• Title/Summary/Keyword: CAGE Model

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Comparative Study on Growth Patterns of 25 Commercial Strains of Korean Native Chicken

  • Manjula, Prabuddha;Park, Hee-Bok;Yoo, Jaehong;Wickramasuriya, Samiru;Seo, Dong-Won;Choi, Nu-Ri;Kim, Chong Dae;Kang, Bo-Seok;Oh, Ki-Seok;Sohn, Sea-Hwan;Heo, Jung-Min;Lee, Jun-Heon
    • Korean Journal of Poultry Science
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    • v.43 no.1
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    • pp.1-14
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    • 2016
  • Prediction of growth patterns of commercial chicken strains is important. It can provide visual assessment of growth as function of time and prediction body weight (BW) at a specific age. The aim of current study is to compare the three nonlinear functions (i.e., Logistic, Gompertz, and von Betalanffy) for modeling the growth of twenty five commercial Korean native chicken (KNC) strains reared under a battery cage system until 32 weeks of age and to evaluate the three models with regard to their ability to describe the relationship between BW and age. A clear difference in growth pattern among 25 strains were observed and classified in to the groups according to their growth patterns. The highest and lowest estimated values for asymptotic body weight (C) for 3H and 5W were given by von Bertalanffy and Logistic model 4629.7 g for 2197.8 g respectively. The highest estimated parameter for maturating rate (b) was given by Logistic model 0.249 corresponds to the 2F and lowest in von Bertalanffy model 0.094 for 4Y. According to the coefficient of determination ($R^2$) and mean square of error (MSE), Gompertz and von Bertalanffy models were suitable to describe the growth of Korean native chicken. Moreover, von Bertalannfy model was well described the most of KNC growth with biologically meaningful parameter compared to Gompertz model.

Effects of Olanzapine on the Schedule-Induced Polydipsic Rats (Olanzapine이 백서의 Schedule-Induced Polydipsia에 미치는 영향)

  • Lee, Gi-Chul;Lee, Kyung-Kyu;Chang, Hwan-Il;Lee, Jung-Ho;Kim, Hyun-Woo;Ha, Jun-Myung;Jeong, Jae-Hyun;Jeong, Hong-Kyung
    • Korean Journal of Biological Psychiatry
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    • v.6 no.2
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    • pp.240-245
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    • 1999
  • Object : This study was designed to evaluate the effects of olanzapine on the schedule-induced polydipsia(SIP) which is one of animal model of obsessive-compulsive disorder in rats. We administered olanzapine as a serotonin and dopamine blocking agent, fluoxetine as a selective serotonin reuptake inhibitor, and haloperidol for the dopamine antagonist to rats which showed schedule-induced polydipsic behavior. Methods : Spraque-Dawley rats weighing 200-250gm were individually housed and maintained and allowed free access to water. The rats were placed on a restricted diet. To induce polydipsia, rats were placed in the cage where a pellet dispenser automatically dispensed 90mg pellets on a fixed-time 60 seconds(FT-60s) feeding schedule over 150 minute test session per day. Water was available at all times in the cage. After 4 weeks of daily exposure to the FT 60s feeding schedule, experimental rats met a predetermined criterion for polydipsic behavior(greater than 3 times of water per session on average). 5 groups of rats were administered olanzapine(3mg/kg, i.p), olanzapine(10mg/kg, i.p), fluoxetine(5mg/kg, i.p.), haloperidol(0.1mg/kg, i.p.), and vehicle(1cc/kg, i.p.) for 3 weeks. The rats were tested once a week to access schedule induced polydipsic behavior. Water bottles were weighed before and after the 150-minute test session. The chronic effects of administration of experimental drugs on schedule induced polydipsic behavior were analyzed with ANOVA and Scheffe test as a posthoc comparison. In order to measure water consumption in non-polydipsic food-deprived rats, a separate group of rats(N=8) were individually housed and given a single bolus(14.5gm) of food per day which maintained them at their average body weight. Results and Conclusion : The results were as follows ; 1) After 4 weeks of scheduled feeding procedure, the experimental group showed significant differences than the bolus control in the amount of water consumption as compared with their average water intakes for 4 weeks. At the same periods, there were no differences between the experimental group and the bolus control in the body weight. 2) The fluoxetine group showed significant decrease in the amount of water intake over the 3 weeks of drug treatment as compared with their average amount of polydipsic water intakes. The olanzapine 3mg group showed significant decrease in the amount of water intake at 3rd weeks of drug treatment as compared with their average amount of polydipsic water intakes. The olanzapine 10mg group showed significant decrease in the amount of water intake at 2nd and 3rd weeks of drug treatment as compared with their average amount of polydipsic water intakes. However, the haloperidol group and the vehicle control group showed no changes of amounts of water intake for 3 weeks of treatment as compared with their average amount of polydipsic water intakes. 3) The fluoxetine group showed significantly lower amounts of water intake than the haloperidol group at 2nd weeks of drug treatment. And also the fluoxetine group showed significantly lower amounts of water intake than the haloperidol group and the vehicle control at 3rd weeks of drug treatment. The olanzapine 3mg group and the olanzapine 10mg group showed significantly lower amounts of water intake than the haloperidol group and the vehicle control at 3rd weeks of drug treatment. Above findings suggest that the fixed time feeding procedure for schedule-induced polydipsia as an animal model of obsessive compulsive disorder was effective to the evaluation of pharmacological challenge study. The authors assume that the serotonin hypothesis and the serotonin-dopamine interaction hypothesis are preferred to the dopamine hypothesis in the biological etiology of obsessive-compulsive disorder.

