• Title/Summary/Keyword: C242T

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Association of Genetic Polymorphisms of Estrogen Receptor with Litter Size using PCR-RFLP in Yorkshire Swine (Yorkshire종 돼지에서 PCR-RFLP을 이용한 Estrogen Receptor의 유전적 다형과 산자수간의 관련성)

  • Kim, J.E.;Song, W.C.;Choi, B.D.;Kho, Y.;Park, S.S.;Hong, K.C.
    • Journal of Animal Science and Technology
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    • v.45 no.4
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    • pp.523-528
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    • 2003
  • This study was performed to investigate a possible association of the porcine estrogen receptor(ER) locus with the total number of born(TNB) and number of born alive(NBA) in Yorkshire pigs. Using DNAs extracted from 242 Yorkshire pigs, the ER genotype was determined by PvuII PCR-RFLP. The ER allele frequencies of two types of A and B were 0.39 and 0.61, respectively. The least squares means of the litter size by ER genotype was evaluated. The TNB and NBA were found to be associated with an specific ER allele. The genotype at the porcine ER locus has an application potential for marker-assisted selection for litter size in pigs.

Physical Properties of High-Solid Coatings with Acrylic Resins Containing Acetoacetoxy Group and HDI-Trimer (Acetoacetoxy기 함유 아크릴수지와 HDI-Trimer에 의한 하이솔리드 도료의 도막물성)

  • You, Hyuk-Jae;Chung, Dong-Jin;Hahm, Hyun-Sik;Park, Hong-Soo;Kim, Seong-Kil
    • Journal of the Korean Applied Science and Technology
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    • v.20 no.3
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    • pp.237-242
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    • 2003
  • The high-solid coatings were prepared by blending the synthesized acrylic resin in the previous paper and hexamethylene diisocyanate-trimer and curing it at room temperature. The characterization of the films of the prepared coatings was performed. The impact resistance, $60^{\circ}C$ specular gloss, cross-hatch adhension, and heat resistance of the films proved to be good, and the pencil hardness and drying time proved to be slightly poor. Especially, there was a remarkable improvement in the heat resistance. This improvement may stem from the regular arrangement of ethyl groups introduced into the acrylic resin. From a viscoelastic measurement using a rigid-body pendulum, curing was accelerated with the $T_g$ value. With the increase in $T_g$, log damp value was lowered and dynamic viscoelasic $T_g$ of a cured film was increased.

PZT-PMN Ceramics for Large Displacement Piezoelectric Devices

  • Lim, Kee-Joe;Park, Jae-Yeol;Lee, Jong-Sub;Kang, Seong-Hwa;Kim, Hyun-Hoo
    • Transactions on Electrical and Electronic Materials
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    • v.5 no.2
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    • pp.76-80
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    • 2004
  • Piezoelectric and dielectric properties as functions of x and y mole ratio in yPb(ZrxTil-x)O$_3$(1-y)Pb(Mn$\_$1/3/Nb/2/3/)O$_3$, ceramics, PZT-PMN, are investigated for large displacement piezoelectric devices. From the experimental results, when y is 0.95 and x is 0.505, the piezoelectric and dielectric properties are maximum, that is, electromechanical coupling coefficient(kp), piezoelectric strain constant(d$\_$33/), permittivity($\varepsilon$$\_$33/$\^$T//$\varepsilon$$\_$0/), and Curie temperature are 58 %, 272 pC/N, 1520 and about 350$^{\circ}C$, respectively. Also, when y is 0.90 and x is 0.50, their properties are 56 %, 242 pC/N, 1220, and 290$^{\circ}C$, respectively. As MgO dopant is added from 0 wt% to 1 wt%, kp increases to 63 % and Qm decreases to 500 at the MgO dopant of 0.1 wt%, and then kp decreases to 57 % as MgO is added.

