• Title/Summary/Keyword: CNP-3

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The Physicochemical Characteristics and Antioxidant Properties of Commercial Nurungji Products in Korea (국내 시판 누룽지의 물리화학적 특성 및 항산화 성질 연구)

  • Yang, Ji-won;Choi, Il Sook
    • Korean journal of food and cookery science
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    • v.32 no.5
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    • pp.575-584
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    • 2016
  • Purpose: Nurungji is a traditional Korean food made by yellowish scorched rice. After getting gelatinization of rice, a thin crust of scorched rice will usually be left in the bottom of the traditional cooking pot. In this study, physicochemical characteristics and antioxidant properties of five commercial nurungji products (CNP1, CNP2, CNP3, CNP4, and CNP5) were evaluated. Methods: Physicochemical properties of the five commercial nurungji products were evaluated with AOAC method. The antioxidant activities were assessed using the 1,1-diphenyl-2-picryl hydrazyl (DPPH), 2,2-azinobis-(3-ethyl-benozothia zoline-6-sulfonic acid)(ABTS), ferric reducing antioxidant power (FRAP), and reducing power assays. Results: Water content was the highest in CNP3, followed by CNP1, CNP2, CNP5, and CNP4. Crude ash content of all nurungji was less than 1%. In Hunter color parameter, the significantly highest a value (redness) and b value (yellowness) were measured in the CNP4 product, meanwhile the lowest in CNP3 (p<0.05). The nurungji products of CNP4 and CNP5 had the significantly higher content in total polyphenols and total flavonoids, compared to those of other products. CNP3 and CNP2 had the lowest in total polyphenols and total flavonoids, respectively. CNP4 and CNP5 products showed the significantly higher values in antioxidant activities, whereas CNP3 had the lowest activity. Conclusion: The high value of antioxidant activities in CNP4 and CNP5 might have been affected primarily by the total polyphenols with increasing browning color during the heat treatment.

Effect of Dietary Cinnamon Powder on Savor and Quality of Chicken Meat in Broiler Chickens (닭고기의 품질 및 맛에 관한 계피 급여효과)

  • Park, Byung-Sung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.5
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    • pp.618-624
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    • 2008
  • A 35-day trial was carried out to determine the influence of dietary cinnamon powder (CNP) on the sensory evaluation and quality of chicken meat, carcass characteristics, plasma lipid level and growth performance of broiler chickens. There were 5 treatment groups: control; CNP 2.0%; CNP 3.0%; CNP 4.0%; and CNP 5.0%. The body weight of the broilers fed the diets containing 3.0% CNP was higher than the broilers fed the control feeds (p<0.05). The concentration of triacylglyceride, HDL-C was higher in the plasma from broiler chickens fed diets with CNP (p<0.05) but the concentrations of total cholesterol and LDL-C were significantly lower (p<0.05) compared to the control group. The carcass percentage, chicken breast and thigh weight were not different between the CNP and control groups. The WHC was significantly higher in the chickens fed 4% CNP diet, while the TBARS was significantly lower (p<0.05) in the chickens fed 3% CNP diet compared to the control group. The color of the breast muscle from the chickens fed 3% CNP diet was lighter than those from the control groups (p<0.05). The sensory evaluation of the taste and savor related to CNP in fried or boiled chicken meat were significantly better from the broiler chicken fed diets containing CNP than the control group (p<0.05). These results suggest that dietary cinnamon powder may improve savor and quality of chicken meat in broiler chickens.

A Novel Calcineurin-interacting Protein, CNP-3, Modulates Calcineurin Deficient Phenotypes in Caenorhabditis elegans

  • Kim, Yun Hee;Song, Hyun-Ok;Ko, Kyung Min;Singaravelu, Gunasekaran;Jee, Changhoon;Kang, Junsu;Ahnn, Joohong
    • Molecules and Cells
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    • v.25 no.4
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    • pp.566-571
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    • 2008
  • Calcineurin (Cn) is a calcium/calmodulin-dependent serine/threonine protein phosphatase that has diverse functions in different cell types and organisms. We screened proteins interacting with the C. elegans CnA homolog, TAX-6, by the yeast two-hybrid system. CNP-3 (Calcineurin interacting protein-3) is a novel protein that physically interacts with the catalytic domain of TAX-6. It is strongly expressed in the nuclei of intestine, hypodermis, dorsal uterine regions and spermatheca. Expression begins around the 60-cell stage and proceeds during all larval stages and the adult. To elucidate the biological function of cnp-3 we isolated a cnp-3 deletion mutant. Since CNP-3 binds CnA, we looked at factors associated with calcineurin loss-of-function mutants, such as brood size, body size, serotonin- and levamisole-mediated egg-laying behavior. The cnp-3(jh145) single mutant had no gross defects compared to wild-type animal. However, the phenotypes of the double mutants, tax-6(p675);cnp-3(jh145) and cnb-1(jh103);cnp-3(jh145), were more severe in terms of brood size, body size and serotonin-mediated egg-laying defects than tax-6(p675) and cnb-1(jh103), respectively. These results suggest that dysfunction of cnp-3 enhances certain calcineurin loss-of-function phenotypes in C. elegans.

