• 한국수산과학회지
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• 제48권4호
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• pp.432-438
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• 2015

This study examined the antimicrobial, antioxidant, and tyrosinase inhibitory activities of bioactive compounds extracted from two starfish, Asterina pectinifera and Asterias amurensis, using solvent extraction after $Protamex^{TM}$ hydrolysis. Methanol and acetone fractions collected by stepwise extraction from specimens were subjected to silica gel column chromatography (SGCC) (200 mesh and 400 mesh), followed by high-performance liquid chromatography (HPLC). Two fractions (7:3 and 5:5 chloroform : methanol ratio, v/v) eluted using silica gel column chromatography from the two starfishes showed higher antimicrobial activity against Propionibacterium acnes and dermatophyte fungi (Epidermophyton floccosum, Microsporum audouinii, Trichophyton ferrugineum, Trichophyton mentagrophytes, and Trichophyton rubrum), antioxidant activity ($EDA_{50}$, mg/mL), and tyrosinase inhibitory activity compared to the other fractions. The final fractions obtained from Asterina pectinifera (RT 7.53, 8.93, and 10.48 min) and Asterias amurensis (RT 5.02 min) by SGCC (400 mesh) and HPLC from two SGCC fractions (200 mesh) showed 8.94 and 15.59 mg/mL antioxidant activity ($EDA_{50}$) and 46.89 and 40.19 % tyrosinase inhibitory activity, respectively. Extracts from starfishes are potential cosmetic basic material.

• Natural Product Sciences
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• 제21권1호
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• pp.30-33
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• 2015

Anthocyanins are water soluble plant pigments which are responsible for the blue, red, pink, violet colors in several plant organs such as flowers, fruits, leaves and roots. In recent years, anthocyanin-rich foods have been favored as dietary supplements and health care products due to diverse biological activities of anthocyanins including antioxidant, anti-allergic, anti-diabetic, anti-microbial, anti-cancer and preventing cardiovascular disease. High-performance countercurrent chromatography (HPCCC) coupled with reversed-phase medium pressure liquid chromatography (RP MPLC) method was applied for the rapid and efficient isolation of cyanidin 3-glucoside (C3G) and peonidin 3-glucoside (P3G) from black rice (Oryza sativa L., Poaceae). The crude black rice extract (500 mg) was subjected to HPCCC using two-phase solvent system composed of tert-butyl methyl ether/n-butanol/ acetonitrile/0.01% trifluoroacetic acid (TBME/B/A/0.01% TFA, 1 : 3 : 1 : 5, v/v, flow rate - 4.5 mL/min, reversed phase mode) to give enriched anthocyanin extract (37.4 mg), and enriched anthocyanin extract was sequentially chromatographed on RP-MPLC to yield C3G (16.5 mg) and P3G (8.7 mg). The recovery rate and purity of isolated C3G were 76.0% and 98.2%, respectively, and those of P3G were 58.3% and 96.3%, respectively. The present study indicates that HPCCC coupled with RP-MPLC method is more rapid and efficient than multi-step conventional column chromatography for the separation of anthocyanins.

• Neonatal Medicine
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• 제18권2호
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• pp.409-411
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• 2011

In Korea, pulmonary surfactant (PS) replacement therapy in respiratory distress syndrome (RDS) was started in 1991 since when Surfacten$^{(R)}$ was imported from Japan. At the present time, Surfacten$^{(R)}$, Newfactan$^{(R)}$, Curosurf$^{(R)}$, and Infasurf$^{(R)}$ are available in Korea. The governmental health insurance covers the expense for multiple dose treatment since 2002 and the early prophylactic treatment (BW: <1,250 g or GP: <30 wks) since 2011. We undertook a multi-institutional collective study to evaluate the outcomes of PS over past 20 years in Korea (Period-I; 1990/91, P-II; 1996, P-III; 2002, and P-IV; 2007, P-V; 2010). There were 60 RDS neonates with PS treatment in P-I (16 hospitals), 1,179 in P-II (64), 1,595 in P-III (62), 1,921 in P-IV (57), and 3,160 in P-V (72). Decreased mortality rate, defined as the percentage of neonates who died within 28 days of birth, was seen between periods, P-V vs P-I, II, III, and IV (mortality rate: 10.1% vs. 40.0%, 30.0%, 18.7%, and 14.3%). We conclude that PS therapy contributed to improve remarkable outcome in RDS neonates over the last 20 years in Korea. However, more efforts should be made to optimize PS therapy for better outcome. Multiple PS doses for relapse and poor response, early prophylactic use, and better supportive care for pre-term infants are mandatory.

