• 한국산학기술학회논문지
• /
• 제18권4호
• /
• pp.660-668
• /
• 2017

본 연구는 작업환경측정기관 분석실에서 많이 다루어지고 있는 유해화학물질에 대해 CHARM(Chemical Hazard Risk Management)을 이용한 위험성평가를 실시하고 위험성을 추정하였다. 이를 위하여 서울 및 경기지역의 위험성평가를 실시한 작업환경측정기관 6곳을 선정하였으며, 그 결과 화학물질 노출 위험성 물질은 29개 물질이 선택 되었다. 성상별로는 액체 16개, 고체 10개 물질이었고, 특별관리물질인(CMR) '발암성(Carcinogenic)' 1A - 11개, 1B - 1개, 2 - 8개, '생식세포변이 원성(Mutagenic)' 1A - 4개, 1B - 3개, 2 - 8개, '생식독성(Repro-toxic)' 1A는 해당물질이 없고, 1B - 1, 2 - 6개 물질이 포함되어 있었다. 위험성 추정 결과 '낮음'에 해당하는 물질은 30.4%, '보통' 66.1%, '높음' 3.6%로 평가 되었다. 또한 6개 기관의 각 물질별 위험성 추정 결과 2개 기관이 위험성 추정 결정 중 '높음'에 해당하는 물질을 포함하고 있었다. 본 연구를 통하여 화학물질 평가도구인 CHARM(Chemical Hazard Risk Management)을 이용한 위험성 평가를 시도하였다는데 그 의의가 있으며, 작업환경측정기관 분석실의 위험성과 관리 화학물질을 우선적으로 도출하여 안전성 평가 및 비상조치 계획 수립과 안전관리 매뉴얼 구축과 작업환경측정기관 분석실에 대한 사고 및 위험성 관리의 제도적 법적 관리의 기초 자료로 활용되기를 기대한다.

• 한국토양비료학회지
• /
• 제47권2호
• /
• pp.133-139
• /
• 2014

Veterinary antibiotics (VAs) in animal compost and organic fertilizer can have adverse effect on ecosystem and eventually human health. The main purpose of this research was to evaluate feasibility of Charm II system for monitoring residuals of VAs in animal compost and organic fertilizer. Four different VAs (Tetracyclines: TCs, Sulfonamides: SAs, Macrolides: MLs, and ${\beta}$-lactams: ${\beta}$-LTs) were analyzed and total of 100 samples were monitored. Results reveled that SAs in animal compost showed the highest detection frequency (64%) with exceeded concentration of criteria. However, very low detection frequency (0-12%) for ${\beta}$-LTs was observed in animal compost and organic fertilizer. Depending on physicochemical properties of each VAs, detection frequency of VAs was determined. In conclusion, charm II system can be utilized to screen if residual of VAs is in animal compost and organic fertilizer. Also, more research is necessary to establish standard method for analysis of VAs in complex matrix and to minimize adverse effect of VAs from source to environment.

• 한국자원식물학회:학술대회논문집
• /
• 한국자원식물학회 2018년도 추계학술대회
• /
• pp.121-121
• /
• 2018

We previously showed that the root extract of Paeonia lactiflora Red Charm might have anti-oxidant activities, however it was not clear which components might be involved in this activity. Our boinformatics analysis indicated the root extracts of Paeonia lactiflora Red Charm has a couple of potential anti-oxidant materials. One of them is paeoniflorin. We hypothesized that one of components present in Paeonia lactiflora Red Charm, paeoniflorin and its derivatives might be related to anti-oxidant activity. In this study, we compared paeoniflorin and its derivatives with the root extract of Paeonia lactiflora Red Charm using DPPH assays to measure its antioxidant activities. Paeoniflorin showed the highest radical scavenging activity(%) in $1000{\mu}g/m{\ell}$. its derivative showed the high levels radical scavenging activity(%) in $600{\mu}g/m{\ell}$, $800{\mu}g/m{\ell}$, $1000{\mu}g/m{\ell}$ similar to ascorbic acid. Taken together, these results suggest that Paeoniflorin and its derivatives may play a role in anti-oxidant acitivity in the root extracts of Paeonia lactiflora. Much of future studies may be needed to develop a potential new anti-oxidant candidates with anti-aging and anti-cancer effects.

