• Proceedings of the Plant Resources Society of Korea Conference
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• 1999.10a
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• pp.46-57
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• 1999

Ginseng(Panax ginseng C.A. Meyer) is important medicinal plant but requires 4-year cultivation for root harvest because of slow growth. In contrast, ginseng callus and hairy roots grow vigorously and may Produce the same or more biologically active compounds for human health than natural ginseng roots. Therefore, ginseng callus and hairy roots can be used for commercial purposes. Polyacetylene, one of anti-cancer compounds in ginseng, was not detected in the callus cultured on the medium containing 2, 4-B, but cells derived from the callus growth was excellent, The ginseng calli cultured on the medium containing 2mg11 CPA and 0.05mg/1 BA was grown vigorously and produced panaxydol, one of ginseng polyacetylene. The biosynthesis of polyacetylene in callus was not affected by addition of NAA and sucrose in media. The SH medium was better than the MS medium for ginseng callus growth and biosynthesis of panaxydol. Another ginseng anti-cancer compounds, ginsenoside-Rg$_3$, Rh$_1$and Rh$_2$ were detected in ginseng hairy roots by heat treatment. Those of Panax ginseng were obtained after root disks of three-year old roots were infected with Agrobacterium rhizogenes Rl000 $A_4$T in dark condition after one month of culture. The optimum growth of hairy roots was achieved in the culture of 1/2 MS liquid medium in dark(22$^{\circ}C$) under 60 rpm gyratory shaking. Hairy roots grew well in 5 ι Erlenmeyer flasks, 1ι roller drums, 10ι jar-fermenters, and especially in 20ι air-lift .culture vessels. All heat treatments had remarkably different ginsenoside contents. Eleven ginsenosides were determined in heat treatment, eight in freeze dried hairy roots. Contents of ginsenoside-Rbl , Rb2, Rc, Rd. Re, Rf, and Rg$_1$tested in all heat treatments were less than those of freeze dried hairy roots. Contents of glnsenoside-Rg$_2$ in heat treatment for 1 hour at 105$^{\circ}C$ was 4.92mg/g dry wt, 3.9 times higher than 1.27 mg/g dry wt of freeze dried hairy roots. The optimum condition of heat treatment for the production of ginsenoside-Rg$_3$and Rhl was 2 hours at 105$^{\circ}C$, and ginsenoside content was 2.58mg/g dry wt and 3.62mg/g dry wt, respectively. The production of ginsenoside-Rh2 was the highest in heat treatment for 2 hours at 105$^{\circ}C$ among treatments examined, and ginsenoside-Rh$_2$content was 1.08mg/g dry wt.

• The Korean Journal of Pain
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• v.6 no.2
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• pp.231-236
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• 1993

Clonidine, a centrally-acting antihypertensive agent known to reduce central sympathetic outflow and modulate presynaptic transmitter's release, has shown to suppress central noradrenergic hyperactivity induced by immobilization stress in animals, by decreasing the MAC of halothane and the dose of narcotics required to prevent reflex cardiovascular response to noxious stimuli, and to have potent analgesic properties in humans. These characteristics suggest that clonidine might be a useful adjunct to the anesthetic management of patients with preexisting hypertension. Accordingly, we determined the clinical efficacy and safety on analgesia, sedation and hemodynamic stability in the perioperative period. Thirty patients(ASA physical status II-III) with a history of arterial hypertension, scheduled for elective orthopedic surgery were randomly assigned to two groups. We applied CPA-clonidine patch($6.9\;mg/cm^2$, 0.2 mg delivered daily) or placebo patch to each groups, 48 hours prior to induction of anesthesia. Antihypertensive medication was continued until the morning of the scheduled surgery. All patients received premedication of atropine and lorazepam, and induced anesthesia with thiopental and succinylcholine, and maintained with enflurane and 50% nitrous oxide, while sustaining the BP and pulse rate at acceptable range. For the relief of pain postoperatively, diclofenac and fentanyl were administered intramuscularly on demand. The results were as follows: 1) The change of hemodynamic responses in clonidine group was less compared to the placebo group. 2) Intraoperative anesthetic requirement for enflurane in clonidine group were significantly lower than placebo group. 3) Postoperative analgetic requirement in clonidine group were significantly lower than placebo group. In clonidine group, 5 cases out of 15 cases were required no analgetics, and the incidence of administration of additional fentanyl was decreased to 5 cases, comparing with 10 cases in placebo group.

