• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.13 no.1
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• pp.253-266
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• 2000

In order to strengthen objectivity and availability of oriental herb medicine, the standard formula for herbs has been attempted to set up by experimenting and documentary testing original herbs which were recorded in authorized document. The object herb medicine is Codonopsis Pilosulae Radix. The internal and external morphological standard in this study is expected to supply the search for several physiochemical reaction, biological reaction, determination of indicator material and identification of gene with basic sources in the future. The result of study is as follows; In the external shape, it was possible that herbs were distinguished according to artificial classification and that same genus-degree of relatedness among herbs could be distinguished by more precise and active observation. In the shape of real herbs, I compared current herbs in market with original herbs which were just collected or were on the course of drying. In addition, it was possible that the internal shape could be identified by using microscope after butanol series. In powder herbs, it was possible to purify the shape by microscope through maceration of natural and powder herbs. Though it was impossible to make distinction of herbs which are not current in my search contents, this search contents will be a standard for alpplying herbs in the future. Despite such a useful character, it was difficult to deal with power herbs because it was uncertain to make a standard for them on account of the crush of these tissue. Since powders shape of herbs in a few documents were regard not as the powder shapes of natural herbs but as the maceration state of them. It is suggested that we should inspect the original herbs which are not crushed yet with a microscope in order to identify crushed shape of powder herbs from now on. An Additional standard establishment including physiochemical reaction and gene research is required in order to supplement the fault of this search. As for the supplement about this search, considering that many kinds of same genus-degree of relatedness are being current now, it is necessary that each herb should he collected only after identifying and that the succeeding search of each herb should be proceeded for the regular establishment of internal and external standard.

• Journal of Sasang Constitutional Medicine
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• v.27 no.3
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• pp.307-317
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• 2015

Objectives The purpose of study was to identify cancer related symptoms of Sasang Constitution based on the classic of Sasang Constitutional Medicine (SCM). Methods The bibliographical study was performed with "Dongyisoosebowon-Shinchukbon(東醫壽世保元 辛丑本)", Dongyisoosebowon-Sasangchobongwon(東醫壽世保元 四象草本券), "Cancer", and several review articles. The perspective on severe illness in SCM was investigated. And 'the critical state' of constitutional symptoms based on "Dongyisoosebowon" was identified as cancer related symptoms. Results and Conclusions The perspective on severe illness of SCM was focused on the human being itself, compared with symptom based traditional Chinese medicine. The preservation of requisite energy (保命之主) was a vital factor of longevity to maintain healthy status and the classification of severity of disease. And critical state was an important indicator to control severe illness. Regarding cancer related symptoms in SCM, Janggwol(臟厥), Eumsung-gyeokyang(陰盛隔陽證), Janggyeol(藏結證) of Soeumin symptoms, Hwangdal(黃疸), Haso(下消), Eumheo-oyel(陰虛午熱證), Gochang, Tohyul(吐血) of Soyangin's symptoms, Joyeol(燥熱證), Bokchang-bujong(腹脹浮腫) of Taeeumin's symptoms, and Eolgyek of Taeyangin's symptoms could be shown the association with cancer. According to the prognosis on disease severity, regimens of daily life, behavior modifications as well as medications were also emphasized with great importance to control severe illness in SCM. These holistic approach for controlling severe illness in SCM could lead to the improvement of treatment outcome.

• Proceedings of the Korean Geotechical Society Conference
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• 2002.03a
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• pp.237-244
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• 2002

Televiewer is a logging tool capable of scanning the borehole wall. The tool uses a rotating acoustic beam generator that acts as both a transmitter and receiver. The beams are sent toward the wall. The amplitude of a returning signal from the wall has nearly a linear relationship with the reflection coefficient R of the borehole wall, when the wall is smooth. As R depends only on rock impedance for fixed water impedance, the amplitude is directly associated with mass density and seismic velocity of rock. Meanwhile, the amplitude can be further reduced by wall roughness that may be caused by drilling procedures, differences in rock hardness, because the rough surface can easily scatter the acoustic energy and sometimes the hole becomes elongated in all directions according to the degree of weathering. In this sense, the amplitude is related to the hardness of rocks. For convenience of analysis, the measured amplitude image(2-D data(azimuth ${\times}$ depth)) is converted, with an appropriate algorithm, to the 1-D data(depth), where the amplitude image values along a predetermined fracture signature(sinusoid) are summed up and averaged. The resulting values are subsequently scaled simply by a scalar factor that is possibly consistent with a known strength. This scaled Televiewer reflectivity is named, as a matter of convenience,“Televiewer rock strength”. This paper shows, based on abundant representative case studies from about 8 years of Televiewer surveys, that Televiewer rock strength might be regarded, on a continuous basis with depth, as a quitely robust indicator of rock classification and in most cases as an approximate uniaxial strength that is comparable to the rebound value from Schmidt hammer test.

