• Title/Summary/Keyword: CD81

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이성체쌍의 열중성자포획단면적비 측정

  • Park, Hy-Eil;Kim, Heon-Jun;Lee, Chul
    • Nuclear Engineering and Technology
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    • v.4 no.4
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    • pp.340-344
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    • 1972
  • Isomeric ratios were measured for the capture of thermal neutron by $^{79}$ Br, $^{80}$ Se, $^{103}$ Rh, $^{115}$ In and $^{133}$ Cs as well as those of epi-cadmium neutron by $^{79}$ Br, $^{80}$ Se and $^{l33}$Cs. The measurements were performed by analysing decay curves obtained by ${\gamma}$-ray spectrometry after irradiation. The counting efficiency curve was determined by using the calibrated standard sources with overall uncertainties of about 1%. Isomeric ratios, given in $\sigma$ high spin/($\sigma$ high spin + $\sigma$ low spin), of $^{80, 80m}$Br, $^{81,81m}$Se, $^{014, 104m}$Rh, $^{116,116m}$In and $^{134, 134m}$Cs produced by thermal neutron activation were found to be 0.21$\pm$0.01, 0.14$\pm$0.02, 0.12$\pm$0.02, 0.69$\pm$0.07 and 0.058$\pm$0.004, respectively, Those values of $^{80, 80m}$Br, $^{81,81m}$Se, and $^{134, 134m}$Cs Produced by epi-cadmium neutron were found to be 0.19$\pm$0.02, 0.29$\pm$0.02 and 0.074$\pm$0.011, respectively. The experimental values obtained were compared with the theoretical values deduced from the statistical model. There were the general agreements between the theory and the experiment.t.

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A Study on Trace-metals in Korean Yeongdeok Crab and Russian Snow Crab (영덕대게와 러시아산대게의 체내 미량금속 함량 연구)

  • Kim, Cho-Ryeon;Yoon, Yi-Yong
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.14 no.3
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    • pp.147-153
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    • 2011
  • This study is to measure the differences of the trace-metals resulted from the different ecologies, such as nickel(Ni), copper(Cu), zinc(Zn), cadmium(Cd), plumbum(Pb), arsenic(As) and chrome(Cr) remaining in the parts of Korean Yeongdeok Crab (KYC) and Russian Snow Crab (RSC) based on ICP-MS. The recovery rate of each metal certified the reference materials (CRM) was in the average of 81~99%, which corresponded with the level required in Codex. The level of metals in the parts of KYC was in the order of Ni > As > Zn > Cu > Cr > Cd in the both male and female shell; the order of Zn > As > Cu > Cr > Ni > Cd in the leg flesh; the order of Zn > As > Cu > Cr > Cd > Ni in the body flesh; the order of Cu > Zn > As > Cd > Cr > Ni in the gill; the order of Cu > As > Zn > Cd > Ni > Cr in the male hepatopancreas; the order of Cu > Zn > As > Cd > Cr > Ni in the female hepatopancreas, thereby showing some differences. It was revealed that the levels of most metals (nickel, copper, zinc, arsenic and chrome) were similar between KYC and RSC except cadmium which was somewhat lower than that of KYC. However, the cadmium in RSC was discovered in high level in most of the parts, two times higher in the hepatopancreas, and four times in the gill. It was also revealed that the trace metal contents were changing according to the size of KYC; the metals with the highest level of Ni in shell, Zn in leg and body flesh, Cu in gill tended to decrease as growing, whereas the cadmium contents tended to increase overall and accumulated the most in hepatopancreas. The results showed there was a possibility that the phenomenon of bioaccumulation within hepatopancreas would increase as growing.

Evaluation of the Feasibility of Phytoremediation of Soils Contaminated with Cd, Pb and Zn using Sunflower, Corn and Castor plants

  • Chae, Mi Jin;Jung, Goo-Bok;Kang, Seong Soo;Kong, Myung Suk;Kim, Yoo Hak;Lee, Deog Bae
    • Korean Journal of Soil Science and Fertilizer
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    • v.47 no.6
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    • pp.491-495
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    • 2014
  • Phytoremediation is a technology using plants and associated soil microbes to reduce the concentrations or toxic effects of contaminants in the environments. It is regarded as a cost-effective, efficient, eco-friendly, and solar-driven technology with good public acceptance. This study was conducted to find the plants accumulating heavy metals in soils contaminated with Cd and Pb. Experimental plots (plot size: $0.81m^2$) was artificially contaminated using a contaminated soil collected from a field in vicinity of Wondong mine (WD). Sunflower, corn and castor were tested for their potential to remove heavy metals from the contaminated soils. The results indicated that sunflower was most effective in accumulating heavy metals and thus remedying the soils among the three crops. Dry weight and heavy metal uptake of sunflower shoot differed with growth period. For example, the Cd content of shoots including leaf and stem were 0.31mg, 2.23 mg, and 0.96 mg per plot at 4, 8 and 12 weeks after planting in Cd4-WD treatment; in addition, the dry weight of the shoots in Cd8-WD treatment was reduced due to heavy metal toxicity. This experiment showed that sunflower absorbed Cd, Pb and Zn in their shoots up to 8 weeks of planting; thereafter heavy metals uptake was diminished. This implies that the efficiency of these plants in cleaning the contaminated soils may be high at the early stage of plant growth.

