• 대한의생명과학회지
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• 제18권1호
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• pp.83-85
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• 2012

Vancomycin-resistant (VR)-E. faecium and VR-E. faecalis were isolated simultaneously from a rectal swab of a patient diagnosed with pneumonia in an intensive care unit (ICU). The patient was treated with various antibiotics including vancomycin. Only VR-E. faecium was continually isolated from the rectal swab at one and two weeks of the treatment. Identical vanA, IS1216V, and IS1542 genes were detected in both VR-E. faecium and VR-E. faecalis isolates which showed equal resistance against vancomycin and teicoplanin, but IS1251 was not detected. VR-E. faecium showed stronger multi-drug resistance than VE-E. faecalis. This result supports the reason why VR-E. faecium is one of the major pathogens in nosocomial infections.

• 대한화장품학회지
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• 제33권1호
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• pp.23-28
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• 2007

비타민 C는 강력한 환원제로서 멜라닌 색소의 합성을 저해하는 것으로 알려져 있다. 그러나 일반적인 화장품 제형에서는 낮은 안정성과 경피 흡수의 문제점으로 만족할 만한 효과를 나타내지 못한다. 본 연구에서는 안정성이 개선된 비타민 C의 유도체인 ascorbyl glucoside (AsAG)을 유효성분으로 하여 경피흡수를 증가시키고자 하였다. 본 실험에서는 유연하면서도 박막 형태의 배터리를 장착한 패치 화장품을 제조하고 안정성과 경피흡수성을 평가하였다. 피부에 낮은 전류를 증가하는 이온토포레시스를 활용하여 피부에 적용하는 전류의 세기를 증가시키면 물질의 경피흡수는 증가한다. 그러나 전류의 세기를 증가시키면 피부 부작용이 증가하기 때문에 본 연구에서는 한국인의 피부에 맞는 적절한 전류를 선택하여 피부 부작용을 최소화하였다. 이런 결과들을 바탕으로 유연하면서도 가벼운 박막 배터리를 개발하였으며, 2%의 AsAG을 함유한 이온토포레시스 패치의 안전성, 경피흡수정도, 미백효과 등을 검토한 결과 피부에 가하는 최적의 전류는 1.5 V의 배터리를 사용하여 피부 부작용과 경피흡수를 고려하여 평균 0.1 mA이었다. 또한 패치의 임상실험 결과 유의한 수준의 미백효과를 보였으며 피부 자극도도 통상의 화장품 수준을 나타냈다.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2012년도 춘계학술대회
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• pp.799-802
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• 2012

본 논문은 기존의 헬스케어 서비스의 한계를 극복하기 위해 최근 대두되고 있는 스마트 헬스케어 서비스(smart healthcare service)에 관한 연구이다. 스마트 헬스케어는 스마트폰의 기능에 맞추어 기초체력 운동 지수, 섭취 칼로리, 심박 체크 등의 다양한 서비스를 제공할 수 있지만, 최근에는 보건의료서비스에 특화시켜 환자와 의사가 직 간접적으로 진료를 할 수 있게끔 하는 스마트폰 환경에서의 원격진료 서비스가 부각되고 있다. 그러나 헬스케어를 위한 HL7 CDA 표준의 문서 교환방식은 실시간 데이터 획득을 요구하는 원격진료 서비스 환경에 적합하지 못하다. 이에 본 논문에서는 HL7v2.x의 트리거 이벤트를 통한 메시지 전송방식과 HL7 CDA RIM(Reference Information Model)을 응용하는 실시간 HL7 의료정보 전송 방안을 제안한다.

• Mass Spectrometry Letters
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• 제5권3호
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• pp.89-93
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• 2014

Lincomycin is one of the major species among the Pharmaceuticals and Personal Care Products (PPCPs) detected from the four major rivers in Korea. The structure characterization was performed of six degradation products of lincomycin formed under the irradiation of electron beam, and the degradation efficiency as a function of the various irradiation dose and sample concentration was investigated. Electron beam (10 MeV, 0.5 mA and 5 kW) experiments for the structural characterization of degradation products that are fortified with lincomycin, were performed at the dose of 10 kGy. The separation of degradation products and lincomycin was carried out using a C18 column ($2.1{\times}100$ mm, $3.5{\mu}m$), using gradient elution with 20 mM ammonium acetate and acetonitrile. The structures of six degradation products of lincomycin were proposed by interpretation of mass spectra and chromatograms by LC-MS/MS. The mass fragmentation pathways of mass spectra in tandem mass spectrometry were also proposed. Experiments were performed of the degradation efficiency as a function of the irradiation dose intensity and the initial concentration of lincomycin in an aqueous environment. In addition, increased degradation efficiency was observed with a higher dose of electron beam and lower concentration.

