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A Review of Recent Oriental Medicine Studies on Female Sexual Dysfunction (여성 성기능장애 관련 최근 국내외 한의학 연구 동향에 대한 고찰)

  • Choi, Min-Sun;Kim, Dong-Il
    • The Journal of Korean Obstetrics and Gynecology
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    • v.24 no.3
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    • pp.171-189
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    • 2011
  • Objectives: Female Sexual Dysfuction(FSD) is a common gynecologic condition and its prevalence is more higher than men. Despite its high prevalence and clinical importance, research on FSD is not enough in both of oriental and western medicine. The purpose of this study is to review research tendency of recent oriental medicine studies on FSD and to suggest the following research on FSD. Methods: We searched oriental medicine papers related to FSD published in the last 10 years(2001-2011) through Korean Medicine Gynecology Society database, KISS, RISS, NDSL, CNKI(China National Knowledge Infrastructure), and Pubmed. Results: 26 papers were searched, then 18 papers of them were related to Traditional Chinese Medicine(TCM), 8 papers of them were related to Korean Medicine(KM). In classification according to paper type, 16 papers were clinical study, 1 paper was experimental study, 2 papers were bibliographic study, and 7 papers were the other study. Then 5 papers of clinical study was Randomized Controlled Trial(RCT). Conclusion: There was a lack of oriental medicine research on FSD. On the base of this study, so further research is needed. Especially, Clinical trials such as RCT have strong objective evidence power in the viewpoint of Evidence Based Medicine(EBM) are needed.

Recent Clinical Research Trends on Acupuncture Treatment of Meniere's Disease (메니에르 병의 침 치료에 관한 최근 임상 연구 동향)

  • Lee, Kyou-Young;Hong, Chul-Hee
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.31 no.3
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    • pp.26-38
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    • 2018
  • Objectives : The purpose of this study is to investigate the possibility of applying acupuncture to the treatment of meniere's disease, which has no definite treatment methods, by analyzing the latest clinical researches about acupuncture treatment of meniere's disease. Methods : A case study and Randomized Controlled Trial (RCT) related to the acupuncture treatment of meniere's disease were searched using domestic and international thesis search engines including OASIS, CNKI, J-STAGE, PubMed. This study include acupuncture treatment and acupuncture combined with other treatments such as herbal medicine. The search was limitied to the publication date from 2000 to 2018 with free full text. Results : 17 cases were selected. There were 7 case studies in Korea, 5 case studies in China, and 5 RCT papers in China. All 12 cases reported improvement in meniere's disease and all RCT studies showed significantly higher treatment effects in the experimental group than in the control group. Conclusions : Acupuncture treatment showed significant effects for meniere's disease when applied alone or in combination with other treatments. In the future, various systematic studies should be conducted only for acupuncture treatment.

Efficacy of Herbal Medicines for the Treatment of Seborrheic Dermatitis : Systematic Review (지루성 피부염의 한약 치료 효과에 대한 체계적 문헌고찰)

  • Kim, Jeong-Yoon;Jang, Young-Woo;Kim, Hye-Gyeong;Lim, Seung-Hwan
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.31 no.3
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    • pp.67-83
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    • 2018
  • 목적 : 체계적 문헌고찰을 통하여 지루피부염에 한약복용의 효과와 연구의 질을 평가하기 위함. 방법 : OASIS, NDSL, EMBASE, Pubmed, Cochrane Library, CINAHL, CNKI, WANFANG, CiNii, J-STAGE를 이용하여 검색하였다. 검색은 2018년 6월 21일에 시행되었으며 P는 지루성 피부염, I는 한약 복용으로 진행하였다. 두 명의 연구자가 독립적으로 연구를 평가하고 선정하였으며, 의견이 다를 경우 제 3자가 개입하여 다수결로 결정하였다. 결과 : 중복 검색을 제외하고 총 952개의 연구가 검색되었으며 제목과 초록을 검토한 결과 897개의 연구가 제외되었다. 나머지 55개 연구의 전문을 검토한 결과 4개의 RCT연구가 최종 선정되었다. 선정된 연구는 발행연도, 대상, 중재법, 평가방법, 효과, 부작용, RoB를 통해 평가하였다. 한약 복용을 한 치료군에서 대조군에 비해 유의하게 호전을 보였으며 중대한 부작용은 없었다. 결론 : 지루성 피부염에 있어 한약 복용은 효과적이며 안전성이 있는 하나의 치료법이다. 향후 다양하고 체계적인 RCT의 시행이 요구된다.