Association of Intracellular $T_H1-T_H2$ Balance in CD4+ T-cells and MIP-$1{\alpha}$ in CD8+ T-cells with Disease Severity in Adults with Dengue

  • Kadhiravan, Tamilarasu;Saxena, Ankit;Singh, Amar;Broor, Shobha;Sharma, Surendra K.;Mitra, Dipendra K.
    • IMMUNE NETWORK
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    • v.10 no.5
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    • pp.164-172
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    • 2010
  • Background: We tested the hypothesis that dengue haemorrhagic fever (DHF) is associated with a $T_H1$-skewed immune response as opposed to dengue fever (DF). Methods: We estimated intracellular (in T-cells) and serum levels of designate $T_H1/T_H2$ cytokines [interferon-${\gamma}$ (IFN-${\gamma}$), interleukin-4 (IL-4), and tumor necrosis factor-${\alpha}$] and macrophage inflammatory protein-$1{\alpha}$ (MIP-$1{\alpha}$) at admission, 48h, and day 5 in 20 adults with dengue (DF=10, DHF=10) and 10 dengue-naive healthy controls. Results: At admission, intracellular IFN-${\gamma}$/IL-4 ratio in CD4+ T-cells and proportion of MIP-$1{\alpha}$-positive CD8+ T-cells were significantly higher in patients with DHF [7.21 (5.36~10.81) vs. 3.04 (1.75~4.02); p=0.011 and 6.2% (3.2~8.2%) vs. 2.4% (2.0~3.6%); p=0.023]. The latter showed a significant positive correlation with IFN-${\gamma}$/IL-4 ratio in CD4+ T-cells (Spearman's rho=0.64; p=0.003), percentage-change in haematocrit (rho=0.47; p=0.048), and serum alanine amino-transferase level (rho=0.61; p=0.009). Conclusion: We conclude that DHF is associated with a $T_H1$-skewed immune response. Further, MIP-$1{\alpha}$ in CD8+ T-cells is an important immunologic correlate of disease severity in dengue.

An Increased Proportion of Apoptosis in CD4+ T Lymphocytes Isolated from the Peripheral Blood in Patients with Stable Chronic Obstructive Pulmonary Disease

  • Ju, Jinyung
    • Tuberculosis and Respiratory Diseases
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    • v.81 no.2
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    • pp.132-137
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    • 2018
  • Background: The pathophysiology of chronic obstructive pulmonary disease (COPD) includes inflammation, oxidative stress, an imbalance of proteases and antiproteases and apoptosis which has been focused on lately. Abnormal apoptotic events have been demonstrated in both epithelial and endothelial cells, as well as in inflammatory cells including neutrophils and lymphocytes in the lungs of COPD patients. An increased propensity of activated T lymphocytes to undergo apoptosis has been observed in the peripheral blood of COPD patients. Therefore, the apoptosis of T lymphocytes without activating them was investigated in this study. Methods: Twelve control subjects, 21 stable COPD patients and 15 exacerbated COPD patients were recruited in the study. The T lymphocytes were isolated from the peripheral blood using magnetically activated cell sorting. Apoptosis of the T lymphocytes was assessed with flow cytometry using Annexin V and 7-aminoactinomycin D. Apoptosis of T lymphocytes at 24 hours after the cell culture was measured so that the T lymphocyte apoptosis among the control and the COPD patients could be compared. Results: Stable COPD patients had increased rates of $CD4^+$ T lymphocyte apoptosis at 24 hours after the cell culture, more than the $CD4^+$ T lymphocyte apoptosis which appeared in the control group, while the COPD patients with acute exacerbation had an amplified response of $CD4^+$ T lymphocyte apoptosis as well as of $CD8^+$ T lymphocyte apoptosis at 24 hours after the cell culture. Conclusion: Stable COPD patients have more apoptosis of $CD4^+$ T lymphocytes, which can be associated with the pathophysiology of COPD in stable conditions.

