• Journal of Mechanical Science and Technology
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• 제18권5호
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• pp.808-813
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• 2004

The stress analysis on orthotropic composite cylindrical shells with one circular or one elliptical cutout subjected to an axial force is carried out by using an analytical and experimental method. The composite cylindrical shell governing equation of the Donnell's type is applied to this study and all results are presented by the stress concentration factor. The stress concentration factor is defined as the ratio of the stress on the region around a cutout to the nominal stress of the shell. The stress concentration factor is classified into the circumferential stress concentration factors and the radial stress concentration factors due to the cylindrical coordinate of which the origin is the center of a cutout. The considered loading condition is only axial tension loading condition. In this study, thus, the maximum stress is induced on perpendicular region against axial direction, on the coordinate. Various cutout sizes are expressed using the radius ratio, (equation omitted), which is the radius of a cutout over one of the cylindrical shell. Experimental results are obtained using strain gages, which are attached around a cutout of the cylindrical shell. As the result from this study, the stress concentration around a cutout can be predicted by using the analytical method for an orthotropic composite cylindrical shell having a circular or an elliptical cutout.

• 한국운동역학회지
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• 제15권3호
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• pp.9-19
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• 2005

The purpose of this study was to analyze the effects of three different types of preparatory movement(squat, countermovement and hopping) in sideward responsive propulsion movement. 7 healthy subjects performed left and right side movement task by external output signal. 3D kinematics were analyzed The results were followed First, performance time in the countermovement and hopping conditions was shorter(10-20%) than that in the squat condition. The hopping condition that is more related to pre-stretch showed excellent performance. Second, time difference between after turned on the external signal and until take off was the primary factor in performance results among movement conditions. The preparatory phase before the propulsive phase in the squat condition produced more time than that in other conditions. The hopping condition showed the most short time in both the preparatory and the propulsive phase, therefore it was advantage for performance result Third, significant difference was not found in take-off velocity among movement conditions although there was difference of the time required in the propulsive phase. The maximum acceleration in the propulsive phase was larger in order of the hopping. countermovement, and squat condition. The countermovement and hopping conditions showed high take-off velocity although the propulsive phase in those conditions was shorter than that in squat condition. The pre-stretch by preparatory countermovement was considered as the positive factor of producing power in concentric contraction. Fourth, the hopping condition produced large angular velocity of joints. In hopping condition, large amount of moment for rotation movement was revealed in relatively short time and it was considered to cause powerful joint movements. In conclusion, the hopping movement using countermovement is advantage of responsive propulsion movement. It is resulted from short duration until take off and large amount of joint moment and joint power in concentric contraction by pre-stretch.

• Design & Manufacturing
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• 제11권1호
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• pp.50-54
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• 2017

In this study, researches were conducted as follows. First, as the basic experiment, the cutting speed, feedrate, and the depth of cut were set as the process parameters, and by setting the surface roughness as the factor of measurement for each of the combinations, and the analysis about cutting tendency of the material was conducted by proceeding the turning process of Co-Cr-Mo alloy. Second, by setting the feature of the surface roughness according to the 'turning processing condition' that was confirmed in the previous experiment, and by applying the Taguchi Method, the conditions that influence the features of the surface roughness according to the 'turning processing condition' of Co-Cr-Mo was analyzed, and also by measuring the surface roughness according to each of the 'cutting conditions', the optimal processing condition was generated. As the result of analysis, it was possible to understand that the factor that mostly affects the surface roughness was the cutting speed, followed by the dept of cutting and transfer speed, and as for the optimal processing condition, it was possible to find that the cutting speed was 5,000rpm, and the depth of cut was 0.1mm, and the feedrate was 0.003mm/rev, and the value of the surface roughness at this point is $0.197{\mu}m$.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2014년도 추계학술대회 논문집
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• pp.960-965
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• 2014