A Review of Research on the Treatment of Peroneal Nerve Palsy by Acupuncture and Moxibustion

  • Ryu, Hwa Yeon;Lee, Hyun;Yoon, Kwang Sik;Oh, Seo Young;Kong, Hae Jin;Kang, Jae Hui
    • Journal of Acupuncture Research
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    • v.35 no.2
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    • pp.52-60
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    • 2018
  • Background: This was a retrospective review of published articles reporting acupuncture and moxibustion treatment of peroneal nerve palsy. Methods: On-line database searches were carried out using; Cochrane Library, Pubmed, CNKI, NDSL and OASIS to find articles reporting acupuncture and moxibustion treatment for peroneal nerve palsy. Duplicate articles and studies that were not relevant to the topic were excluded, along with review articles and commentaries. Results: 20 studies were selected, 18 clinical case studies (47 patients) and 2 randomized controlled trials (154 patients). Intervention treatments included acupuncture, moxibustion, bee-venom (BV), pharmacopuncture, electroacupuncture and acupotomy. Surprisingly, although peroneal nerve palsy is not a very rare disease, only 2 studies out of 20 carried out a randomized controlled trial. Conclusion: Although studies to date report the efficacy of acupuncture and moxibustion treatment in peroneal nerve palsy patients, the absence of objective evaluation and the absence in the reporting of side-effects remains an issue.

The XRCC1 Arg280His Gene Polymorphism and Hepatocellular Carcinoma Risk: A Meta-analysis

  • Li, Lu-Ping;Wu, Wei;Li, Xing-Hai;Song, Shu-Sen
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.3
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    • pp.2033-2036
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    • 2013
  • Many studies have suggested that the XRCC1 Arg280His gene polymorphism might be involved in the development of hepatocellular carcinoma (HCC). However, the results have been inconsistent. In this study, the authors performed a meta-analysis to assess the association between XRCC1 Arg280His and HCC susceptibility. Published literature from PubMed, EMBASE and CNKI Data was searched. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using fixed- or random-effects models when appropriate. Begg's test was used to measure publication bias. A total of 7 case-control studies covering 1,448 HCC cases and 1,544 controls were included. No significant variation in HCC risk was detected in any of the genetic models overall. In the stratified analysis, four studies with sample sizes over 300 produced similar results. The corresponding pooled ORs were not substantially altered after the exclusion of three studies deviating from Hardy-Weinberg equilibrium in the control group, which indicated reliability for our meta-analysis results.

Traditional Chinese Medicine in treatment of Tic disorder (소아(小兒) 틱장애에 대한 최근(最近) 치료(治療) 동향(動向))

  • Lee, Iyun-Shil;Yoon, Ji-Yeon;Han, Jae-Kyung;Kim, Yun-Hee
    • Journal of Haehwa Medicine
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    • v.22 no.1
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    • pp.91-104
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    • 2013
  • Objective : This study was designed to analyze the clinical studies on Tic disorder in traditional Korean medicine and traditional Chinese medicine. Methods : To figure out the Tic disorder, Korean medical studies from Oriental Medicine Advanced Searching Integrated System (OASIS) and Chinese Medical Journals from Wangfang data and China National Knowledge Infrastructure (CNKI) which published in 2008 to 2012 were analyzed. Results & Conclusions : 1. DSM-IV(7 studies), CCMD(3 studies) were frequently used in the diagnosis of tic disorder. 2. The herbs used for the treatment of tic disorder are Uncariae ramulus et Uncus(釣鉤藤), Paeoniae Radix Alba(白芍藥), Poria(白茯苓), Buthus martensi Karsch(全蝎) etc. 3. Acupuncture points frequently used were Paek'oe(GV20), Pungji(GB20), Naegwan(PC6), Sasinchong(EX-HN1), T'aech'ung(LR3), Joksamni(ST36), Hapgok(LI4) and so on. 4. The cause of Tic disorder is connected with liver, heart, spleen, kidney, gall bladder among the internal organs and Fire(火), Wind(風), Dampness(濕) of external causes.

Review of Clinical Studies for Oriental Treatment of Autism in Traditional Chinese Medicine (자폐증 한방 치료에 대한 최신 임상 연구 고찰 - 중의학 논문 중심으로 -)

  • Lee, Jin Hwa;Han, Jae Kyung;Lee, Hye Lim;Kim, Yun Hee
    • The Journal of Pediatrics of Korean Medicine
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    • v.28 no.4
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    • pp.85-95
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    • 2014
  • Objectives The purpose of this review is to investigate the clinical studies of oriental treatment for Autism in China and seek the better methods to study and treat Autism in Korea. Methods We searched for the study at CNKI by keywords, 'Autism', '孤獨症', '自閉症', in the last 5years. Results Selected 14 clinical studies were divided into 6 case reports and 8 control studies. The subjects of clinical study were the average 4-9 years old children. It was described that the symptoms were improved after treatment in 6 case reports. 8 control studies reported that the experimental group were better effective than the comparison group. Frequently used method for treatment was Scalp acupuncture. Conclusions It is promising that we could develop our own treatment and studies for autism in Korea by using Scalp acupuncture, based on these clinical studies.