• Journal of Gastric Cancer
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• v.16 no.1
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• pp.21-27
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• 2016

Purpose: Transducer-like enhancer of split 1 (TLE1) is a member of the Groucho/TLE family of transcriptional co-repressors that regulate the transcriptional activity of numerous genes. TLE1 is involved in the tumorigenesis of various tumors. We investigated the prognostic significance of TLE1 expression and its association with clinicopathological parameters in gastric cancer (GC) patients. Materials and Methods: Immunohistochemical analysis of six tissue microarrays was performed to examine TLE1 expression using 291 surgically resected GC specimens from the Soonchunhyang University Cheonan Hospital between July 2006 and December 2009. Results: In the non-neoplastic gastric mucosa, TLE1 expression was negative. In GC, 121 patients (41.6%) were positive for TLE1. The expression of TLE1 was significantly associated with male gender (P=0.021), less frequent lymphatic (P=0.017) or perineural invasion (P=0.029), intestinal type according to the Lauren classification (P=0.024), good histologic grade (P<0.001), early pathologic T-stage (P=0.012), and early American Joint Committee on Cancer stage (P=0.022). In the Kaplan-Meier analysis, the TLE1 expression was significantly associated with longer disease-free (P=0.022) and overall (P=0.001) survival rates. Conclusions: We suggested that TLE1 expression is a good prognostic indicator in GCs.

• Korean Journal of Environmental Biology
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• v.25 no.2
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• pp.149-157
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• 2007

This study focused on patterning waterbirds occurrences at the western costal area of the Korean Peninsula in winter and relating the occurrence patterns with their environmental factors. Waterbird communities were monitored at 10 different study areas, and the composition of land cover as environmental factors was estimated at each study area. Overall dabbling ducks were the most abundant with 84% of total individuals, followed by shorebird and diving ducks. Species Anae platyrhynchos was the first dominant species, and Anas formosa was the second one. Self-organizing map (SOM), an unsupervised artificial neural network, was applied for patterning wintering waterbird communities, and identified 6 groups according to the differences of communities compositions. Each group reflected the differences of indicator species as well as their habitats.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.2
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• pp.304-314
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• 2005

The major concept of Sasang typology is that the disease susceptibility and drug response as well as physiological characteristics are presumed to be different depending on their Sasang types. Although characterizing fundamental basis of their traits are crucial in this research field, only pathological susceptibility and physical appearances were thoroughly studied. We evaluated their physiological characteristics by tapping psychological, physical and genetic traits of each Sasang types. After determining the Sasang type of one hundred three college students based on the Questionnaire for the Sasang Constitution Classification, the psychological, physical and genetic traits of each type were analyzed with the Myers-Briggs Type Indicator (MBTI), Bioelectrical Impedance Analysis and genetic polymorphism test, respectively. Each of the Sasang types showed significantly different profiles (Generalized estimation equation, coef=11.88, z=2.13, p=0.033), and could be distinctively classified based on their MBTI scores (discriminant analysis Wilks Lambda=0.611, df=8, chi-square=36.7, p<0.001). Subjects with the So-Eum type (Introversion and Judging) and the So-Yang type (Extroversion and Perceiving) showed contrasting psychological features, however they had similar anthropometric characteristics. Subjects with the Tae-Eum type showed bigger Body Mass Index ($R^2$=0.22, df=4, 74, F=5.07, p=0.001) and body shape compared to others. Although there were no significant differences in G-protein beta-3 subunit polymorphism, angiotensin-converting enzyme polymorphism and Methylenetetrahydrofolate reductase polymprhisms among groups with Sasang types, it was shown that the dopamine system could be one for genetic marker for Sasang typology. These results demonstrated distinctive and essential traits of Sasang typology using reproducible psychometric, anthropometric and genetic evaluations. We also found that the Sasang typology was a bio-psychological typology which could show trait-specific guideline for individualized medicine.