Effect of Mungbean Sprouts Juice on Cadmium-Induced Hepatotoxicity in Rats (녹두나물 생즙이 카드뮴에 의한 흰쥐의 간손상에 미치는 영향)

  • 이명렬;최인화;김성오;김경수
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.27 no.5
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    • pp.980-986
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    • 1998
  • The effects of mungbean sprout juice on cadmium-induced hepatotoxicity in rats were investigated. Sprague-Dawley rats weighing about 90g were divided into 4 groups and raised for 6 weeks. ; control group(CON), mungbean sprouts juice-administered group(MSJ), cadmium-administered group(CAD) fed water containing 40 ppm cadmium chloride and mung bean sprouts juice and cadmium-administered group(MCD). The diet was supplied every day for the measurement of feed efficiency ratio(FER) and net weight gain was measured every 3 days. The activities of serum glutamic oxaloactic transaminase(GOT) and glutamic pyruvic transaminase(GPT), superoxide dimutase(SOD), catalase and glutathione peroxidase(GSH-Px) in the liver and the hepatic contents of glutathione were examined. The contents of Cd in liver and kidney of the rats were determined by using ICP(Inductively Coupled Plasma Emission Spectrophotometer). Growth rate and FER were decreased in CAD group, compared with CON group but the changes were not significant in MCD group. The activities of serum GOT and GPT, SOD, catalase and GSH-Px in the liver were increased by Cd administration, but the alterations were decreased by supplementation with mungbean sprouts juice. The level of glutathione decreased in CAD group(26.8$\pm$9.0mg/g liver), whereas it increased in MCD group(36.4$\pm$15.8mg gliver). The content of Cd in the liver and kidney in MCD group(9.57 ppm, 4.88 ppm) was decreased, compared with CAD group(12.81 ppm, 5.46 ppm). This result suggested that mungbean sprout juice has a lowering effect on the accumulation of Cd in the liver and kidney and it is believed that the juice has some protective effects to Cd-induced hepatotoxicity in rats, but the mechanism of these effects was obscure.

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Heavy Metals in Road Deposited Sediments and Control of Them in Urban Areas: A Review (문헌고찰에 의한 도시 지역 도로퇴적물의 중금속 특성 및 적정 관리방안)

  • Kim, Do Gun
    • Land and Housing Review
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    • v.13 no.3
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    • pp.125-140
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    • 2022
  • Road Deposited Sediment (RDS) is the solids formed from the wear of road, wear of vehicles, exhausts, and the input of the emissions from various sources out of the roads. RDS is seriously polluted by organic matter, nutrients, and metals. RDS plays an important role as the sink and the transport medium of the associated pollutants because RDS can be carried to the adjacent water system via stormwater runoff. In this regard, the heavy metals in RDS were investigated based on the publications. The contents of the metals in RDS were highly variable. The concentration of Cr, Ni, Cu, Fe, Zn, As, Cd, and Pb in urban RDS in various regions was in a range of 3.16-3,410, 1.15-1,382, 20.2-9,069, 2,980-124,853, 81-2,550, 2.3-214, 0.19-21.3, and 15.21-1,125 mg/kg, respectively. The anthropogenic enrichment of the metals in RDS was confirmed by the high concentration of Cu, Zn, Cd, and Pb. The contents of the metals were higher in industrial and traffic areas than in residential areas, while they were generally increased with decreasing particle size. It is believed that this study's results would contribute to quantifying the metals' load via RDS and establishing control strategies.

Biosorption of Metal Ions by Seaweed Alginate, Polyguluronate, and Polymannuronate (알긴산, 폴리글루론산 및 폴리만뉴론산에 의한 금속이온의 흡착)