Fabrication and Properties of $(Pb_{1-x}C_{ax})((Co_{\frac{1}{2}}W_{\frac{1}{2}})_yTi_{1-y})O_3+(MnO_2, NiO)$ piezoelectric ceramic (압전세라믹 $(Pb_{1-x}C_{ax})((Co_{\frac{1}{2}}W_{\frac{1}{2}})_yTi_{1-y})O_3+(MnO_2, NiO)$)

  • Mun, Dong-Jin;Do, Si-Hong;Jang, Ji-Won
    • The Journal of the Acoustical Society of Korea
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    • v.6 no.4
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    • pp.55-63
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    • 1987
  • Modified $PbTiO_3$ piezoelectric ceramics added with 0.2, 0.25, 0.3 mol of $CaCO_3$ and 0.04 mol of $(Co_{\frac{1}{2}}W_{\frac{1}{2}})$ and 0.05 mol of $MnO_2$ and NiO have been fabricated. These ceramics can be poled sufficiently within 10 minutes at $100^{\circ}C$ under about d.c. field of 40 kv/cm. Detailed measurement was performed on dielectric constants, cutie temperatures, elastic and piezoelectric properties and coupling factors for the fabricated ceramics. The most value of the piezoelectric coupling factors was coupling factor of thickness mode kt and its value for 0.25 mol of Ca was about $45\%$. Dielectric constants of $\varepsilon_{33}^T$ and $\varepsilon_{11}^T$ for 0.25 mol of Ca were 242 and 260, and coupling factor ratio (kt/Kp) and Qm were 6 and 357 respectively.

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Photocurrent study on the splitting of the valence band and growth of $Cdln_2Te_4$ single crystal by Bridgman method (Bridgman법에 의한 $Cdln_2Te_4$단결정의 성장과 가전자대 갈라짐에 대한 광전류 연구)

  • 홍광준;이관교;이봉주;박진성;신동찬
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.13 no.3
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    • pp.132-138
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    • 2003
  • A stoichiometric mixture for $CdIn_2Te_4$ single crystal was prepared from horizontal electric furnace. The $CdIn_2Te_4$ single crystal was grown in the three-stage vertical electric furnace by using Bridgman method. The $CdIn_2Te_4$ single crystal was evaluated to be tetragonal by the power method. The (001) growth plane of oriented $CdIn_2Te_4$ single crystal was confirmed from back-reflection Laue patterns. The carrier density and mobility of $CdIn_2Te_4$ single crystal measured with Hall effect by van der Pauw method are $8.61\times 1016 \textrm {cm}^{-3}$ and 242 $\textrm{cm}^2$/V.s at 293 K, respectively. The temperature dependence of the energy band gap of the $CdIn_2Te_4$ single crystal obtained from the absorption spectra was well described by the Varshni's relation, $1.4750ev - (7.69\times10^{-3})\; ev/k)\;T^2$/(T + 2147k).The crystal field and the spin-orbit splitting energies for the valence band of the $CdIn_2Te_4$ single crystal have been estimated to be 0.2704 eV and 0.1465 eV, respectively, by means of the photocurrent spectra and the Hopfield quasicubic model. These results indicate that the splitting of the $\Delta$so definitely exists in the $\Gamma_7$ states of the valence band of the $CdIn_2Te_4$ single crystal. The three photocurrent peaks observed at 10 K are ascribed to the $A_{1-} B_{1-}$ and Cl-exciton peaks for n = 1.

Mitochondrial D-Loop Variations for Discrimination of Commercial Korean Native Chicken Populations

  • Sultana, Hasina;Hoque, Md. Rashedul;Seo, Dong-Won;Kang, Bo-Seok;Heo, Kang-Nyeong;Jo, Cheorun;Lee, Jun-Heon
    • Korean Journal of Poultry Science
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    • v.39 no.4
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    • pp.311-315
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    • 2012
  • The increasing demand for Korean native chicken meat indicates that the discovery of haplotypes is very important from both economic and conservation points of view. In this study, mtDNA D-loop sequences from two crossbred Korean native chicken populations of 138 individuals were investigated. Twenty six nucleotide substitutions were identified from sequence analysis and were classified into 12 haplotypes. The haplotype H_8 represents 73.47% of Woorimatdag (chicken population) sequences, which were identified in all five Woorimatdag chicken populations investigated. The H_7 haplotype (Dhap1) for D population covers 45% sequences, which indicate maternal inheritance from black Korean native chicken. On the other hand, Chap3 and Chap4 for C population are specific haplotypes, as H_5 and H_2, respectively. Based on the network profiles, six SNPs (C199T, A239G, G242A, A291G, T330C and C391A) of the D-loop region are effective markers for discrimination between Woorimatdag and Hanhyup chicken populations. Also, the phylogenetic analyses of Woorimatdag and Hanhyup chicken populations were used to identify the genetic relationships among the haplotypes. The results presented here can be used for developing molecular markers to discriminate between two commercial Korean native chickens.