Application of Strcutral Health Monitoring in Structual Engineering for Buildings

  • Ji Young, Kim;Hobeom, Song;Kanghyun, Park;Kwangryang, Chung
    • International Journal of High-Rise Buildings
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    • v.11 no.3
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    • pp.221-226
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    • 2022
  • Installation of Structural Health Monitoring (SHM) system is a legal obligation for high-rise buildings over 200 m or 50-floor high in South Korea. CNP Dongyang has developed key technologies for SHM system design, installation, and data analyzing. Also, CNP Dongyang has applied SHM technology to a plenty of South Korea's representative high-rise buildings. The SHM technology, also, could be used in safety management of construction phase, evaluation of structural performance, etc. In this paper, state of the art SHM technologies and their application examples are introduced to give insight for future research and practical use of SHM.

Nano-Scale Cu Direct Bonding Technology Using Ultra-High Density, Fine Size Cu Nano-Pillar (CNP) for Exascale 2.5D/3D Integrated System

  • Lee, Kang-Wook
    • Journal of the Microelectronics and Packaging Society
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    • v.23 no.4
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    • pp.69-77
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    • 2016
  • We propose nano-scale Cu direct bonding technology using ultra-high density Cu nano-pillar (CNP) with for high stacking yield exascale 2.5D/3D integration. We clarified the joining mechanism of nano-scale Cu direct bonding using CNP. Nano-scale Cu pillar easily bond with Cu electrode by re-crystallization of CNP due to the solid phase diffusion and by morphology change of CNP to minimize interfacial energy at relatively lower temperature and pressure compared to conventional micro-scale Cu direct bonding. We confirmed for the first time that 4.3 million electrodes per die are successfully connected in series with the joining yield of 100%. The joining resistance of CNP bundle with $80{\mu}m$ height is around 30 m for each pair of $10{\mu}m$ dia. electrode. Capacitance value of CNP bundle with $3{\mu}m$ length and $80{\mu}m$ height is around 0.6fF. Eye-diagram pattern shows no degradation even at 10Gbps data rate after the lamination of anisotropic conductive film.

One-pot Synthesis of Nickel and Tungsten Carbide Nanoparticles Supported Mesoporous Carbon Electrocatalyst for Oxygen Reduction Reaction (산소환원반응을 위한 니켈-텅스텐 카바이드 나노입자 담지 메조포러스 카본 촉매의 단일 합성 및 그 특성 평가)

  • Kim, Hyemin
    • Journal of the Korean institute of surface engineering
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    • v.51 no.3
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    • pp.179-184
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    • 2018
  • In this study, Ni and tungsten carbide (WC) nanoparticles are simultaneously synthesized with the mesoporous carbon nanoparticles (CNP) using a solution plasma processing (SPP) in the benzene. The Ni and WC nanoparticles were formed through the sputtering effect of electrodes during discharge, and mean time CNP were formed through reduction reaction. TEM observation showed that loaded Ni and WC nanoparticles were evenly dispersed on the CNP. The results of electrochemical analysis demonstrated that an introduction of Ni nanoparticles promoted to improve catalytic activity for oxygen reduction reaction (ORR). Moreover, Ni-WC/CNP lead to fast electron transfer process compared to that of WC/CNP. Therefore, the inexpensive Ni-WC/CNP might be a promising as catalytic material for cathodes in fuel cell applications.

Effects of IAA Seed Pretreatment on Reduction of CNP and Butachlor Injury to Rice (IAA의 종자침지처리(種子浸漬處理)가 CNP와 Butachlor에 의한 수도약해(水稻藥害)의 경감(輕減)에 미치는 영향)

  • Pyon, J.Y.;Kwon, Y.W.;Lee, E.W.
    • Korean Journal of Weed Science
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    • v.2 no.2
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    • pp.141-145
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    • 1982
  • In order to determine the possibility of reducing rice injury caused by CNP and butachlor application, the effects of IAA seed presoaking on CNP and butachlor action against early growth of rice seedlings were investigated under flooded direct-seeding and dry-seeded conditions. CNP and butachlor injury to rice was reduced by soaking rice seeds at 0.1, 1.0 and 10ppm of IAA solution for 36 hours before seeding under flooded condition and thus shoot length and dry weight of rice seedlings increased compared with those of IAA untreated seedlings. IAA seed pretreatment also overcame the inhibitory effect of CNP and butachlor under dry-seeded condition. Effect on reducing rice injury by IAA pretreatment was more remarkable when CNP applied under dry seeded condition and butachlor under flooded condition.