  • Jung, Dae-Young;Son, Chang-Woo;Kim, Sung-Koo;Kim, Yi-Joon;Chung, Chung-Han;Lee, Jin-Woo
    • Journal of Life Science
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    • v.19 no.5
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    • pp.553-560
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    • 2009
  • Based on $P_{1/2}$ values, relative affinities of alginate, polyguluronate, and polymannuronate for metal ions are, in order, as follows; 1) seaweed alginate: $Cu^{2+}$ > $Cd^{2+}$ > $Pb^{2+}$ > $Fe^{3+}$ >> $Zn^{2+}$ > $Sr^{2+}$ > $Ca^{2+}$ > $Co^{2+}$ >> $Cr^{6+}$ > $Mn^{2+}$ >> $Hg^{2+}$, $Mg^{2+}$, $Rb^+$, 2) polyguluronate: $Cd^{2+}$ > $Cu^{2+}$ > $Pb^{2+}$ > $Fe^{3+}$ >> $Ca^{2+}$ > $Sr^{2+}$, $Zn^{2+}$, $Co^{2+}$ >> $Mn^{2+}$ > $Cr^{6+}$ >> $Hg^{2+}$, $Mg^{2+}$, $Rb^+$, and 3) polymannuronate: $Cd^{2+}$, $Cu^{2+}$ > $Fe^{3+}$ > $Pb^{2+}$ > $Ca^{2+}$ > $Zn^{2+}$ > $Sr^{2+}$ > $Co^{2+}$ > $Cr^{6+}$ >> $Mn^{2+}$ >> $Hg^{2+}$, $Mg^{2+}$, $Rb^+$. Amounts of the metal ions, $Cd^{2+}$, $Cu^{2+}$, $Fe^{3+}$, $Pb^{2+}$, and $Zn^{2+}$, bound to 1 g of seaweed alginate, were measured as $363.5{\pm}45.0$, $226.3{\pm}9.2$, $1,299.4{\pm}$81.3, 500.7${\pm}$27.7, and 165.9${\pm}$11.4 mg, respectively. Amounts of the metal ions, $Cd^{2+}$, $Cu^{2+}$, $Fe^{3+}$, $Pb^{2+}$, and $Zn^{2+}$, bound to 1g of polyguluronate, were 354.5${\pm}$26.5, 177.6${\pm}$8.7, 1,288.6${\pm}$60.1, 424.0${\pm}$7.4, and 140.2${\pm}$28.5 mg, respectively, whereas those bound to 1 g of polymannuronate were 329.0${\pm}$10.3, 206.9${\pm}$1.9, 1,635.6${\pm}$11.1, 419.8${\pm}$12.6, and 251.0${\pm}$49.1 mg, respectively. Due to its higher solubility than alginate and higher affinity for metal ions than polyguluronate, polymannuronate can be used for bioremediation or biosorption of toxic and/or noble metal ions.

Effect of Kami-KangHwalSan on atopic dermatitis-like skin lesions induced in NC/Nga mice by mite antigen stimulation (가미강활산(加味羌活散)이 NC/Nga mice의 아토피 발진 억제에 미치는 실험적 연구)

  • Kim, Yun-Hee;Han, Jae-Kyung;Kim, Yun-Hee
    • Journal of Haehwa Medicine
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    • v.16 no.1
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    • pp.81-91
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    • 2007
  • Objective : We wished to examine closely effect that Kami-KangHwalSan medicines used to atopy dermatitis disease patient get in atopy eruption control experimentally. Materials and Methods : Atopic dermatitis (AD) usually develops in patients with an individual or family history of allergic diseases, and is characterized by chronic relapsing inflammation seen specially in childhood, association with IgE hyperproduction and precipitation by environmental factors. However, the exact etiology of AD has been unclear. To further explore the pathogenesis and treatment of AD, a suitable animal model is required. We found that skin lesions, which were chnically and histologically very simlar to human AD, mite antigen-induced dermatitis on the face, neck, ears and dorsal skin of inbred NC/Nga mice. Results and Conclusion : Kami-KangHwalSan medicines controlled CD3+/CD69+, CD4+/CD25+, B220+/IgE+, and B220+/CD23+ revelation that an experiment that motive allergy immune reponse because an in vitro experiment stimulates splenocytes of a NC/Nga mouse same t1me by PWM, and interleukin-4, eotaxin 2, CCR3, TARC mRNA outturn that bear in splenocytes decreased remarkably by Kami-KangHwalSan medicines. Th1 cell and Th2 cell observe to be shifted by secretion amount of IL-4 and IFN-$\gamma$ by Kami-KangHwalSan medicines could know that Kami-KangHwalSan medicines can use usefully in allergy autoimmnune diease.

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Removal of Hazardous Heavy Metals (Cd, Cr, and Pb) from Laver Pyropia sp. with Acid Treatment (산 처리에 의한 김(Pyropia sp.)의 유해 중금속(Cd, Cr, Pb) 제거 효과)

  • Mok, Jong Soo;Son, Kwang Tae;Lee, Tae Seek;Lee, Ka Jeong;Jung, Yeoun Joong;Kim, Ji Hoe
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.49 no.5
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    • pp.556-563
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    • 2016
  • We examined the removal of hazardous heavy metals (Cd, Cr, and Pb) from laver Pyropia sp. using citric, hydrochloric, and nitric acids. Under the same conditions, the quality of the laver samples was also evaluated using the variation in absorbance and major mineral levels. The heavy metals that accumulated in raw laver samples after 3 days in seawater included Pb (117.79 μg/g), Cr (33.53 μg/g), and Cd (10.54 μg/g) in descending order. The rate of heavy metal removal from laver was higher at lower pH for all acids used. However, its color changed unsatisfactorily at pH 2.0. After 10 min in seawater at pH 2.5, the heavy metals in laver were eliminated in the order Cd (68.7–81.6%), Pb (57.7–67.0%), and Cr (31.9–49.4%) using the three acids. The differences in heavy metal removal among acid types were not significant. The laver quality was not affected after 20 min at the pH range of 2.5–4.0. The maximum removal of heavy metals was from laver soaked for 10 min in seawater at pH 2.5 using the organic acid, citric acid.