• 한국섬유공학회:학술대회논문집
• /
• 한국섬유공학회 1998년도 봄 학술발표회 논문집
• /
• pp.325-328
• /
• 1998

$\beta$-cyclodextrin($\beta$-CD)은 cycloheptaamylose라고도 하며 $D^{＜+>}$-glucopyranose 단위체가 7개 연결된 구조를 가지고 있다(Fig. 1). $\beta$-CD는 고리모양으로 되어있는데 외부는 친수성, 내부는 소수성을 갖는다[1]. 고리내 부가 소수성인 이유는 내부에 소수성기인 C-H그룹과 glucosidic oxygen만이 존재하기 때문이다[1].(중략)

• Bulletin of the Korean Chemical Society
• /
• 제31권9호
• /
• pp.2537-2541
• /
• 2010

We chose a fluorescent pentapeptide sensor (-CPGHE) containing a dansyl fluorophore as a model peptide and investigated whether the selectivity and sensitivity of the peptides for heavy and transition metal ions could be tuned by changing amino acid sequence. In this process, we developed a selective peptide sensor, Cp1-d (-HHPGE, $K_d\;=\;670\;nM$) for detection of $Zn^{2+}$ in 100% aqueous solution and a selective and sensitive peptide sensor, Cp1-e (-CCHPGE, $K_d\;=\;24\;nM$) for detection of $Cd^{2+}$ in 100% aqueous solution. Overall results indicate that the selectivity and sensitivity of the metallopeptide sensors to specific heavy and transition metal ions can be tuned by changing amino acid sequence.

• 한국진공학회지
• /
• 제16권6호
• /
• pp.458-462
• /
• 2007

타원편광분석법은 반도체 물질의 광 특성과 전이점 연구에 유용하게 쓰이는 기술이다. 측정된 유전율 함수로부터 전이점을 구하기 위해서 전통적으로 이차 미분스펙트럼을 이용하여 분석하는데, 이 방법은 high frequency 의 잡음을 크게 증폭시키는 단점이 있다. 본 연구에서는 역 공간 푸리에 변환 (Fourier transform)을 이용하여 low-, medium-, high-index 의 푸리에 계수로부터 baseline, 정보, high frequency 잡음을 분리하는 방법을 소개하고자 한다. 이 방법을 이용하여 광전자소자에 폭넓게 사용되는 ZnCdSe 화합물 반도체의 $E_1,\;E_1+{\Delta}_1$ 전이점에 대한 연구를 하여 전통적인 이차 미분법과 비교해 보았다.

• Bulletin of the Korean Chemical Society
• /
• 제32권9호
• /
• pp.3255-3260
• /
• 2011

Two novel binuclear metal-organic coordination complexes $[Cd_2(L)_2(bpy)_2(H_2O)_2]{\cdot}6H_2O$ (1), $[Cd_2(L)_2(phen)_2-(H_2O)_2]{\cdot}2H_2O$ (2) (where L = 2-methylquinoline-3,4-dicarboxylate dianion, bpy = 2,2'-bipyridine, phen = 1,10-phenanthroline) have been synthesized under hydrothermal conditions and characterized by single crystal Xray diffraction, spectral method (IR), elemental analysis and thermal gravimetric analysis (TGA). Both 1 and 2 consist of two Cd(II) atoms bridged by two monoatomic bridging carboxylate groups from two L ligands, and the second carboxylate group of each L is monodentately coordinated to Cd(II), creating a sevenmembered chelating ring. The coordination at each metal nucleus is completed by a water molecule and a chelating bidentate molecule. The 3D structures of the complexes are stabilized by ${\pi}-{\pi}$ stacking interactions and hydrogen-bonds.