Projection of Future Heating and Cooling Degree Days over South Korea under the IPCC SRES Scenarios: An Experiment with CCSM3 and MM5 Models (IPCC SRES 시나리오에 따른 우리나라의 미래 냉난방도일 전망: CCSM3와 MM5 모델 활용)

  • Choi, Jin Young;Song, Chang Kun;Kim, Deok Rae;Hong, Sung Chul;Hong, Yoo Deog;Lee, Jae Bum
    • Journal of Climate Change Research
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    • v.4 no.2
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    • pp.141-158
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    • 2013
  • In this study, the projection of future heating and cooling degree days (HDDs and CDDs) has been conducted over South Korea for the period 1996~2005 with 2046~2055 and 2091~2100, using CCSM3 and MM5 simulations driven by the six IPCC SRES emission scenarios (A2, A1B, A1FI, A1T, B1, and B2). Annual mean surface air temperature increases by $1.2{\sim}3.4^{\circ}C$ at the end of the 21st century comparing to the present-day (1996~2005) in South Korea. HDDs decrease by 8~25% and CDDs increase up to 242~1,448% with corresponding changes in temperature. These increases and decreases also change the duration of HDDs and CDDs. HDDs duration decreases by 1 month, while the expansion of CDDs duration is much longer than 2 months. Thus, projected future HDDs and CDDs changes appear that cooling energy demand in summer season would increase and heating energy demand in winter would decrease in the future. Especially, these remarkable changes would be obvious at high mountain area, Gangwon-do and at south area, Jeju island. In the sense of future energy supply and policy, electrical energy for cooling in summer could be getting much more its importance rather than fossil energy used for heating in winter.

Anti-Obesity Effects of Mixture of Cheese, Fermented Red Ginseng and Rubus coreanus Miquel (홍삼·복분자 혼합 발효물을 첨가한 치즈의 항비만 효과)

  • Lee, Da young;Kim, Nam Seok;Kim, Ha Rim;Kim, Min Sun;Lee, Chang Hyun;Oh, Mi Jin;Oh, Chan Ho;Kim, Jong Suk;Kim, Myung Soon;Kwon, Jin
    • The Korean Journal of Food And Nutrition
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    • v.31 no.2
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    • pp.242-251
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    • 2018
  • This study was investigating the anti-obesity effects of diets with a mixture of cheese, red ginseng and fermented mature fruit of Rubus coreanus Miquel. We fed the experimental diets (SC5, SC10) supplemented with 5% or 10% cheese containing of fermented mixture, then orally administered the extract of fermented mixture (RB100, RB300) at a concentration of 100 or 300 mg/kg body weight to SD rats with high fat diet (HFD). The results were as follows: Sample cheese groups decreased visceral fat mass and adipocyte size of stomach compared to that of HFD group. Additionally, lipid droplets of liver in sample cheese groups were smaller than that in HFD group. The serum triglyceride (TG), total cholesterol (tChol), glucose, leptin, and insulin levels in sample cheese group were lower than that in HFD group. But, the serum adiponectin and HDL-cholesterol (cHDL) levels were higher than that in HFD group. These results suggest that fermentation of red ginseng and Rubus coreanus mixed with cheese might be helpful in preventing obesity in high fat diet-fed rats.

