• Journal of the Health Care and Life Science
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• v.9 no.1
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• pp.185-193
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• 2021

This study conducted a survey using Google Survey targeting 415 college students over the age of 20 to investigate college students' perceptions of the COVID-19 vaccine. As a result, the average result of 'I think the COVID-19 vaccination is necessary' for herd immunity was 3.90, and 65.8% of the 'necessity of vaccination' recognized the 'necessity of vaccination', but 35.4% negatively evaluated 'the safety of the vaccine'. showed. As for the intention to vaccinate against COVID-19, 34.7% said 'I will vaccinate as soon as the order arrives'. This showed that the current COVID-19 vaccination is not positive. As the reasons for not wanting to be vaccinated, 65.3% answered 'adverse reaction to the vaccine' and 25.8% 'distrust of the vaccine itself'. In addition, they perceived the vaccine supply between developed and underdeveloped countries as unequal, and the average was 3.94, indicating that they were afraid of adverse reactions to the COVID-19 vaccine. Therefore, in order to more effectively acquire information about the COVID-19 vaccine, research, platform development, and education on publicity methods through the media frequently used by college students are required.

• Journal of the Korea Convergence Society
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• v.13 no.1
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• pp.253-259
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• 2022

This study aims to provide a basis for preparing specific welfare measures for healthy lives of those who have lost vitality due to COVID-19 by identifying the Korean people's level of fear of COVID-19 and vaccine acceptability, and by examining people's life satisfaction. . The research results are as follows. First, the fear of coronavirus perceived by the survey subjects was found to be very high. Second, when compared to other vaccines against coronavirus, fear or fear of the vaccine was significantly higher. Third, the vaccine acceptance of adults perceived by the survey subjects was positive. Fourth, the reliability of the government policy on the coronavirus prevention vaccine was found to be relatively high. Fifth, in the evaluation of quality of life, economic satisfaction was lower than in other areas, and emotional satisfaction was found to be relatively high compared to other areas.

• Journal of Life Science
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• v.33 no.9
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• pp.746-753
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• 2023

Viral infectious diseases have been regarded as one of the greatest threats to global public health. The recent coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a stark reminder of the threat posed by emerging viral infections. Developing and producing appropriate and efficient vaccines and therapeutics are the only options to combat this pandemic. The COVID-19 pandemic has highlighted the need for novel vaccine platforms to control and prevent emerging viral diseases. Conventional vaccine platforms, including live-attenuated vaccine and inactivated vaccines, pose limitations in the speed of vaccine development, manufacturing capacity, and broad protection for emergency use. Interestingly, vaccination with the SARS-CoV-2 vaccine candidate based on the mRNA-lipid nanoparticle (LNP) platform protected against COVID-19, confirming that the nucleoside-modified candidate is a safe and effective alternative to conventional vaccines. Moreover, the prophylactic strategies against the COVID-19 pandemic have been mRNA nucleic acid-based vaccines and nanoparticle-based platforms, which are effective against SARS-CoV-2 and its variants. Overall, the novel vaccine platform has presented advantages compared with the traditional vaccine platform in the COVID-19 pandemic. This review explores the recent advancements in vaccine technologies and platforms, focusing on mRNA vaccines, digital vaccines, and nanoparticles while considering their advantages and possible drawbacks.

• Pediatric Infection and Vaccine
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• v.29 no.1
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• pp.37-45
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• 2022