• Journal of Sasang Constitutional Medicine
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• v.33 no.3
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• pp.72-86
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• 2021

Objectives The aim of this study was to review the current clinical Sasang constitutions studies by using genetics and to provide basic data for developing in a better direction of research. Methods Research articles on genetics of the clinical Sasang constitutions studies were extracted from six databases. The articles were classified were published year, published journals, and the types of studies. Subjects of research and experimental methods for the genetic research were summarized. Results A total of 43 selected research articles were published from 1996 to 2020 and more than half of them were published in Journal of Sasang Constitutional Medicine and Journal of Korean Oriental Medicine. There were three main types of researches. The three types of researches were for investigating a genetic indicator for classification of Sasang constitutional type, confirming a relationship between pathological gene and Sasang constitutional type, and checking a hereditary of Sasang constitutional type. But these studies did not yield clear results illustrating a relationship between Genetics and Sasang Constitutional Medicine. Discussion In this study, the necessity of the follow up studies to demonstrate a relationship between Genetics and Sasang Constitutional Medicine was confirmed.

• The Journal of the Korea Contents Association
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• v.19 no.3
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• pp.261-274
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• 2019

This paper aims to develop an appropriate methodology for establishing an investment strategy for 'demonstration of artificial rainfall technology using UAV' and that include establishment of a technology classification, set of indicators for technology evaluation, suggestion of final key technology as a whole study area. It is designed to complement the latest research trend analysis results and expert committee opinions using quantitative analysis. The key indicators for technology evaluation consisted of three major items (activity, technology, marketability) and 10 detailed indicators. The AHP questionnaire was conducted to analyze the importance of indicators. As a result, it was analyzed that the attribute of the technology itself is most important, and the order of closeness to the implementation of the core function (centrality), feasibility (feasibility). Among the 16 technology groups, top investment priority groups were analyzed as ground seeding, artificial rainfall verification, spreading and diffusion of seeding material, artificial rainfall numerical modeling, and UAV sensor technology.

• Korean Journal of Environment and Ecology
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• v.33 no.1
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• pp.16-27
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• 2019

This study was identified the survey period and emergence of main species of dragonfly species, an indicator species that can identify the characteristics of wetland ecosystem. I surveyed the species and population of dragonflies once every two weeks from May 2015 to October 2016(29 times). From January to March, November and December were excluded from the cluster classification because the dragonflies were not observed. In April and October, the species was emerged but it was not suitable because it could not represent the time of the seasons. When we divide by month, it was able to judge from April to June as spring. Except the May, there were some changes due to rainfall and temperature, and sometimes June was included in the summer season. June, July and August correspond to summer, and September and October fall in Autumn. In June and October, the change was expected due to the effects of temperature and so it was judged as a partial fit. Looking at the change of the species, Coenagrion johansson and Paracercion calamorum were increase at the spring, and then Crocothemis servilia mariannae, Paracercion calamorum, Anax nigrofasciatus, Lyriothemis pachygastra, Orthetrum melania were abruptly enlarge in summer. At last, Sympetrum kunckeli, Lestes temporaris tended to be higher in Autumn.

• Korea Journal of Hospital Management
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• v.23 no.4
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• pp.53-64
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• 2018

Purposes: The hospitals needs to generate a minimum profit, in order to perform its own role such as providing high-quality medical services. The demand for hospital management is increasing, as the social demands are diversified and the financial transparency is emphasized. The purpose of this study is to compare hospitals management based on Dupont Identity, by various hospital classification. Methodology: This study is based on '2016 Statistics for Hospital Management' provided by the Korea Health Industry Development Institute. The hospitals were classified according to the scope of care, the type of establishment, the location, and the number of beds. We analyzed the general and financial characteristics of over 337 hospitals using the method of Dupont Identity. Findings: Net profit margin (PM) has the biggest impact on return of equity (ROE). By the number of beds, general hospital with 160-299 beds have the highest return on equity (ROE). By location, hospitals in local municipalities have higher return on equity than hospitals in urban municipalities. According to the type of establishment, public hospitals have lower business performance, and although they invest more than private hospitals. Practical Implications: This study can inspire interest and provide understanding in hospital management and financial structure, by analyzing through an intuitive indicator named Dupont identity. It is possible to provide basic data for hospital management methods for each financial elements, in order to increase the profitability of hospitals.