• International Commerce and Information Review
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• v.18 no.1
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• pp.55-78
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• 2016

This paper discusses on Electronic Payment System between U.S.A. and Canada. In particular, I focused on ACSS compare with FedACH(Fed Automated Clearing House) to advance a research effects. Because both of them is a low-value, high-volume retail payment system which their countries represent. The ACSS(Automated Clearing Settlement System) is the system through which the vast majority of CPA payment items are cleared, through various payment streams. In 2014, ACSS system cleared approximately 6.8billion payments worth a total value of $ 44.9 trillion. While, The FedACH Network are the center of America Commerce, moving more than $40 trillion each year. That's made up of almost 23 billion electronic financial transaction, including direct deposit via ACH, social security and government benefits, electronic bill payments such as utility and mortgage payments. Thus in this article, first of all, I considered features of payment system and the types of payment items between ACSS and FedAch. Second, I analyzed the status of central bank and legal background. Third, I focused on the operational policy and risk aversion policy. Lastly, I suggested that their payment and banking system have to assume, with good reason, more efficiently accurately and securely operation to protect their customer from credit risk and financial fraud.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.27 no.5
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• pp.993-1000
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• 2017

When the availability of embedded device is considered, combined countermeasure such as first-order masking and hiding countermeasures is quite attractive because the security and efficiency can be provided at the same time. Especially, combined countermeasure can be applied to the confusion and diffusion layers of the first and last rounds in order to provide the efficiency. Also, the middle rounds only employs first-order masking countermeasure or no countermeasure. In this paper, we suggest a novel side channel analysis with low complexity in the output of diffusion layer. In general, the attack target cannot be set to the output of diffusion layer owing to the high complexity. When the diffusion layer of block cipher is composed of AND operations, we show that the attack complexity can be reduced. Here, we consider that the main algorithm is SEED. Then, the attack complexity with $2^{32}$ can be reduced by $2^{16}$ according to the fact that the correlation between the combination of S-box outputs and that of the outputs of diffusion layer. Moreover, compared to the fact that the main target is the output of S-box in general, we demonstrate that the required number of traces can be reduced by 43~98% in terms of simulated traces. Additionally, we show that only 8,000 traces are enough to retrieve the correct key by suggested scheme, although it fails to reveal the correct key when performing the general approach on 100,000 traces in realistic device.

• Journal of Korean Neurosurgical Society
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• v.30 no.sup1
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• pp.120-123
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• 2001

Objectives : The present study was performed to analyze results of hydroxyurea treatment for unresectable and recurrent meningiomas as adjuvant chemotherapeutic agent. Material and Methods : Among 87 cases of meningioma patients who treated surgically between Jauary 1988 and December 1997 in our department, unresectable and recurrent cases were 4 cases. Histologically, 3 cases were meningothelial type, 1 case was angiomatous type. Tumor orgin was cerebellopontine angle(CPA) in 3 cases, cavernous sinus in 1 case. Three of 4 cases received radiation treatment. All patients received a daily dosage of 20mg/kg/day of hydroxyurea. Hematological monitorning was performed monthly and tumor measurement was assessed by MR imaging before treatment and every 6 months. Mean follow-up period was 34 months. Rerults : All cases showed no enlargement of tumor mass without any shrinkage. Trigeminal neuralgia in 1 case was improved and external herniation of brain on craniectomy site in 1 case was shrunken. None of the patients had any serious side effects. White blood cell count fell below $3000/{\mu}l$ in 1 case, but recovered 2 weeks later with cessation of medication. Conclusion : Hydroxyurea stopped cell growth by triggering the apoptotic cascade. Our preliminary data indicate that hydroxyurea provides adjuvant medical treatment in patients of unresectable and recurrent meningiomas

• Korean Journal of Breeding Science
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• v.43 no.1
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• pp.50-55
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• 2011

The introduction of doubled haploid (DH) approach into breeding programs has reduced the times and population sizes required for the production of pure lines. We carried out the experiment for development on effective method of producing haploid in wheat. Emasculated spikelets of wheat were pollinated with maize pollen and cultured in the solution containing 40 g/L sucrose and 2,4-D, NAA, 2,4,5-T and dicamba 24 h after pollination, and then incubated until embryo rescue. Fourteen to sixteen days after pollination, the embryos are excised and cultured in half-strength MS basal medium supplemented with 20 g/L sucrose and 1 mg/L NAA. The type of plant growth regulators was found to be most significant in production of haploid plants. The application of synthetic auxins to pollinated florets, stimulates haploid embryo development to a stage where the embryos can be rescued onto nutrient media. The percentage of seeded florets was significantly affected by 100 mg/L 2,4-D, 150 mg/L 2,4,5-T and 50 mg/L dicamba. The percentage of embryos formed was significantly increased by treatment with 2,4-D and 2,4,5-T at 100 mg/L, and dicamba at 50 mg/L, but the treatments with 150 mg/L 2,4-D inhibited embryo development and plant regeneration. The optimum application time of plant growth regulators was 24 hrs after pollination.

