Background: Gastroenteropancreatic neuroendocrine tumors (GNs) are slow growing and although their incidence has increased in recent years, they are relatively rarely seen. Somatostatin analogues are used in the treatment of GNs that express somatostatin receptor (SR). We aimed to investigate the expression of SR2 and SR5 in GNs. Materials and Methods: In this study the expression of SR2 and SR5 was investigated immunohistochemically in 49 cases (26 males, 23 females) diagnosed and graded with GN according to the World Health Organization classification 2010. Results: The percentage of SR2 staining was 91.0% in grade 1, 82.8% in grade 2 and 100% in grade 3. On the other hand, the percentage of SR5 staining was 81.8% % in grade 1, 60.0% in grade 2 and 0% in grade 3. According to the tumor localization, the percentages of SR2 expression were as follows: pancreas 85.7%, stomach 100%, small bowel 70%, appendix 85.7% and rectum 100%. The percentages of SR5 expression were: pancreas 61,9%, stomach 37.5%, small bowel 70%, appendix 71.5% and rectum 66.6%. There was a significant negative correlation between ki67 percentage and SR5 expression (r=-0.341, p=0.016). Conclusions: In this study, GNs were found to highly express SR2 and SR5. Although the expression of SR2 and SR5 changed according to tumor localization, the expression of SR2 was higher than the expression of SR5 in GN. There was a significant negative correlation between ki67 and SR5. Accordingly, SR5 may be a prognostic indicator of GN.
Journal of Korean Academy of Nursing Administration
/
v.11
no.4
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pp.401-414
/
2005
Purpose: This study was to evaluate the utilization of health care service and to provide supportive data for health care policy making in one urban area in Korea. Method: This study tested the significance of public health service using the database of an university hospital and public health center from Feb. 2000 to Dec. 2004. Data were analyzed by multidimensional analysis and data mining technique and produced the information on the classification of utilization characteristics by main disease and the total cost of use and disease association with the users of the public health center. Results: The Results were as follows: 1) Top 10 diseases in the area accounted for 22.4% of total frequency for the most recent 5 years in university hospital, while 59.0% in public health center. 2) There were significant correlations between university hospital and public health center user's insurance type and place of residence: It showed higher use of public health center for free service beneficiaries residing in Seoul than residents in nearby or local area. The medical insurance types for hospital users were more various than those for public health center users. 3) The use of hospital for patients of hypertension, diabetes mellitus and hyperlipidemia was tended to concentrate in mostly autumn and winter since August 2000, while the cost of using public health center for those patients has been steadily reduced since July 2000. 4) As a result of cluster analysis, there were classified into three homogeneous groups according to the total cost of using public health service, age, and the frequency of use. 5) The association analysis on patients with chronic disease in public health center produced a detailed information on accompanying diseases related to the incidence rate of disease of high frequency due to aging, information on drug abuse and immune disease. Conclusion: The health care policy for local community should be evaluated continuously. And the policy to build an integrated data warehousing by public health indicator system and to enhance the faithfulness of data is required.
Journal of the Korean Institute of Landscape Architecture
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v.31
no.4
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pp.1-12
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2003
The urban park provides a safe rest and leisure area, and offers the beauty of nature to counter the drearyness of urban space. It can provide benefits such as the reduction of environmental pollution, the regulation of the local climate, and it can also provide a safe area during times of disaster. However, there was no interest in urban park development and control in Korea during the economic boom of the mid 1960s. Furthermore, during the industrialization process, the population grew significantly in the cities and the cities' scales were noticeably extended; as a result of this, the living environment and the natural environment in the cities worsened. With rapid urbanization and industrialization, urban green area diminished, and it became necessary to organize the urban park system to improve quality of life. 45% of south korea's population lives in 6 cities, which is only 4% of Korea's land size. The Urban park system has to be considered in the urban planning process. Paris' urban green system can be a role-model for Korea's urban green development plan to function organically. Urban public park concepts have been used in Paris's urban planning since 1850. There were hardly any parks, gardens and squares for the public before the middle of the 19th century. For improving life-styles for the poor, Napoleon III strongly supported the development of green space systems in Paris by G.E. Haussmann. Napoleon III and Haussmann established and applied the urban green regulation within Paris urban planning. The purpose of this study is to investigate the green regulations Haussmann's Paris urban plan and urban green space system: and as a result of this, it can be an indicator for urban green space development in Korea.
Journal of the Korean association of regional geographers
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v.3
no.2
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pp.89-103
/
1997
This Study is an analysis of the tourism geography for Past thirty years and an indicator for the future. I searched for the specificity by classifying of subjects, periods, and Researcher's achievements and tendencies. The Results are followings: (1) Sightseeing places are superior to visitors in research activities. Research activities are outstanding in developing sightseeing site and Its effect as well as geographical research about city and hot spring. The research activity to tourist was occupied a great number tourist behaviour to tourism place but the research was insufficied somewhat inhabitants in tourism place. (2) According to the period and results analysis. The period of domestic study is divided in to 3 steps. 1970s are said to be the pre-step for developing, 1980s are said to be growth step, but 1990s are considered as the age of maturity in the multiful research realm and broad theme. Finally, I think it is difficult to analyse total outcome to the tourism geography by limited data. This study will be evidencied on the objective standard by multiful data in nearly future because this indwelled in the subjectivity on the subject choice and process of the object classification.
