• Title/Summary/Keyword: CHO

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Pharmacognostical Studies on the ‘Cho Pi Na Mu’ (초피나무의 생약학적 연구)

  • Park, Jong-Hee;Park, Seong-Su;Kim, Jeong-Myo
    • Korean Journal of Pharmacognosy
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    • v.33 no.2 s.129
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    • pp.75-80
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    • 2002
  • The Korean folk medicine 'Cho Pi Na Mu' has been used orally to tuberculosis, neuralgia, acute and chronic gastritis and arthritis. In order to clarify the botanical origin this crude drug, comparative anatomical studies were made on the branches of Zanthoxylum species growing wild in Korea, i.e. Z. coreanum, Z. piperitum, Z. piperitum var. pubescens, Z. planispinum, Z. schinifolium, Z. schinifolium var. inermis, Z. schinifolium var. microphyllum. As a result, it was clarified that 'Cho Pi Na Mu' was the branch of Z. piperitum.

Fabrication and New Model of Saturated I-V Characteristics of Hydrogenerated Amorphous Silicon Thin Film Transistor (비정질 실리콘 박막 트랜지터 포화전압 대 전류특성의 새로운 모델)

  • Lee, Woo-Sun;Kang, Yong-Chul;Yang, Tae-Hwan;Chung, Hae-In
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1992.11a
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    • pp.3-6
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    • 1992
  • A new analytical expression for the saturated I-V characteristics of hydrogenerated amorphous silicon thin film transistors(a-si:H TFT) is presented and experimentally verified. The results show that the experimental transfer and output characteristics at several temperatures are easily modeled. The model is based on three functions obtained from the experimental data of $I_D$ versus $V_G$. Theoretical results confirm the simple form of the model in terms of the device geometry. It was determined that the saturated drain current increased at a fixed gate voltage and the device saturated at increasingly larger drain voltages while the threshold voltages decreased.

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Development of the Phase Difference Controller of Ultrasonic Motor using PLSI method (PLSI를 이용한 초음파 모터 위상차 제어기 개발)

  • Kim, Dong-Ok;Lee, Kam-Youn;Kim, Won-Bae;Choi, Han-Soo;Kim, Young-Dong
    • Proceedings of the KIEE Conference
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    • 1995.11a
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    • pp.182-185
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    • 1995
  • The travelling ultrasonic motor(USM) has good some characteristics over conventional servo motors such as compact size, light weight, silent moton, high torque and high speed response. The USM is driven by 2-phase AC electricity. By adjusting the phase difference of the motor power we control rotation, speed and torque of USM. In this paper, we propose design method using PLSI(programmable Large Scale Integration) of USM controller to adjust the phase difference of the motor power. As compared the previous, the new controller has some advantage that high speed, predictable performance, low power and so on.

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Genotoxicological safety of the Gamma-Irradiated Medicinal Herbs in the Micronucleus Test Using CHO Cells In Vitro (CHO 세포에서의 소핵시험을 이용한 감마선조사 생약재의 안전성에 관한 유전독성학적 평가)

  • 조성기
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.26 no.5
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    • pp.952-957
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    • 1997
  • The three medicinal herbs-Curcuman longa Linne, Paeonia japonica Miyabe, Scutellaria baikalensis George-irradiated with gamma rays were tested for their possible genotoxicity. The methanol-soluble and water-soluble fractions of the 10kGy gamma-irradiated herbs were examined in cultured Chinese hamster ovary(CHO) cells for their ability to induce micronuclei. No mutagenicity of each test material was detected in the assay with or without metabolic activation. The safety of the herbs irradiated with gamma rays at practical doses needs further investigations using in vivo genotoxicity and chronic and reproductive toxicity tests.

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Formation Mechanism of Aroma Compound during Tea Manufacturing Process (차 향기의 생성 메커니즘)

  • Cho, MiJa;Cho, Gijeong;Choi, HyunSook;Choi, Dubok;Cho, KiAn;Cho, Hoon
    • KSBB Journal
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    • v.31 no.2
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    • pp.91-99
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    • 2016
  • Tea is an aqueous infusion of dried leaves of the plant Camellia sinensis L. and is the second most widely consumed beverage around the world after water. Aroma compounds of tea differ largely depending on the manufacturing process, even from the same categories of different origins. The flavor of tea can be divided into two categories: taste (non-volatile compounds) and aroma (volatile compounds). In the present study, we review the formation mechanism of main aromas generated from carotenoids, lipids, glycosides as precursors, and Maillard reaction during the tea manufacturing process, with biological and chemical mechanisms.