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Laboratory Experiments for Evaluating Necking Defects in Bored Piles Embedded in Sandy Soils Using Electromagnetic Waves (전자기파를 이용한 모래 지반에 설치된 현장타설말뚝의 네킹 결함 평가를 위한 실내 모형실험)

  • Lee, Jong-Sub;Kim, Youngdae;Yu, Jung-Doung
    • Journal of the Korean Geotechnical Society
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    • v.36 no.5
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    • pp.25-34
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    • 2020
  • Studies on nondestructive evaluation methods using electromagnetic waves have been commonly conducted to evaluate necking defects in bored piles. However, the propagation of electromagnetic waves are affected by water contents of surrounding materials. This study aims to investigate a suitability of electromagnetic waves for evaluating necking defects in bored piles embedded in sandy soils through laboratory experiments. Laboratory experiments are performed with a model pile having a necking defect. The diameter and length of model pile are 600 mm and 1 m, respectively, and the model pile is embedded in sandy soils with different water contents of 10%, 20%, and 30%. For the propagation of electromagnetic waves, a transmission line is configured in reinforcement cage using an electrical wire. The generation and detection of electromagnetic waves are conducted using a time domain reflectometer. Experimental results show that the peak amplitude of electromagnetic waves reflected at the necking defect decreases with an increase in the water content in sandy soils. In addition, the velocity of electromagnetic waves reflected from the toe of the model pile decreases win an increase in the water content. However, estimated locations of the necking defects are almost the same to that of the actual location of the necking defect. This study demonstrates that electromagnetic waves may be an effective method for evaluating necking defects in bored piles embedded in sandy soils

A Development of Infant Education Content for Animal Study (동물모형 학습을 위한 유아교육 콘텐츠 개발)

  • Lee, Kwang-Hyoung;Kim, Jung-Jae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.9
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    • pp.3510-3516
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    • 2010
  • In this paper to make young children to learn habits of the animals, crying, features, and English and Korean language, The system was developed to target the zoo various animals exist. If young child places a doll on the front of interesting animal, then young child can learn to look through the display connected to the model. The zoo is reducing the current appearance of the zoo, sensors that can recognize animals are attached to each cage. Attached to each sensor has a unique ID, If this approach recognizes a doll baby and will transmit a unique ID to the handler. Transmitted ID search the matched value sent from the database to retrieve the content and then the content is to be output through the output device. Also if the doll near the animal's room, young children find out animal sound and basic learning by multimedia effects. At the same time Korean, English, Mathematics are learned.

Experimental Implantation of Moving Actuator Type Total Artificial Heart in Sheep (양에서 시행한 이동작동기 형태(MOVING ACTUATOR TYPE) 인공심장의 삽입실험)