Transmission loss of specimen is calculated by measuring energy of incident and transmission and using reverberant room of large size. But normal measurement of transmission loss has trouble because it is actually demanded that large area and specimen of certain size is satisfied with condition of diffused sound field. Especially, in case of mechanical component, interested frequency band is mid-frequency band between 500 ~ 2k Hz, and it is used to be available to minimize a reverberation chamber under conditions satisfying acoustic one because production of specimen for transmission loss measurement has limit. But, as in semi-reverberation room, it is difficult to satisfy condition of diffuse sound field and modification factor is applied to complement that. Correction factor when measuring transmission loss using semi-reverberation chamber is required accuracy because it works as main factor determining reliability of reuslts on transmission loss. In this study, it is analyzed that an effect on correction factor based on varying materials and sizes of specimens in order to deduction of it. Also It is confirmed that applied by elicited correction factor with actual railway vehicle's floor has reliability.

• 한국산업보건학회지
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• 제29권3호
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• pp.343-350
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• 2019

Objectives: This study aims to identify whether ventilation conditions and their effectiveness can be significantly improved in an experimental chamber by increasing the mixing factor (K-Factor). Methods: In a chamber with a volume of $1m^3$, air velocity was measured at six different points with four roof fans in the upper part of the chamber being operated in order. The impact of the ventilation conditions was analyzed when the flow rates were increasing and the first inlet of the chamber was either open or closed. Smoke patterns were also observed at four corner points where ventilation was limited. Kruskal Wallis and Mann-Whitney tests were performed to compare air velocities measured in the chamber. Results: The air velocities measured at only the third point increased significantly from $0.03{\pm}0.03m/s$ (door open) and $0.05{\pm}0.06m/s$ (door closed) with two fans, $0.08{\pm}0.08m/s$ with three fans, and $0.09{\pm}0.09m/s$ with four fans operating (p<0.05). However, air velocities at the four corner points did not significantly increase. Smoke patters also showed that the open inlet of the chamber had no effect on improvement of ventilation conditions and effectiveness. Conclusions: In this study, the air velocities at six points in the chamber did not significantly increase despite the increase in the mixing factor and flow rates of ventilation in the controlled environment. Therefore, the inflow of outdoor air throughout an open inlet and installation of a forced ventilation system can potentially increase the indoor air velocity and improve ventilation condition without an increase in the mixing factor.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.228.2-229
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• 2003

Estrogen Receptor is a ligand-activated transcription factor. The concentration of the receptor is a major component that regulates expression of estrogen-responsive genes. We have studied mechanism of estrogen receptor alpha (ER${\alpha}$) downregulation by HIF-1 using HIF-1${\alpha}$/VP16 constructs. ER${\alpha}$ is known to be downregulated under hypoxic condition. Transcriptional response under hypoxia is mediated through Hypoxia-inducible factor-1 (HIF-1), a transcription factor that is usullaly degraded but stabilized under hypoxia. (omitted)

• 한국신뢰성학회지:신뢰성응용연구
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• 제10권1호
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• pp.25-38
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• 2010

In this paper, an accelerated degradation test procedure for an electronic appliance compressor is proposed. We investigate the amount of wear of the compressor and consider several factors as accelerating factors. Finally we select the operating pressure as a main accelerating factor. The test condition of accelerated degradation test is determined. The modified accelerating test reduces the test time in design phase by using the suggested accelerating factor.

• Clinical and Experimental Reproductive Medicine
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• 제30권1호
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• pp.65-75
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• 2003