Trends of Tuina Therapy on Depression and Its Efficacy -based on CNKI-

  • Kwon, Chan-Young;Choi, Eun-Ji;Kim, Jong-Woo;Chung, Sun-Young
    • Journal of Oriental Neuropsychiatry
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    • v.26 no.3
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    • pp.251-266
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    • 2015
  • Objectives: The purpose of this study is to investigate the research about using tuina therapy for depression and to determine its efficacy. Methods: All relevant articles were searched in the China National Knowledge Infrastructure using the terms 'tuina' and 'depression'. Results: Forty-one studies were selected, 34 randomized controlled trials (RCTs) and 7 prospective studies. The Chinese Classification of Mental Disorders and Hamilton Depression Rating Scale were used most frequently as diagnostic criteria and an assessment tool, respectively. Conduction exercise therapy was used in all studies; in contrast, Zheng Xing exercise therapy was used in only 1 study of depression patients with neck vertebrae disease. In 9 RCTs that showed scores of more than 2 points on a modified Jadad scale, tuina therapy had significant antidepressant efficacy compared with conventional treatment. However, more high-quality studies are required. Conclusions: Tuina therapy has a valid therapeutic effect on depression according to studies published in China; if evidence accumulates from high-quality studies, it can be considered a non-pharmacologic treatment for depression in Korean medicine, as well.

An Effect of Yoga Therapy on Relieving Dysmenorrhea ; RCTs(Randomized controlled trials) Review (요가 요법이 월경통 증상 완화에 미치는 효과 고찰)

  • Park, Ki-On;Hwang, Eui-Hyoung;Sul, Jae-Uk;Shin, Mi-Suk
    • Journal of Society of Preventive Korean Medicine
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    • v.15 no.2
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    • pp.39-49
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    • 2011
  • Objectives : This study is to explain the effects of Yoga therapy for relieving dysmenorrhea on the aspect of Oriental Medicine and to identify the therapeutic Yoga asanas applicable to clinic medicine. Methods : We searched papers using Pubmed, CNKI and 7 Korean medical databases. We used "Yoga" and "Dysmenorrhea" as keyword. Limitations were as follows ; the last 20 years of publications and search range only including RCTs. Papers without inclusion criteria were excluded. We classified all the searched RCTs studies into Yoga exercise prescriptions. Results : A total of 47 studies were found. And 38 were excluded during extract screening. Finally 3 RCTs were selected and analyzed out of 9 papers. Blood sampling and survey questionnaires were used in the outcome measure. They reported that Yoga exercise could be used for dysmenorrhea patients, which has a curative effect. Conclusions : Yoga therapy can be explained as Meridian muscle theory in the concept of Oriental Medicine. Also, it may be a favorable choice for dysmenorrhea patients. Further studies to describe the effects of Yoga therapy will be needed more.

Allium Vegetables and Risk of Prostate Cancer: Evidence from 132,192 Subjects

  • Zhou, Xiao-Feng;Ding, Zhen-Shan;Liu, Nai-Bo
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.7
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    • pp.4131-4134
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    • 2013
  • Objective: To evaluate the relationship between allium vegetable intake and risk of prostate cancer. Methods: A systematic literature search up to May 2013 was carried out in PubMed, EMBASE, Scopus, Web of Science, Cochrane register, and Chinese National Knowledge Infrastructure (CNKI) databases, and the references of retrieved articles were also screened. The summary relative risks with 95% confidence interval for the highest versus the lowest intake of allium vegetables were calculated. Heterogeneity and publication bias were also evaluated. Results: A total of nine epidemiological studies consisting of six case-control and three prospective cohort studies were included. We found a significantly decreased risk of prostate cancer for intake of allium vegetables (OR=0.82, 95% CI 0.70, 0.97). Moreover, in the subgroup analysis stratified by allium vegetable types, significant associations were observed for garlic (OR=0.77, 95% CI 0.64-0.91) but not onions (OR=0.84, 95% CI 0.62-1.13). Conclusions: Allium vegetables, especially garlic intake, are related to decreased risk of prostate cancer. Because of the limited number of studies, further well-designed prospective studies are warranted to confirm the findings of our study.