  • 김원곤
    • Journal of Chest Surgery
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    • v.28 no.6
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    • pp.533-541
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    • 1995
  • We recently developed a new model of moving actuator type totally implantable artificial heart[TIAH , based on the reverse position of the aortic and pulmonary conduits. This concept was proposed by one of surgeons in our team[Joon-Ryang Rho, M.D. to facilitate anatomical fitting of TIAHs. The moving actuator type electromechanical TIAH consisted of the left and right blood sacs, and the moving actuator including a motor. The inverted umbrella type polyurethane valves were used in the blood pumps. The aortic conduit was positioned anterior to the pulmonary conduit, which was the opposite relation to the conventional configuration of other total artificial hearts. We also adapted slip-in connectors for the aortic and pulmonary conduits. Two sheep , weighing 60-69 kg, were used for implantation. After small cervical incision and trans-sternal bilateral thoracotomy, cardiopulmonary bypass [CPB was administered using an American Optical 5-head pump and a membrane oxygenator[Univox-IC, Bentley . The anterior and posterior vena cavae were drained separately for venous return. An arterial return cannula was inserted into the right common carotid artery. During CPB, almost all of the ventricular myocardium was excised down to the atrioventricular groove and the artificial heart was implanted. We achieved 3-day survival in the first sheep and 2-day survival in the second. The day after operation the first sheep was successfully extubated and the second sheep was weaned from a respirator with good condition. After extubation, the first sheep walked around in the cage and fed herself. Serial laboratory and hemodynamic examinations were done during the experiments. In both sheep, pulmonary dysfunction was gradually developed, which was accompanied by acute renal failure. The animals were sacrificed and autopsy was done. Unexpected pregnnacy was incidentally found in both sheep. To our knowledge this is the first report of significant survival cases in the orthotopic implantation of electric TIAH using sheep.

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The Effects of Environmental Enrichment on Improvement of Motor Function in Parkinson's Disease Animal Model (풍요로운 환경(Environmental Enrichment)이 파킨슨병 동물 모델의 운동기능 향상에 미치는 효과)

  • Kang, Kyoung-Ah;Han, Sang-Sook;Kim, Kyung-Hee;Kim, Youn-Jung
    • Journal of Korean Biological Nursing Science
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    • v.10 no.2
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    • pp.176-183
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    • 2008
  • Purpose: The purpose of this study was to identify the effect of Environmental Enrichment (EE) on improvement of motor function in animal models of Parkinson's Disease. Methods: Male C57BL6 mice weighing 25-30 g, at the age of 12 wks were used in this study. The animals were injected MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridin, 20 mg/kg in saline, i.p.) 4 times a day at every 2 hr, and raised in EE cage for 14 days. On day 14, after behavior test, all mice were sacrificed for immunohistochemistry. All values were expressed as means$\pm$S.E.M. Statistical significance was evaluated using a one way ANOVA followed by Sheffe test. Results: There was a significant difference between the experimental group and the control group in the behavior test. Also EE significantly reduced of TH positive cell loss in Substantia nigra pars compacta as compared to the result of MPTP treatment. Conclusion: Based on these findings, it is reasonable to assume that the environmental enrichment prevents dopaminergic neuronal loss and improves disarrangement of motor function and behavioral disability induced by MPTP.

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Analysis of Conceptual Models and State-of-the-Art Technologies for the Automation of Telescoping Work in Horizontal Tower Cranes (수평형 타워크레인 텔레스코핑 작업의 자동화를 위한 개념 모델 및 요소기술 분석)

  • Lee, Sang-Ho;Kim, Young-Suk;Lee, Jeong-Ho
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.31 no.5D
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    • pp.705-717
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    • 2011
  • The number of horizontal tower cranes, major hoisting machineries for lifting approximately 50% of entire materials in construction projects, is rapidly increasing, but a number of accidents related to the tower cranes are being continuously occurred in construction sites as well. In particular, telescoping works in the horizontal tower cranes have showed the greatest safety concerns such as falls and collapses. It is due to the fact that tasks inserting a new mast in the space made after raising telescoping cage by fluid pressure and ascending it to the required height in the telescoping works include a series of dangerous factors in safety aspects, and might cause very serious and unexpected accidents in construction sites. The primary objective of this research is to propose two conceptual models for automating the telescoping work in horizontal tower crane and conduct their technical feasibility analyses. In this study, a design concept, a position control system using hydraulic cylinders is suggested as a better alternative for automating the telescoping work. Its potential safety improvement rate compared to the conventional method is also analyzed and presented in this study.