• International Journal of Advanced Culture Technology
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• 제6권2호
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• pp.86-99
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• 2018

This study examined the relationship between the demographic profiles of 260 staff nurses in the SPC Health Care Ministry Hospitals and their Transcultural Self-Efficacy (TSE) level on the Cognitive, Practical and Affective dimensions. To obtain the result, among the nine (9) demographic profile items, three (3) common positive predictors were considered, namely, 1) Educational attainment level; 2) Age; and 3) Willingness to work abroad in all three dimensions. While in the Practical and Affective dimensions, the number of years employed were a common negative predictor and in the Affective dimension, Gender of participants was added as the positive predictor. Therefore, there are some significant demographic characteristics of respondents influence to the transcultural self-efficacy. Further, based on the results of this diagnostic study, the researcher designed the One (1) year Cultural Competence Training Program for staff nurses. For future research, the researcher recommended to conduct a further study that will evaluate the effectiveness of the educational intervention by approaching a longitudinal study form administering the test and retest of TSET.

• Industrial Engineering and Management Systems
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• 제8권1호
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• pp.54-65
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• 2009

The existence of Internet revolutionized the computer and communications world. With the rising demand for accessing the Internet, the mobile technology has incorporated the use of Internet in mobile phones. Wireless Application Protocol (WAP) has combined two of the widest utilized technology today: mobile phones and Internet. This study aims to assess the existing WAP pages offered by the top service providers in the Philippines through usability testing experiments. The paper also aims to identify existing problems in WAP interface by focusing on the errors committed by the users. From the usability study, it was found out that common usability problems are wrong selection of links, unclear grouping of categories, wrong feedback, and redundant links. The type of service provider used is significant in determining the performance of users while experience in accessing WAP is insignificant.

• 한국직업건강간호학회지
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• 제14권1호
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• pp.16-23
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• 2005

Purpose: The Purpose of the study was to suggest how the health manager use to be easy return-to-work of injured workers. Method: The data were collected by the health managers working at the 103 companies over medium size in Incheon, Gyoung-gi and Seoul through interview and report by themselves and analyzed by SAS V8 through t-test. Result: 1. The health managers are consisted of 2 kinds, one is health manager such as physician(10%) or nurse(81%) and the other is safety manager. The former works at the manufacturing company(62.9%), the latter at the service one(42.4%). 2. Management and counseling of occupational and non-occupational diseases, and high risk workers, health education, emergency care, worksite rounding, guidance of personal protector use, and health promotion services were highly performed by health managers. Comparing to these, safety managers performed guidance of job safety, safety management. The difference of two kinds of manager was significant statistically not only the aspect of general job but also related job to the workers of return-to-work after accident. Conclusion: This result shows that health manager can function as a care manager to the workers after return-to-work for adaptation to their job and rehabilitation bio-psycho-socially. But health managers don't have any regulations of encouraging injured workers to get their job again officially.

• 한국인터넷방송통신학회논문지
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• 제13권3호
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• pp.127-133
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• 2013

산업사회의 발전에 필수적인 요소 중의 하나로서, 전력 에너지의 수요는 과학 기술의 발전에 따라 꾸준히 증가해오고 있다. 전력의 수요에 부응하기 위해, 고전압과 대용량을 감당할 전력설비기 필요하다. 튼튼한 바탕 위에서 전력을 생산 공급하기 위해서는 전기 시설은 신뢰성 있게 운전해야 한다. 전력 설비가 사고를 일으킬 경우 막대한 국가적 손실을 초래하게 된다. 국가 기간 산업 시설의 중추적인 기능을 하고 있는 전력 설비는 가능한 안정된 상태를 유지하면서 오랜 기간 동안 운전할 수 있어야 하며, 사고를 미리 예방할 수 있어야 한다. 전력을 전달하기 위한 수단으로서 사용되고 있는 케이블 설계 시 수명을 약 30년으로 간주하지만, 많은 경우의 실제 현장에서는 8~12년 정도에서 파괴 현상이 발생하여 재산상의 큰 피해를 초래한다. 본 논문은 운전 중 22kV 케이블 시스템의 열화 과정에 대한 연구를 통하여 열화의 원인을 파악하였으며, 와이블 분포만 따르는 것이 아니라 열열화 후 와이블 열화를 거쳐 부분 방전에 의하여 케이블이 파괴되는 것을 확인 할 수 있었다.

• Tuberculosis and Respiratory Diseases
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• 제52권2호
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• pp.156-165
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• 2002