• 한국의료질향상학회지
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• 제8권2호
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• pp.208-217
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• 2001

Background : The objective of this study is proving the basic data for developing a management system for the discharges against medical advice(AMA) by identifying the characteristics of the AMA patients of an university hospital for 10 years. Methods : By using discharge abstract data base, we divided the total discharges(435,254) into two groups, discharge against medical advice and discharge with discharge order. We confirmed the characteristics of AMA group by analyzing discharge abstract data of the both groups by SAS software V6.12 and $x^2$ test. Medical records of AMA patients in the year 2000 were reviewed to identify the reasons for AMA which we couldn't extract from discharge abstract DB. Result : The total number of AMA for 10 years were 9,358(2.15%) and the AMA rate has been continuously decreased for 10 years. Male, admission through emergency room, discharges admission via other hospital, patients without operation during hospitalization, discharges in hopeless or not improved condition showed higher AMA rate. The AMA rate was higher as the age of the patients was higher, and the average length of stay was longer in AMA patients than in those with discharge order. The AMA rate in psychiatry was highest(14.3%) and it was higher in surgery departments than those of medical or other sections. The AMA rate varied by attending physicians even in the same department and it was statistically significant. Patients with the principal diagnosis of "medical observation and evaluation for suspected diseases" showed the highest AMA rate(15.5%), and that of schizophrenia or psychosis was the nest. One hundred twenty-one patients(19.5%) out of 622 AMA in 2000 discharged against medical advice for transfer to order health care facilities. Among them 71 patients(58.7%) discharged with their medical care information, such as copies of medical record, medical certificates, summaries, etc. Written oath of the patients discharged AMA was filed in their medical records in 466 cases(74.9%) although some of them were incomplete. Conclusion : Characteristics of AMA discharge could be used as the basic data in developing a system to manage the patients who have risk factors to leave the hospital against medical advice. By reducing number of patients leaving the hospital against medical advice we can increase satisfaction of medical providers and consumers.

• 간호행정학회지
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• 제4권1호
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• pp.73-88
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• 1998

The management of nursing resource is very important. that is because nursing staff accounts for 30-40% of total staff in a hospital and nurses provide patoents with attentive service for hours daily. The continuous turnover of nursing staff. however, impedes the quality-oriented nursing care, which will consequently leads to the loss of human and material resource in competitive society. This study aimed to calculate nurse's activity and compare the activity amount based on career experience. Futhermore it aimed to find factors which would influence 'quality weighed direct nursing activity amount'. Questionnaires and check lists for this study were distributed to nurses in a suburban hospital outside of Seoul from October 20 to November 14. 1997. The nursing activities were calculated according to professionality. independency and working hour. And then it were accumulated by quality score. The collected data was analyzed by statistical methods as t-test, ANOVA, correlation, multiple regression. The results of this study were as follows ; Firstly, carrel' experience had no influence on the quality weighed nursing activity amount. But the quality level of service of skilled nurses was higher than that of new nurses. Secondly, career was a variable affecting the quality in nursing service. So career was positively related to the quality of nursing care. Patient's disease severity and number of patient were positively correlated with weighed nursing activity amount. But job satisfaction was negatively correlated v:ith the amount. Thirdly, the independent variables which had significant influence on the weighed nursing activity amount were disease severity and the number of patients, The severity score and number of patient were directly proportional to the weighed nursing activity amount. This results indicated· that weighed nursing activity amount was influenced by the number of patient and patient's disease severity. The quality score of nursing services for experienced members is higher than that of new staff. But both new and skilled staff showed no difference in the quality weighed nursing activity amount. Internal and. external environment influences nursing activities. The quality of nursing services is very important factor in nursing activity. Therefore nursing managers should make an effort to improve nursing care quality through continuous research. Also they should try to maintain experience nurses and assign nursing staff appropriately with patient's severity and other relevant factors being considered. The quality-improved nursing care in the hospital will strengthen hospital's competitiveness.

