• Journal of Chest Surgery
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• 제14권1호
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• pp.1-8
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• 1981

Alterations in serum enzymes were studied in twenty-five patients who underwent open heart surgery in N.M.C. during the period from June 1979, to Feb. 1980. There were fifteen congenital and ten acquired heart diseases. In all patients, Rygg-Kyvsgaard five head roller pump and Polystan bubble oxygenator were used and serial determination of total level of Creatine phosphokinase [CPK], Lactic dehydrogenase [LDH], Glutamic oxaloacetic transaminase [SGOT] were made preoperatively, operation day [just after aortic clamp release, 2 hrs later, 4 hrs later, 6 hrs later], and postoperative days up to 5th day. Immediate postoperative clinical courses were also evaluated. Twenty-five patients were divided into two groups: Group A[13] was cardiopulmonary bypass time more than 95 minutes and aortic clamp time more than 45 minutes. Group B[12] was cardiopulmonary bypass time less than 95 minutes and aortic clamp time less than 45 minutes. The peak levels of SGOT, LDH in Group A were more significantly elevated than Group B [P<0.05]. But peak levels of CPK were not significant between two groups. In the view of clinical evaluation, poor clinical courses were more frequent in Group A [54%] than Group B[8%].

• Journal of Chest Surgery
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• 제19권2호
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• pp.181-187
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• 1986

The changes of serum creatine phosphokinase [CPK], serum lactic dehydrogenase [LDH], serum glutamic oxaloacetic transaminase [GOT] and serum glutamic pyruvic transaminase [GPT] were studied in a total of 82 cases who underwent open heart operation under the cardiopulmonary bypass at the Department of Thoracic and Cardiovascular Surgery, Chungnam National University Hospital. The results were as follows 1. The average values of CPK and COT after the operation were reached to the maximal values on the first postoperative day, which were returned to the normal range until the fifth postoperative day. The average values of LDH and CPT after the operation were reached to the maximal values on the first and second postoperative day respectively, which were significantly increased until the seventh postoperative day. 2. In the relationship of the serum enzymes and duration of the extracorporeal circulation, the values on the group over 90 minute of the extracorporeal circulation were more increased than on the group below 90 minute of the extracorporeal circulation. 3. In the relationship of the changes of the serum enzymes and congenital heart diseases and acquired heart diseases, there were no significantly differences in the values between the two groups.

• 대한한방내과학회지
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• 제37권5호
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• pp.711-716
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• 2016

Objective: To report a case of rhabdomyolysis that occurred after spinning exercise. Methods: A patient diagnosed with rhabdomyolysis received Korean medical treatment and Western medical treatment for 6 days. We observed the patient for 13 days. Clinical symptoms were evaluated with a Numerical Rating Scale (NRS) and laboratory tests, which included Liver Functional Test (LFT), Renal Functional Test (RFT), creatinine phosphokinase (CPK), myoglobin, and urine tests. Results: After treatment, the clinical symptoms were improved. In this case, acute renal failure did not occur. Laboratory results, including AST, ALT, CPK, and LDH, were also improved. Conclusions: Rhabdomyolysis can be treated cooperatively with Korean and western medical cooperative treatment.

• 대한약침학회지
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• 제13권2호
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• pp.131-138
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• 2010

Objective : This is a clinical report about the 77-years-old man patient with polymyositis treated by oriental medicine. Methods : The patient was treated by acupuncture and herb medication. The improvement of the patient was judged by MRC scale and CPK, LDH. Results & Conclusions : 1. Patient's symptoms(paraplegia) rapidly improved. 2. The level of CPK, LDH and Potassium are recovered to the normal range. 3. Associated with respiratory symptoms are getting better.

• Archives of Pharmacal Research
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• 제13권4호
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• pp.298-305
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• 1990

Based on equal number of cells, supplementation of 10$^{-6}$ M cadimium highly simulated the intracellular amylase. GCT, LDH as well as the glucose and erea content of E carotovora var, carotovaro cells. This was coupled with initiation of highly active GOT, CPK as well as accumulation of cholesterol in the cells. Lanthanum was less active and unable to initiate COT or CPK. Nickel was almost without effect though reduced LDH activity without initiating either enzyme or cholesterol production. Similar stiulations and/or initiations were observed, though to variable extents, when the same concentration of the three elements were supplied to E. carotovora var, citullis or E. toxica. The highest yield of amylase, GPT, GGT or glucose was obtained when E. carotovora var. carotovora was supplemented with Cd + Ni. The highest urea level was recorded in Erwinia carotovara var, cirullis, amended with Cd + La.

• 산업경영시스템학회지
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• 제28권4호
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• pp.116-123
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• 2005

The traditional process capability indices Cp, Cpk, Cpm, $Cpm^+$ have been used to characterize process performance on the basis of univariate quality characteristics. Cp, Cpk consider the process variation, Cpm considers both the process variation and the process deviation from target and Cpm+ considers economic loss for the process deviation from target. In manufacturing industry, there is growing interest in quantitative measures of process variation under multivariate duality characteristics. The multivariate process capability index incorporates both the process variation and the process deviation from target or considers expected loss caused by the process deviation from target. This paper proposes multivariate capability index based on the expected loss derived from multivariate normal distribution.