• Radiation Oncology Journal
• /
• 제14권1호
• /
• pp.53-59
• /
• 1996

목적 : 암환자에서 방사선치료에 의한 면역기능의 저하에 대해서는 많은 보고가 되어 있다. 저자들은 방사선치료부위중 비교적 활동성 골수를 많이 포함하고 있는 흥부 및 골반강조사 직후 어느정도 면역력의 저하가 오는지 알아보고자 하였다. 대상 및 방법 : 1995년 1월부터 1995년 4월까지 등록된 61 명의 환자중 48 명을 대상으로 분석 하였다. 이중 흉부(조사문, >$150cm^2$)에 방사선치료를 시행한 환자는 29명이었고 전골반강부에 방사선치료를 시행한 환자는 19명 이었다. 연령분포는 36세에서 73세 였으며 평균 및 중간값 모두 57세 였으며 남녀비는 1.3(27/21)이었다. 환자의 면역기능의 지표는 말초혈액검사에서 전혈구 및 감별혈구계산(CBC with D/C), 간기능검사, 신장기능검사 및 림프구아형검사(CD3, CD4, CD8, CDl6, CD56, CDl9)를 시행 하였으며, 검사시기는 방사선치료 직전과 4500 cGy - 5000 cGy 선량에서 동일 검사를 반복시행 하였으며, 1980cGy에서는 전혈구 및 감별혈구계산만 시행하였다. 결과 : 전체환자의 치료전 백혈구 총수는 7017이었으며 방사선치료직후 평균 4470으로 감소하였다(p=0.0000). 감별혈구계산에서는, 림프구수는 평균 2047 에서 537 로(p=0.0000) 로 감소하였고, 호중구, 호염구세포의 절대수도 통계학적으로 유의한 감소를 보였으나, 단핵세포는 변화가 없었으며, 호산구세포는 오히려 방사선치료후 증가하였으나 통계적인 의의는 없었다. 림프구아형에 대한 검사결과는, 모든아형의 절대수가 통계학적으로 유의한 감소를 보였으며, CD4/CD8비는 치료전 평균 1.09에서 0.99로 감소 하였으나 통계적인 유의성은 없었다. 전체 림프구에 대한 비율의 변화를 보면, B림프구(CD 19)는 감소하였으나, 그외 아형의 비율은 방사선치료후 변화를 보이지 않았다. 혈청면역글로불린은 초기 Ig, G, Ig A, Ig M 모두 정상값보다 눌은 수치였으며, 방사선치료에 따른 변화는 Ig M에서만이 통계적으로 유의한 감소를 보였으며, Ig G, A는유의한 변화가 없었다. 결론 : 흉부나 골반강부위의 방사선치료는 림프구의 급격한 저하를 초래하는 반면 단핵구등은 비교적 잘 유지 되었으며, 호산구는 오히려 증가 됨을 알수 있었으나, 인체의 면역과의 관계를 설명하기 위해서는 림프구의 기능변화가 함께 연구 되어져야 하겠다.

• Molecules and Cells
• /
• 제42권3호
• /
• pp.228-236
• /
• 2019

CD4 T cells differentiate into $ROR{\gamma}t/IL$-17A-expressing cells in the small intestine following colonization by segmented filamentous bacteria (SFB). However, it remains unclear whether SFB-specific CD4 T cells can differentiate directly from naïve precursors, and whether their effector differentiation is solely directed towards the Th17 lineage. In this study, we used adoptive T cell transfer experiments and showed that naïve CD4 T cells can migrate to the small intestinal lamina propria (sLP) and differentiate into effector T cells that synthesize IL-17A in response to SFB colonization. Using single cell RT-PCR analysis, we showed that the progenies of SFB responding T cells are not uniform but composed of transcriptionally divergent populations including Th1, Th17 and follicular helper T cells. We further confirmed this finding using in vitro culture of SFB specific intestinal CD4 T cells in the presence of cognate antigens, which also generated heterogeneous population with similar features. Collectively, these findings indicate that a single species of intestinal bacteria can generate a divergent population of antigen-specific effector CD4 T cells, rather than it provides a cytokine milieu for the development of a particular effector T cell subset.

• 한국전기전자재료학회:학술대회논문집
• /
• 한국전기전자재료학회 2004년도 하계학술대회 논문집 Vol.5 No.2
• /
• pp.857-860
• /
• 2004

Cubic CdS thin film with the strongest XRD peak (111) at diffraction angle $(\theta)$ of 26.5 was well made at substrate temperature of $150^{\circ}C$. At that time, lattice constant a of the thin film was $5.79{\AA}$, grain size of that was more over ${\mu}m$ and it's resistivity was over $10^3{\Omega}cm$. And the peak of diffraction intensityat miller index (111) of CdS:In thin film with dopant In of 1 atom% was shown higher about 20 % than undoped CdS thin film. Also, CdS:In thin film had in part hexagonal structure among cubic structure as secondary phase. Lattice constant of a and grain size of secondary phase of the film with dopant In of 1 atom% was $5.81{\AA}$ and around $1{\mu}m$ respectively The lowest resistivity of $5.1{\times}10^{-3}{\Omega}cm$ was appeared on dopant In of 1.5 atom%. Optical band gap of undoped CdS thin film was 2.43 eV and CdS:In thin film with dopant In of 0.5 atom% had the largest band gap 2.49 eV.