• 한국동물위생학회지
• /
• 제21권1호
• /
• pp.13-20
• /
• 1998

This survey was carried out to detect the residual antibiotics and sulfonamides in emergency slaughtered cattle(n=265) from slaughter houses in Kyeonggi province by EEC 4-plates method, Charm II and HPLC. The results were summarized as follows ; 1. Antimicrobial substances were detected from 24 samples(9.1%) by EEC 4-plates method and the detection ratio were highest in summer(13.8%). 2. Twenty-two of the 24 positive samples were classified as sulfonamide(34.4%), TCs(31.3%), $\beta$-lactam(23.5%) and aminoglycoside(9.3%) by Charm II test. 13(59.1%) of the 22 samples contained single agent and 9 samples(40.9%) contained 2 or more agents. 3. Oxytetracycline(27.3%), penicillin G (27.3%) and sulfathiazole(18.2%) were detected in 20 from 22 samples by the HPLC and Charm II test. 4. The residual concentration of oxytetracycline, penicillin G and sulfonamide were 0.29~9.30 ppm, 0.05~9.58 ppm and 0.04~7.59 ppm, respectively and 19 samples(7.2%) were exceeded tolerance levels.

• 한국동물위생학회지
• /
• 제29권3호
• /
• pp.331-338
• /
• 2006

This survey was carried out to detect the residual antibiotics in beef (n = 1,071), pork (n=7,837) and chicken (n=1,536) from slaughter houses in Gyeongbuk province by EEC-4 plate method, Charm II and HPLC during 2005. Residues of antibiotic were detected from 9 beef (0.8%) and 119pork (1.52%) by EEC-4 plate method, and total positive rates were 1.23% (128). 126 samples of the 128 positive samples by the EEC-4 plate method were detected by charm II test. 128 samples were classified as tetracyclines 110 (95.5%), ${\beta}$-lactam 2 (1.6%), sulfonamide 22 (17.2%), quinolone 1 (0.8%). The highest residual concentration of oxytetracycline, tetracycline, chlor-tetracycline, penicillin, sulfamethazine, sulfadimethoxine, sulfaquinoxaline, sulfamerazine, sulfamonomethoxine and enrofloxacin were 7.57, 0.27, 0.40, 0.24, 14.24, 4.33, 8.59, 0.12, 0.09 and 1.98 ppm, respectively and 49 samples were exceeded legal admitted levels.

• 한국동물위생학회지
• /
• 제27권3호
• /
• pp.265-272
• /
• 2004

It was carried out to compare the residual materials by EEC 4-plate, Charm II and HPLC method in the muscles of cattle and pigs from slaughter-houses in Seoul from 2000 to 2003. Residual materials were detected from $1.10\%$(73/6,623) samples by EEC 4-plate method, and $10.93\%$(55/503) samples by Charm II method. The highest residual concentration(ppm) of oxytetracycline, tetracycline, chloramphenicol, chlortetracycline, sulfamethazine, sulfamerazine, sulfadimethoxine, penicillin and sulfamonomethoxine were 25.5, 3.46, 3.26, 1.5, 0.3, 0.2, 0.2, 0.14, and 0.07, respectively. Eighty nine samples were classified as 58($65.17\%$) only tetracyclines, 20($22.47\%$) only sulfonamides, 3($3.37\%$) only ${\beta}$-lactams, 2($2.25\%$) only chloramphenicol, 4($4.49\%$) tetracyclines and sulfonamides simultaneously, 1($1.12\%$) chloramphenicol and sulfonamides simultaneously, and 1($1.12\%$) chloramphenicol, sulfonamides and tetracyclines simultaneously.