Characterization of Miniimonas sp. S16 isolated from activated sludge (활성슬러지로부터 분리된 Miniimons sp. S16 세균의 특성)

  • Koh, Hyeon-Woo;Kim, Hongik;Park, Soo-Je
    • Korean Journal of Microbiology
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    • v.55 no.3
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    • pp.242-247
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    • 2019
  • Biological factors (e.g. microorganism activity) in wastewater treatment plant (WWTP) play essential roles for degradation and/or removal of organic matters. In this study, to understand the microbial functional roles in WWTP, we tried to isolate and characterize a bacterial strain from activated sludge sample. Strain S16 was isolated from the activated sludge of a municipal WWTP in Daejeon metropolitan city, the Republic of Korea. The cells were a Gram-stain-positive, non-motile, facultative anaerobe, and rod-shaped. Strain S16 grew at a temperature of $15{\sim}40^{\circ}C$ (optimum, $30^{\circ}C$), with 0~9.0% (w/v) NaCl (optimum, 1.0~2.0%), and at pH 5.5~9.0 (optimum, pH 7.0~7.5). Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain S16 was most closely related to the unique species Miniimonas arenae NBRC $106267^T$ (99.79%, 16S rRNA gene sequence similarity) of the genus Miniimonas. The cell wall contained alanine, glutamic acid, serine, and ornithine. Although the isolation source of the type strain NBRC $106267^T$ which considered as a marine microorganism is sea sand, that of strain S16 is terrestrial environment. It might raise an ecological question for habitat transition. Therefore, comparative genome analysis will be valuable investigation for shedding light on their potential metabolic traits and genomic streamlining.

Polymorphisms in the TNF-α Gene and Extended HLA and TNF-α Haplotypes in Koreans (한국인에서의 TNF-α 유전자 다형성과 HLA/TNF-α 일배체형의 분포)

  • Park, Yoon June;Park, Hye Jin;Park, Myoung Hee
    • IMMUNE NETWORK
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    • v.2 no.4
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    • pp.242-247
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    • 2002
  • Background: Tumor necrosis factor-alpha (TNF-$\alpha$) is known to play an important role in various conditions such as inflammation, autoimmunity, apoptosis, insulin resistance and sleep induction. Five single nucleotide polymorphisms (SNPs) have been known to affect the transcriptional activities of TNF-$\alpha$: -1,031T/C, -863C/A, -857C/T, -308G/A and -238G/A. Methods: We have investigated 5 SNPs of the promoter region of TNF-$\alpha$ gene, the distribution of 5-locus TNF-$\alpha$ haplotypes, and their haplotypic associations with previously typed HLA-A, -B and -DRB1 loci in 107 healthy unrelated Koreans. TNF-$\alpha$ SNPs were typed using PCR-single-strand conformation polymorphism (SSCP) and PCR-restriction fragment length polymorphism (RFLP) methods. Results: The allele frequencies of -1,031C, -863A, -857T, -308A, and-238A, which are known as the high-producer-type, were 19.3%, 15.9%, 14.0%, 5.9%, and 2.9%, respectively. The frequency of -308A allele, known to be associated with autoimmune diseases, was 5.9% in Koreans which was lower than Caucasians (14~17%) and somewhat higher than Japanese (1.7%). Five most common TNF-$\alpha$ haplotypes (-1,031/-863/-857/-308/-238) comprised over 95% of total haplotypes: TCCGG (58.4%), CACGG (14.8%), TCTGG (13.7%), TCCAG (5.3%), and CCCGA (3.1%). Strong positive associations (P<0.001) were observed between TCCGG and B62; between CACGG and B51, $DRB1^*0901$; between TCTGG and B35, B54, B59, $DRB1^*1201$; and between TCCAG and A33, B58, $DRB1^*0301$, $DRB1^*1302$. Five most common extended haplotypes (>3%) comprised around 16% of total haplotypes: A33-B58-TCCAG-$DRB1^*1302$, A24-B52-TCCGG-$DRB1^*1502$, A33-B44-TCCGG-$DRB1^*1302$, A24-B7-TCCGG-$DRB1^*0101$, and A11-B62-TCCGG-$DRB1^*0406$. The distribution of extended HLA and TNF-$\alpha$ haplotypes showed that most of HLA haplotypes were almost exclusively associated with particular TNF-$\alpha$ haplotypes. Conclusion: The results obtained in this study would be useful as basic data for anthropologic studies and disease association studies in Koreans.