Statistical methods to analyze the data were used non-parametric method. The mean (SD) values were compared by a Mann-Whitney U-test. Type one error rate was set at 0.05. Results: WCM group had small discrepancies with $2.17{\mu}m$ of mean value compared to $4.44{\mu}m$ in DCM group. The accuracy values between the two groups showed a sratistically significant difference (Table 2, p<.05). Conclusion: The accuracy of the three-unit fixed dental prosthesis(FDPs) made of two CAD/CAM milling machines were statistically different. Accuracy with which the prosthesis made of WCM group was superior.

• Asia-Pacific Journal of Business
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• v.14 no.4
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• pp.289-303
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• 2023

Purpose - The purpose of this study is to investigate the types and forms of various marketing activities actually used in pharmaceutical companies and to empirically analyze the impact of these marketing activities on sales. Design/methodology/approach - This study categorize five years' worth of marketing activity data from a foreign pharmaceutical company 'A' which operates in South Korea into five categories. Multiple regression analysis and interaction effects are employed for data analysis. Findings - First, CRM calls, Detail calls, GP, and Web events have a positive impact on sales, but SoV does not show significant differences. Second, in the comparison between HQ1 and HQ2 based on patent ownership, Detail calls and Web events had a stronger impact on sales in HQ2, where the patent period is still in effect, compared to HQ1. However, SoV showed no difference between HQ1 and HQ2. Research implications or Originality - First, Detail Calls are more effective for drugs with active patents, while CRM Calls work better for drugs with expired patents. This emphasizes the need to customize call strategies based on patent status. Second, the significant impact of Web Events on sales in HQ2 compared to HQ1 suggests that online information access is crucial, indicating that customer receptivity varies based on product nature. Third, these insights, derived from data analysis, call for a shift in pharmaceutical marketing analysis methods away from traditional approaches. Finally, this study holds significance as one of the first empirical analyses using actual marketing data from pharmaceutical companies in South Korea.

• Korean Management Science Review
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• v.19 no.1
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• pp.189-196
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• 2002

Data clustering is often one of the first steps in data mining analysis. It Identifies groups of related objects that can be used as a starling point for exploring further relationships. This technique supports the development of population segmentation models, such as demographic-based customer segmentation. This paper Purpose to present the development of two phase hierarchical clustering algorithm for group formation. Applications of the algorithm for product-customer group formation in customer relationahip management are also discussed. As a result of computer simulations, suggested algorithm outperforms single link method and k-means clustering.

• Proceedings of the CALSEC Conference
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• 2004.02a
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• pp.251-254
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• 2004

1. Research Background ·Customer support or service in organization is one of the most important business improvement theme in improving their business competences. -Many customers view customer support as one of the most impotant criteria when evaluating a product or a service(Foo et al., 2000) -Customer service has a strong link to customer satisfaction, which then yields customer loyalty and long-term profitability(Szymanski ＆ Henard, 2001： McKenna, 1991)(omitted)