• 대한본초학회지
• /
• 제23권1호
• /
• pp.63-74
• /
• 2008

Objectives : This study has been carried out to understand the effect of Uncooked Korean Food(F-DM) on blood glucose and antioxidant enzyme activities in streptozotocin-induced Diabetic Rats. Methods : SD rats were separated into four groups(each with 20 rats). Except normal two group, the other two groups were injected into intra-peritoneal with streptozotocin 60 mg/kg. Experimental group was eated Feed with 25% F-DM for 4 weeks. The change of plasma glucose level, body weight were observed. After 4 weeks, liver and kidney weight, antioxidant enzyme activities, survival rate were observed with histological changes on liver, kidney and pancreas. Results : In experimental group, body weight and survival rate increased, plasma glucose level were decreased significantly. Liver and kidney weight, XOD activity were decreased in experimental group compared to control group. GSH-px and CAT activities, insulin- immunoreactive granules in p-cells were increased significantly in experimental group compared to control group. Conclusions : This study shows that the F-DM might be effective for treatment of diabetes and its complications, as well as reduction of the oxidative stress.

• Ocean Systems Engineering
• /
• 제6권1호
• /
• pp.1-21
• /
• 2016

The global performance of the 5 MW OC4 semisubmersible floating wind turbine in random waves with or without steady/dynamic winds is numerically simulated by using the turbine-floater-mooring fully coupled dynamic analysis program FAST-CHARM3D in time domain. The numerical simulations are based on the complete second-order diffraction/radiation potential formulations along with nonlinear viscous-drag force estimations at the body's instantaneous position. The sensitivity of hull motions and mooring dynamics with varying wave-kinematics extrapolation methods above MWL(mean-water level) and column drag coefficients is investigated. The effects of steady and dynamic winds are also illustrated. When dynamic wind is added to the irregular waves, it additionally introduces low-frequency wind loading and aerodynamic damping. The numerically simulated results for the 5 MW OC4 semisubmersible floating wind turbine by FAST-CHARM3D are also extensively compared with the DeepCWind model-test results by Technip/NREL/UMaine. Those numerical-simulation results have good correlation with experimental results for all the cases considered.

• 한국동물위생학회지
• /
• 제20권2호
• /
• pp.225-233
• /
• 1997

In an effort to Improve the quality of meat and to monitor farms, residual tetracyclines in local beef and pork produced in the province of North Chung-cheong were determined by a EEC 4-plate, Charm II and HPLC, respectively. The results were summarized as follows ; 1. Of the 547 samples, 4 beef and 13 pork samples were judged to be positive by EEC 4 - plate method. 2. Detection rates of tetracyclines by type 1(++--) and type 2(+++ or ++$\pm$-) micro-bial growth Inhibition In EEC 4-plate method were 100% and 71%, respectively. 3. Of 17 positive samples, 6 were positive for tetracyclines, 4 were positive for tetracyclines and sulfonamides, 1 was positive for sulfonamides, and 2 were positive for others by Charm II test. 4. The best eluents were 0.01M methanolic oxalic acid, and the ideal temperature for stable concentration was $40^{\circ}C$ as optimal HPLC analytical conditions for the detection of tetracy-clines. 5. Of the 10 positive samples for tetracyclines by Charm II test, tetracyclines were confirmed in 2 beef and 6 pork samples, using HPLC, at levels ranging from 3.64~4.22 ppm and 0.2~1.20 ppm, respectively.

• 한국육종학회지
• /
• 제41권4호
• /
• pp.616-619
• /
• 2009

절화장미 "레드참" 품종은 전라남도농업기술원에서 육성한 적색 스탠다드 품종으로 수세가 강하고 동계생산성이 높은 적색 "First Red"를 모본으로, 적색이며 화형이 예쁜 "Cardinal" 를 부본으로 하여 2003년에 인공교배하였다. 화형과 화색이 예쁘고 수량성이 우수하며 가시가 적은 1계통을 최종 선발하였다. 2007년부터 2008년까지 3회에 거쳐 특성 및 생산력검정을 실시하여 스탠다드 대형계 품종으로 화색이 적색이며 가시가 적고 흰가루병에 강한 특성을 가지고 있으며 꽃크기가 10.3 cm, 절화장이 70.7 cm, 절화수명이 9.8일로 수명이 길며 절화수량은 3회 검정결과 115.2본/$m^2$/년으로 대비품종 "레드벨벳"(105.8본/$m^2$/년)에 비해 8.9% 증대되었다.