• 한국식품조리과학회지
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• 제32권5호
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• pp.575-584
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• 2016

Purpose: Nurungji is a traditional Korean food made by yellowish scorched rice. After getting gelatinization of rice, a thin crust of scorched rice will usually be left in the bottom of the traditional cooking pot. In this study, physicochemical characteristics and antioxidant properties of five commercial nurungji products (CNP1, CNP2, CNP3, CNP4, and CNP5) were evaluated. Methods: Physicochemical properties of the five commercial nurungji products were evaluated with AOAC method. The antioxidant activities were assessed using the 1,1-diphenyl-2-picryl hydrazyl (DPPH), 2,2-azinobis-(3-ethyl-benozothia zoline-6-sulfonic acid)(ABTS), ferric reducing antioxidant power (FRAP), and reducing power assays. Results: Water content was the highest in CNP3, followed by CNP1, CNP2, CNP5, and CNP4. Crude ash content of all nurungji was less than 1%. In Hunter color parameter, the significantly highest a value (redness) and b value (yellowness) were measured in the CNP4 product, meanwhile the lowest in CNP3 (p<0.05). The nurungji products of CNP4 and CNP5 had the significantly higher content in total polyphenols and total flavonoids, compared to those of other products. CNP3 and CNP2 had the lowest in total polyphenols and total flavonoids, respectively. CNP4 and CNP5 products showed the significantly higher values in antioxidant activities, whereas CNP3 had the lowest activity. Conclusion: The high value of antioxidant activities in CNP4 and CNP5 might have been affected primarily by the total polyphenols with increasing browning color during the heat treatment.

• 한국식품영양과학회지
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• 제37권5호
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• pp.618-624
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• 2008

브로일러에서 계피의 첨가급여가 브로일러의 성장능력, 혈액지질, 도체특성, 닭고기의 품질특성 및 계피맛, 향과 관련한 닭고기의 맛에 미치는 영향을 연구하였다. 병아리는 CNP를 함유하지 않은 대조구, CNP 2.0%, CNP 3.0%, CNP 4.0% 및 CNP 5.0% 첨가구로 구분하였다. 브로일러의 사료섭취량, 사료효율은 대조구와 비교할 때 처리구간 차이가 없었으나 체중은 CNP 3% 이상으로 첨가수준이 증가함에 따라서 유의적인 개선을 나타냈다(p<0.05). 혈액의 중성지방, HDL-C는 대조구에 비해서 CNP 첨가수준이 높아질수록 증가하는 경향을 나타냈으나, 총 콜레스테롤, LDL-C는 뚜렷하게 감소하였으며 각 처리구간 통계적 유의차가 있었다(p<0.05). 도체율은 CNP 첨가구가 대조구에 비해서 높았고, 닭 다리살은 CNP 3.0% 이상에서 증가하였으며, 닭 가슴살은 CNP 2.0%와 4.0% 첨가구가 높은 경향이었다(p<0.05). 닭 가슴살의 pH는 대조구와 비교하여 유의차가 없었으나, 보수력은 CNP 4% 이상 첨가수준이 높아질수록 증가하였고, TBARS는 CNP 3% 이상 첨가수준이 높아질수록 유의적으로 낮아졌다(p<0.05). 닭 가슴살의 육색은 CNP 첨가수준이 3% 이상 증가할수록 대조구에 비해서 더욱 밝은 색을 나타냈다(p<0.05). 닭 다리살 튀김과 삶은 닭 가슴살에서 계피와 관련한 맛, 향에 대한 관능평가 성적은 대조구와 비교할 때 CNP 첨가수준이 높아질수록 유의적으로 높게 나타났다(p<0.05). 본 실험에서 나타난 중요한 점은 브로일러 사료에 계피를 첨가 급여해줌으로써 닭고기의 도체특성과 맛을 개선할 수 있다는 사실이었다.