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Development And Application of CNP Model for the Enhancing Creativity of Scientifically Gifted Students (과학영재의 창의성 신장을 위한 CNP 모형의 개발과 적용)

  • Hwang, Yo-Han;Park, Jong-Seok
    • Journal of Gifted/Talented Education
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    • v.20 no.3
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    • pp.847-866
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    • 2010
  • Enhancing creativity is possible to offer systematic education programs and several conditions as variable thinking, experiment lesson, opened-situation. We developed CNP model as program for enhancing creativity. The CNP model emphasizes that parts of problem finding, embodying and solving ability and includes scientific problem finding tool, Integrated Process Skills and Science Writing Heuristic. The CNP Model is comprised of six step. We developed teachers' guide and student's worksheets for application. Result of applied CNP model to students of scientifically gifted education center in K University, students were able to enhanced originality and fluency and had solved problems by creative way. And creative problem finding, embodying and solving ability were increased. Therefore, the CNP model was effective in enhancing the creativity of scientifically gifted.

Relation between heart rate variability and spectral analysis of electroencephalogram in chronic neuropathic pain patients

  • John Rajan;Girwar Singh Gaur;Karthik Shanmugavel;Adinarayanan S
    • The Korean Journal of Physiology and Pharmacology
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    • v.28 no.3
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    • pp.253-264
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    • 2024
  • Chronic neuropathic pain (CNP) is a complex condition often arising from neural maladaptation after nerve injury. Understanding CNP complications involves the intricate interplay between brain-heart dynamics, assessed through quantitative electroencephalogram (qEEG) and heart rate variability (HRV). However, insights into their interaction in chronic pain are limited. Resting EEG and simultaneous electrocardiogram (lead II) of the participants were recorded for qEEG and HRV analysis. Correlations between HRV and qEEG parameters were calculated and compared with age, sex, and body mass index (BMI)-matched controls. CNP patients showed reduced HRV and significant increases in qEEG power spectral densities within delta, theta, and beta frequency ranges. A positive correlation was found between low frequency/high frequency (LF/HF) ratio in HRV analysis and theta, alpha, and beta frequency bands in qEEG among CNP patients. However, no significant correlation was observed between parasympathetic indices and theta, beta bands in qEEG within CNP group, unlike age, sex, and BMI-matched healthy controls. CNP patients display significant HRV reductions and distinctive qEEG patterns. While healthy controls exhibit significant correlations between parasympathetic HRV parameters and qEEG spectral densities, these relationships are diminished or absent in CNP individuals. LF/HF ratio, reflecting sympathovagal balance, correlates significantly with qEEG frequency bands (theta, alpha, beta), illuminating autonomic dysregulation in CNP. These findings emphasize the intricate brain-heart interplay in chronic pain, warranting further exploration.

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the expression of 2',3'-cyclic nucleotide 3'-phosphodiesterase(CNPase) in rat cortical neurons in culture (배양한 흰주 대뇌세포에서 2,3,7,8-tetrachlorodibenzo-p-dioxin 이 2',3'-cyclic nucleotide 3'-phosphodiesterase(CNPase)의 표현에 미치는 영향)

  • Cho, Sun-Jung;Jung, Jae-Seob;Kim, Deock-Kyu;Shin, Seung-Chul;Go, Ok;Jung, Yong-Wook;Ko, Bok-Hyun;Jin, Ing-Nyol;Moon, Il-Soo
    • Journal of Life Science
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    • v.11 no.4
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    • pp.346-353
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    • 2001
  • 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) a prototype of the highly toxid halogenated arylhydrocarbons, bioaccumulates in the food chain and induces a complex spectrum of pathological responses. However, its effect on the nerve system is relatively not well studied. In this study we evaluated TCDDs cytotoxicity on the cortical cell and investigated its effect on the expression 2,3-cyclic nucleotide 3-phosphodiesterase(CNPase), a marker for oilgodendrocytes, The survival rates of 4 DIV cortical cells, that are dissociated from E18 rat cortex and maintained in the presence of TCDD, were 88.8, 83.6, 78.5, and 78.6%(5,10, 20 and 50 nM, respectively) where the reduction in 20 and 50mM TCDD were statistically very significant(p<0.01). Imunocytochemistry of cultured cells revealed that the intensities of immunostaining with an anti-CNP1&2 antibody depended on the concentrations of the toxin. Immunoblot analysis also showed differential expression of CNP1 and CNP2 in the presence of TCDD; the CNP1 expression was dose-dependently decreased. Interestingly, the expression of CNP2 in the presence if TDCC; the CNP1 expression was dose-dependently decreased. Interestingly, the expression of CNP2 fluctuated with the TCDD concentration. These results indicated that CNP1 and 2 are differentially regulated by TCDD, implying the functions of oligodendrocytes are modulated by the toxin.

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