A Study on the 'Ohdae Eubuga' of Suheon Lee Jung Kyeung (새로 발굴된 이중경의 오대어부가)

  • Chang In Jin
    • Journal of the Korean Society for Library and Information Science
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    • v.10
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    • pp.149-188
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    • 1983
  • This study is about a literary man, Suheon Lee Jung Kyeung(AD. 1599-1678) and his poem 'Ohdae Eubuga' written in the language of the common people(RiEu) of Cho Seon dynasty. The outline of this study are as follows: 1) The work has been written at Ohdae, Cheongdo Gum, Kyeung-sang Do, in AD. 1656 that is the 7th year of King Hyo Jong of Cho Seon dynasty. 2) The work was written in the Korean and Chinese characters, in the form of the ancient Korean ode (Sijo). The twenty odes are composed of 'Eubuga' with 14 poems and 'Eububyeulgok' with 6 poems. The pleasureof his public life was well represented in these poems. 3) The work is included in his original manuscript 'Japhwewonjib' written in AD. 1664, the 5th year of King Hyeun Jong of Cho seon dynasty. 4) It seemed that the work has been mostly influenced by 'Mooyee Gugokga' of Joo Hee(AD. 1130-1200) of South Song dynasty, 'Eubusa' of Nongam Lee Hyeun Bo(AD. 1467-1555) and 'Dosan Sibyeegok' of Toegei Lee Hwang(A.D. 1501-1570) of Cho Seon dynasty.

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Rotation Speed and Torque Characteristics of Ultrasonic Motor by Phase difference (위상차에 의한 초음파 모터의 속도와 토오크 특성)

  • Kim, Dong-Ok;Ko, Nack-Yon;Choi, Han-Su;Cha, In-Su;Woo, Su-Yong;Kim, Young-Dong
    • Proceedings of the KIEE Conference
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    • 1994.07a
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    • pp.328-330
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    • 1994
  • The Ultrasonic motor(USM) has many good characteristics such as high torque at low speed range, large holding torque based upon frictional force, high speed response, flexible free ferns, compactness in size, low magnetic noise and silentness in motion. Because of having low speed rotation, USM is good as an actuator of a small size direct drive (DD) manipulator. The acturators for the DD manipulators must have good controllability on the speed and torque from zero to maximum value continuously. New method was developed for speed and torque control by the phase difference control of the two-phase driving signals of the motor. Then rule adjustable compliant and dumped motion was realized on the output shaft of the motor by PD control of the output shaft angle.

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Use of Flp-Mediated Cassette Exchange in the Development of a CHO Cell Line Stably Producing Erythropoietin

  • Kim, Min-Soo;Lee, Gyun-Min
    • Journal of Microbiology and Biotechnology
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    • v.18 no.7
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    • pp.1342-1351
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    • 2008
  • The feasibility of the use of Flp-mediated cassette exchange in the development of a CHO cell line, which produces erythropoietin (EPO) stably and largely, was investigated. A stable, high enhanced green fluorescence protein (EGFP)-producing clone was screened by extensive flow cytometric analysis. An EPO expression unit was targeted into the premarked locus of the stable parental clone by Flp-mediated cassette exchange and a correctly targeted clone (FC28T7) was obtained. The EPO production of FC28T7 was proven to be stable in long-term culture. Furthermore, the Flp-mediated cassette exchange did not alter the stable parental clone's characteristics concerning transgene expression level and stability. Taken together, the data obtained here indicated that the establishment of CHO cell lines stably producing a desired protein is achievable using Flp-mediated cassette exchange.

A Study on Ultrasonic Motor Speed Control Characteristic with Neural Networks (신경회로망을 이용한 초음파모터의 속도 특성에 관한 연구)

  • Cha, In-Su;Cho, Je-Hwang;Kim, Pyeng-Ho;Song, Chan-Il;Lee, Sang-Il
    • Proceedings of the KIEE Conference
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    • 1995.07a
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    • pp.39-41
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    • 1995
  • The inherent performance of Ultrasonic Motor(USM) which is on of highlighted a directly-driven positioning servo motor/actuator. In this paper, the speed of control USM based on neural network control. The neural network control can roughly be classified as the direct control and indirect control schemes. An indirect control scheme is adopted for Ultrasonic Motor speed control. A back propagation algorithm is used to train neural network controller. The Simulation results show that this neural network control system can provide good dynamical responses.

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PROTECTIVE EFFECT OF SELENIUM ON GLUTATHIONE METABOLISM BY MERCURY TOXICITY IN THE CHO CELLS

  • Byun, Boo-Hyung;Cho, Su-Jung;Chung, An-Sik
    • Toxicological Research
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    • v.7 no.2
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    • pp.141-149
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    • 1991
  • The treatment with 5ng/ml of mercuric chloride caused time-dependent decreases, and in the activities of GSH S-transferase and GSH-peroxidase, and in the concentration of GSH in CHO cells. Three hours after treatment of $Hg^{2+}$, the activity of GSH S-transferase was decreased to almost half value of control group and the activity of GSH-peroxidase was reduced significantly at 6 hr after treatment. The concentration of GSH was decreased 2 hr after treatment of $Hg^{2+}$ and was decreased to nearly half value of control group 3 hr after treatment.

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