• Journal of the Korea Society of Computer and Information
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• v.11 no.3
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• pp.117-124
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• 2006

In this paper, we propose the optimal migration path searching method including path adjustment and reassignment techniques for an efficient migration of mobile agent which has an autonomous ability for some task processing. In traditional agent system, if the various and large quantify of task processing were required from the users, it could be derive excessive network traffic and overload due to increasing the size of agent. And also, if an agent migrates from node to node according to routing schedules specified by the user at which the most of network traffic occurs, it could not actively cope with particular situations such as communication loss and node obstacles and required much cost for node traversal Therefore. this paper presents the migration method of agent which can try to adjust and reassign path to the destination automatically through the optimal path search using by network traffic perception in stead of the passive routing schedule by the user. An optimal migration path searching and adjustment methods ensure the migration reliability on distributed nodes and reduce the traversal task processing time of mobile agent by avoiding network traffic paths and node obstacles.

• The Journal of the Korea Contents Association
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• v.21 no.10
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• pp.550-563
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• 2021

This study recognizes that the externalizing problem behaviors of child with disabilities are the result of the social interaction between mother and child, and empirically verifies its systematic causal structure and multidimensional influence relationship. It was attempted to derive practical implications that can help the smooth normalization process of children's families. Therefore, 135 children with disabilities and their mothers selected by convenience sampling were targeted, and in the relationship between maternal overprotective parenting and externalizing behaviors of child, effortful control was used as a mediating variable, and defense style of mothers and children was used as a moderating variable. A Conditional Process Analysis(CPA) that can verify the moderated mediation Effect was performed by establishing a research model. As a result of the analysis, first, the overprotective parenting behavior of mother was statistically significant in both direct and indirect effects in increasing externalizing behaviors of child, and the mediation effect by effortful control was also statistically significant. Second, it was confirmed that the moderated mediation effect of effortful control by the mother's defense style was statistically significant, and the moderated mediation effect of effortful control by the child's defense style was not statistically significant. Based on the above results, assuming the importance of the influence of maternal parenting, a direct strategy for change in maternal overprotective parenting, child's Practical implications of parallel strategies with the tendency toward effective control and suboptimal strategies through the application of mothers' coping strategies were discussed.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.18 no.2
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• pp.39-47
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• 2008

Among previous Side Channel Analysis (SCA) methods, Differential Power Analysis (DPA) based on the statistical characteristics of collected signals has been known as an efficient attack for uncovering secret key of cryptosystems. However, the attack performance of this method is affected very much by the temporal misalignment and noise of collected side channel signals. In this paper, we propose a new method to surmount the noise problem in DPA. The performance of the proposed method is then evaluated while analyzing the power consumption signals of Micro-controller chips during a DES operation. Its performance is then compared to that of the original DPA in the time and frequency domains. When we compare the experimental results with respect to the needed number of traces to uncover the secret key, our proposed method shows the performance enhancement 33% in the time domain and 50% in the frequency domain.

• Structural Engineering and Mechanics
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• v.78 no.1
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• pp.41-52
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• 2021

Inelastic static pushover analysis has been used in the academic-research widely for seismic analysis of structures. Nowadays, the variety pushover analysis methods have been developed, including Modal pushover, Adaptive pushover, and Cyclic pushover, in which some weaknesses of the conventional pushover method have been rectified. In the conventional pushover analysis method, the effects of cumulative growth of cracks are not considered on the reduction of strength and stiffness of RC members that occur during earthquake or cyclic loading. Therefore, the Cyclic Pushover Analysis Method (CPA) has been proposed. This method is a powerful technique for seismic evaluation of regular reinforced concrete buildings in which the first mode of them is dominant. Since the bridges have different structures than buildings, their results cannot necessarily be attributed to bridges, and more research is needed. In this study, a cyclic pushover analysis with four loading protocols (suggested by valid references) by the Opensees software was conducted for seismic evaluation of two regular reinforce concrete bridges. The modeling method was validated with the comparison of the analytical and experimental results under both cyclic and dynamic loading. The failure mode of the piers was considered in two-mode of flexural failure and also a flexural-shear failure. Along with the cyclic analysis, conventional analysis has been studied. Also, the nonlinear incremental dynamic analysis (IDA) method has been used to examine and compare the results of pushover analyses. The time history of 20 far-field earthquake records was used to conduct IDA. After analysis, the base shear vs. displacement in the middle of the deck was drawn. The obtained results show that the cyclic pushover analysis method is able to evaluate an accurate seismic behavior of the reinforced concrete piers of the bridges. Based on the results, the cyclic pushover has proper convergence with IDA. Its accuracy was much higher than the conventional pushover, in which the bridge piers failed in flexural-shear mode. But, in the flexural failure mode, the results of each two pushover methods were close approximately. Besides, the cyclic pushover method with ACI loading protocol, and ATC-24 loading protocol, can provided more accurate results for evaluating the seismic investigation of the bridges, specially if the bridge piers are failed in flexural-shear failure mode.