• BMB Reports
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• v.55 no.6
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• pp.251-258
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• 2022

Innovative genome editing techniques developed in recent decades have revolutionized the biomedical research field. Liver is the most favored target organ for genome editing owing to its ability to regenerate. The regenerative capacity of the liver enables ex vivo gene editing in which the mutated gene in hepatocytes isolated from the animal model of genetic disease is repaired. The edited hepatocytes are injected back into the animal to mitigate the disease. Furthermore, the liver is considered as the easiest target organ for gene editing as it absorbs almost all foreign molecules. The mRNA vaccines, which have been developed to manage the COVID-19 pandemic, have provided a novel gene editing strategy using Cas mRNA. A single injection of gene editing components with Cas mRNA is reported to be efficient in the treatment of patients with genetic liver diseases. In this review, we first discuss previously reported gene editing tools and cases managed using them, as well as liver diseases caused by genetic mutations. Next, we summarize the recent successes of ex vivo and in vivo gene editing approaches in ameliorating liver diseases in animals and humans.

• Journal of Distribution Science
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• v.20 no.11
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• pp.47-59
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• 2022

Purpose: The study aims to synthesize research trends regarding the distribution of 'other customer perception' on 'brand experience'; concurrently, to identify the promising research directions and suggest useful for managers. Research design, data, and methodology: The paper deals with the distribution of 'other customer perception' on 'brand experience' through evaluating a systematic review combined with biological mapping analysis (VOS viewer) with 226 documents published in 142 journals from 1987 to 2021. Results: The study synthesizes and analyzes existing literature reviews on the distribution of 'other customer perception' on 'brand experience', which mainly highlights three research topic groups. Exploring the component of relationship should be considered in the brand experience scale when the research context is the social interactions surrounding the customer's purchasing process. Moreover, the presence of mindfulness in several publications has suggested a potential research direction in the consumer behavior field. Conclusions: The systematic reports can be a useful reference for managers towards building brand experience based on distribution of 'other customer perception' with moderating of mindfulness - a new finding of behavioral interaction that has just experienced the Covid-19 pandemic which is experienced directly at the store and lead to many changes in consumer psychology.

• Journal of Korean Society for Quality Management
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• v.51 no.2
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• pp.203-221
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• 2023

Purpose: The purpose of the research is to explore the role of social media in attracting international patients for cosmetic services in South Korea during the COVID-19 pandemic. The study aims to conceptualize social media as an effective marketing tool for minimizing perceived risks associated with cosmetic services and increasing patient satisfaction. Methods: The study validated proposed hypotheses using the PROCESS macro for SPSS with overseas patients who received cosmetic treatment in private Korean plastic surgery clinics in Busan. Results: This study found that information delivery capability reduced perceived risk and contributed to patient satisfaction, while communication capability did not show any significant relationship with perceived risk and satisfaction. In addition, information delivery capability had a significant direct effect on patient satisfaction, but communication capability did not. Conclusion: It is expected that the outcomes of this study will broaden our understanding of the use of social media in reducing perceived risk and increasing satisfaction.

• Journal of IKEEE
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• v.28 no.2
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• pp.228-233
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• 2024

Due to the recent COVID-19 pandemic, various methods have been devised to prevent infections caused by physical contact. Among them, a non-contact button was developed to prevent infections in elevators, where many contacts occur in daily life. In this study, an active shield type capacitance sensor is used to detect changes in capacitance when a finger approaches. There is no static power consumption, and the relatively expensive ADC and MCU are reduced to one by sensing buttons every time using analog switches. In addition to the elevator buttons, this technology is expected to replace push-type buttons that many people contact in everyday life.

• Journal of Practical Engineering Education
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• v.16 no.3_spc
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• pp.267-274
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• 2024

One challenge with teaching practical programming classes is the standardization of development tools on student computers. This is particularly true when a complicated setup process is required before beginning to code, or in remote classes, such as those necessitated by the COVID-19 pandemic, where the instructor cannot provide individual troubleshooting assistance. In such cases, students who encounter problems during the setup process may give up on the class altogether before even beginning to code. Therefore, this paper recommends using GitHub Codespaces as a tool for implementing standardized student development environments from day one. Codespaces provides Docker containers that an instructor can configure in such a way as to enable students to practice installing various coding tools within a controlled space, while also providing a language-specific, fully optimized development environment. In addition, Codespaces may be used more effectively in collaboration with GitHub Classroom, which helps instructors manage both the starter code and coding environment in which students work. In this paper, we compare two semesters of university Node.JS programming classes that utilized different development environments: one localized on student computers, the other containerized in Codespaces online. Then, we discuss how GitHub Codespaces and GitHub Classroom can be used to increase the effectiveness of practical programming classes while also increasing student engagement and programming confidence in class.