• 한국지역사회생활과학회지
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• 제21권3호
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• pp.299-310
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• 2010

The purpose of this study was to develop a scale to assess a Korean home environment for middle childhood children. The subjects were 283 mothers of 6- to 8-year-old children in Korea. The method for data analysis included Mean, SD, $x^2$, Cramer's V, factor analysis, Pearson correlations, and Cronbach's $\alpha$. As a result, 45 items of the scale were found to be satisfactory in terms of item distribution and item discrimination(Cramer's discriminant coefficients ranged from .256-.615). Four factors with 21 items were extracted from the factor analysis. Subscales were 'academic stimulation(9)', 'acceptance(4)', 'child-centered environment(4)', 'basic care for daily routine(4)'. Analysis of the relation of this scale to SES, MC-HOME, and children's developmental functioning(cognitive, language, and social) showed acceptable concurrent validity. Internal consistency of this scale was high, including internal reliability of subscales. These results confirm this scale as a valid and reliable measure of the Korean home environment for middle childhood children.

• 한국해양공학회:학술대회논문집
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• 한국해양공학회 2002년도 추계학술대회 논문집
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• pp.119-123
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• 2002

Liquefied Natural Gas(LNG) continues to attract modern gas industries as well as domestic markets as their main energy source in the recent years. This is mainly because LNG is inherently cleaner and more energy efficiency than other fuels. Offshore LNG production plant is of interest to many oil producing companies all over the world. This article discuss about the production process encountered while developing such a production facility. Typical offshore oil and gas processing required for oil stabilization and other optional units that can be added to the facilities. The production process can broadly be divided into five major units namely, (i) Oil Stabilization unit, (ii) Gas Treatment unit, (iii) Methane Recovery unit, (iv) Distillation unit and (v) LNG Liquefaction unit. The process simulation was carried out for each unit with a given wellhead composition. The topside facilities of offshore LNG production plant will be very similar to the process adopted in offshore processing platform along with the typical onshore LNG production plant. However, the process design problems associated with FPSO motion to be taken care of while developing floating LNG production plant.

• 보건의료산업학회지
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• 제6권2호
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• pp.101-109
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• 2012

This study purposed to analyze the differences of cost, length of stay, and number of visits between patients who referred from clinics to a general hospital and patients who directly visit a general hospital. Study sample included 402 patients (177 patients who were not referred from clinics, 225 patients who referred from clinics) who visited the Dept. of Gastroenterology in a university hospital in Daejeon from January to June in 2007. Cost and patients' information were collected from Hospital Information System and medical record. SPSS v.12.0 was used for the statistical analysis. Multiple regression analysis found that for inpatients, location variables and malignant tumors of digestive organs had a significant influence on cost variable. For outpatients, a referring hospital type and visiting month had significant influences on total cost, and sex and visiting month (February) had significant relationship with number of visit. The study results help to understand the differences of patient care depending on whether they were referred from clinics or not. Hospital managements could use the results for marketing purposes, and it could provide valuable information for increasing the competitiveness of hospital in a given market.

• 조명전기설비학회논문지
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• 제28권6호
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• pp.60-67
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• 2014

Power system fault analysis is commonly based on well-known symmetrical component method, which describes power system elements by positive, negative and zero sequence impedance. The majority of fault in transmission lines is unbalanced fault, such as line-to-ground faults, so that both positive and zero sequence impedance is required for fault analysis. When unbalanced fault occurs, zero sequence current flows through earth and ground wires in overhead transmission systems and through cable sheaths and earth in underground transmission systems. Since zero sequence current distribution between cable sheath and earth is dependent on both sheath bondings and grounding configurations, care must be taken to calculate zero sequence impedance of underground cable transmission lines. In this paper, EMTP-based sequence impedance calculation method was described and applied to 345kV cable transmission systems. Calculation results showed that detailed circuit analysis is desirable to avoid possible errors of sequence impedance calculation resulted from various configuration of cable sheath bonding and grounding in underground cable transmission systems.