In this study, we analyzed the value of Chl-a by histogram to classify the points where algal management is required. The degree of algal bloom by point was analyzed using the ogive curve, and the algal control points were classified into three stages according to the shape of the frequency distribution table. Of the four major rivers, low concentration of Chl-a appeared most frequently in the Han River, while the high concentration of Chl-a was frequently found at the points of the Geum and the Yeongsan Rivers. In the case of the Han River, no apprehensive areas were found thatrequire intensive management, while most points on the Geum and the Yeongsan Rivers required algal management. Finally, the Nakdong River basin was identified as points requiring algal management from the mid to downstream. The results of this study have confirmation of the possibility that the frequency distribution could be used as a supplementary indicator to express the algal bloom.
Patent information analysis has been carried out for technological capability analysis of competitors relating to next generation mobile communication. Various analysis methods, such as applicant analysis, technology classification analysis, indicator analysis and the like have been utilized as a method of analyzing patent information. As a first step for the technological capability analysis of competitors, applicants having high patent activity(PA) were selected, and as a second step therefor, technology classifications showing high technological independence (TI) were selected. Furthermore, portfolios for technology classifications showing high technological independence in the patents of main applicants having high patent activity by matching results the first and second steps together were prepared. Through such a process, portfolios for important technologies which have been concentrically researched by competitors could be analyzed. Accordingly, the present analysis results will help to carry out strategic R&D management, such as the establishment of company R&D plans and patent strategies.
Leading soybean cultivars such as Kwanggyo, Yugu No.3, Dongbugtae, Gangrim, and Eundaedu were heavily diseased by a virus in Korea. The disease was most severe in the northern provinces where soybean mosaic virus also occurrs, but the disease has also been observed in other provinces where soybean diseases are less prevalent. The disease symptoms were similar to bud blight caused by tobacco ringspot virus; but this was not confirmed in inoculation tests on indicator plants and serological experiments. There were some differences in varietal susceptibility to the disease, with symptom variation depending on the soybean cultivar and source of inoculm. Disease symptoms on infected soybean plants were mottling and necrosis. The present results, therefore, indicate some strains of SMV or a mixture of legume viruses may or may not be responsible for the disease.
Maternal and child health(MCH) status is considered as an important indicator of the level of health and civilization of a community and a country. MCH services for the rural population in the remote ar deserves priority by the government, since more than half(52.9%) of the delivery was occured at home and almost half (45.5%) of the delivery was assited by family members or neighbors. The purpose of the study was to analyse the health fare behavior related to pregnancy and delivery, which can be contributed maternal health care policy mating for the rural people. Specifically, it was intended to analyze the variables which affect the health care behavior in selecting birth places and birth attendants. This study utilized the data which had been already collected for an experimental study on primary health program model in Korean rural communities, funded by the USAID. 184 sample households with women who had delivered a baby during March 1982 to February 1983 were selected. Discriminant Analysis was employed for statistical analysis by utilizing SPSS computer package program. Birth places and birth attendants were considered as dependent variables. Among 12 independent variables in 5 groups considered, 7 independent variables were found statistically significant to affect the selection of birth place. Significant variables by the order of importance are mother's age, order of baby, number of prenatal care, accessibility of emergency medical care, coverage of medical insurance, mother's membership in community organization and husband's educational level. The degree of correct classification of the grouped cases by employing a discriminant . analysis was significantly improved to 78.2% in comparison to Cmax(56%) and Cpro(51%). Policy implications for each significant variable were discussed to improve the maternal and child health. in Korean ruralarea.
Vegetational data from 25 quadrats of Quercus mongolica communities at Hangyeryong and Paekdamsa area in Soraksan National Park were analysed by applying two multivariate methods: two-way indicator species analysis(TWINSPAN) for classification and canonical correspondence analysis(CCA) for ordination. The forest vegetation of Quercus mongolica community was classified into Quercus mongolica-Tilia amurensis, Quercus mongolica-Abies holophylla, Quercus mongolica-Styrax obassis, and Quercus mongolica-Quercus serrata groups according to the TWINSPAN. The relationships between the distribution of dominant groups according ot the TWINSPAN. The relationships between the distribution of dominant groups for forest vegetation and soil condition in Quercus mongolica communities were investigated by analysing elevation and soil nutrition gradients. Quercus mongolica-Tilia amurensis group was distributed in the high elevation and poor nutrition area of total nitrogen and C.E.C., Quercus monholica-Abies holophylla group was distributed in the high elevation and good nutrition area of total nitrogen and C.E.C., Quercus mongolica-Styrax obassia group was distributed in the medium elevation and poor nutrition area of total nitrogen and C.E.C., while Quercus mongolica-Quercus serrata group was distributed in the low elevation and poor nutrition area of total nitrogen and C.E.C.. The dominant factors influencing community distribution were elevation, total nitrogen and C.E.C..
Journal of Agricultural Extension & Community Development
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v.18
no.4
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pp.825-860
/
2011
For the first time basic settlement area development plan was established in 2010, in order to promote cooperative coexisting development among regions, as time that regional competitiveness determines national competitiveness started. Basic settlement area development plan is composed of 7 sectors and 24 general subsidy projects. It was judged that experience and tourism business as the center is required to be analyzed, which may have effect on activation of farm village, fishing village and mountain village, and inflow of city people, in agriculture, forestry and fishery sector in order that added value of agriculture and fishery is increased, and tangible and intangible resources are applied, and pure agriculture, forestry and fishery is developed. And currently farm village, mountain village and fishing village of our country faces desperate crisis situation that they cannot help groping for substitutive to create new revenue model, and agriculture and fishery of primary industry has limit of increasing income of farmer and fisherman. Agriculture, forestry and fishery experience and tourism business was classified by types, and then standard of 12 categories and 48 sections was prepared, for searching method to supplement and develop it. Trend of experience and tourism business was understood, and problem was found, and then it may be used as indicator material to carry out creative and differentiated business plan establishment and business operation, and may be opportunity to reject overlapped business among regions, and to promote balanced regional development.
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