• 대한한의학회지
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• 제17권1호
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• pp.361-373
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• 1996

An attempt was made to study the effects of dangguibohyultang and Ssangbohwan on the muscle recovery from exhaustion after severe exercise. Before rats were given severe swimming exercise, Dangguibohyultang and Ssangbohwan were admisterd. Then, the blood lactate level, the serum activities of LDH, CPK and the serum levels of FFA and glucose were measured. The results were as follows; 1. The level of the blood lactate were significantly decreased in the group of Dangguibohyultang. 2. The activities of serum LDH were significantly decreased in the groups of Dangguibohyultang and Ssangbohwan. 3. The activities of serum CPK were significantly decreased in the groups of Dangguibohyultang and Ssangbohwan. 4. The levels of serum FFA were significantly decreased in the groups of Dangguibohyultang. 5. The levels of serum glucose were significantly increased in the groups of Dangguibohyultang and Ssangbohwan. According to the above results, it is concluded that Dangguibohyultang was more effective on the muscle recovery than Ssangbohwan in rats.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제45회 하계 정기학술대회 초록집
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• pp.83.2-83.2
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• 2013

정교한 생산 공정에 있어서 공정의 갑작스런 변동(Shift)나 점진적인 변화(Drift)에 대해서 얼마나 적절하게 대응하느냐는 생산 제품의 품질과 수율에 상당한 영향을 미친다. 이에 본 과제에서는 반도체 생산 공정에 따른 측정 결과를 분석하여 최상의 공정조건(Recipe)를 유지하기 위한 알고리즘을 개발하고, 개발된 알고리즘의 유효성 판단을 위한 시뮬레이션 툴을 개발하였다. 또한, 다양한 현장 조건을 충족할 수 있도록 사용자 임의의 데이타 구조를 정의하고, 기준 정보를 등록할 수 있도록 유연성이 부여된 사용자 UI를 개발하였다. 생산 설비로부터 공정 관련 데이타를 수집하고, 측정 설비로부터 계측데이타를 수집한 후, 사용자가 설계한 APC 로직에 의해 실시간 공정 제어가 가능한 시스템을 개발하여, 현장 엔지니어가 다양한 APC 로직을 설계하고 구현할 수 있도록 하였다. 현장 엔지니어용 툴은 Graphical Workflow 형태로 개발되었으며, 엔지니어가 복잡한 프로그래밍을 하지 않아도 직관적으로 설계/구현할 수 있도록 하였다. 분석을 위한 리포트 화면을 이용하여, 공정/측정 데이타에 대한 조회기능을 제공하고, Trend, Pair, X-bar 등의 다양한 분석용 챠트를 이용하여 파라미터 분석 기능을 제공하였다. 본 과제에서 증착 장비용 제어 알고리즘을 적용하여 테스트하였으며, 30% 이상의 Cpk 개선 효과를 얻을 수 있었다.

• 셀메드
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• 제13권12호
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• pp.44.1-44.7
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• 2023

Objective: A case of reducing adverse effects associated with imatinib using Cyaplex F. Methods: The 52-year-old female with past medical history of stage 1 triple-positive breast cancer 10 years ago, and current metastatic melanoma has been complaining adverse effects after imatinib was started. Results: After OCNT was initiated, the patient's headache and muscle pain have been much tolerable and her AST/CPK levels were returned close to her baseline. Conclusion: OCNT may reduce side effects caused by Imatinib and help patient to stay with the current chemotherapy regimen.

• Journal of Pharmaceutical Investigation
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• 제32권2호
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• pp.87-93
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• 2002

This study is to enhance drug penetration via skin and investigate anti-inflammation effect following adoption of ultrasound. For this goal gel containing triamcinolone was prepared and the skin penetration rate and the change effects of blood plasma ingredients and serum enzyme were investigated. Using Franz type diffusion cell and the skin of hairless mouse, the permeation enhancing effect of ultrasound was tested. After the injury by direct trauma, the blood test was performed by measuring WBC, lymphocyte, and neutrophyl, and by analyzing CPK and LDH. The ultrasound transducer whose technical specification is geometric area(GA) $1.4\;cm^2$, effective radiation area(ERA) $0.8\;cm^2$, and beam non-uniformity ratio(BNR) 6.0 max was used. The influence of frequency having an effect on skin permeation rate was higher in the case of using 1MHz and continuous treatment. The temperature of receptor phase was not influenced in skin permeation by phonophoresis. Skin permeation increase attended by intensity of ultrasound, the permeation of triamcinolone was accelerated at $2.5\;w/cm^2\;than\;1.0\;w/cm^2$. Following muscle injury phonophoretic group the number of WBC, neutrophil and lympholyte were decreased significantly as compared with both control group and ultrasound group. The result of variation of serum CPK and LDH activity conformed to the phonophoretic effect as same pattern with the variation of WBC, neutrophil and lymphocyte.