• Molecules and Cells
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• 제25권4호
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• pp.566-571
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• 2008

Calcineurin (Cn) is a calcium/calmodulin-dependent serine/threonine protein phosphatase that has diverse functions in different cell types and organisms. We screened proteins interacting with the C. elegans CnA homolog, TAX-6, by the yeast two-hybrid system. CNP-3 (Calcineurin interacting protein-3) is a novel protein that physically interacts with the catalytic domain of TAX-6. It is strongly expressed in the nuclei of intestine, hypodermis, dorsal uterine regions and spermatheca. Expression begins around the 60-cell stage and proceeds during all larval stages and the adult. To elucidate the biological function of cnp-3 we isolated a cnp-3 deletion mutant. Since CNP-3 binds CnA, we looked at factors associated with calcineurin loss-of-function mutants, such as brood size, body size, serotonin- and levamisole-mediated egg-laying behavior. The cnp-3(jh145) single mutant had no gross defects compared to wild-type animal. However, the phenotypes of the double mutants, tax-6(p675);cnp-3(jh145) and cnb-1(jh103);cnp-3(jh145), were more severe in terms of brood size, body size and serotonin-mediated egg-laying defects than tax-6(p675) and cnb-1(jh103), respectively. These results suggest that dysfunction of cnp-3 enhances certain calcineurin loss-of-function phenotypes in C. elegans.

• 국제초고층학회논문집
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• 제11권3호
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• pp.221-226
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• 2022

Installation of Structural Health Monitoring (SHM) system is a legal obligation for high-rise buildings over 200 m or 50-floor high in South Korea. CNP Dongyang has developed key technologies for SHM system design, installation, and data analyzing. Also, CNP Dongyang has applied SHM technology to a plenty of South Korea's representative high-rise buildings. The SHM technology, also, could be used in safety management of construction phase, evaluation of structural performance, etc. In this paper, state of the art SHM technologies and their application examples are introduced to give insight for future research and practical use of SHM.

• 마이크로전자및패키징학회지
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• 제23권4호
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• pp.69-77
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• 2016

We propose nano-scale Cu direct bonding technology using ultra-high density Cu nano-pillar (CNP) with for high stacking yield exascale 2.5D/3D integration. We clarified the joining mechanism of nano-scale Cu direct bonding using CNP. Nano-scale Cu pillar easily bond with Cu electrode by re-crystallization of CNP due to the solid phase diffusion and by morphology change of CNP to minimize interfacial energy at relatively lower temperature and pressure compared to conventional micro-scale Cu direct bonding. We confirmed for the first time that 4.3 million electrodes per die are successfully connected in series with the joining yield of 100%. The joining resistance of CNP bundle with $80{\mu}m$ height is around 30 m for each pair of $10{\mu}m$ dia. electrode. Capacitance value of CNP bundle with $3{\mu}m$ length and $80{\mu}m$ height is around 0.6fF. Eye-diagram pattern shows no degradation even at 10Gbps data rate after the lamination of anisotropic conductive film.

• 한국표면공학회지
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• 제51권3호
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• pp.179-184
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• 2018

In this study, Ni and tungsten carbide (WC) nanoparticles are simultaneously synthesized with the mesoporous carbon nanoparticles (CNP) using a solution plasma processing (SPP) in the benzene. The Ni and WC nanoparticles were formed through the sputtering effect of electrodes during discharge, and mean time CNP were formed through reduction reaction. TEM observation showed that loaded Ni and WC nanoparticles were evenly dispersed on the CNP. The results of electrochemical analysis demonstrated that an introduction of Ni nanoparticles promoted to improve catalytic activity for oxygen reduction reaction (ORR). Moreover, Ni-WC/CNP lead to fast electron transfer process compared to that of WC/CNP. Therefore, the inexpensive Ni-WC/CNP might be a promising as catalytic material for cathodes in fuel cell applications.

• 한국잡초학회지
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• 제2권2호
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• pp.141-145
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• 1982

IAA의 종자침지처리(種子浸漬處理)에 의하여 수도(水稻)에 대한 CNP와 Butachlor의 약해(藥害)를 경감(輕減)시킬 수 있는 가능성(可能性)을 검토(檢討)하기 위하여 담수직파(湛水直播)와 건답직파조건(乾畓直播條件)에서 기초실험(基礎實驗)을 수행(遂行)하였다. 1. 담수직파조건(湛水直播條件)에서 IAA 0.1, 1.0, 10.0ppm 에 수도종자(水稻種子)를 침지처리(浸漬處理)하므로써 CNP와 Butachlor에 의한 수도피해(水稻被害)의 경감효과(輕減効果)가 나타남에 따라 수도(水稻)의 초장(草長) 및 건물중(乾物重)은 IAA 무처리(無處理)에 비하여 현저히 증가(增加)되었다. 2. 건답직파조건(乾畓直播條件)에서는 IAA 0.1, 1.0ppm에 수도종자(水稻種子)를 침지처리(浸漬處理)하므로써 수도(水稻)에 대한 CNP와 Butachlor의 피해(被害)는 크게 경감(輕減)되었다. 3. 담수조건(湛水條件)에서 Butachlor를 처리(處理)하거나 건답직파조건(乾畓直播條件)에서 CNP를 처리(處理)한 경우에 IAA의 약해경감효과(藥害輕減効果)는 더욱 현저한 경향(傾向)이었다.