Purpose: During the coronavirus disease 2019 (COVID-19) pandemic, we conducted a Delphi survey that included the experts from the field of COVID-19 immunization in children aged 5-11 years. The aim was to organize collective expert opinions on COVID-19 vaccination in young children in the Republic of Korea, and so thus assist the vaccination policy. Methods: The panels included pediatric infectious disease specialists, preventive medicine experts, infectious disease physicians, and COVID-19 vaccine experts consulting the Ministry of Health and Welfare. The Delphi survey was conducted online using a questionnaire from February 14 to February 27, 2022. Results: The Delphi panels agreed that children were vulnerable to COVID-19, and the severity of illness was modest. Furthermore the panels reported that children with chronic illness were more susceptible to a worsening clinical course. There were generally positive opinions on the effectiveness of COVID-19 vaccination in children aged 5-11 years, and experts gathered a slightly positive opinion that the adverse events of pediatric COVID-19 were not numerous. The benefits of COVID-19 vaccination were evaluated at a level similar to the potential risks in children. Currently, the only approved mRNA platform vaccine in children seemed to be sustainable; however, the recombinant protein platform COVID-19 vaccines were evaluated as better options. Conclusions: Due to the surge of the Omicron variant and an increase in pediatric cases, the COVID-19 vaccination in young children may have to be considered. Panels had neutral opinions regarding the COVID-19 vaccination in children aged 5-11 years. Thus monitoring of the epidemiology and the data about the safety of COVID-19 vaccination should be continued.

• The Korean Journal of Applied Statistics
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• v.36 no.5
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• pp.447-455
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• 2023

COVID-19 is an emerging infectious disease that is hard to predict in terms of fatality rate, treatments, and the timing of its end. World is developing treatments and vaccines for COVID-19. Several treatments and vaccines currently have emergency use authorization, but the treatments are only allowed for critically ill patients with COVID-19. Therefore, the aim of this study is to analyze the confirmed cases of COVID-19, including mortality and testing, in OECD countries and to assess the effect of vaccination on mortality. Looking at the confirmed cases, mortality, and vaccination rates of COVID-19, the number of confirmed cases was lower than previously reported cases after full vaccination. In early 2022, with Omicron, the confirmed cases increased sharply, while mortality dropped, and the mortality showed a gentle curve as the cumulative fully vaccinated exceeded 50%. This indicates that COVID-19 vaccines have an effect on reducing mortality. However, the duration of effectiveness of vaccines was considerably short, which decreased the initial inoculation effect and increased the monthly mortality. As this study was carried out during the COVID-19 pandemic, there was not enough data to analyze comprehensively. However, it is meaningful to compare and analyze the impact of COVID-19 by country.

• Journal of the Korea Convergence Society
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• v.12 no.11
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• pp.347-357
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• 2021

Since the outbreak of Covid-19, many countries have tried to defense Covid-19 to protect their people and as an influential and reliable policy as of now, they have recommended vaccinating. Thus, this research explored what influences the intention to vaccinate against Covid-19 with three health locus of control from multi-dimension health locus of control (MHLC) and perceived susceptibility and severity from health belief model (HBM) through PLS path modeling. Consequently, chance locus of control (CHLC) influence indirectly intention to vaccinate against Covid-19 mediating with susceptibility perception. It implies that the more fatalistic people attitude toward Covid-19, the more susceptible they perceived to the disease, and then, the stronger intention to vaccinate they would have. Thus, the health promotion authorities should motivate to activate people's susceptibility perception toward the disease through utilizing a variety of policies and consider that the fatalistic tendency toward the disease of people could play an antecedent role in the process.

• The Journal of the Convergence on Culture Technology
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• v.7 no.3
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• pp.163-171
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• 2021

This study aimed to investigate the main characteristics of the COVID-19 vaccine-related videos spread on YouTube and differences in user responses in the infodemic situation caused by COVID-19. As a result of content analysis of 579 videos related to the COVID-19 vaccine, it was found that all of the false information was written by individual channels. Institutions, organizations, media companies, and government channels reported spread of false information as well as fact-oriented reporting. The progressive channel had a high percentage of positive sentiment in favor of vaccination, and the conservative channel had a high percentage of negative emotion against vaccination. After the vaccination started, the number of videos on government channels increased, and it was found that the number of videos with positive emotions increased. Results of regression analysis of video characteristics that affect the number of likes indicated that personal expert videos and videos from progressive channels received more likes. Combining the research results, we propose a plan to promote government policies regarding the COVID-19 vaccine using social media.