연구배경: 기관내 관에 의한 합병증 중에서 기낭에 연관된 문제로 높은 기낭압은 기관 점막의 허혈성 손상을 초래하고 너무 낮은 기낭압은 상기도 분비물의 흡인과 환기 가스의 누출에 따른 환기 장애를 초래한다. 이러한 기낭과 관련된 문제들을 예방하기 위해서는 적절한 기낭압을 유지하는 것이 중요하다. 더욱이 장기간 기계호흡을 받는 환자에서는 환자의 호흡역학의 변화 등 여러 원인에 의해서 적절한 기낭압이 변할 수 있어 기낭압의 지속적인 감시 및 관리가 필요할 것으로 사료되나 이에 대한 연구 보고가 없었다. 이에 본 연구는 장기간 기계호흡을 받는 환자에서 기관내관의 기낭압의 변화를 알아 보고 기낭압의 지속적인 감시 및 관리의 필요성을 알아보고자 하였다. 방 법 : 호흡부전으로 14일 이상 장기간 기계호흡을 받는 환자를 대상으로 기관 내관 삽관 일부터 발관 일까지 매일 기낭 공기량의 변화에 따른 기낭압의 변화를 알아 보고 적절한 기낭압을 유지하기 위해 필요한 기낭 공기량을 측정하여 비교하였다. 결 과 : 기낭압은 삽관 일수에 따라 유의한 증가는 관찰되지 않았으나 적절한 기낭압을 유지 하기 위해서 필요한 기낭내 주입 공기량은 환자에 따라 1.9~6.9 cc 로써 다양하고 동일한 환자 내에서도 적절한 기낭압을 유지하기 위해 필요한 기낭내 주입 공기량의 변화가 심하고, 일정한 기낭 공기 3cc 주입시 측정된 기낭압의 변화가 평균 22 $cmH_2O$였다. 수은혈압계로 측정된 기낭압은 자동기낭압관리기로 측정된 기낭압과 정확히 일치하였다. 결 론 : 기낭압에 의한 합병증을 줄이기 위해서 일정한 공기량을 기낭내 주입하거나 간헐적인 기낭압의 측정으로는 적절한 기낭압을 지속적으로 유지 하는데 부적절하여 지속적인 기낭압의 측정 및 감시가 필요한 것으로 사료되며 이러한 목적으로 수은혈압계는 자동기낭압관리기를 대체하여 이용될 수 있을 것으로 사료된다.

• 대한지역사회영양학회지
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• 제25권5호
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• pp.374-385
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• 2020

Objectives: This study was conducted to examine the status of foodservice management, with special interest on sanitary and nutritional food service in elderly day care centers. Methods: A total of 79 employees who managed foodservice facilities in elderly day care centers were included in the survey. The contents of the questionnaire consisted of general characteristics, importance and performance of sanitary and nutrition management, the reasons for poor performance, factors necessary for improvement, and the employee's demand for support. Data analysis was conducted using the SPSS v25.0. Results: Sanitary management showed an average importance score of 4.84 ± 0.40 and a performance score of 4.70 ± 0.61 (t-value: 8.260). The item with the lowest performance score was personal sanitary management (4.58 ± 0.71). In nutrition management, the average importance score was 4.52 ± 0.68, and the performance score was 4.20 ± 1.00 (t-value: 9.609). There were significant differences between the average score of importance and performance in both areas. As a result of an Importance-Performance Analysis, items that were recognized as important but had relatively low performance was "personal hygiene", "ventilation" and "food storage". Also in the nutritional management area, "menu planning for disease management" and "checking the saltiness in the soup" etc. had very low performance with low importance recognition. The items shown in the "low priority" quadrant were those that required professional management skills. In the areas that demanded support in foodservice management, education about sanitary and safe institutional food service had the highest score (4.42 ± 0.74), and all other items showed a demand of 4 points or more. Conclusions: Foodservice managers recognize the importance of foodservice facility management but performance is relatively low. Institutional support is, therefore, needed to improve performance. For items with low importance, it seems necessary to improve awareness of the necessity of these items and to provide education in this regard. To gradually improve foodservice management, continuous provision of education and training in these areas are of great importance.

• Journal of Nutrition and Health
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• 제9권4호
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• pp.47-53
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• 1976

As the seriousness of hypertension in adults is increasingly recognized, attention is being focussed on its control through continuous health supervisions. Complications arising from high blood pressure exceed those of many other adult health problems and affect the nursing needs of these patients. In order to contribute to effective nursing care planning and improved health supervision, 248 medical records of hypertensive patients admitted to Internal Medicine at Ewha Medical Center from January 1971 to August 1976 were examined. Results were as fellows: 1. The sample group averaged 5.0% of the total number of patients admitted to internal medicine during the period studied. The proportion increased slightly with each successive year. 2. Patients with hypertension averaged 31.4% of all patients with cardiovascular discease. This proportion was stable over the period. 3. Hypertensive patients were primarily in their 40s. The average age was 55.1 years. 4. Women were most frequently affected in their 60s and men in their 40s. 5. The bloo pressure of these in their 30s was not well controlled on discharge. Rates for those in their 30s averaged 151.5/107mmhg, for those in their 40s 161.5/110mphg, and for those in their 60s 169/100mmhg. 6. Complications increased with each age range from the 40s to the 60s for both men and women. 7. Complications related to systolic hypertension occurred most frequently when the rate exceeded 200mmhg. Cerebral vascular accident was the primary complication, presenting implications for nursing intervention. 8. Complications related to diastolic hypertension occurred most frequently when the rate was in the $110{\sim}129mmhg$ range. C.V.A. again was the primary complication needing nursing care planning. 9. Diets ordered for patients were low salt 79.%, salt free 4.19%, diabetic 6.1%, and protein free ('no protein') 2.0%. Caloric, salt end protein levels were not defined. Recommendations based on the findings were directed to diet and other therapies.