• Journal of the Korean Applied Science and Technology
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• v.38 no.6
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• pp.1393-1404
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• 2021

The current study was conducted to understand the status of infection management through a survey on the status of awareness and performance of infection management and to improve efficient infection management and education programs of workers in long-term care institutions. The subjects of the study were 134 workers at 35 long-term care institutions in the C region, and data were collected from July 12 to 30, 2021. They agree to participate in research self reported structured questionnaire by SPSS program ver. 22.0. As a result of the study, the subject's awareness of infection management appeared to be a difference in accordance with occupation (F=3.181, p=.032) and education experience (F=6.372, p=.013). Also, factors influencing the subject's performance of infection management were occupation (F=3.972, p=.010) and education experience (F=4.403, p=.038). The relationship between awareness of infection management and performance resilience fined out a significantly positive correlation (r=.919, p<.001). As a result, for patient safety in long-term care institutions in the COVID-19 pandemic situation, it is very important for workers not only to recognize the importance of infection management but also to directly perform infection management activities. To this end, regardless of the size of the institution, it is necessary to prepare a systematic and continuous curriculum by occupation and educational topic, and to legally strengthen the evaluation system to improve the quality of the infection management system.

• Journal of Korea Society of Industrial Information Systems
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• v.28 no.4
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• pp.59-76
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• 2023

This study examines critical issues and topics related to services using YouTube videos and research publications. We analyzed 2,853 YouTube videos and 19,973 research papers related to services, released during the 2013-June, 2023 period, using text mining and network analysis. In addition, the collected data was divided into pre- and post-COVID-19 pandemic periods to explore how key issues and topics regarding services have changed. These papers were sequentially analyzed through text mining and network construction and procedures. The results indicate that the central themes of YouTube videos were IT, data, and solution, while academic research focused on service quality, quality, and customer satisfaction. Regarding ego network analysis, the key issues in YouTube video contents revolved primarily around words related to the service industry. Although it was found that they generally lacked specific industry fields, academic papers explored diverse issues in various service fields. The results of this study can be utilized to understand changes in customer concerns in the service industry from practical and academic perspectives.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.10a
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• pp.493-495
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• 2022

This video is based on the newly emerged next-generation Media 360 VR. With the development of technology, digital content has developed and the opening of the COVID-19 pandemic untact era, people have found content that they can enjoy without going directly. 360 VR is a next-generation media that allows users to enjoy content in a three-dimensional manner as if they went to the site without having to go to the site. Using this, we would like to study the effective creation of local promotional videos.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2022.06a
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• pp.383-384
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• 2022

Following the development of technologies such as digital twin, IoT, and AI after the 4th industrial revolution, decision-making problems are being solved based on high-dimensional data analysis. This has recently been applied to the port logistics sector, and a number of studies on big data analysis, deep learning predictions, and simulations have been conducted on container terminals to improve port productivity. These high-dimensional data analysis techniques generally require a large number of data. However, the global port environment has changed due to the COVID-19 pandemic in 2020. It is not appropriate to apply data before the COVID-19 outbreak to the current port environment, and the data after the outbreak was not sufficiently collected to apply it to data analysis such as deep learning. Therefore, this study intends to present a port data augmentation method for data analysis as one of these problem-solving methods. To this end, we generate the container stowage situation of the yard through a generative adversarial neural network model in terms of container terminal operation, and verify similarity through statistical distribution verification between real and augmented data.

• Journal of Environmental Science International
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• v.32 no.12
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• pp.979-985
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• 2023

After the outbreak of COVID-19, the demand for home-enjoyable video games has surged, driven by extended pandemic conditions and resulting in rapid graphic technology advancements. Consequently, games with diverse expression techniques have emerged, captivating players. Virtual Reality (VR) environments predominantly feature natural landscapes, with advancing graphic technology enabling lifelike scenes. The rise in individuals seeking solace through natural elements in games has followed suit. As VR technology and metaverse interest grow, more people are exposed to digital imagery. However, evidence on the influence of graphic expression methods on emotional response to that is lacking. Our study examined user emotional responses, focusing on natural landscapes in digital graphics of games. Analyzing a group of 47 young adults as frequent digital media consumers, we studied reactions to different image styles (Realism, Semi-Realism, Stylized). In the analysis, Realism-style images were perceived the most positively, while emotional responses to natural landscapes with different graphical expressions showed no significant differences. Results suggest that recognizing digital natural landscapes may outweigh expression style impacting the evaluation of digital nature. This study's empirical analysis enhances the understanding of digital nature's application to actual situations.