• 영재교육연구
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• 제20권3호
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• pp.847-866
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• 2010

창의성은 다양한 사고, 실험 수업, 열린 상황 등의 여러 조건과 체계적인 교육프로그램으로 신장시킬 수 있다. 이 연구에서는 과학영재의 창의성 신장 프로그램으로 CNP 모형을 개발하였다. 이 모형은 문제발견, 문제구체화, 문제해결 능력 영역을 강조하며, 과학적 문제발견, 통합적 탐구 기능과 탐구적 과학글쓰기를 포함한다. 개발된 6단계의 CNP 모형을 적용하기 위해 수업지도안과 학생 활동지를 별도로 개발하였다. K 대학교 과학영재 교육원 학생들에게 이 모형을 적용한 결과, 학생들은 독창성과 유창성이 향상되었고, 창의적으로 문제를 해결하였다. 또한 각 단계에서 창의적 문제발견 및 문제구체화, 문제해결 능력이 신장되었다. 이에 개발된 CNP 모형은 과학영재의 창의성 신장에 효과적임을 알 수 있었다.

• The Korean Journal of Physiology and Pharmacology
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• 제28권3호
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• pp.253-264
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• 2024

Chronic neuropathic pain (CNP) is a complex condition often arising from neural maladaptation after nerve injury. Understanding CNP complications involves the intricate interplay between brain-heart dynamics, assessed through quantitative electroencephalogram (qEEG) and heart rate variability (HRV). However, insights into their interaction in chronic pain are limited. Resting EEG and simultaneous electrocardiogram (lead II) of the participants were recorded for qEEG and HRV analysis. Correlations between HRV and qEEG parameters were calculated and compared with age, sex, and body mass index (BMI)-matched controls. CNP patients showed reduced HRV and significant increases in qEEG power spectral densities within delta, theta, and beta frequency ranges. A positive correlation was found between low frequency/high frequency (LF/HF) ratio in HRV analysis and theta, alpha, and beta frequency bands in qEEG among CNP patients. However, no significant correlation was observed between parasympathetic indices and theta, beta bands in qEEG within CNP group, unlike age, sex, and BMI-matched healthy controls. CNP patients display significant HRV reductions and distinctive qEEG patterns. While healthy controls exhibit significant correlations between parasympathetic HRV parameters and qEEG spectral densities, these relationships are diminished or absent in CNP individuals. LF/HF ratio, reflecting sympathovagal balance, correlates significantly with qEEG frequency bands (theta, alpha, beta), illuminating autonomic dysregulation in CNP. These findings emphasize the intricate brain-heart interplay in chronic pain, warranting further exploration.

• 생명과학회지
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• 제11권4호
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• pp.346-353
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• 2001

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) a prototype of the highly toxid halogenated arylhydrocarbons, bioaccumulates in the food chain and induces a complex spectrum of pathological responses. However, its effect on the nerve system is relatively not well studied. In this study we evaluated TCDDs cytotoxicity on the cortical cell and investigated its effect on the expression 2,3-cyclic nucleotide 3-phosphodiesterase(CNPase), a marker for oilgodendrocytes, The survival rates of 4 DIV cortical cells, that are dissociated from E18 rat cortex and maintained in the presence of TCDD, were 88.8, 83.6, 78.5, and 78.6%(5,10, 20 and 50 nM, respectively) where the reduction in 20 and 50mM TCDD were statistically very significant(p<0.01). Imunocytochemistry of cultured cells revealed that the intensities of immunostaining with an anti-CNP1&2 antibody depended on the concentrations of the toxin. Immunoblot analysis also showed differential expression of CNP1 and CNP2 in the presence of TCDD; the CNP1 expression was dose-dependently decreased. Interestingly, the expression of CNP2 in the presence if TDCC; the CNP1 expression was dose-dependently decreased. Interestingly, the expression of CNP2 fluctuated with the TCDD concentration. These results indicated that CNP1 and 2 are differentially regulated by TCDD, implying the functions of oligodendrocytes are modulated by the toxin.