Genetic Effects of Polymorphisms in Myogenic Regulatory Factors on Chicken Muscle Fiber Traits

  • Yang, Zhi-Qin;Qing, Ying;Zhu, Qing;Zhao, Xiao-Ling;Wang, Yan;Li, Di-Yan;Liu, Yi-Ping;Yin, Hua-Dong
    • Asian-Australasian Journal of Animal Sciences
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    • v.28 no.6
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    • pp.782-787
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    • 2015
  • The myogenic regulatory factors is a family of transcription factors that play a key role in the development of skeletal muscle fibers, which are the main factors to affect the meat taste and texture. In the present study, we performed candidate gene analysis to identify single-nucleotide polymorphisms in the MyoD, Myf5, MyoG, and Mrf4 genes using polymerase chain reaction-single strand conformation polymorphism in 360 Erlang Mountain Chickens from three different housing systems (cage, pen, and free-range). The general linear model procedure was used to estimate the statistical significance of association between combined genotypes and muscle fiber traits of chickens. Two polymorphisms (g.39928301T>G and g.11579368C>T) were detected in the Mrf4 and MyoD gene, respectively. The diameters of thigh and pectoralis muscle fibers were higher in birds with the combined genotypes of GG-TT and TTCT (p<0.05). Moreover, the interaction between housing system and combined genotypes has no significant effect on the traits of muscle fiber (p>0.05). Our findings suggest that the combined genotypes of TT-CT and GG-TT might be advantageous for muscle fiber traits, and could be the potential genetic markers for breeding program in Erlang Mountain Chickens.

Evaluation of Optimum Dietary Threonine Requirement by Plasma Free Threonine and Ammonia Concentrations in Surgically Modified Rainbow Trout, Oncorhynchus mykiss

  • Yun, Hyeonho;Park, Gunjun;Ok, Imho;Katya, Kumar;Heung, Silas;Bai, Sungchul C.
    • Asian-Australasian Journal of Animal Sciences
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    • v.28 no.4
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    • pp.551-558
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    • 2015
  • This study was carried out to evaluate the dietary threonine requirement by measuring the plasma free threonine and ammonia concentrations in rainbow trout, Oncorhynchus mykiss after dorsal aorta cannulation. A total of 70 fish (average initial weight $506{\pm}8.2g$) were randomly distributed into each of the 14 net cages (5 fish/cage). After 48 hours (h) of feed deprivation, each group was intubated at 1% body weight with one of the seven L-amino acid based diets containing graded levels of threonine (0.42%, 0.72%, 0.92%, 1.12%, 1.32%, 1.52%, or 1.82% of diet, dry matter basis). Blood samples were taken at 0, 5, and 24 h after intubation. Post-prandial plasma free threonine concentrations (PPthr) of fish 5 h after intubation with diets containing 1.32% or more threonine were significantly higher than those of fish intubated with diets containing 1.12% or less threonine (p<0.05). Post-absorptive free threonine concentrations (PAthr) after 24 h of intubation of the fish with diets containing 0.92% or more threonine were significantly higher than those of fish intubated with diets containing 0.72% or less threonine. Post-prandial plasma ammonia concentrations (PPA, 5 h after intubation) were not significantly different among fish intubated with diets containing 1.12% or less threonine, except the PPA of fish intubated with diet containing 0.42% threonine. Broken-line model analyses of PPthr, PAthr, and PPA indicated that the dietary threonine requirement of rainbow trout should be between 0.95% (2.71) and 1.07% (3.06) of diet (% of dietary protein on a dry matter basis).

Experimental Study on the Damping Estimation of the 5×5 Partial Fuel Assembly (5×5 부분핵연료 집합체의 감쇠추정을 위한 실험적 연구)

  • Lee, Kang-Hee;Yoon, Kyung-Ho;Song, Kee-Nam
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.16 no.2 s.107
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    • pp.163-168
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    • 2006
  • The PWR Nuclear Fuel assembly consists of more than 250 fuel rods that are supported by leaf springs in the cells of more than 10 Spacer Grids (SG) along the rod length. Since it is not easy to conduct mechanical tests on a full-scale model basis, the small-scaled rod bundle $(5\times5)$ which is called partial fuel assembly is generally used for various performance tests during the development stage. As one of the small-scaled tests, a flow test should be carried out in order to verify the performance of the spacer grid to obtain the Flow-Induced Vibration (FIV) characteristics of the scaled fuel assembly over the specified flow range. A vibration test should be also performed to obtain the modal parameters of the assembly prior to the flow test. In this study, we want to develop the estimation procedure of the damping ratio for the scaled test assembly. For the damping factor of the partial fuel assembly and the grid cage at the first vibration mode, as one of the vibration tests, a so-called pluck testing has been performed in air as a preliminary test prior to in-flow damping measurement test. Logarithmic decrement method is used for calculation of the damping ratio. Estimated damping ratio of the partial fuel assembly is about $0.7\%$ with reasonable error of $2\%$ for the previous results. Nonlinear behavior of the partial fuel assembly might be stem mainly from the rod-grid support configuration.