Objectives: To investigate the role of TGF (Transforming growth factor-$\beta$) involved in the paracrinic communication during decidualization between UEC (uterine epithelial cells) and USC (uterine stromal cells), we have employed a co-culture system composed of human endometrial epithelial and stromal cells in defined hormonal conditions. Design: In the co-culture, endometrial epithelial cells cultured in the matrigel-coated cell culture insert are seeded on top of the endometrial stromal cells cultured within a collagen gel. The co-culture was maintained for 48 hours under the following hormonal conditions: progesterone dominant condition (100 nM P4 and 1 nM E2) or estrogen-dominant condition (100 nM E2 and 1 nM P4). 10 ng/ ml HGF and/or 10 ng/ml TGF-$\beta$1 are added. Methods: RT-PCR is utilized to detect mRNAs quantitatively. Enzyme-linked immunosorbent assay (ELISA) and immunohistochemical staining are utilized to detect proteins in the tissue. Results: Prolactin mRNA is expressed in the co-cultured stromal cells under the progesterone dominant condition. TGF-$\beta$1 and its receptors are expressed in both the co-cultured epithelial and stromal cells irrespective of the steroid present, which is in contrast with no or negligible expression of TGF-$\beta$1 or its receptor in cells separately cultured. Both estrogen and progesterone significantly elevate the concentration of hepatocyte growth factor (HGF) in the conditioned medium of the co-culture with the value of 4, 325 pg/ml in E2-dominant and 2, 000 pg/ml in P4-dominant condition compare to 150 pg/ml in no hormone. In separately cultured stromal cells, administration of HGF induces the expression of TGF receptor 1 in both hormonal conditions, but induction of TGF receptor 2 is only manifest in the P4-dominant condition. Administration of TGF-$\beta$ and HGF directly induce the decidualization marker prolactin mRNA in separately cultured stromal cells. Conclusion: It is likely that steroid hormones induces prolactin mRNA indirectly by promoting the cell to cell communication between the stromal and the epithelial cells. TGF-$\beta$ and HGF are two possible paracrine mediators in the human endometrial decidualization.

• International Journal of Automotive Technology
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• 제6권4호
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• pp.367-374
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• 2005

This paper proposes a sound quality index to evaluate the vehicle interior noise. The index was developed using a correlation analysis of an objective measurement and a subjective evaluation data. First, the objective set of measurements was obtained at two specified driving conditions. One is from a wide-open test condition and the other is from a constant-speed test condition. At the same time, subjective evaluation was carried out using a score of ten scale where 17 test engineers participated in the experiment. The correlation analysis between the psycho-acoustic parameters derived from the objective measurement and the subjective evaluation was performed. The most critical factors at both test conditions were determined, and the corresponding equations for the sound quality were obtained from the multiple factor regression method. Finally, a comparative work between previous index and present index was performed to validate the effectiveness of the proposed index.

• 한국패류학회지
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• 제30권2호
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• pp.107-116
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• 2014

북한강에 서식하고 있는 엷은재첩의 산란생태를 파악하기 위하여, 생식소 발달단계에 따른 생식주기, 군성숙도, 난경의 월별변화를 조사하였다. 각장에 대한 각고, 각폭, 전중, 육중간 의 상대성장식에서 상관계수 ($R^2$) 는 0.921-0.984로 높은 상관관계를 나타내었다. 엷은재첩은 기수재첩 보다는 소형종이었으며, 동시자웅동체로서 체내에서 수정되어 아가미 보육낭에서 부화되어 체외로 방출하는 난태생종이었다. 월별 비만도는 0.14-0.21 범위로 동계인 12월-2월에 낮은 값을 보이다가 2월부터 서서히 높아지기 시작하여 5월에 0.21로 정점을 보였다. 월별 육중량비는 25.9-38.7%로 비만도의 월별 변화와 같은 경향을 나타내었다. 비만도와 육중량비의 정점이 생식세포의 최성숙기와 1-2개월 차이가 있었다. 생식소의 조직상, 비만도 및 생식세포의 월별 변화를 종합하면 북한강산 엷은재첩 생식년주기는 분열증식기(12-2월), 성장기(2-5월), 성숙기(6-8월), 완숙 및 발생기(8-11월), 회복기(11-12월) 로 구분되어 하계산란종이었다. 군성숙 각장은 12.6 mm 였으며, 16 mm 이상의 개체는 모두 성숙하여 아가미에 보육낭을 형성하였다.