• 한국토양비료학회지
• /
• 제47권1호
• /
• pp.41-47
• /
• 2014

Agricultural soils surrounding mine areas in South Korea are often contaminated with multiple metals such as Cd, Pb and Zn. It poses potential risks to plants, soil organisms, groundwater, and eventually human health. The aim of this study was to examine the changes in phytoavailability of Cd, Cu, Pb and Zn after application with calcined eggshell (CES; 0, 1, 3, and 5% W/W) in an agricultural soil contaminated by mine tailings. The contents of Cd, Cu, Pb and Zn in soils were 8.79, 65.4, 1602, and $692mgkg^{-1}$ (aqua regia dissolution), respectively. The experiments were conducted with lettuce (Lactuca sativa L. var. longifolia) grown under greenhouse conditions during a 30-d period. $NH_4NO_3$ solution was used to examine the mobile fraction of these metals in soil. The application of CES dramatically increased soil pH and inorganic carbon content in soil due to CaO and $CaCO_3$ of CES. The increased soil pH decreased the mobile fraction of Cd, Pb, Zn: from 3.49 to < $0.01mgkg^{-1}$ for Cd, from 79.4 to $1.75mgkg^{-1}$ for Pb, and from 29.6 to $1.13mgkg^{-1}$ for Zn with increasing treatment of CES from 0 to 5%. In contrast, the mobile fraction of Cu was increased from 0.05 to $3.08mgkg^{-1}$, probably due to the formation of soluble $CuCO_3{^0}$ and Cu-organic complex. This changes in the mobile fraction resulted in a diminished uptake of Cd, Pb and Zn by lettuce and an increased uptake of Cu: from 4.19 to < $0.001mgkg^{-1}$ dry weight (DW) for Cd, from 0.78 to < $0.001mgkg^{-1}$ DW for Pb, and from 133 to $50.0mgkg^{-1}$ DW for Zn and conversely, from 3.79 up to $8.21kg^{-1}$ DW for Cu. The increased contents of Cu in lettuce shoots did not exceed the toxic level of $>25mgkg^{-1}$ DW. The mobile contents of these metals in soils showed a strong relationship with their contents in plant roots and shoots. These results showed that CES effectively reduced the phytoavailability of Cd, Pb, and Zn to lettuce but elevated that of Cu in consequence of the changed binding forms of Cd, Cu, Pb, and Zn in soils. Based on these conclusions, CES can be used as an effective immobilization agent for Cd, Pb and Zn in contaminated soils. However, the CES should be applied in restricted doses due to too high increased pH in soils.

• Asian-Australasian Journal of Animal Sciences
• /
• 제14권3호
• /
• pp.338-345
• /
• 2001

An experiment was conducted to determine the optimal inclusion ratio of spray dried plasma protein (SDPP) and dried porcine solubles (DPS) for maximizing growth and improving immunity in weaned pigs. One hundred-fifty male (barrow) pigs were allotted in a completely randomized block design. Treatments were as follows: 1) control (6% SDPP), 2) S6D6 (6% SDPP+6% DPS), 3) S6D3 (6% SDPP+3% DPS), 4) S3D6 (3% SDPP+6% DPS) and 5) S3D3 (3% SDPP+3% DPS). Each treatment has 6 replicates with 5 pigs per replicate. Average daily gain (ADG) and average daily feed intake (ADFI) were highest, but not significantly different when pigs were fed a diet contained 6% SDPP and DPS from d 0 to 7 after weaning. Pigs fed the S6D3 diet showed better weight gain and feed intake than other treatments, especially compared with pigs fed S3D6 diet (p<0.05) from d 8 to 21 after weaning. For the overall experimental period, pigs fed the S6D3 diet showed the best improvement in ADG and ADFI. The digestibilities of dry matter (DM) and crude protein (CP) were higher in pigs fed the S6D6 diet than other diets from d 0 to 7 after weaning. However, pigs fed S6D3 diet showed higher DM, CP and essential amino acids (except methionine and arginine) digestibilities than pigs fed other diets from d 8 to 21 after weaning, although there was no significant difference. From d 8 to 21 after weaning, threonine, valine, isoleucine and leucine digestibilites were higher in S6D6 group, and phenyalanine, histidine, lysine and arginine digestibility were higher in S6D3 group than other groups. The ratio of CD4 and CD8 positive lymphocytes during the overall experimental period was independent of the ratio of SDPP and DPS. However, CD4+:CD8+ ratio was numerically lowered in pigs fed diet the S6D3 diet. Therefore, the present study suggests that an optimal inclusion ratio for maximizing growth performance and maintaining low immune status is 6% of SDPP and 3% of DPS in weaned pigs.

• 한국정보과학회논문지:시스템및이론
• /
• 제36권1호
• /
• pp.40-51
• /
• 2009

그래프 G의 쌍형 다대다 k-서로소인 경로 커버(쌍형 k-DPC)는 k개의 서로 다른 소스-싱크 쌍을 연결하며 그래프에 있는 모든 정점을 지나는 k개의 서로소인 경로 집합이다. 이 논문에서는 재귀원형군 G($cd^m$,d), $d{\geq}3$과 토러스에서 서로소인 경로 커버를 고려하여, 이분 그래프가 아니고 분지수가 $\delta$인 재귀원형군과 토러스는 고장 요소(정점이나 에지)가 f개 이하일 때 $f+2k{\leq}{\delta}-1$을 만족하는 임의의 f, $k{\geq}1$에 대하여 쌍형 k-DPC를 가짐을 보인다.