• Journal of Korean Academy of Nursing
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• v.53 no.2
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• pp.208-211
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• 2023

Purpose: This study aimed to investigate COVID-19 vaccination intentions in Korean parents for their children aged 5 to 11 years and the factors influencing them. Methods: A cross-sectional online survey of 363 parents of children aged 5 to 11 years was conducted in Korea in April 2022. Data were analyzed using independent t-test, χ² -test, Fisher's exact test, and hierarchical logistic regression analysis using SPSS/WIN 26.0 and MedCalc software version 20.113. Results: Of 363 Korean parents with children aged 5 to 11, 42.4% intended to vaccinate their children. Significant factors influencing vaccination intention were the second or third birth order of children (OR = 3.45, 95% CI = 1.45~8.21), vaccine hesitancy-confidence (OR = 2.00, 95% CI = 1.51~2.65), vaccine hesitancy-collective responsibility (OR = 1.57, 95% CI: 1.10~2.25), and COVID-19 anxiety-avoidance (OR = 1.55, 95% CI = 1.13~2.11). Conclusion: Findings suggest that COVID-19 vaccine campaigns based on reliable information and evidence from health authorities are needed to increase COVID-19 vaccination. Well-designed health communications for the target population may help to increase parental vaccine acceptance.

• Journal of the Korean Society for information Management
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• v.38 no.4
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• pp.113-128
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• 2021

In this study, we aimed to understand the public opinion on COVID-19 vaccine. To achieve the goal, we analyzed COVID-19 vaccine-related Twitter posts. 45,413 tweets posted from March 16, 2020 to March 15, 2021 including COVID-19 vaccine names as keywords were collected. The 12 vaccine names used for data collection included 'Pfizer', 'AstraZeneca', 'Modena', 'Jansen', 'NovaVax', 'Sinopharm', 'SinoVac', 'Sputnik V', 'Bharat', 'KhanSino', 'Chumakov', and 'VECTOR' in the order of the number of collected posts. The collected posts were analyzed manually and automatedly through keyword analysis, sentiment analysis, and topic modeling to understand the opinions for the investigated vaccines. According to the results, there were generally more negative posts about vaccines than positive posts. Anxiety about the aftereffects of vaccination and distrust in the efficacy of vaccines were identified as major negative factors for vaccines. On the contrary, the anticipation for the suppression of the spread of coronavirus following vaccination was identified as a positive social factor for vaccines. Different from previous studies that investigated opinions about COVID-19 vaccines through mass media data such as news articles, this study explores opinions of social media users using keyword analysis, sentiment analysis, and topic modeling. In addition, the results of this study can be used by governmental institutions for making policies to promote vaccination reflecting the social atmosphere.

• Pediatric Infection and Vaccine
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• v.29 no.1
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• pp.28-36
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• 2022

Purpose: To evaluate the efficacy and safety of coronavirus disease 2019 (COVID-19) vaccines in children aged 5-11 years, a rapid systematic review was conducted on published clinical trials of COVID-19 vaccines and studies that analyzed real-world data on adverse events after COVID-19 vaccination. Methods: A systematic search was conducted on medical literature in international (Ovid-MEDLINE) and pre-published literature databases (medRxiv), followed by handsearching up to January 4, 2022. We used terms including COVID-19, severe acute respiratory syndrome coronavirus 2, and vaccines, and the certainty of evidence was graded using the GRADE approach. Results: A total of 1,675 studies were identified, of which five were finally selected. Among the five studies, four consisted of data from clinical trials of each of the four types of COVID-19 vaccines (BNT162b2, mRNA-1273, CoronaVac, and BBIBP-CorV). The remaining study consisted of real-world data on the safety of the BNT162b2 vaccine in children aged 5-11 years. This systematic review identified that COVID-19 vaccines in recipients aged 5-11 years produced a favorable immune response, and were vaccines were effective against COVID-19. The safety findings for the BNT162b2 vaccine in children and early adolescents aged 5-11 years were similar to those data noted in the clinical trial. Conclusions: There is limited data on COVID-19 vaccines in children aged 5-11 years. Consequently continuous and comprehensive monitoring is necessary for the evaluation of the safety and effectiveness of the COVID-19 vaccines.